Filgrastim combined with Itraconazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rash Hospitalization 1/12/2006 Female 117 lb 2/15/2006 Physician Portugal
Primary
Concomitant
Proteinuria Hospitalization 12/2/2007 72 Male 216 lb 4/23/2008 Physician United Kingdom
Primary
Concomitant
Septic Shock Life Threatening 2/14/2008 Male 134 lb 4/30/2008 Physician Japan
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 69 Male 3/20/2009 Other Health Professional Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 5/13/2009 43 Male 6/26/2009 Physician United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 3/30/2009 59 Male 1/29/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2009 Male 5/5/2010 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 6/24/2009 15 Male 126 lb 11/23/2010 Physician Japan
Primary
Concomitant
Subdural Haematoma 5/3/2010 69 Female 110 lb 11/23/2010 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Death 4/4/2009 55 Male 165 lb 11/29/2010 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Death 1/27/2010 55 Female 128 lb 11/29/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 6/12/2010 12/1/2010 Consumer Japan
Primary
Concomitant
Urinary Tract Infection Bacterial Life Threatening 3/1/2010 74 Female 119 lb 12/9/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/29/2010 49 Male 110 lb 12/13/2010 Physician Japan
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 3/28/2010 69 Male 110 lb 12/20/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 12/12/2009 76 Male 119 lb 12/23/2010 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 8/11/2010 77 Male 110 lb 12/23/2010 Physician United States
Primary
Concomitant
Pancytopenia Hospitalization 8/11/2010 77 Male 110 lb 12/29/2010 Physician Italy
Primary
Concomitant
Urinary Tract Infection Bacterial Death 3/25/2010 58 Male 150 lb 12/29/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 12/12/2009 76 Male 119 lb 12/29/2010 Physician Japan
Primary
Concomitant
Pyrexia Death 3/25/2010 58 Male 150 lb 12/29/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/6/2011 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 7/1/2009 48 Female 115 lb 1/6/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 10/23/2009 62 Male 130 lb 1/7/2011 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Death 8/11/2010 24 Male 141 lb 1/7/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Test Positive Death 5/1/2010 54 Female 119 lb 1/10/2011 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 9/26/2010 67 Female 97 lb 1/10/2011 Physician Japan
Primary
Concomitant
Blood Pressure Increased Other Serious 8/9/2009 48 Female 115 lb 1/10/2011 Physician Japan
Primary
Secondary
Concomitant
Cytomegalovirus Test Positive Hospitalization 5/1/2010 54 Female 119 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
Multi-organ Failure Death 10/22/2010 54 Male 176 lb 1/21/2011 Physician Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/10/2009 18 Male 137 lb 1/24/2011 Physician Japan
Primary
Concomitant
Thrombocytopenia Death 1/19/2011 57 Male 2/10/2011 Physician Japan
Primary
Concomitant
Fungal Infection Hospitalization 6/24/2009 15 Male 126 lb 2/14/2011 Consumer Japan
Primary
Concomitant
Sepsis Other Serious 9/10/2009 18 Male 137 lb 2/15/2011 Physician Japan
Primary
Concomitant
Haemodialysis Death 7/10/2010 60 Male 163 lb 2/18/2011 Physician Japan
Primary
Concomitant
Infusion Related Reaction Life Threatening 8/18/2010 46 Female 2/18/2011 Physician Czech Republic
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 7/8/2009 45 Male 1/26/2011 Consumer United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/2/2010 3/3/2011 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 10/24/2010 19 Male 115 lb 3/10/2011 Physician Japan
