Fentanyl Citrate combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sleep Apnoea Syndrome Hospitalization 1/24/2005 2 Female 24 lb 1/4/2006 Physician Japan
Primary
Concomitant
Blood Creatinine Increased 2/16/2005 69 218 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
Blood Creatinine Increased 1/26/2005 74 135 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 12/18/2004 38 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 9/12/2005 Physician United States
Primary
Concomitant
Blood Creatinine Increased 2/16/2005 69 218 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
Blood Creatinine Increased 1/26/2005 74 135 lb 1/6/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 12/15/2004 1/6/2006 Physician United States
Primary
Concomitant
Renal Impairment Disability 12/10/2005 80 Male 126 lb 1/12/2006 Physician Japan
Primary
Concomitant
Somnolence Hospitalization 25 Female 132 lb 1/26/2006 Other Health Professional India
Primary
Secondary
Concomitant
Somnolence Hospitalization 25 Female 132 lb 1/26/2006 Other Health Professional India
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 10/26/2005 44 Female 2/6/2006 Physician Germany
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 79 Female 2/10/2006 United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 2/1/2006 63 Female 121 lb 2/14/2006 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 75 Female 2/15/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 1/1/2006 51 Female 2/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 24 Male 2/24/2006 Physician Germany
Primary
Concomitant
Hypotension Other Serious 74 Male 2/24/2006 United States
Primary
Concomitant
Injection Site Swelling Hospitalization 1/16/2006 55 Male 2/14/2006 Japan
Primary
Concomitant
Loss Of Consciousness Other Serious 51 Male 2/28/2006
Primary
Secondary
Concomitant
Myoglobin Blood Increased Life Threatening 12/18/2005 44 Male 2/22/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Procedural Complication Life Threatening 1/18/2005 59 Female 291 lb 2/24/2006 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 58 Male 2/21/2006 Physician United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 51 Male 3/1/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Blood Pressure Diastolic Increased Life Threatening 4/20/2005 23 Female 2/27/2006 Japan
Primary
Secondary
Loss Of Consciousness Hospitalization 51 Female 3/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Procedural Complication 11/1/2005 27 Male 3/1/2006 Other Health Professional United States
Primary
Secondary
Loss Of Consciousness Other Serious 51 Male 3/8/2006
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 51 Female 3/7/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Torsade De Pointes Other Serious 8 Male 64 lb 3/9/2006 France
Primary
Concomitant
Ventricular Tachycardia Death 2 Female 33 lb 3/10/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Death 30 Male 161 lb 3/10/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Wheezing Life Threatening 30 Male 161 lb 3/6/2006 Physician Spain
Primary
Secondary
Concomitant
Swollen Tongue 1/1/2005 32 Female 3/15/2006 Consumer United States
Primary
Secondary
Concomitant
Shock Life Threatening 4/20/2005 23 Female 3/9/2006 Japan
Primary
Secondary
Rash Erythematous Life Threatening 1/31/2006 61 Male 5/16/2006 Consumer Australia
Primary
Secondary
Respiratory Depression Required Intervention 21 Male 77 lb 5/12/2006 Physician Japan
Primary
Concomitant
Operative Haemorrhage 1/25/2006 67 Male 5/19/2006 Other Health Professional Japan
Primary
Secondary
Ventricular Tachycardia Life Threatening 47 Male 6/6/2006 Other Health Professional Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 21 Male 203 lb 6/8/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 22 Male 6/8/2006 Other Health Professional Japan
Primary
Concomitant
Drug Interaction Other Serious 59 Male 106 lb 6/12/2006 Other Health Professional Japan
Primary
Concomitant
Interacting
