Fluconazole combined with Levofloxacin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Death 11/30/2004 64 Female 128 lb 1/4/2006 Physician Korea, Republic Of
Primary
Concomitant
International Normalised Ratio Increased 4/30/2004 60 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 10/18/2004 54 9/16/2005 Pharmacist United States
Primary
Concomitant
Vaginal Infection Other Serious 10/12/2005 63 Female 1/18/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 11/3/2005 66 Male 1/16/2006 Physician France
Primary
Secondary
Sepsis Life Threatening 10/8/2004 56 Male 1/26/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 11/3/2005 66 Male 2/1/2006 Physician France
Primary
Secondary
Sepsis Death 11/30/2004 64 Female 128 lb 2/7/2006 Physician Korea, Republic Of
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 12/29/2005 63 Male 2/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Post Procedural Complication Death 34 Male 2/7/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/1/2005 63 Female 2/10/2006 Other Health Professional Japan
Primary
Concomitant
Hemiplegia Death 34 Male 2/16/2006 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 1/1/2003 38 Female 2/13/2006 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/29/2005 63 Male 2/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/17/2006 Female 210 lb 3/8/2006 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 7/1/2005 Male 154 lb 3/31/2006 Physician Germany
Primary
Secondary
Concomitant
Nausea Disability 10/10/2005 40 Male 240 lb 4/6/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 1/1/1998 Male 154 lb 4/17/2006 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/1/2005 63 Female 4/17/2006 Japan
Primary
Concomitant
Rhabdomyolysis Life Threatening 6/13/2005 49 Female 265 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Required Intervention 12/2/2005 60 Male 161 lb 12/29/2005 United States
Primary
Concomitant
Uveitis Other Serious 1/27/2005 Female 5/17/2006 Japan
Primary
Secondary
Concomitant
Alveolitis Allergic Hospitalization 2/15/2006 Male 5/18/2006 Physician Japan
Primary
Secondary
Concomitant
Alveolitis Allergic Hospitalization 2/15/2006 Male 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 3/17/2006 61 Male 6/2/2006 Physician United States
Primary
Secondary
Concomitant
Human Herpesvirus 6 Infection Death 34 Male 5/23/2006 Physician Japan
Primary
Concomitant
Proteinuria Hospitalization 8/11/2003 30 Male 6/14/2006 Japan
Primary
Concomitant
Drug Ineffective Death 4/27/2004 Male 6/30/2006 United States
Primary
Concomitant
Therapy Non-responder Hospitalization 6/6/2006 Female 151 lb 7/4/2006 Pharmacist United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 6/5/2006 62 Male 7/19/2006 Physician Italy
Primary
Secondary
Concomitant
Weight Increased Hospitalization 3/31/2003 63 Female 151 lb 7/24/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/5/2006 62 Male 7/27/2006 Physician Italy
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/20/2005 62 Male 8/11/2006 Pharmacist United States
Primary
Secondary
Venoocclusive Liver Disease Life Threatening 9/13/2004 56 Female 190 lb 9/8/2006 United States
Primary
Concomitant
Febrile Neutropenia Other Serious 5/15/2006 83 Female 9/13/2006 United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 8/23/2006 Male 154 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/16/2006 37 Male 9/21/2006 Japan
Primary
Secondary
Concomitant
Mouth Haemorrhage Death 8/30/2006 76 Female 9/22/2006 Germany
Primary
Concomitant
Venoocclusive Liver Disease Required Intervention 55 Female 10/5/2006 Germany
Primary
Secondary
Concomitant
Nystagmus Other Serious 4/2/2006 75 Female 10/18/2006 Other Health Professional Japan
Primary
Concomitant
Somnolence Death 7/11/2006 Male 146 lb 10/20/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/10/2006 63 Male 10/30/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Death 5/14/2002 65 Female 11/8/2006 Italy
Primary
Secondary
Concomitant
Septic Shock Death 75 Male 11/21/2006 Greece
Primary
Secondary
White Blood Cell Count Decreased Other Serious 11/21/2005 37 Male 11/22/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Wound Drainage Other Serious 12/1/2000 56 Female 259 lb 12/7/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/3/2003 Male 1/3/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/25/2006 Female 1/3/2007 United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 12/1/2000 56 Female 259 lb 1/12/2007 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 7/3/2006 71 Male 1/12/2007 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/28/2006 67 Female 1/25/2007 Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 2/26/2003 Male 230 lb 2/6/2007 Pharmacist United States