Primary
Concomitant
Thrombocytopenia Death 3/14/2011 4 Male 33 lb 3/24/2011 Consumer Mexico
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 7/7/2010 64 Male 117 lb 3/28/2011 Physician Japan
Primary
Concomitant
Red Blood Cell Count Decreased Death 1/19/2011 57 Male 4/6/2011 Physician Japan
Primary
Concomitant
Multi-organ Failure Hospitalization 3/14/2011 4 Male 33 lb 4/7/2011 Physician Mexico
Primary
Secondary
Concomitant
Interleukin-2 Receptor Increased Hospitalization 12/24/2010 76 Male 5/4/2011 Physician Japan
Primary
Concomitant
Petechiae Other Serious 1/29/2010 49 Male 110 lb 5/20/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 6/27/2010 65 Female 112 lb 6/16/2011 Physician Japan
Primary
Concomitant
Convulsion Hospitalization 5/5/2009 18 Female 108 lb 6/28/2011 Physician Japan
Primary
Concomitant
Aplastic Anaemia Death 10/4/2010 53 Female 121 lb 6/29/2011 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 7/21/2010 7/5/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/6/2011 71 Male 132 lb 7/12/2011 Physician Korea, Republic Of
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 9/26/2010 67 Female 97 lb 7/15/2011 Physician Japan
Primary
Secondary
Concomitant
Face Oedema Other Serious 6/27/2011 31 Male 146 lb 7/18/2011 Physician Spain
Primary
Concomitant
Febrile Neutropenia 6/27/2010 65 Female 112 lb 8/14/2011 Physician Japan
Primary
Concomitant
Neutropenia Hospitalization 4/6/2011 71 Male 132 lb 8/24/2011 Physician Korea, Republic Of
Primary
Concomitant
Pyrexia Hospitalization 11/19/2010 26 Female 115 lb 8/26/2011 Physician Japan
Primary
Concomitant
Herpes Pharyngitis Hospitalization 2/7/2011 54 Female 97 lb 9/1/2011 Physician Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 12/20/2010 76 Male 9/16/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 2/17/2011 46 Female 97 lb 9/21/2011 Physician Japan
Primary
Concomitant
Somnolence Hospitalization 3/30/2009 59 Male 9/27/2011 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 3/11/2009 23 Female 97 lb 9/29/2011 Physician Japan
Primary
Concomitant
Death Life Threatening 8/7/2010 Female 10/6/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Hepatomegaly Hospitalization 5/10/2010 56 Male 132 lb 11/22/2011 Physician Japan
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Death 12/20/2010 76 Male 11/22/2011 Physician Japan
Primary
Concomitant
Fall Other Serious 6/12/2010 70 Male 154 lb 11/23/2011 Physician Japan
Primary
Concomitant
Multi-organ Failure Hospitalization 6/24/2009 15 Male 126 lb 11/23/2011 Physician Japan
Primary
Concomitant
Thyroid Cancer Other Serious 3/8/2010 74 Female 99 lb 11/25/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 8/7/2010 Female 16 lb 11/29/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Acute Graft Versus Host Disease In Skin Other Serious 3/8/2010 74 Female 99 lb 12/1/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 11/24/2010 49 Male 134 lb 12/7/2011 Physician Japan
Primary
Concomitant
Hypoalbuminaemia Other Serious 5/24/2011 50 Male 128 lb 12/7/2011 Physician Japan
Primary
Concomitant
Escherichia Sepsis Hospitalization 2/16/2011 68 Male 137 lb 12/7/2011 Physician Japan
Primary
Concomitant
Venoocclusive Liver Disease Death 2/7/2009 57 Male 139 lb 12/14/2011 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 11/24/2010 36 Male 134 lb 12/19/2011 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 1/27/2010 55 Female 128 lb 12/20/2011 Physician Japan
Primary
Concomitant
Epstein-barr Virus Associated Lymphoproliferative Disorder Death 9/23/2011 66 Female 139 lb 12/21/2011 Physician Japan
Primary
Concomitant
