Fentanyl combined with Midazolam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Respiration Abnormal Life Threatening 11/8/2005 49 Male 12/1/2005 Other Health Professional United States
Primary
Secondary
Hepatitis Hospitalization 10/23/2005 67 Female 1/25/2006 Other Health Professional Australia
Primary
Secondary
Dysuria Other Serious 11/11/2005 64 Male 1/25/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Wound Haemorrhage Hospitalization 8/13/2005 54 Male 2/3/2006 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/9/2006
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/9/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 1/24/2006 66 Male 317 lb 2/9/2006 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Intestinal Infarction Death 2/9/2006 78 Male 170 lb 2/16/2006 Physician
Primary
Concomitant
Nosocomial Infection Other Serious 10/6/2003 Male 240 lb 2/20/2006 Physician United States
Primary
Secondary
Concomitant
Tachypnoea Death 2/9/2006 78 Male 170 lb 2/20/2006 Physician
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/16/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 12/16/2005 46 Female 2/28/2006 Physician Brazil
Primary
Concomitant
Loss Of Consciousness Other Serious 51 Male 3/2/2006 United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 12/16/2005 46 Female 3/13/2006 Physician Brazil
Primary
Concomitant
Injection Site Reaction Death 11/16/2005 66 Male 146 lb 11/30/2005 Pharmacist United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/16/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/16/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 38 Male 220 lb 3/16/2006 Other Health Professional United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/2/2006 United Kingdom
Primary
Secondary
Concomitant
Swelling Face Death 1/21/2003 14 Female 3/10/2006 Canada
Primary
Secondary
Concomitant
Sedation Life Threatening 12/28/2005 83 Female 115 lb 1/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sedation Life Threatening 12/28/2005 83 Female 115 lb 1/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Neonatal Disorder Other Serious 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Neonatal Disorder Other Serious 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Neonatal Disorder Other Serious 3/24/2006 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 51 Female 3/27/2006 United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 4/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 4/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 46 Male 4/11/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Spinal Cord Infarction Other Serious 67 Female 4/14/2006 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/13/2005 49 Female 265 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Resuscitation Life Threatening 7/14/2005 59 Female 183 lb 6/19/2006 Pharmacist United States
Primary
Concomitant
Chills Other Serious 10/18/2005 Male 128 lb 6/28/2006 Japan
Primary
Secondary
Concomitant
Wheezing Life Threatening 3/11/2006 51 Female 8/11/2006 Consumer Australia
Primary
Secondary
Oxygen Saturation Decreased Hospitalization 9/7/2005 62 Female 8/11/2006 Pharmacist United States
Primary
Secondary
Wrong Technique In Drug Usage Process Other Serious 29 Female 216 lb 8/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 7/19/2006 53 Female 126 lb 8/23/2006 Pharmacist United States
Primary
Concomitant
Neurotoxicity Other Serious 1 Female 12 lb 8/26/2006 France
Primary
Concomitant
Troponin I Increased Other Serious 12/1/2002 17 Female 9/11/2006 Other Health Professional United States
Primary
Concomitant
Post Procedural Complication Hospitalization 9/1/2006 Female 157 lb 10/6/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 8/22/2005 73 Female 170 lb 8/29/2006 Other Health Professional United States
Primary
Concomitant
Respiratory Depression Hospitalization 78 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Respiratory Depression Hospitalization 78 Female 11/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Urticaria Other Serious 8/26/2005 76 Male 176 lb 11/15/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Thrombocythaemia Other Serious 10/16/2006 71 Male 11/27/2006 Other Health Professional Turkey
Primary
Concomitant
Intestinal Infarction Death 2/9/2006 Male 170 lb 11/29/2006 Physician
Primary
Concomitant
Retinal Artery Occlusion Disability 49 Female 121 lb 11/30/2006 Physician China
Primary
Concomitant
Wound Secretion Other Serious 10/23/2006 67 Female 12/12/2006 Other Health Professional Australia
Primary
Concomitant
No Adverse Effect Hospitalization 1/9/2007 Female 2/7/2007 Physician United States
Primary
Secondary
Concomitant
