Fentanyl Citrate combined with Sevoflurane

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sleep Apnoea Syndrome Hospitalization 1/24/2005 2 Female 24 lb 1/4/2006 Physician Japan
Primary
Concomitant
Blood Creatinine Increased 2/16/2005 69 218 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
Blood Creatinine Increased 2/16/2005 69 218 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
Renal Impairment Disability 12/10/2005 80 Male 126 lb 1/12/2006 Physician Japan
Primary
Concomitant
Wheezing Other Serious 24 Male 2/24/2006 Physician Germany
Primary
Concomitant
Injection Site Swelling Hospitalization 1/16/2006 55 Male 2/14/2006 Japan
Primary
Concomitant
Myoglobin Blood Increased Life Threatening 12/18/2005 44 Male 2/22/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 8 Male 64 lb 3/9/2006 France
Primary
Concomitant
White Blood Cell Count Increased Death 30 Male 161 lb 3/10/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Metabolic Acidosis Required Intervention 15 Male 119 lb 3/22/2006 Physician Japan
Primary
Concomitant
Cerebral Infarction Other Serious 3/1/2006 71 Female 4/17/2006 Other Health Professional Japan
Primary
Concomitant
Procedural Complication Life Threatening 1/13/2006 17 Female 1/23/2006 Other Health Professional Japan
Primary
Concomitant
Ventricular Fibrillation Required Intervention 11/27/2005 64 Male 4/12/2006 Pharmacist Japan
Primary
Concomitant
Vascular Injury Other Serious 3/1/2006 71 Female 4/19/2006 United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 7/14/2004 Male 143 lb 5/3/2006 Other Health Professional Japan
Primary
Concomitant
Respiratory Depression Required Intervention 21 Male 77 lb 5/12/2006 Physician Japan
Primary
Concomitant
Hypoventilation Life Threatening 1/13/2006 17 Female 5/17/2006 Japan
Primary
Concomitant
Cerebral Infarction Other Serious 3/1/2006 71 Female 6/6/2006 Other Health Professional Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 47 Male 6/6/2006 Other Health Professional Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 21 Male 203 lb 6/8/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 22 Male 6/8/2006 Other Health Professional Japan
Primary
Concomitant
Skin Exfoliation Other Serious 1/20/2006 55 Male 5/29/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Vascular Injury Other Serious 3/1/2006 71 Female 6/6/2006 United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 47 Male 6/16/2006 Other Health Professional Japan
Primary
Concomitant
Cerebral Infarction Life Threatening 3/28/2006 71 Female 6/19/2006 Other Health Professional Japan
Primary
Concomitant
Metabolic Acidosis Other Serious 22 Male 7/5/2006 Other Health Professional Japan
Primary
Concomitant
Vascular Injury Life Threatening 3/28/2006 71 Female 6/27/2006 United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 18 Female 7/24/2006 Physician Japan
Primary
Secondary
Concomitant
Extrasystoles 2/24/2005 18 Female 8/16/2006 Physician Japan
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 67 Male 10/27/2006 Other Health Professional Japan
Primary
Concomitant
Bronchospasm Life Threatening 1/13/2006 17 Female 10/18/2006 Japan
Primary
Concomitant
Musculoskeletal Stiffness Hospitalization 15 Female 10/30/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Urticaria Generalised Life Threatening 10/13/2006 26 Female 10/24/2006 Finland
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 70 Male 11/3/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Depression Hospitalization 78 Female 11/3/2006
Primary
Secondary
Concomitant
Movement Disorder Disability 88 Female 141 lb 11/7/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious 80 Male 11/8/2006 Japan
Primary
Concomitant
Tracheomalacia Other Serious 66 Female 106 lb 11/8/2006
Primary
Secondary
Acute Myocardial Infarction Other Serious 80 Male 11/8/2006 Japan
Primary
Concomitant
Tachycardia Other Serious 8/24/2006 58 Male 165 lb 11/9/2006 Consumer United Kingdom
Primary
Concomitant
Stress Cardiomyopathy Other Serious 1/1/2006 67 Male 11/10/2006 Other Health Professional Japan
Primary
Concomitant
Respiratory Failure Life Threatening 7/9/2006 76 Male 11/14/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Procedural Complication Other Serious 7/21/2006 6 Male 11/8/2006 Other Health Professional Japan
Primary
Secondary
Anaphylactic Shock 73 Female 11/9/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 29 Female 11/22/2006 Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 8/3/2006 Female 11/30/2006 Other Health Professional Japan
Primary
Concomitant
Respiratory Failure Life Threatening 7/9/2006 76 Male 94 lb 12/4/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 3/1/2005 71 Male 137 lb 11/22/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 7/5/2006 Female 12/6/2006 Japan