Cytomegalovirus Test Positive Death 1/23/2010 66 Male 130 lb 12/30/2011 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 4/11/2011 52 Female 126 lb 1/3/2012 Physician Japan
Primary
Concomitant
Anaemia Other Serious 12/20/2010 76 Male 1/4/2012 Physician Japan
Primary
Concomitant
Abdominal Infection Other Serious 10/11/2011 57 Female 79 lb 1/23/2012 Physician Japan
Primary
Concomitant
Transplant Rejection Other Serious 8 Male 1/25/2012 Other Health Professional China
Primary
Concomitant
Transplant Rejection Other Serious 23 Male 1/25/2012 Other Health Professional China
Primary
Concomitant
Transplant Rejection Other Serious 61 Female 1/25/2012 Other Health Professional China
Primary
Concomitant
Transplant Rejection Other Serious 13 Female 1/25/2012 Other Health Professional China
Primary
Concomitant
Febrile Neutropenia Other Serious 12 Female 1/25/2012 Other Health Professional China
Primary
Concomitant
Febrile Neutropenia Other Serious 21 Male 1/25/2012 Other Health Professional China
Primary
Concomitant
Transplant Rejection Other Serious 20 Male 1/25/2012 Other Health Professional China
Primary
Concomitant
Transplant Rejection Other Serious 6 Female 1/25/2012 Other Health Professional China
Primary
Concomitant
Febrile Neutropenia Other Serious 7 Female 1/25/2012 Other Health Professional China
Primary
Concomitant
Transplant Rejection Other Serious 53 Male 1/25/2012 Other Health Professional China
Primary
Concomitant
Febrile Neutropenia Other Serious 10 Male 1/25/2012 Other Health Professional China
Primary
Concomitant
Transplant Rejection Other Serious 16 Male 1/25/2012 Other Health Professional China
Primary
Concomitant
Transplant Rejection Other Serious 17 Male 1/27/2012 Other Health Professional China
Primary
Concomitant
Transplant Rejection Other Serious 30 Male 1/27/2012 Other Health Professional China
Primary
Concomitant
Transplant Rejection Other Serious 21 Male 1/27/2012 Other Health Professional China
Primary
Concomitant
Venoocclusive Liver Disease Death 2/7/2009 57 Male 139 lb 2/7/2012 Physician Japan
Primary
Concomitant
Post Transplant Lymphoproliferative Disorder Death 3/6/2009 9 Male 49 lb 2/10/2012 Physician Japan
Primary
Concomitant
Abdominal Pain Upper Death 4/2/2009 55 Male 165 lb 2/21/2012 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease In Skin Death 3/6/2009 9 Male 49 lb 3/9/2012 Physician Japan
Primary
Concomitant
Acute Lymphocytic Leukaemia Recurrent Death 10/24/2010 19 Male 97 lb 3/16/2012 Physician Japan
Primary
Concomitant
Non-hodgkin's Lymphoma Death 3/28/2010 69 Male 110 lb 3/27/2012 Physician Japan
Primary
Concomitant
Dry Mouth Death 9/26/2010 67 Female 97 lb 4/2/2012 Physician Japan
Primary
Concomitant
Viral Haemorrhagic Cystitis Hospitalization 6 Male 42 lb 4/3/2012 Physician Japan
Primary
Concomitant
Infection Hospitalization 3/31/2012 Female 4/17/2012 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 3/1/2010 4/19/2012 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 3/1/2010 4/19/2012 Physician Japan
Primary
Concomitant
Infection Hospitalization 3/31/2012 44 Female 119 lb 4/26/2012 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 1/27/2010 55 Female 128 lb 5/4/2012 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 4/11/2011 52 Female 126 lb 6/14/2012 Physician Japan
Primary
Concomitant
Drug-induced Liver Injury Hospitalization 12/16/2010 71 Female 187 lb 6/18/2012 Physician Japan
Primary
Concomitant
Oral Herpes Hospitalization 9/6/2011 51 Female 126 lb 7/3/2012 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/17/2010 28 Female 101 lb 7/9/2012 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 7/21/2010 7/9/2012 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 9/10/2009 18 Male 137 lb 7/13/2012 Physician Japan
