Fentanyl combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Life Threatening 11/21/2004 85 Male 1/5/2006 Physician Spain
Primary
Concomitant
Somnolence Other Serious 58 Male 1/21/2006 Other Health Professional United States
Primary
Concomitant
Sedation Life Threatening 12/6/2005 44 Female 1/18/2006 Switzerland
Primary
Secondary
Concomitant
Epistaxis Hospitalization 12/1/2003 4 Female 22 lb 10/6/2005 Physician France
Primary
Concomitant
Respiratory Arrest Life Threatening 10/21/2005 58 Male 1/3/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 52 Female 2/7/2006
Primary
Secondary
Sepsis Hospitalization 7/15/2005 81 Male United States
Primary
Secondary
Intestinal Infarction Death 2/9/2006 78 Male 170 lb 2/16/2006 Physician
Primary
Concomitant
Visual Disturbance Other Serious 9/1/2003 Male 161 lb 2/21/2006 Physician United States
Primary
Concomitant
Tachypnoea Death 2/9/2006 78 Male 170 lb 2/20/2006 Physician
Primary
Concomitant
Hypertensive Cardiomyopathy Death 9/19/2005 48 Female 150 lb 2/22/2006 Physician United States
Primary
Concomitant
Tachycardia Required Intervention 10/29/2005 Female 93 lb 1/26/2006 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Death 94 Female 3/2/2006 United States
Primary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly 9/20/2005 1 Male 7 lb 3/8/2006 Physician United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/26/2006 59 Male 3/1/2006 Physician United States
Primary
Secondary
Concomitant
Injection Site Reaction Death 11/16/2005 66 Male 146 lb 11/30/2005 Pharmacist United States
Primary
Concomitant
Visual Disturbance Other Serious 9/1/2003 Male 161 lb 3/21/2006 Physician United States
Primary
Concomitant
Fatigue Other Serious 2/6/2006 58 Male 164 lb 2/6/2006 Pharmacist United States
Primary
Concomitant
Visual Disturbance Other Serious 9/1/2003 Male 161 lb 3/22/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/27/2005 58 Male 172 lb 3/10/2006 Canada
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 1/25/2006 57 Female 121 lb 3/27/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 3/28/2006 Lawyer United States
Primary
Concomitant
Neonatal Disorder Other Serious 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Neonatal Disorder Other Serious 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Neonatal Disorder Other Serious 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Infusion Related Reaction Required Intervention Female 3/23/2006 Turkey
Primary
Concomitant
Infusion Related Reaction Required Intervention Female 3/23/2006 Turkey
Primary
Concomitant
Infusion Related Reaction Required Intervention Female 3/23/2006 Turkey
Primary
Concomitant
Ventricular Tachycardia Other Serious 5/1/2001 31 Male 183 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Bradycardia Required Intervention Female 3/23/2006 Physician Turkey
Primary
Concomitant
Metastatic Malignant Melanoma Hospitalization Female 100 lb 4/3/2006 Consumer United States
Primary
Concomitant
Somnolence Other Serious 58 Male 3/6/2006 Physician United States
Primary
Concomitant
Lethargy Hospitalization 12/21/2005 84 Male 4/6/2006 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/27/2005 58 Male 172 lb 3/27/2006 Canada
Primary
Secondary
Concomitant
Convulsion Other Serious 9/25/2005 Male 129 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2000 70 Female 146 lb 4/10/2006 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 9/25/2005 20 Male 129 lb 4/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Hesitation 1/1/2005 45 Female 1/23/2006 Consumer United States
Primary
Concomitant
Pain 8/1/2005 64 Male 1/23/2006 Consumer United States
Primary
Concomitant
Urinary Hesitation 1/1/2005 45 Female 1/31/2006 Consumer United States
Primary
Concomitant
Pain 8/1/2005 64 Male 1/31/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 9/25/2005 20 Male 129 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Verbal Stimuli Other Serious 69 Female 141 lb 4/6/2006 Physician Hong Kong
Primary
Secondary
Concomitant
Sternal Fracture Other Serious 6/5/2005 57 Male 4/11/2006 Physician Netherlands
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 3/10/2006 69 Male 185 lb 4/11/2006 Pharmacist United States
Primary
Concomitant
Pregnancy With Contraceptive Device Congenital Anomaly 9/20/2005 1 Male 7 lb 4/11/2006 Physician United States
Primary
Concomitant
Platelet Disorder Other Serious 2/6/2006 56 Male 251 lb 4/12/2006 Pharmacist United States
Primary
Concomitant
Convulsion Required Intervention 9/25/2005 20 Male 129 lb 4/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ovarian Cancer Metastatic Other Serious 1/25/2006 Female 4/26/2006 Physician Netherlands
Primary
Concomitant
Drug Level Decreased Other Serious 9/25/2005 20 Male 129 lb 4/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Overdose Other Serious Male 141 lb 4/26/2006 Physician United States
