Fentanyl combined with Sevoflurane

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Procedural Complication Life Threatening 42 Female 1/2/2006 Physician Japan
Primary
Secondary
Ventricular Tachycardia Other Serious 68 Male 1/24/2006 Japan
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Required Intervention 12/7/2005 56 Male 97 lb 1/20/2006 Physician Japan
Primary
Concomitant
Sinus Tachycardia Other Serious 4 Male 30 lb 1/27/2006 Physician United Kingdom
Primary
Concomitant
Rhabdomyolysis Life Threatening 8/16/2005 Male 1/31/2006 Japan
Primary
Concomitant
Renal Impairment Required Intervention 5/25/2005 68 Male 149 lb 3/1/2006 Physician Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 38 Male 220 lb 3/16/2006 Other Health Professional United States
Primary
Concomitant
Mental Status Changes Life Threatening 6/14/2004 49 Female 3/14/2006 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 5/1/2001 31 Male 183 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 91 Male 137 lb 4/21/2006 Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 30 Male 161 lb 4/11/2006 Physician Spain
Primary
Secondary
Concomitant
Hypotension Other Serious 74 Female 110 lb 4/20/2006 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 4/13/2006 52 Male 190 lb 5/10/2006 Consumer United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 8 Male 64 lb 5/12/2006 Physician France
Primary
Concomitant
Wound Haemorrhage Other Serious 35 Female 116 lb 5/23/2006 Physician China
Primary
Secondary
Concomitant
Tachycardia Required Intervention 38 Male 5/22/2006 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Other Serious 67 Male 139 lb 6/8/2006 Japan
Primary
Secondary
Concomitant
Priapism Other Serious 17 Male 6/9/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 67 Female 123 lb 6/9/2006 Other Health Professional Japan
Primary
Concomitant
Hypotension Other Serious 4/20/2005 72 Female 71 lb 7/28/2006 Japan
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 6/7/2006 Female 8/7/2006 Other Health Professional Japan
Primary
Concomitant
Tryptase Increased Other Serious Female 8/9/2006 Physician Ireland
Primary
Concomitant
Vomiting Life Threatening 7/22/2005 65 Male 176 lb 8/4/2006 United Kingdom
Primary
Concomitant
Wound Secretion Other Serious 35 Female 116 lb 9/1/2006 Other Health Professional China
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 6/7/2006 Female 9/18/2006 Other Health Professional Japan
Primary
Concomitant
Ventricular Extrasystoles Life Threatening 8 Male 9/14/2006 Physician France
Primary
Concomitant
Vasodilatation Life Threatening 8/29/2006 60 Male 9/27/2006 Physician Germany
Primary
Concomitant
Tachycardia Other Serious 4 Male 66 lb 9/28/2006 Greece
Primary
Concomitant
Wound Dehiscence Other Serious 35 Female 116 lb 9/28/2006 United States
Primary
Concomitant
Interacting
Unwanted Awareness During Anaesthesia Other Serious 41 Male 146 lb 10/1/2006 Japan
Primary
Concomitant
Hypotonia Other Serious Female 10/13/2006 Consumer Taiwan, Province Of China
Primary
Concomitant
Pyrexia Hospitalization Male 10/19/2006
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 6/7/2006 Female 127 lb 10/23/2006 Other Health Professional Japan
Primary
Concomitant
Acute Myocardial Infarction Other Serious 80 Male 10/30/2006 Japan
Primary
Concomitant
Postoperative Fever Other Serious 3/1/2005 71 Male 137 lb 11/1/2006 Physician Japan
Primary
Concomitant
Brugada Syndrome Other Serious 36 Male 11/17/2006 Japan
Primary
Secondary
Concomitant
Electrocardiogram St Segment Elevation Life Threatening 36 Male 11/9/2006 Other Health Professional Japan