Primary
Concomitant
Interacting
Wound Drainage Other Serious 12/1/2000 56 Female 259 lb 2/23/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Fungal Other Serious 80 Male 3/5/2007 Physician Spain
Primary
Secondary
Concomitant
Pco2 Abnormal Other Serious 2/1/2007 Female 250 lb 3/2/2007 Other Health Professional United States
Primary
Concomitant
Neutropenia Other Serious 5/15/2006 83 Female 2/26/2007 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 80 Male 3/12/2007 Physician Spain
Primary
Secondary
Concomitant
Drug Level Decreased Other Serious 31 Female 3/19/2007
Primary
Concomitant
Interacting
Systemic Lupus Erythematosus Other Serious 31 Female 3/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 7/3/2006 71 Male 3/15/2007 Japan
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 3/6/2007 45 Male 165 lb 3/19/2007 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 5/15/2006 83 Female 3/19/2007 Japan
Primary
Secondary
Concomitant
Hepatitis B Virus Other Serious 2/23/2007 63 Female 132 lb 4/6/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting 49 Male 157 lb 4/24/2007 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 5/15/2006 83 Female 4/13/2007 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/15/2006 51 Male 5/11/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/15/2006 52 Male 5/18/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2005 Female 231 lb 6/12/2007 United States
Primary
Concomitant
Interacting
Stomatitis Hospitalization 5/22/2007 65 Female 130 lb 6/18/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 5/15/2006 83 Female 6/21/2007 United States
Primary
Secondary
Concomitant
Bursitis Hospitalization 5/14/2007 Female 121 lb 6/27/2007 Italy
Primary
Concomitant
Tachycardia Other Serious 12/15/2006 37 Male 108 lb 12/15/2006 United States
Primary
Secondary
Concomitant
Bursitis Hospitalization 5/14/2007 Female 121 lb 7/12/2007 Italy
Primary
Concomitant
Rash Hospitalization 4/13/2007 63 Male 181 lb 4/25/2007 Pharmacist United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 53 Male 7/26/2007 Switzerland
Primary
Concomitant
Toxic Shock Syndrome Death 10/28/2004 84 Male 8/2/2007 Physician Japan
Primary
Concomitant
Bursitis Infective Hospitalization 5/14/2007 Female 121 lb 8/10/2007 Italy
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/9/2006 67 Female 8/10/2007 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/27/2007 Male 146 lb 8/14/2007 Italy
Primary
Concomitant
Hepatotoxicity Other Serious 38 Female 8/3/2007 Germany
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 6/5/2007 58 Male 145 lb 8/22/2007 Pharmacist United States
Primary
Concomitant
Sinus Bradycardia Life Threatening 4/12/2007 Female 127 lb 4/16/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/3/2003 Male 8/29/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious 73 Male 8/30/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 12/5/2006 70 Female 9/6/2007 Physician Japan
Primary
Secondary
Concomitant
Peritonitis Hospitalization 6/30/2007 70 Female 153 lb 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 85 Male 9/17/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 75 Male 9/17/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 72 Female 9/17/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 78 Male 9/17/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 72 Male 9/17/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 66 Male 9/17/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Death 75 Male 9/17/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 78 Male 9/17/2007 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 70 Female 9/17/2007 Japan
Primary
Secondary
Concomitant
Hypotension Death 3/20/2007 78 Female 9/24/2007 Pharmacist United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/24/2007 51 Male 9/24/2007 United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 54 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 61 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Death 79 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/19/2006 37 Female 135 lb 10/4/2007 Physician United States