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 4/22/2006 Male 12/18/2006 Japan
Primary
Concomitant
Respiratory Failure Life Threatening 7/9/2006 76 Male 94 lb 12/26/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 4/30/2004 14 Female 119 lb 12/20/2006 Other Health Professional Japan
Primary
Concomitant
Tachycardia Hospitalization 8/3/2006 Female 73 lb 1/3/2007 Other Health Professional Japan
Primary
Concomitant
Pyrexia Hospitalization 61 Male 130 lb 1/19/2007 Other Health Professional Japan
Primary
Concomitant
Pyrexia Hospitalization 61 Male 130 lb 1/30/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Hypersensitivity Life Threatening 11/7/2006 26 Female 1/24/2007 Japan
Primary
Concomitant
Pharyngolaryngeal Pain Life Threatening 11/7/2006 26 Female 1/26/2007 Japan
Primary
Concomitant
Myoglobin Blood Increased Hospitalization 61 Male 130 lb 1/30/2007 Other Health Professional Japan
Primary
Concomitant
Sinus Arrest Hospitalization 5/25/2006 Male 2/9/2007 Japan
Primary
Secondary
Concomitant
Myoglobin Blood Increased Hospitalization 61 Male 130 lb 2/12/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Sick Sinus Syndrome Hospitalization 5/25/2006 Male 97 lb 2/22/2007 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/30/2004 14 Female 119 lb 2/19/2007 Japan
Primary
Concomitant
Pulmonary Embolism Other Serious 7/5/2006 Female 3/9/2007 Japan
Primary
Concomitant
Paraplegia Disability 83 Male 86 lb 4/16/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 78 Female 5/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Lung Disorder Other Serious 58 Male 6/28/2007 Other Health Professional Japan
Primary
Concomitant
Compartment Syndrome Hospitalization 72 Female 6/29/2007 Other Health Professional Japan
Primary
Concomitant
Hypothermia Required Intervention 0 Female 7 lb 6/29/2007 Physician United States
Primary
Secondary
Concomitant
Lung Disorder Other Serious 58 Male 7/6/2007 Other Health Professional Japan
Primary
Concomitant
Sinus Tachycardia Life Threatening 8/18/2006 63 Male 7/9/2007 Japan
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Hospitalization 1/24/2005 2 Female 24 lb 11/23/2005 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 5/8/2007 Male 7/26/2007 Other Health Professional Japan
Primary
Concomitant
Pulmonary Oedema Life Threatening 40 Female 161 lb 7/30/2007 United States
Primary
Concomitant
Tremor Required Intervention 6 Male 55 lb 7/27/2007 Physician United States
Primary
Secondary
Concomitant
Sinus Tachycardia Life Threatening 8/18/2006 63 Male 7/26/2007 Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 5/8/2007 Male 8/8/2007 Other Health Professional Japan
Primary
Concomitant
Sensory Loss Required Intervention 15 Male 152 lb 8/8/2007 Physician Australia
Primary
Secondary
Concomitant
Myotonia Hospitalization 7/1/2005 55 Female 132 lb 9/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Delayed Recovery From Anaesthesia Hospitalization 65 Female 11/2/2007 Physician Japan
Primary
Concomitant
Ventricular Dysfunction Required Intervention 1 Male 9 lb 11/6/2007 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 1 Male 9 lb 11/15/2007 United States
Primary
Secondary
Concomitant
Delayed Recovery From Anaesthesia Life Threatening 65 Female 106 lb 11/16/2007 Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 3/22/2007 69 Male 111 lb 11/21/2007 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 1 Male 9 lb 12/13/2007 United States
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 66 Male 12/20/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Somnolence Life Threatening 12/19/2007 38 Female 159 lb 1/14/2008 United States
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 78 Male 1/29/2008 Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 3/22/2007 69 Male 111 lb 1/30/2008 Japan
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 12/19/2007 38 Female 160 lb 1/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Unwanted Awareness During Anaesthesia Other Serious 2/21/2006 Male 134 lb 3/7/2008 Japan
Primary
Concomitant
Rash Papular Other Serious 9/27/2007 49 Female 119 lb 4/1/2008 Physician Japan
Primary
Secondary
Concomitant
Tachycardia 4/2/2007 2 Male 4/2/2008 Japan
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 47 Male 4/24/2008 Other Health Professional Australia
Primary
Concomitant
Spinal Cord Infarction Hospitalization 21 Male 119 lb 4/28/2008 Physician Japan
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 33 Female 202 lb 4/30/2008 Physician United Kingdom
Primary
Concomitant
Migraine With Aura Other Serious 15 Male 152 lb 4/30/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 7/1/2005 55 Female 132 lb 5/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Guillain-barre Syndrome Life Threatening 83 Male 99 lb 5/19/2008 Physician Japan