Primary
Secondary
Pulmonary Oedema Other Serious 84 Female 11/17/2006 Japan
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 84 Female 11/21/2006 Japan
Primary
Secondary
Concomitant
Respiratory Depression Death 26 Female 112 lb 11/21/2006
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 28 Female 11/8/2006 Japan
Primary
Concomitant
Red Blood Cell Count Decreased Hospitalization 4/1/2005 67 Male 146 lb 11/28/2006 Japan
Primary
Concomitant
Spinal Column Stenosis Disability 88 Female 141 lb 11/28/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Tracheomalacia Other Serious 66 Female 106 lb 11/17/2006 Physician Japan
Primary
Secondary
Vasodilatation Life Threatening 8/29/2006 60 Male 11/30/2006 Physician Germany
Primary
Concomitant
Vasodilatation Life Threatening 8/29/2006 60 Male 11/30/2006 Physician Germany
Primary
Concomitant
Urticaria Other Serious 5/2/2006 32 Female 12/7/2006 Physician Japan
Primary
Secondary
Concomitant
Sepsis Other Serious 4 Male 66 lb 12/12/2006 Greece
Primary
Concomitant
Sepsis Other Serious Male 66 lb 12/19/2006 Greece
Primary
Concomitant
Ruptured Ectopic Pregnancy Hospitalization 11/26/2006 36 Female 153 lb 12/11/2006 United States
Primary
Secondary
Concomitant
Loss Of Consciousness Required Intervention 24 Male 12/13/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Sinus Tachycardia Required Intervention 3 Female 28 lb 12/14/2006 United States
Primary
Concomitant
Blood Pressure Decreased Required Intervention 5/2/2006 32 Female 1/10/2007 Physician Japan
Primary
Secondary
Pulmonary Oedema Death 45 Female 2/1/2007 Physician Lebanon
Primary
Secondary
Concomitant
Respiratory Depression Death 26 Female 112 lb 1/29/2007 Physician Germany
Primary
Concomitant
Pulmonary Oedema Other Serious 67 Female 93 lb 2/9/2007 Japan
Primary
Concomitant
Blood Bilirubin Increased Other Serious 11/30/2006 53 Male 2/13/2007 Other Health Professional South Africa
Primary
Concomitant
Prothrombin Time Required Intervention 12/7/2005 56 Male 97 lb 2/14/2007 Physician Japan
Primary
Concomitant
Ventricular Hypokinesia Death 45 Female 2/20/2007 Physician Lebanon
Primary
Secondary
Concomitant
Medication Error Other Serious 5 Female 37 lb 2/26/2007 United States
Primary
Concomitant
Interacting
Ventricular Fibrillation Other Serious 77 Male 3/16/2007 Japan
Primary
Concomitant
Tracheostomy 11 Male 3/12/2007 Japan
Primary
Concomitant
Respiratory Depression Other Serious 78 Female 3/26/2007
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 77 Male 3/29/2007 Japan
Primary
Concomitant
Hyperthermia Malignant Other Serious 4/11/2007 Male 159 lb 4/26/2007 Other Health Professional Japan
Primary
Concomitant
Respiratory Depression Other Serious 78 Female 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Hyperbilirubinaemia Hospitalization 11/28/2006 57 Male 115 lb 4/27/2007 Pharmacist Japan
Primary
Concomitant
Post Procedural Complication Hospitalization 73 Female 5/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 12 Male 5/15/2007 Japan
Primary
Concomitant
Drug Interaction Other Serious 4/27/2007 66 Female 5/17/2007 Physician Japan
Primary
Concomitant
Interacting
Visual Acuity Reduced Other Serious 12 Male 5/24/2007 Japan
Primary
Concomitant
Drug Effect Prolonged Other Serious 4/27/2007 66 Female 115 lb 5/29/2007 Physician Japan
Primary
Concomitant
Interacting
Postoperative Fever Life Threatening 3 Male 20 lb 5/29/2007 Physician China
Primary
Secondary
Tongue Oedema Required Intervention 51 Female 139 lb 2/22/2007 Physician United States
Primary
Concomitant
