Fluconazole combined with Melphalan Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tumour Lysis Syndrome Other Serious 11/4/2007 56 Male 155 lb 7/31/2009 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/12/2007 Male 223 lb 8/17/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/12/2007 Male 223 lb 8/18/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/12/2007 Male 223 lb 8/25/2009 Consumer United States
Primary
Secondary
Concomitant
Hypertension Other Serious 12/16/2008 15 Female 99 lb 8/27/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/12/2007 Male 223 lb 8/28/2009 Consumer United States
Primary
Secondary
Concomitant
Delirium Hospitalization 8/18/2009 Female 196 lb 8/28/2009 Netherlands
Primary
Secondary
Concomitant
Delirium Hospitalization 8/18/2009 Female 196 lb 9/14/2009 Netherlands
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 50 Female 12/7/2009 Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/14/2004 Male 1/12/2010 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/2/2002 Female 125 lb 1/13/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2005 Male 136 lb 1/15/2010 Physician United States
Primary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 1/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/30/2001 Female 115 lb 1/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 11/1/2005 Female 1/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 4/15/2005 Male 195 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 10/11/2004 Female 195 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2000 Male 2/11/2010 Physician United States
Primary
Concomitant
Tooth Loss Other Serious 1/1/2000 Female 140 lb 2/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/9/2002 Male 136 lb 2/15/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/15/2005 Male 209 lb 2/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 Female 125 lb 3/17/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/18/2010 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2004 Female 195 lb 3/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Death Unknown 3/16/2010 Brazil
Primary
Secondary
Concomitant
Cardiotoxicity Death Unknown 3/16/2010 Brazil
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Death Unknown 3/16/2010 Brazil
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2000 Male 3/22/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 Female 3/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/30/2001 Female 115 lb 3/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/15/2005 Male 209 lb 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 Female 3/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/2000 Female 140 lb 3/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 Female 125 lb 3/30/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/12/2005 Male 136 lb 3/30/2010 Physician United States
Primary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 4/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/22/2008 64 Male 4/5/2010 Other Health Professional United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 3/18/2010 56 Male 4/7/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/2/2000 Female 4/7/2010 Other Health Professional United States
Primary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 4/9/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/12/2005 60 Male 136 lb 4/9/2010 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 1/1/2004 64 Female 195 lb 4/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 3/17/2010 54 Female 165 lb 4/14/2010 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 3/24/2010 60 Male 172 lb 4/15/2010 Consumer United Kingdom
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 4/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 4/28/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 4/29/2010 United States
Primary
Secondary
Concomitant
Syncope Other Serious 3/17/2010 54 Female 165 lb 5/4/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Disorder Other Serious 1/1/2002 Male 5/4/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/15/2005 50 Male 209 lb 5/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 12/2/2009 5/10/2010 Other Health Professional Italy
Primary
Concomitant
Pyrexia Other Serious 9 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 5 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 9 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 11 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 11 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 5 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 13 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 1 Unknown 5/4/2010 United States
Primary
Secondary
Concomitant
Sepsis Death 7 5/4/2010 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 2 5/4/2010 Physician United States
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 5/10/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/2/2000 Female 5/12/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2002 58 Female 115 lb 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death Unknown 5/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 5/26/2010 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 5/28/2010 United States
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 6/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 1/1/2004 64 Female 195 lb 6/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/11/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2002 58 Female 115 lb 6/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/2/2000 Female 6/18/2010 Other Health Professional United States
Primary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 6/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/22/2010 United States
Primary
Secondary
Concomitant