Erythema Other Serious 6/8/2007 41 Female 7/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Loss Of Consciousness Hospitalization 1/12/2007 73 Female 7/24/2007 Pharmacist United States
Primary
Secondary
Cardiac Arrest 7/24/2007 38 Male 256 lb 7/30/2007 United States
Primary
Concomitant
Unresponsive To Stimuli Disability 4/14/2007 68 Male 262 lb 7/30/2007 Pharmacist United States
Primary
Concomitant
Erythema Life Threatening 6/8/2007 41 Female 8/2/2007 United Kingdom
Primary
Secondary
Laryngospasm Other Serious 6/8/2007 41 Female 7/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Multi-organ Failure Other Serious 4/20/2007 44 Female 142 lb 8/2/2007 Physician United States
Primary
Concomitant
Oxygen Saturation Decreased 35 Male 10/8/2007 Other Health Professional Australia
Primary
Secondary
Ulcer Other Serious 75 Female 10/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ulcer Other Serious 1/1/2002 75 Female 10/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Musculoskeletal Stiffness Other Serious 15 Female 44 lb 10/18/2007 Japan
Primary
Concomitant
Weight Decreased Other Serious 1/1/2000 71 Female 10/20/2007 United States
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 70 Female 86 lb 10/22/2007 Physician Japan
Primary
Secondary
Concomitant
Bradycardia Life Threatening 4/30/2007 69 Male 165 lb 10/25/2007 Other Health Professional Australia
Primary
Secondary
Transient Ischaemic Attack Other Serious 7/12/2005 23 Male 150 lb 7/3/2008 Consumer United States
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 9/8/2008 Female 136 lb 9/12/2008 United States
Primary
Concomitant
Cardiac Arrest Life Threatening 1/23/2007 41 Female 9/10/2008 Other Health Professional New Zealand
Primary
Concomitant
Respiratory Distress Other Serious 8/13/2008 69 Female 9/24/2008 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Encephalopathy Required Intervention 49 Female 9/22/2008 Canada
Primary
Secondary
Concomitant
Venous Thrombosis Limb Other Serious 8/9/2007 Male 187 lb 9/25/2008 Physician Germany
Primary
Concomitant
Respiratory Depression Required Intervention 9/9/2008 67 Male 9/23/2008 Pharmacist United States
Primary
Secondary
Adrenal Suppression Other Serious 9/25/2008 Other Health Professional United States
Primary
Secondary
Ventricular Tachycardia Hospitalization 5/19/2008 Male 9/30/2008 Other Health Professional France
Primary
Secondary
Concomitant
Musculoskeletal Disorder Other Serious 10/16/2007 Male 205 lb 10/7/2008 Physician Italy
Primary
Concomitant
Aspiration Life Threatening 6/5/2008 Male 146 lb 10/15/2008 Physician Japan
Primary
Concomitant
Sinus Bradycardia Other Serious 65 Female 10/16/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/14/2008 1/9/2009 Physician Japan
Primary
Concomitant
Arteriospasm Coronary Life Threatening 60 Female 119 lb 3/26/2009 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 51 Male 192 lb 4/2/2009 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 66 Male 176 lb 7/15/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Septic Shock Other Serious 4/29/2008 29 9/2/2009 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 4/29/2008 29 9/15/2009 Physician Japan
Primary
Concomitant
Drug Level Below Therapeutic Other Serious 14 Female 12/23/2009 Australia
Primary
Concomitant
Thrombocytopenia Life Threatening 7/14/2008 9 Female 53 lb 1/14/2010 Physician Japan
Primary
Concomitant
Serotonin Syndrome Other Serious 39 Female 2/19/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Hypertensive Crisis Life Threatening 87 Female 2/25/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Premature Baby Death Female 1 lb 2/28/2010 Consumer United States
Primary
Concomitant
Post Procedural Haemorrhage Other Serious 67 Female 99 lb 3/2/2010 Other Health Professional Japan
Primary
Concomitant
Anaphylactic Reaction Other Serious 5/17/2010 57 Male 6/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypertension Other Serious 1/1/2008 65 Male 258 lb 6/15/2010 Lawyer United States
Primary
Concomitant
Staphylococcal Infection Other Serious 4/14/2008 29 Male 278 lb 6/16/2010 Lawyer United States
Primary
Concomitant
Drug Withdrawal Syndrome Other Serious 3/21/2007 Female 9 lb 6/17/2010 Physician United States
Primary
Secondary
Thrombocytopenia Other Serious 6/11/2009 60 Female 251 lb 6/29/2010 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Disability 1/5/2010 75 Male 7/14/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Methaemoglobinaemia Other Serious 45 Female 95 lb 7/14/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 7/14/2010 26 Female 176 lb 7/26/2010 Physician Portugal
Primary
Concomitant