Primary
Secondary
Vomiting Hospitalization 4/3/2006 69 Male 5/2/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Head Injury Other Serious 9/25/2005 Male 129 lb 5/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Death 3/26/2006 73 Male 4/24/2006 Physician United States
Primary
Secondary
Concomitant
Wrong Drug Administered Other Serious 3/21/2006 35 Male 258 lb 5/1/2006 Physician United Kingdom
Primary
Concomitant
Somnolence Other Serious 44 Female 5/3/2006 Physician Brazil
Primary
Concomitant
Ventricular Fibrillation Life Threatening 3/28/2006 51 Female 5/9/2006 Other Health Professional Argentina
Primary
Concomitant
Interacting
Hypertensive Cardiomyopathy Death 9/19/2005 48 Female 150 lb 5/9/2006 Physician United States
Primary
Concomitant
Whole Blood Transfusion Other Serious 2/1/2006 66 Female 112 lb 5/19/2006 United States
Primary
Secondary
Concomitant
Tinnitus Other Serious 44 Female 5/12/2006 Physician Canada
Primary
Concomitant
Respiratory Arrest Death 4/1/2006 77 Male 5/16/2006 Physician Japan
Primary
Secondary
Concomitant
Neonatal Disorder Other Serious 5/12/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 1/25/2006 57 Female 121 lb 5/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Colorectal Cancer Metastatic Hospitalization 30 Female 5/30/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 4/3/2006 65 Male 5/30/2006 Consumer France
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 35 Female 116 lb 5/23/2006 Physician China
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 1/1/2006 69 Male 185 lb 5/24/2006 Physician United States
Primary
Concomitant
Palpable Purpura Hospitalization 2/26/2006 66 Male 152 lb 5/26/2006 Other Health Professional Brazil
Primary
Concomitant
Cytomegalovirus Infection Hospitalization 3/30/2006 65 Male 6/5/2006 Physician Sweden
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Death 94 Female 5/26/2006 Other Health Professional United States
Primary
Concomitant
Insomnia Other Serious 5/2/2006 Male 441 lb 5/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 22 Female 6/7/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 67 Female 123 lb 6/9/2006 Other Health Professional Japan
Primary
Concomitant
Oedema Peripheral 6/14/2005 49 4/6/2006 Physician United States
Primary
Concomitant
Pain 8/1/2005 64 Male 4/6/2006 Consumer United States
Primary
Concomitant
Neuromuscular Block Prolonged Required Intervention 1/12/2006 67 Female 190 lb 4/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Swelling Other Serious 10/6/2005 46 Female 200 lb 4/7/2006 Physician United States
Primary
Concomitant
Respiratory Rate Increased Death 4/1/2006 77 Male 6/19/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 5/30/2006 35 Female 7/14/2006 Physician Japan
Primary
Concomitant
Drug Toxicity Other Serious 18 Male 141 lb 6/14/2006 Physician United States
Primary
Secondary
Myoclonus Hospitalization 4/23/2006 Male 7/18/2006 Pharmacist United States
Primary
Concomitant
Overdose Other Serious 34 Male 8/7/2006 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 5/30/2006 35 Female 8/1/2006 Physician Japan
Primary
Concomitant
Neutropenia 4/11/2006 71 Female 143 lb 7/6/2006 Physician United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/1/2006 36 Male 210 lb 8/2/2006 United States
Primary
Secondary
Concomitant
Tryptase Increased Other Serious Female 8/9/2006 Physician Ireland
Primary
Concomitant
Overdose Other Serious 34 Male 8/22/2006 Consumer United States
Primary
Concomitant
Neutropenia Other Serious 7/10/2006 69 Male 137 lb 8/17/2006 Belgium
Primary
Concomitant
Hepatic Enzyme Abnormal Other Serious 6/14/2006 56 Male 162 lb 6/14/2006 Pharmacist United States
Primary
Concomitant
Urinary Retention Other Serious 6/12/2006 56 Male 162 lb 6/12/2006 Pharmacist United States
Primary
Concomitant
Pleural Effusion Hospitalization 5/22/2006 35 Female 113 lb 8/28/2006 Physician Japan
Primary
Concomitant
Flushing Other Serious 71 Female 9/1/2006 Physician Japan
Primary
Secondary
Ventricular Extrasystoles Death 8/22/2006 50 Female 130 lb 8/31/2006 Physician United States
Primary
Concomitant
Wound Secretion Other Serious 35 Female 116 lb 9/1/2006 Other Health Professional China
Primary
Secondary
Concomitant
Anaemia Hospitalization 8/31/2006 66 Male 138 lb 9/7/2006 Pharmacist United States
Primary
Concomitant
Neutropenia Other Serious 7/10/2006 69 Male 137 lb 8/25/2006 Belgium
Primary
Concomitant
Drug Toxicity Death 1/1/2005 49 Male 9/19/2006 Physician United States
Primary
Secondary
Vomiting Other Serious 4/17/2004 69 Female 9/21/2006
Primary
Concomitant
Vomiting Other Serious 4/17/2004 69 Female 9/21/2006
Primary
Concomitant
Wound Dehiscence Other Serious 35 Female 116 lb 9/28/2006 United States
Primary
Concomitant
Interacting
