Flolan combined with Sildenafil Citrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Troponin I Increased Other Serious 11/3/2005 35 Male 170 lb 2/6/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Required Intervention 10/12/2004 14 Female 108 lb 3/9/2006 Physician United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/26/2006 35 Female 220 lb 3/15/2006 Physician Canada
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/26/2006 35 Female 220 lb 3/15/2006 Physician Canada
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 4/8/2005 33 Female 126 lb 3/22/2006 Consumer United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/26/2006 35 Female 220 lb 3/16/2006 Physician Canada
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 54 Male 3/24/2006 Physician Belgium
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/26/2006 35 Female 220 lb 3/24/2006 Physician Canada
Primary
Secondary
Concomitant
Sudden Death Other Serious 4/7/2006 40 Female 4/19/2006 Physician France
Primary
Concomitant
Sudden Death Other Serious 4/7/2006 40 Female 4/27/2006 Physician France
Primary
Concomitant
Sudden Death Other Serious 4/7/2006 40 Female 4/26/2006 Physician France
Primary
Concomitant
Thrombosis Other Serious 3/3/2005 70 Female 4/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 2/26/2006 35 Female 220 lb 5/18/2006 Physician Canada
Primary
Secondary
Concomitant
Sudden Death Other Serious 4/7/2006 40 Female 5/15/2006 Physician France
Primary
Concomitant
Thrombosis Other Serious 3/3/2005 70 Female 5/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 11/1/2005 41 Male 289 lb 5/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/7/2004 43 Female 108 lb 7/20/2006 Physician Japan
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 7/31/2004 26 Female 149 lb 7/24/2006 Physician Japan
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 7/8/2004 45 Female 231 lb 8/15/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 2/12/2005 34 Female 158 lb 8/22/2006 Consumer United States
Primary
Secondary
Concomitant
Vulval Disorder Hospitalization 8/2/2006 29 Female 108 lb 8/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Muscle Twitching Hospitalization 1/31/2006 34 Female 114 lb 8/23/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 11/1/2005 41 Male 8/23/2006 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/8/2004 47 Female 118 lb 8/28/2006 Physician Canada
Primary
Secondary
Concomitant
Urticaria Hospitalization 8/2/2006 29 Female 108 lb 8/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vaginal Lesion Hospitalization 8/2/2006 29 Female 108 lb 8/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Life Threatening 8/30/2001 13 Male 9/27/2006 Physician Japan
Primary
Secondary
Concomitant
Syncope Life Threatening 8/30/2001 13 Male 10/3/2006 Physician Japan
Primary
Secondary
Concomitant
Syncope Life Threatening 8/30/2001 13 Male 10/16/2006 Physician Japan
Primary
Secondary
Concomitant
Syncope Life Threatening 8/30/2001 13 Male 10/19/2006 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 10/23/2006 70 Female 11/17/2006 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 11/4/2006 39 Female 121 lb 11/20/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 7/31/2004 26 Female 149 lb 11/30/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 12/4/2004 44 Female 108 lb 11/30/2006 Physician Japan
Primary
Secondary
Concomitant
Off Label Use 41 Female 115 lb 11/30/2006 Physician Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 8/8/2006 64 Female 1/30/2007 Physician United States
Primary
Secondary
Concomitant
Embolism Other Serious 1/25/2007 54 Male 164 lb 2/6/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint 2/14/2007 62 Male 194 lb 2/26/2007 Consumer United States
Primary
Concomitant
Red Blood Cell Schistocytes Present Other Serious 8/8/2006 64 Female 2/23/2007 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 12/2/2006 64 Male 181 lb 3/2/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2007 62 Male 194 lb 3/2/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/14/2007 37 Male 209 lb 3/7/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/22/2007 43 Female 149 lb 3/7/2007 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 12/6/2006 64 Male 181 lb 3/12/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2007 62 Male 194 lb 3/12/2007 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/22/2007 43 Female 149 lb 3/12/2007 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/25/2007 43 Male 210 lb 3/15/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/25/2007 43 Male 210 lb 3/28/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 12/6/2006 64 Male 181 lb 3/29/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/22/2007 43 Female 149 lb 3/29/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 3/17/2007 68 Female 130 lb 3/30/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2007 62 Male 194 lb 4/3/2007 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 9/21/2006 63 Female 145 lb 4/10/2007 Consumer United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2007 62 Male 194 lb 4/17/2007 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/14/2007 37 Male 209 lb 4/17/2007 Consumer United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 1/1/2006 Female 196 lb 4/25/2007 Physician France