Urticaria Life Threatening 10/13/2006 26 Female 5/24/2007 Finland
Primary
Concomitant
Dystonia Other Serious 34 Female 6/6/2007 Australia
Primary
Secondary
Interacting
Dystonia Other Serious 34 Female 6/7/2007 Australia
Primary
Secondary
Interacting
Thrombocytopenia Death 7/17/2006 5 Female 44 lb 6/10/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Death 2 Male 29 lb 6/19/2007 Japan
Primary
Secondary
Torsade De Pointes Other Serious 62 Female 6/19/2007 Japan
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 50 Female 6/19/2007 Japan
Primary
Secondary
Concomitant
Myotonia Other Serious 55 Female 132 lb 6/22/2007 United Kingdom
Primary
Concomitant
Interacting
Myotonia Hospitalization 55 Female 6/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 7/1/2005 55 Female 132 lb 6/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 62 Female 6/27/2007 Japan
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 50 Female 6/27/2007 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Death 2 Male 29 lb 6/27/2007 Japan
Primary
Secondary
Pulmonary Arterial Pressure Increased Other Serious 21 Female 6/29/2007 Other Health Professional Japan
Primary
Concomitant
Myotonia Other Serious 55 Female 132 lb 7/6/2007 United Kingdom
Primary
Concomitant
Interacting
Myotonia Hospitalization 7/1/2005 55 Female 132 lb 7/9/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interacting
Unresponsive To Stimuli Other Serious 2 Male 30 lb 7/13/2007 Physician United States
Primary
Concomitant
Myotonia Hospitalization 12/1/2006 55 Female 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Vision Blurred Hospitalization 15 Male 152 lb 7/27/2007
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 12/1/2006 55 Female 132 lb 8/1/2007 United Kingdom
Primary
Concomitant
Interacting
Sinus Tachycardia Hospitalization 55 Female 132 lb 8/1/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Visual Acuity Reduced Other Serious 10/24/2000 12 Male 82 lb 8/2/2007 Japan
Primary
Secondary
Visual Acuity Reduced Other Serious 10/24/2000 12 Male 82 lb 8/2/2007 Japan
Primary
Secondary
Unwanted Awareness During Anaesthesia Other Serious 71 Male 126 lb 8/3/2007 Japan
Primary
Concomitant
Sinus Tachycardia Hospitalization 12/1/2006 55 Female 132 lb 8/8/2007 United Kingdom
Primary
Concomitant
Interacting
Sinus Tachycardia Hospitalization 12/1/2006 55 Female 132 lb 8/21/2007 United Kingdom
Primary
Concomitant
Interacting
Unwanted Awareness During Anaesthesia Other Serious 71 Male 123 lb 8/24/2007 Japan
Primary
Concomitant
Psychotic Disorder Hospitalization 8/1/2007 69 Male 8/27/2007 Consumer Germany
Primary
Secondary
Ventricular Fibrillation Other Serious 1 Female 13 lb 8/27/2007 United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 10/18/2006 12 Male 82 lb 8/30/2007 Japan
Primary
Secondary
Respiratory Arrest Life Threatening 6/13/2007 8/30/2007 Consumer United States
Primary
Secondary
Concomitant
Myotonia Other Serious 7/1/2005 55 Female 132 lb 9/6/2007 United Kingdom
Primary
Concomitant
Interacting
Myotonia Hospitalization 7/1/2005 55 Female 132 lb 9/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Myoclonic Epilepsy Hospitalization 3/5/2007 36 Female 9/10/2007 Australia
Primary
Secondary
Myotonia Hospitalization 55 Female 9/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 55 Female 132 lb 9/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Life Threatening 6/13/2007 9/18/2007 Physician United States
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 12/1/2006 55 Female 132 lb 9/18/2007 United Kingdom
Primary
Concomitant
Interacting