Skin Exfoliation Other Serious 1/20/2006 55 Male 5/29/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 71 Male 112 lb 6/14/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Procedural Complication 6/1/2005 59 Male 106 lb 6/15/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 47 Male 6/16/2006 Other Health Professional Japan
Primary
Concomitant
Post Procedural Haemorrhage 1/25/2006 67 Male 6/12/2006 Japan
Primary
Secondary
Metabolic Acidosis Other Serious 22 Male 7/5/2006 Other Health Professional Japan
Primary
Concomitant
Rash Erythematous Life Threatening 1/31/2006 61 Male 7/18/2006 Consumer Australia
Primary
Secondary
Ventricular Tachycardia Hospitalization 1/1/2006 68 Male 8/9/2006 Physician Japan
Primary
Secondary
Delayed Recovery From Anaesthesia Hospitalization 8/2/2006 67 Male 9/4/2006 Japan
Primary
Secondary
Supraventricular Extrasystoles Required Intervention 1/12/2005 55 Male 9/7/2006 Pharmacist Japan
Primary
Concomitant
Procedural Complication Hospitalization 8/2/2006 67 Male 9/22/2006 Japan
Primary
Secondary
Concomitant
Bronchospasm Life Threatening 1/13/2006 17 Female 10/18/2006 Japan
Primary
Concomitant
Thrombocytopenia Other Serious 64 Male 196 lb 10/17/2006 Other Health Professional United Kingdom
Primary
Concomitant
Urticaria Generalised Life Threatening 10/13/2006 26 Female 10/24/2006 Finland
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 70 Male 11/3/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Depression Hospitalization 78 Female 11/3/2006
Primary
Secondary
Concomitant
Tachypnoea Death 2/9/2006 78 Male 170 lb 11/6/2006 Physician
Primary
Concomitant
Movement Disorder Disability 88 Female 141 lb 11/7/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious 80 Male 11/8/2006 Japan
Primary
Concomitant
Tracheomalacia Other Serious 66 Female 106 lb 11/8/2006
Primary
Secondary
Acute Myocardial Infarction Other Serious 80 Male 11/8/2006 Japan
Primary
Concomitant
Tachycardia Other Serious 8/24/2006 58 Male 165 lb 11/9/2006 Consumer United Kingdom
Primary
Concomitant
Respiratory Failure Life Threatening 7/9/2006 76 Male 11/14/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Anaphylactic Shock 73 Female 11/9/2006 Physician Japan
Primary
Concomitant
Respiratory Failure Life Threatening 7/9/2006 76 Male 94 lb 12/4/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Post Procedural Complication Other Serious 3/1/2005 71 Male 137 lb 11/22/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 7/5/2006 Female 12/6/2006 Japan
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 4/22/2006 Male 12/18/2006 Japan
Primary
Concomitant
Respiratory Failure Life Threatening 7/9/2006 76 Male 94 lb 12/26/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Required Intervention 9/1/2006 73 Female 12/28/2006 Physician Japan
Primary
Concomitant
Drug Hypersensitivity Life Threatening 11/7/2006 26 Female 1/24/2007 Japan
Primary
Concomitant
Pharyngolaryngeal Pain Life Threatening 11/7/2006 26 Female 1/26/2007 Japan
Primary
Concomitant
Sinus Arrest Hospitalization 5/25/2006 Male 2/9/2007 Japan
Primary
Secondary
Concomitant
Tongue Oedema Hospitalization 70 Female 86 lb 2/12/2007 Other Health Professional Japan
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 5/25/2006 Male 97 lb 2/22/2007 Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 7/5/2006 Female 3/9/2007 Japan
Primary
Concomitant
Syncope Vasovagal Life Threatening 10/22/2004 64 Male 3/21/2007 Japan
Primary
Secondary
Anaphylactic Reaction Life Threatening 3/20/2007 82 Male 132 lb 4/18/2007 United Kingdom
Primary
Secondary
Arteriospasm Coronary Other Serious 70 Female 101 lb 4/24/2007 Other Health Professional Japan
Primary
Concomitant
Transient Ischaemic Attack Other Serious 12 Male 4/20/2007 Consumer United States
Primary
Secondary
Respiratory Depression Other Serious 78 Female 5/7/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Pneumonia Aspiration Hospitalization 1/1/2007 65 Female 5/16/2007 Physician Canada
Primary
Secondary