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/25/2007 43 Male 210 lb 5/8/2007 Consumer United States
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 8/2/2006 29 Female 5/8/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/17/2007 68 Female 96 lb 5/23/2007 Consumer United States
Primary
Concomitant
Headache Other Serious 1/1/2006 55 Male 173 lb 3/22/2007 Physician United States
Primary
Concomitant
Disease Progression Death 7 Female 44 lb 6/19/2007 Pharmacist Ireland
Primary
Concomitant
Disease Progression Death 7 Female 44 lb 6/27/2007 Pharmacist Ireland
Primary
Concomitant
Disease Progression Death 7 Female 44 lb 7/2/2007 Pharmacist Ireland
Primary
Concomitant
Pleural Effusion Hospitalization 4/4/2007 Female 148 lb 8/10/2007 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 12/6/2005 24 Female 10/25/2007 Physician Japan
Primary
Concomitant
Retinal Exudates Other Serious 9/13/2007 43 Female 97 lb 11/27/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 12/6/2005 24 Female 12/3/2007 Physician Japan
Primary
Concomitant
Weight Increased Hospitalization 12/6/2005 24 Female 1/11/2008 Physician Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 9/21/2006 63 Female 145 lb 2/12/2008 Consumer United States
Primary
Secondary
Concomitant
Rash Other Serious 3/3/2005 Female 3/5/2008 United States
Primary
Concomitant
Interacting
Rash Female 96 lb 5/30/2008 Consumer United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 1/19/2006 39 Female 6/11/2008 Physician Japan
Primary
Secondary
Concomitant
Ventricular Dysfunction Required Intervention 10/12/2004 14 Female 108 lb 6/26/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 10/5/2005 Female 104 lb 7/2/2008 United States
Primary
Concomitant
Interacting
Scleroderma Other Serious 8/8/2008 Female 142 lb 9/16/2008 Consumer United States
Primary
Concomitant
Right Ventricular Failure Hospitalization Female 179 lb 9/25/2008 Physician United States
Primary
Concomitant
Tachycardia Hospitalization Female 9/29/2008 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Death Death Male 12/5/2008 Physician Australia
Primary
Concomitant
Catheter Related Infection Other Serious 11/11/2008 Female 255 lb 12/12/2008 Other Health Professional United States
Primary
Concomitant
Hepatic Failure Death 5/5/2008 12/17/2008 Physician Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/29/2008 Female 135 lb 12/17/2008 Other Health Professional United States
Primary
Concomitant
Syncope Death 7/24/2008 Male 12/22/2008 Other Health Professional Australia
Primary
Concomitant
Weight Increased Hospitalization 12/6/2005 24 Female 12/23/2008 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 10/20/2008 12/24/2008 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 6/1/2008 1/5/2009 Physician Japan
Primary
Concomitant
Vomiting Death 8/26/2008 29 Female 133 lb 12/17/2008 Physician United States
Primary
Concomitant
Liver Disorder Hospitalization 6/1/2008 2/9/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/6/2004 Female 231 lb 3/19/2009 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/29/2008 Female 135 lb 3/23/2009 Other Health Professional United States
Primary
Concomitant
Electrocardiogram Change Hospitalization 3/31/2008 Female 121 lb 4/20/2009 Other Health Professional United States
Primary
Concomitant
Convulsion Other Serious 4/7/2006 4/21/2009 Physician France
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 7/6/2004 Female 231 lb 5/21/2009 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Life Threatening 7/21/2004 Female 148 lb 5/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/6/2004 Female 231 lb 5/26/2009 Physician United States
Primary
Concomitant
Suicide Attempt Life Threatening 9/3/2006 56 5/28/2009 Other Health Professional Netherlands
Primary
Concomitant
Thrombocytopenia Hospitalization 7/6/2004 Female 231 lb 5/29/2009 Physician United States
Primary
Concomitant
Convulsion Other Serious 4/7/2006 40 5/29/2009 Physician France
Primary
Concomitant
Pancreatitis Acute Hospitalization 10/28/2004 64 6/9/2009 Other Health Professional Belgium
Primary
Concomitant