Sinus Tachycardia Hospitalization 7/1/2005 55 Female 132 lb 9/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myotonia Other Serious 7/1/2005 55 Female 132 lb 9/19/2007 United Kingdom
Primary
Concomitant
Interacting
Urticaria Other Serious 9/26/2006 2 Female 31 lb 8/6/2007 Pharmacist United States
Primary
Concomitant
Wheezing Other Serious 9/11/2006 0 Female 15 lb 8/6/2007 Pharmacist United States
Primary
Concomitant
Myotonia Hospitalization 7/1/2005 55 Female 132 lb 9/20/2007 United Kingdom
Primary
Secondary
Concomitant
Myotonia Hospitalization 7/1/2005 55 Female 132 lb 9/21/2007 United Kingdom
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 12/1/2006 55 Female 132 lb 9/21/2007 United Kingdom
Primary
Concomitant
Interacting
Miosis Hospitalization 9/27/2007 Physician United States
Primary
Secondary
Ventricular Tachycardia Other Serious 69 Male 9/28/2007 Japan
Primary
Concomitant
Sinus Tachycardia Hospitalization 7/1/2005 55 Female 132 lb 10/1/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 12/1/2006 55 Female 132 lb 10/3/2007 United Kingdom
Primary
Concomitant
Interacting
Right Atrial Pressure Increased Other Serious 10/5/2007 Physician United Kingdom
Primary
Concomitant
Pulmonary Congestion Other Serious Male 6 lb 10/8/2007 Japan
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious Male 6 lb 10/8/2007 Japan
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 12/1/2006 55 Female 132 lb 10/9/2007 United Kingdom
Primary
Concomitant
Interacting
Right Atrial Pressure Increased Hospitalization 33 Female 10/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 69 Male 10/12/2007 Japan
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 15 Female 44 lb 10/16/2007 Japan
Primary
Concomitant
Pulmonary Congestion Other Serious Male 6 lb 10/18/2007 Japan
Primary
Secondary
Concomitant
Musculoskeletal Stiffness Other Serious 15 Female 44 lb 10/18/2007 Japan
Primary
Concomitant
Myoclonus Hospitalization 2/19/2007 Female 10/23/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Tachycardia Death 1 Male 10/24/2007 Consumer United States
Primary
Secondary
Ventricular Fibrillation Other Serious 13 lb 11/2/2007 United States
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 56 Male 11/3/2007 Japan
Primary
Concomitant
Myotonia Other Serious 7/1/2005 55 Female 132 lb 11/5/2007 United Kingdom
Primary
Concomitant
Interacting
Delayed Recovery From Anaesthesia Hospitalization 10/3/2007 81 Male 115 lb 11/6/2007 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Death 1 Female 11/7/2007 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Other Serious 35 Male 11/9/2007 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Death 9/8/2007 14 Male 198 lb 11/12/2007 United Kingdom
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 11/12/2006 55 Female 132 lb 11/12/2007 United Kingdom
Primary
Concomitant
Interacting
Tachycardia Death 1 Male 11/8/2007 Consumer United States
Primary
Secondary
Tachycardia Death 1 Male 11/8/2007 United States
Primary
Secondary
Urine Output Decreased Other Serious 5/21/2007 56 Male 11/15/2007 Japan
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 56 Male 11/16/2007 Japan
Primary
Concomitant
Cardiac Arrest Other Serious 4/2/2007 Male 139 lb 11/16/2007 Japan
Primary
Secondary
Concomitant
Myoclonus Hospitalization 2/19/2007 Female 11/19/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious Male 6 lb 11/20/2007 Japan
Primary
Secondary
Concomitant
Delayed Recovery From Anaesthesia Hospitalization 10/3/2007 81 Male 115 lb 11/21/2007 Physician Japan
Primary
Concomitant

Drug Data