Vascular Graft Thrombosis Other Serious Male 8/17/2010 Lawyer United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 39 Female 8/18/2010 Other Health Professional United States
Primary
Concomitant
Interacting
Ulcer Other Serious 1/1/2002 75 Female 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Failure Other Serious 1/1/2002 75 Female 10/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 10/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 7/6/2010 11 Male 10/20/2010 Pharmacist Japan
Primary
Secondary
Lymphocyte Stimulation Test Positive Hospitalization 7/6/2010 11 Male 10/21/2010 Physician Japan
Primary
Secondary
Acute Hepatic Failure Other Serious 1/1/2002 75 Female 10/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Disease Other Serious 6/1/2010 13 Male 120 lb 10/22/2010 Physician Netherlands
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 139 lb 10/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 2/1/2008 12 Female 66 lb 10/28/2010 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 139 lb 10/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 4/1/2008 29 Male 278 lb 10/28/2010 Lawyer United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2002 75 Female 11/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Hepatic Failure Other Serious 1/1/2002 75 Female 11/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 1/1/2006 69 Female 11/5/2010 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 139 lb 11/5/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 1/1/2008 36 Male 289 lb 11/9/2010 Other Health Professional United States
Primary
Concomitant
Haematemesis Life Threatening 6/23/2010 8 Male 37 lb 11/15/2010 Physician Thailand
Primary
Secondary
Concomitant
Tachypnoea Other Serious 24 Male 11/16/2010
Primary
Secondary
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 11/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lung Disorder Other Serious 49 Female 128 lb 11/18/2010 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Other Serious 31 Male 11/19/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Procedural Complication Life Threatening 5/27/2010 74 Male 163 lb 11/19/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/1/2007 58 Female 123 lb 11/22/2010 Lawyer United States
Primary
Secondary
Concomitant
Renal Disorder Life Threatening 11/12/2010 0 Male 7 lb 11/14/2010 Physician United States
Primary
Concomitant
Foetal Growth Restriction Other Serious 11/23/2010 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 11/24/2010 Other Health Professional United States
Primary
Concomitant
Serotonin Syndrome Life Threatening 49 Female 11/29/2010 Other Health Professional Austria
Primary
Concomitant
Interacting
Oligohydramnios Other Serious 20 Female 132 lb 11/29/2010 Pharmacist United States
Primary
Secondary
Stridor Hospitalization Female 11/29/2010 Physician Australia
Primary
Secondary
Thrombocytopenia Other Serious 10/1/2007 75 Male 157 lb 11/29/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 9 Female 73 lb 12/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/20/2007 69 Female 139 lb 12/2/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 53 Female 146 lb 12/2/2010 Other Health Professional United States
Primary
Concomitant
Wound Haemorrhage Other Serious 12/1/2007 57 Female 12/2/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 12/2/2010 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 75 Female 138 lb 12/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 1/1/2008 36 Male 289 lb 12/15/2010 Other Health Professional United States
Primary
Concomitant
Cardiac Arrest Life Threatening 5/27/2010 74 Male 163 lb 12/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Splenomegaly Other Serious 4/4/2008 67 Male 268 lb 12/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 5/30/2008 67 Male 12/16/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/26/2004 52 Female 168 lb 12/20/2010 United States
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 1/6/2011 79 Male 150 lb 1/18/2011 Physician Chile
Primary
Secondary
Concomitant
Intra-uterine Death Hospitalization 20 Female 1/18/2011 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 70 Female 1/5/2011 Physician Spain
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/23/2010 8 Male 35 lb 1/20/2011 Physician Thailand
Primary
Secondary
Concomitant
Anxiety Hospitalization 12/6/2010 39 Male 208 lb Pharmacist United States
Primary
Secondary
Anaphylactic Reaction Hospitalization 11/16/2010 60 Male 1/26/2011 Physician Australia
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/1/2007 65 Male 1/27/2011 Other Health Professional United States
Primary
Concomitant
Multi-organ Failure Death 7/1/2007 1 Male 18 lb 1/27/2011 Physician United States
Primary
Concomitant

Drug Data