Central Line Infection Other Serious 6/12/2006 Female 183 lb 6/12/2009 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/29/2008 Female 135 lb 6/12/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Life Threatening 7/21/2004 Female 148 lb 6/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization Female 123 lb 7/6/2009 Physician United States
Primary
Concomitant
Death Death 7/17/2009 Physician Japan
Primary
Concomitant
Hypotension Other Serious 19 Female 7/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Persistent Foetal Circulation Death 7/6/2009 0 8/5/2009 Other Health Professional Japan
Primary
Concomitant
Dyspnoea Other Serious 9/20/2008 52 8/17/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Renal Failure Life Threatening 5/25/2009 65 8/18/2009 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 4/29/2008 29 9/2/2009 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 4/29/2008 29 9/15/2009 Physician Japan
Primary
Concomitant
Pulmonary Hypertension Other Serious 10/20/2008 43 9/25/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 10/20/2008 43 10/9/2009 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 10/20/2008 43 10/14/2009 Physician Japan
Primary
Secondary
Concomitant
Restlessness Hospitalization 3/4/2009 0 Male 8 lb 11/19/2009 Physician Japan
Primary
Concomitant
Restlessness Hospitalization 3/4/2009 0 Male 8 lb 11/24/2009 Physician Japan
Primary
Concomitant
Restlessness Hospitalization 3/4/2009 0 Male 8 lb 12/23/2009 Physician Japan
Primary
Secondary
Concomitant
Death Death 12/13/2009 1 Female 10 lb 12/28/2009 Physician Japan
Primary
Concomitant
Death Death 75 Female 101 lb 12/29/2009 Physician Japan
Primary
Concomitant
Restlessness Hospitalization 3/4/2009 0 Male 6 lb 12/29/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 11/1/2007 56 Female 12/22/2009 Physician United States
Primary
Concomitant
Restlessness Other Serious 3/4/2009 Male 6 lb 1/5/2010 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Death 75 Female 101 lb 12/31/2009 Physician Japan
Primary
Concomitant
Hypotension Other Serious 1/1/2008 34 Female 111 lb 1/20/2010 Physician Japan
Primary
Concomitant
Restlessness Other Serious 3/4/2009 0 Male 6 lb 1/25/2010 Physician Japan
Primary
Secondary
Concomitant
Death Death 12/20/2009 45 Female 86 lb 2/16/2010 Physician Japan
Primary
Concomitant
Dyspnoea Other Serious 9/20/2008 52 Female 101 lb 2/16/2010 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2007 56 Female 2/10/2010 Physician United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 6/23/2005 36 Female 102 lb 2/19/2010 Japan
Primary
Secondary
Concomitant
Pulmonary Veno-occlusive Disease Other Serious 7/31/2008 32 Male 129 lb 2/23/2010 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 11/1/2009 49 Female 213 lb 2/17/2010 Physician Canada
Primary
Concomitant
Right Ventricular Failure Other Serious 12/20/2009 45 Female 86 lb 3/2/2010 Physician Japan
Primary
Concomitant
Death Death 9/22/2009 41 Male 108 lb 3/4/2010 Physician Japan
Primary
Concomitant
Cardiac Failure Death 12/13/2009 1 Female 10 lb 3/4/2010 Physician Japan
Primary
Concomitant
Tachycardia Hospitalization 3/2/2010 0 Male 3/24/2010 Physician Japan
Primary
Concomitant
Tachycardia Hospitalization 3/2/2010 0 Male 4/6/2010 Physician Japan
Primary
Concomitant
Hypotension Other Serious 7/10/2008 34 Female 111 lb 4/9/2010 Physician Japan
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 9/20/2008 52 Female 101 lb 4/27/2010 Japan
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 9/20/2008 52 Female 101 lb 5/19/2010 Japan
Primary
Secondary
Concomitant
Death Death 2/26/2010 17 Female 74 lb 6/1/2010 Physician Japan
Primary
Concomitant
Cardiac Failure Death 17 Female 74 lb 6/11/2010 Physician Japan
Primary
Concomitant
Sepsis Life Threatening 3/7/2009 0 Female 4 lb 7/12/2010 Physician Japan
Primary
Concomitant
Pulmonary Hypertension Other Serious 41 Male 108 lb 8/11/2010 Physician Japan
Primary
Concomitant
Weight Decreased Other Serious 3/5/2004 17 Male 8/24/2010 Physician Canada
Primary
Concomitant
Death Death 8/13/2010 17 Female 93 lb 9/21/2010 Physician Japan
Primary
Concomitant
Sepsis Life Threatening 2/23/2009 0 Female 4 lb 10/19/2010 Physician Japan
Primary
Secondary
Concomitant
Death Death 23 Male 112 lb 10/28/2010 Physician Japan
Primary
Concomitant
Pregnancy Other Serious 1/30/2008 29 Female 10/28/2010 Physician Canada
Primary
Concomitant
Ventricular Fibrillation Other Serious 7/13/2008 14 Female 79 lb 11/3/2010 Physician Japan
Primary
Secondary
Concomitant
Death Death 8/13/2010 17 Female 93 lb 11/4/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 6/1/2010 67 Male 11/5/2010 Other Health Professional France
Primary
Secondary
Concomitant
Pneumothorax Other Serious 3/5/2010 0 Male 57 lb 11/12/2010 Physician Japan
Primary
Secondary
Concomitant

Drug Data