Primary
Concomitant
Stomatitis Other Serious 7/24/2007 51 Male 11/2/2007 Japan
Primary
Secondary
Concomitant
Rash Other Serious 2/3/2007 60 Male 132 lb 11/5/2007 Physician Japan
Primary
Concomitant
Sepsis Other Serious 2/26/2007 45 Female 380 lb 11/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 11/20/2007 Germany
Primary
Concomitant
Escherichia Sepsis Death Unknown 11/27/2007 Consumer United States
Primary
Secondary
Concomitant
Escherichia Sepsis Death Unknown 11/27/2007 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Fungal Other Serious Unknown 11/27/2007 Consumer United States
Primary
Secondary
Concomitant
Klebsiella Bacteraemia Other Serious Unknown 11/27/2007 Consumer United States
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Other Serious Unknown 11/27/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious Unknown 11/27/2007 Consumer United States
Primary
Secondary
Concomitant
Enterocolitis Hospitalization Unknown 11/27/2007 United States
Primary
Secondary
Concomitant
Enterocolitis Hospitalization Unknown 11/27/2007 United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/24/2007 51 Male 12/13/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 12/4/2007 72 Female 191 lb 12/24/2007 United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 36 Female 265 lb 1/8/2008
Primary
Secondary
Concomitant
Abdominal Pain Required Intervention 12/3/2007 42 Male 12/11/2007 Pharmacist United States
Primary
Concomitant
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 2/15/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 2/23/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Death 11/4/2004 Female 3/14/2008 Germany
Primary
Secondary
Concomitant
Pallor Hospitalization 1/4/2008 Female 189 lb 3/14/2008 Pharmacist United States
Primary
Concomitant
Sinusitis Hospitalization 4/23/2007 9 Female 54 lb 4/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting 49 Male 157 lb 4/17/2008 Consumer United States
Primary
Secondary
Concomitant
Swollen Tongue Death 11/4/2004 Female 4/18/2008 Germany
Primary
Secondary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 4/16/2008 Germany
Primary
Concomitant
Loss Of Consciousness Life Threatening 3/28/2008 27 Male 139 lb 4/28/2008 Physician Japan
Primary
Concomitant
Herpes Simplex Hospitalization 3/23/2008 Female 101 lb 5/5/2008 Physician United States
Primary
Concomitant
Septic Shock Life Threatening 8/6/2007 53 Male 5/9/2008 Germany
Primary
Concomitant
Urinary Tract Infection Hospitalization 10/1/2007 86 Female 5/10/2008 Pharmacist United States
Primary
Secondary
Fungal Infection Hospitalization 1/8/2008 Female 123 lb 5/21/2008 Physician Belgium
Primary
Secondary
Concomitant
Tremor Life Threatening 5/15/2008 Male 207 lb 5/23/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/19/2007 Male 165 lb 6/26/2008 Physician Japan
Primary
Secondary
Concomitant
Bone Pain Other Serious 1/10/2008 30 Male 7/14/2008 Physician Belgium
Primary
Concomitant
Somnolence Life Threatening 73 Female 7/28/2008 Physician United States
Primary
Secondary
Concomitant
Bone Pain Other Serious 1/10/2008 30 Male 8/7/2008 Physician Belgium
Primary
Concomitant
Quadriplegia Life Threatening 63 Male 8/11/2008 Other Health Professional United States
Primary
Concomitant
Serotonin Syndrome Other Serious 73 Female 8/13/2008 United States
Primary
Concomitant
Interacting
Serotonin Syndrome Life Threatening 73 Female 8/21/2008 United States
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 8/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Bone Pain Other Serious 1/10/2008 30 Male 8/29/2008 Physician Belgium
Primary
Concomitant
Metabolic Acidosis Hospitalization 10/28/2007 Female 143 lb 9/2/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/20/2008 Male 218 lb 9/2/2008 United States
Primary
Concomitant
Urine Abnormality Hospitalization 8/13/2008 78 Male 9/5/2008 Other Health Professional United States
Primary
Concomitant
Bone Pain Other Serious 1/10/2008 30 Male 9/11/2008 Physician Belgium
Primary
Concomitant
Metabolic Acidosis Life Threatening 10/28/2007 Female 143 lb 9/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Somnolence Life Threatening 73 Female 9/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Fungaemia Other Serious 57 Female 9/26/2008 Physician Japan
Primary
Concomitant
Serotonin Syndrome Other Serious 73 Female 9/26/2008 United States
Primary
Concomitant
Interacting

Drug Data