Primary
Concomitant
Pneumonia Bacterial Other Serious 20 Female 7/14/2012 Other Health Professional China
Primary
Secondary
Concomitant
Transplant Failure Death 20 Female 7/13/2012 Other Health Professional China
Primary
Secondary
Concomitant
Infection Hospitalization 3/31/2012 44 Female 119 lb 7/18/2012 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 6/2/2010 41 Female 123 lb 7/24/2012 Physician Japan
Primary
Concomitant
Abdominal Pain Upper Hospitalization 4/11/2011 52 Female 126 lb 8/6/2012 Physician Japan
Primary
Concomitant
Diplopia Other Serious 6/17/2012 31 Male 122 lb 8/7/2012 Pharmacist United Kingdom
Primary
Concomitant
Drug-induced Liver Injury Hospitalization 12/16/2010 71 Female 187 lb 8/15/2012 Physician Japan
Primary
Concomitant
Capillary Leak Syndrome Hospitalization 8/7/2010 Female 16 lb 8/16/2012 Physician Netherlands
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/16/2010 71 Female 187 lb 8/20/2012 Physician Japan
Primary
Concomitant
Therapeutic Response Decreased Other Serious 4/2/2009 55 Male 165 lb 8/21/2012 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/13/2009 43 Male 107 lb 8/5/2013 Physician Jp
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 3/11/2009 23 Female 97 lb 3/21/2013 Physician Jp
Primary
Concomitant
Thrombotic Microangiopathy Death 5/7/2009 51 Female 93 lb 4/18/2013 Physician Jp
Primary
Concomitant
Therapeutic Response Decreased Death Male 123 lb 1/16/2013 Physician Jp
Primary
Concomitant
Therapeutic Response Decreased Other Serious 4/2/2009 55 Male 165 lb 9/9/2013 Physician Jp
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 9/10/2009 18 Male 137 lb 5/1/2013 Physician Jp
Primary
Concomitant
Respiratory Failure Other Serious 9/23/2011 67 Female 139 lb 12/21/2012 Physician Jp
Primary
Concomitant
Viral Sepsis Other Serious 2/13/2011 72 Male 137 lb 3/29/2013 Physician Jp
Primary
Concomitant
Infection Death 45 Female 141 lb 11/28/2012 Physician Jp
Primary
Concomitant
Pyrexia Other Serious 9/6/2011 52 Female 126 lb 9/4/2012 Physician Jp
Primary
Secondary
Concomitant
Renal Failure Other Serious 8/18/2012 45 Male 176 lb 9/7/2012 Physician Jp
Primary
Concomitant
Venoocclusive Disease Death 9/2012 Female 10/2/2012 Other Health Professional Kr
Primary
Concomitant
Febrile Neutropenia Hospitalization 11/29/2011 42 Female 139 lb 11/20/2012 Physician Jp
Primary
Concomitant
Epstein-barr Virus Infection Congenital Anomaly 10/24/2011 17 Male 132 lb 10/11/2012 Physician Jp
Primary
Concomitant
Pneumonia Fungal Hospitalization 9/15/2009 57 Female 166 lb 12/7/2012 Physician Es
Primary
Secondary
Concomitant
Pyrexia Other Serious 10/4/2011 23 Female 119 lb 2/7/2013 Physician Jp
Primary
Concomitant
White Blood Cell Count Decreased Death 10/8/2012 61 Male 1/18/2013 Consumer De
Primary
Secondary
Concomitant
Urinary Tract Pain Hospitalization 10/4/2012 10 Male 73 lb 3/13/2013 Physician Jp
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/26/2012 55 Male 170 lb 1/16/2013 Physician Jp
Primary
Secondary
Concomitant
Pneumonia Death 8/7/2012 77 Female 110 lb 8/5/2013 Physician Jp
Primary
Concomitant
Generalised Oedema Hospitalization 3/22/2012 55 Female 88 lb 4/12/2013 Physician Jp
Primary
Secondary
Concomitant
Sepsis Death 9/4/2010 Female 110 lb 10/31/2012 Physician Jp
Primary
Concomitant
Pneumonia Death 7/16/2010 71 Male 126 lb 5/15/2013 Physician Jp
Primary
Concomitant
Serum Sickness Hospitalization 7/30/2012 69 Male 117 lb 4/1/2013 Physician Jp
Primary
Concomitant
Oedema Peripheral Hospitalization 8/10/2011 71 Female 123 lb 7/10/2013 Physician Jp
Primary
Concomitant
Pneumocystis Jirovecii Pneumonia Death 8/5/2011 59 Male 152 lb 5/28/2013 Physician Jp
Primary
Concomitant

Drug Data