Primary
Concomitant
Pulmonary Oedema Life Threatening 35 Female 165 lb 5/21/2008 Other Health Professional Turkey
Primary
Concomitant
Rhabdomyolysis 4/17/2008 37 Male 5/20/2008 Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 4/28/2008 Male 135 lb 6/2/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 4/17/2008 37 Male 5/28/2008 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 5/29/2008 Female 6/17/2008 Physician Japan
Primary
Concomitant
Respiration Abnormal Other Serious 61 Male 115 lb 6/20/2008 Japan
Primary
Concomitant
Vomiting Other Serious 5/29/2008 Female 97 lb 6/23/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 5/29/2008 Female 97 lb 6/30/2008 Physician Japan
Primary
Concomitant
Vomiting Other Serious 5/29/2008 Female 97 lb 7/9/2008 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 53 Female 7/10/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Death 53 Female 7/16/2008 Physician Japan
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 7/1/2005 55 Female 132 lb 7/17/2008 United Kingdom
Primary
Concomitant
Interacting
No Adverse Event 55 Female 132 lb 7/18/2008 United Kingdom
Primary
Concomitant
Interacting
Sinus Tachycardia Hospitalization 7/1/2005 55 Female 132 lb 7/18/2008 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 53 Female 7/18/2008 Consumer Japan
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 53 Female 7/21/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Death 53 Female 7/28/2008 Consumer Japan
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 9/16/2005 53 Female 7/30/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 53 Female 7/31/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 9/16/2005 53 Female 8/11/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 53 Female 8/13/2008 Japan
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 9/16/2005 53 Female 8/14/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiration Abnormal Other Serious 61 Male 115 lb 9/19/2008 Japan
Primary
Secondary
Concomitant
Urticaria Life Threatening 9/29/2008 63 Male 10/7/2008 Finland
Primary
Concomitant
Serotonin Syndrome Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 65 Male 10/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 37 Male 134 lb 10/17/2008 Japan
Primary
Secondary
Concomitant
Angle Closure Glaucoma Other Serious 67 Female 104 lb 10/17/2008 Japan
Primary
Concomitant
Myocardial Infarction Other Serious 8/18/2008 Male 10/20/2008 Other Health Professional Japan
Primary
Concomitant
Blood Pressure Decreased Other Serious 7/18/2008 59 Male 220 lb 10/21/2008 Pharmacist United States
Primary
Concomitant
Sensorimotor Disorder Disability 8/11/2008 27 Female 90 lb 10/27/2008 Physician Japan
Primary
Secondary
Concomitant
Headache Hospitalization 8/7/2007 Female 106 lb 10/29/2008 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 37 Male 134 lb 10/29/2008 Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/17/2008 Male 134 lb 11/3/2008 Japan
Primary
Secondary
Concomitant
Headache Hospitalization 8/7/2007 Female 106 lb 11/6/2008 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 4/28/2008 Male 135 lb 11/20/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/17/2008 Male 134 lb 11/20/2008 Japan
Primary
Secondary
Concomitant
Sinus Tachycardia Life Threatening 11/7/2006 26 Female 11/19/2008 Japan
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 8/27/2007 85 Male 119 lb 11/20/2008 Physician Japan
Primary
Concomitant
Sinus Tachycardia Life Threatening 11/7/2006 26 Female 11/19/2008 Japan
Primary
Concomitant
Subdural Haematoma Other Serious 53 Male 12/9/2008 Physician Japan
Primary
Concomitant
Subdural Haematoma Other Serious 53 Male 12/11/2008 Physician Japan
Primary
Concomitant
Electrocardiogram St Segment Elevation Other Serious 66 Male 12/11/2008 Other Health Professional Japan
Primary
Concomitant
Post Procedural Complication Other Serious 3/12/2008 Male 137 lb 12/16/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 9/8/2007 Female 12/16/2008 Physician Japan
Primary
Concomitant
Hallucination, Visual Other Serious 12/19/2008 Physician Japan
Primary
Secondary
Concomitant
Postoperative Fever Other Serious 3/12/2008 Male 1/13/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Extrasystoles Other Serious 1/13/2009 Female 121 lb 1/29/2009 Venezuela
Primary
Concomitant
Threatened Labour Hospitalization 6/22/2008 40 Female 2/6/2009 Japan
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Life Threatening 1/15/2009 63 Female 3/2/2009 Physician Japan
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Life Threatening 1/15/2009 63 Female 3/9/2009 Physician Japan
Primary
Concomitant
Horner's Syndrome Other Serious 32 Female 3/13/2009 Other Health Professional Turkey
Primary
Secondary
Concomitant

Drug Data