Total Lung Capacity Decreased Other Serious 1/1/2002 65 Male 6/30/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Life Threatening 48 Male 6/23/2010 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 7/1/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Sepsis Death 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Death 7/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 7/5/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/25/2005 50 Male 209 lb 7/5/2010 United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 12/2/2009 7/5/2010 Other Health Professional Italy
Primary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 7/8/2010 United States
Primary
Secondary
Concomitant
Wound Treatment Other Serious 1/1/2000 52 Female 140 lb 7/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 8/26/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 8/26/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Engraftment Syndrome Death Unknown 8/26/2010 Korea, Republic Of
Primary
Secondary
Concomitant
Skin Exfoliation Hospitalization 8/1/2010 85 Male 196 lb 9/16/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 Female 9/24/2010 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 7/1/2007 52 Female 125 lb 9/29/2010 United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 9/29/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/25/2005 9/30/2010 United States
Primary
Secondary
Concomitant
Vasculitis Hospitalization 8/1/2010 85 Male 196 lb 10/1/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2002 58 Female 115 lb 10/4/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 Female 10/13/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2002 58 Female 115 lb 10/15/2010 United States
Primary
Secondary
Concomitant
Pruritus Hospitalization 9/30/2009 18 Female 137 lb 10/18/2010 Physician Japan
Primary
Concomitant
Vasculitis Hospitalization 8/23/2010 85 Male 121 lb 10/20/2010 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2000 Female 11/11/2010 Other Health Professional United States
Primary
Concomitant
Wound Other Serious 2/23/2005 47 Male 190 lb 11/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vasculitis Hospitalization 8/1/2010 85 Male 196 lb 11/17/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/11/2009 54 Male 152 lb 11/23/2010 Consumer Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 3/1/2009 54 Male 152 lb 11/24/2010 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 6/8/2010 63 Female 192 lb 12/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pseudomonal Sepsis Life Threatening 11/7/2010 49 Female 97 lb 12/30/2010 Physician Japan
Primary
Secondary
Concomitant
Shock Death 49 Male 2/28/2011 Other Health Professional Spain
Primary
Secondary
Hypoaesthesia Other Serious 7/2/2003 55 Male 187 lb 3/17/2011 United States
Primary
Secondary
Concomitant
Herpes Simplex Hospitalization 5/19/2008 75 Male 198 lb 5/5/2011 Consumer Poland
Primary
Secondary
Concomitant
Pulmonary Infarction Hospitalization 11/10/2009 27 Female 198 lb 5/11/2011 Consumer United States
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/16/2011 Physician Serbia
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 5/16/2011 Physician Serbia
Primary
Secondary
Concomitant
Bone Lesion Other Serious 12/16/2005 61 Male 136 lb 5/19/2011 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 5/3/2011 70 Female 5/20/2011 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 1/1/2002 58 Female 115 lb 5/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Engraft Failure Life Threatening 8/9/2010 Female 33 lb 6/1/2011 Physician Japan
Primary
Concomitant
Adrenal Insufficiency Other Serious 1/1/2000 53 Female 6/1/2011 Other Health Professional United States
Primary
Concomitant
Dehydration Hospitalization 5/10/2011 57 Male 203 lb 6/2/2011 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 7/18/2010 61 Female 110 lb 6/21/2011 Physician Japan
Primary
Secondary
Concomitant
Skin Haemorrhage Other Serious 1/4/2001 64 Female 6/22/2011 Consumer United States
Primary
Secondary
Concomitant
Graft Versus Host Disease Hospitalization 5/25/2010 23 Female 73 lb 6/23/2011 Physician Japan
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Other Serious 3/5/2010 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
Anaemia Of Chronic Disease Other Serious 3/17/2004 56 Female 140 lb 6/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nasal Discomfort Other Serious 1/1/2005 60 Male 6/30/2011 Lawyer United States
Primary
Concomitant
Abscess Bacterial Hospitalization 11/25/2009 61 Male 141 lb 7/18/2011 Physician Japan
Primary
Secondary
Concomitant
Back Pain Hospitalization 1/1/2000 53 Female 7/21/2011 Physician United States
Primary
Concomitant
Pseudomonal Sepsis Death 9/1/2010 52 Male 154 lb 7/22/2011 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Death 3/17/2004 56 Female 140 lb 7/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/10/2010 49 Female 97 lb 8/2/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Death 11/10/2010 49 Female 97 lb 8/3/2011 Physician Japan
Primary
Secondary
Concomitant
Wheelchair User Other Serious 8/1/2005 36 Male 170 lb 8/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 2/11/2009 54 Male 152 lb 8/5/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Life Threatening 1/17/2011 27 Female 95 lb 8/5/2011 Physician Japan
Primary
Concomitant
Insomnia Other Serious 11/23/2010 62 Female 108 lb 8/8/2011 Physician Japan
Primary
Concomitant
Acidosis Hyperchloraemic Hospitalization 12/16/2005 61 Male 136 lb 8/8/2011 Other Health Professional United States
Primary
Concomitant
Muscular Weakness Other Serious 1/1/2005 55 Female 168 lb 8/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 1/1/2002 58 Female 115 lb 8/10/2011 Lawyer United States
Primary
Secondary
Concomitant
Cytomegalovirus Gastroenteritis Other Serious 2/11/2009 54 Male 152 lb 8/11/2011 Physician Japan
Primary
Concomitant
Aspiration Hospitalization 3/12/2011 81 Female 136 lb 8/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Disease Progression Required Intervention Male 8/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Transplant Required Intervention Female 8/17/2011 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data