Weight Increased Hospitalization 5/22/2006 35 Female 113 lb 9/25/2006 Physician Japan
Primary
Concomitant
Renal Tubular Necrosis Required Intervention 8/18/2006 54 Male 142 lb 9/26/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Hospitalization 3/26/2006 86 Male 119 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 8/31/2006 24 Female 119 lb 10/9/2006 Consumer United Kingdom
Primary
Concomitant
Wound Other Serious 2/1/2006 Female 176 lb 10/10/2006 Physician Poland
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/25/2006 Male 10/5/2006 Other Health Professional United States
Primary
Concomitant
Dyspnoea Hospitalization 8/7/2006 45 Female 105 lb 9/19/2006 Consumer United States
Primary
Secondary
Concomitant
Feeding Tube Complication Hospitalization 8/26/2006 45 Female 105 lb 9/21/2006 Consumer United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization Male 10/19/2006
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/12/2006 68 Male 201 lb 10/24/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 21 Male 174 lb 10/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 80 Male 10/18/2006 Physician United States
Primary
Secondary
Concomitant
Life Support Hospitalization 5/2/2006 48 Male 10/30/2006 Other Health Professional United States
Primary
Secondary
Respiratory Depression Hospitalization 78 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Respiratory Depression Hospitalization 78 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Patent Ductus Arteriosus Other Serious 10/24/2006 0 Male 11/1/2006 Spain
Primary
Concomitant
Weight Increased Hospitalization 5/22/2006 35 Female 113 lb 11/3/2006 Physician Japan
Primary
Concomitant
Tachycardia Hospitalization 5/2/2003 55 Male 238 lb 11/6/2006 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Death 56 Male 154 lb 11/16/2006
Primary
Secondary
Neurotoxicity Hospitalization 2/26/2006 66 Male 152 lb 11/10/2006 Other Health Professional Brazil
Primary
Concomitant
Pulmonary Oedema Other Serious 84 Female 11/21/2006 Japan
Primary
Secondary
Concomitant
Respiratory Depression Death 26 Female 112 lb 11/21/2006
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 11/1/2006 44 Male 11/13/2006 Pharmacist United States
Primary
Concomitant
Wound Other Serious 2/1/2006 Female 176 lb 11/29/2006 Physician Poland
Primary
Concomitant
Intestinal Infarction Death 2/9/2006 Male 170 lb 11/29/2006 Physician
Primary
Concomitant
Vomiting Life Threatening 9/23/2006 Male 240 lb 11/29/2006 Physician Canada
Primary
Concomitant
Drug Toxicity Death 1/1/2005 49 Male 12/4/2006 Physician United States
Primary
Secondary
Anaphylactic Reaction Life Threatening 11/1/2006 51 Female 12/7/2006 Consumer United Kingdom
Primary
Secondary
Drug Exposure During Pregnancy 11/22/2006 24 Female 11/30/2006 Other Health Professional United States
Primary
Secondary
Pulmonary Oedema Death 4 Male 12/14/2006 Other Health Professional Canada
Primary
Concomitant
Vena Cava Thrombosis Life Threatening 9/23/2006 Male 240 lb 12/14/2006 Physician Canada
Primary
Concomitant
Respiratory Depression Other Serious Female 123 lb 12/19/2006
Primary
Secondary
Concomitant
Ruptured Ectopic Pregnancy Hospitalization 11/26/2006 36 Female 153 lb 12/11/2006 United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 46 Female 12/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ultrasound Scan Abnormal Other Serious 46 Female 12/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 46 Female 12/21/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 46 Female 12/29/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neurotoxicity Hospitalization 2/26/2006 Male 152 lb 1/2/2007 Brazil
Primary
Concomitant
Tachypnoea Required Intervention 1/1/2006 46 Female 12/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Other Serious 46 Female 12/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 46 Female 1/10/2007 United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Other Serious 46 Female 1/15/2007 United Kingdom
Primary
Secondary
Concomitant
Troponin I Increased Life Threatening 1/14/2007 76 Female 150 lb 1/17/2007 Physician Australia
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 2/12/2006 Male 165 lb 3/24/2006 Pharmacist United States
Primary
Concomitant
Pain In Extremity Required Intervention 10/1/2006 Male 1/12/2007 Physician United States
Primary
Concomitant
Patent Ductus Arteriosus Other Serious 10/24/2006 0 Male 1/25/2007 Physician Spain
Primary
Concomitant
Cardio-respiratory Arrest Death 49 Unknown 1/25/2007 Physician United States
Primary
Secondary
Respiratory Depression Death 26 Female 112 lb 1/29/2007 Physician Germany
Primary
Concomitant
Paraesthesia Other Serious 8/31/2004 53 Male 2/7/2007 Physician Czech Republic
Primary
Secondary
Concomitant
Intestinal Infarction Hospitalization 1/31/2006 Male 170 lb 2/7/2007 Physician
Primary
Concomitant

Drug Data