Anaphylactic Reaction Other Serious 3/26/2007 29 Female 5/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lung Disorder Other Serious 58 Male 6/28/2007 Other Health Professional Japan
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 1/1/2006 40 Female 115 lb 6/27/2007 Japan
Primary
Secondary
Lung Disorder Other Serious 58 Male 7/6/2007 Other Health Professional Japan
Primary
Concomitant
Sinus Tachycardia Life Threatening 8/18/2006 63 Male 7/9/2007 Japan
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization Male 116 lb 7/11/2007 Physician Japan
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 1/24/2005 2 Female 24 lb 11/23/2005 Physician Japan
Primary
Concomitant
Atrioventricular Block Complete Life Threatening 7/12/2007 Female 97 lb 7/24/2007 Physician Japan
Primary
Concomitant
Pulmonary Oedema Life Threatening 40 Female 161 lb 7/30/2007 United States
Primary
Concomitant
Ventricular Fibrillation Required Intervention 1 Female 9 lb 7/25/2007 Physician United States
Primary
Secondary
Tremor Required Intervention 6 Male 55 lb 7/27/2007 Physician United States
Primary
Secondary
Concomitant
Sinus Tachycardia Life Threatening 8/18/2006 63 Male 7/26/2007 Japan
Primary
Secondary
Concomitant
Atrioventricular Block Complete Life Threatening 7/12/2007 Female 97 lb 8/2/2007 Physician Japan
Primary
Concomitant
Vein Disorder Required Intervention 22 Male 8/8/2007 Physician United States
Primary
Secondary
Concomitant
Sensory Loss Required Intervention 15 Male 152 lb 8/8/2007 Physician Australia
Primary
Secondary
Concomitant
Mediastinitis Hospitalization 10/27/2006 Male 116 lb 8/10/2007 Physician Japan
Primary
Concomitant
Nephritis Interstitial Hospitalization 7/13/2007 79 Female 186 lb 8/1/2007 Other Health Professional United States
Primary
Concomitant
Device Failure 8/6/2007 69 Male 8/27/2007 United States
Primary
Secondary
Concomitant
Peritonitis Hospitalization 6/30/2007 70 Female 153 lb 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Myotonia Hospitalization 7/1/2005 55 Female 132 lb 9/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Prothrombin Level Decreased Hospitalization 5/16/2007 Male 10/26/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vertebral Injury Other Serious 9/19/2007 Male 220 lb 10/29/2007 Physician Canada
Primary
Concomitant
Postoperative Wound Infection Life Threatening 9/10/2007 Male 183 lb 10/31/2007 Physician Italy
Primary
Concomitant
Ventricular Dysfunction Required Intervention 1 Male 9 lb 11/6/2007 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 1 Male 9 lb 11/15/2007 United States
Primary
Secondary
Concomitant
Delayed Recovery From Anaesthesia Life Threatening 65 Female 106 lb 11/16/2007 Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 3/22/2007 69 Male 111 lb 11/21/2007 Japan
Primary
Secondary
Concomitant
Atrioventricular Block Complete Life Threatening 7/12/2007 Female 97 lb 12/7/2007 Physician Japan
Primary
Concomitant
Death Death 1/1/2006 21 Male 1/22/2008 United States
Primary
Secondary
Priapism Other Serious 12/12/2007 39 Male 1/25/2008 Physician Spain
Primary
Secondary
Ventricular Tachycardia Other Serious 3/22/2007 69 Male 111 lb 1/30/2008 Japan
Primary
Secondary
Concomitant
Priapism Other Serious 12/12/2007 39 Male 2/5/2008 Physician Spain
Primary
Secondary
Blood Bilirubin Increased Other Serious 2/3/2007 Male 2/8/2008 Other Health Professional Japan
Primary
Secondary
Procedural Complication Life Threatening 10/1/2007 64 Male 2/22/2008 Physician Canada
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Required Intervention 7/18/2007 74 Female 7/19/2007 Other Health Professional United States
Primary
Concomitant
Oropharyngeal Blistering Other Serious 42 Female 3/21/2008 Ireland
Primary
Secondary
Thrombocytopenia Life Threatening 2/22/2008 61 Male 3/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Oropharyngeal Blistering Other Serious Female 3/25/2008 Consumer Ireland
Primary
Secondary
Oropharyngeal Blistering Other Serious Female 3/28/2008 Consumer Ireland
Primary
Secondary
Rash Papular Other Serious 9/27/2007 49 Female 119 lb 4/1/2008 Physician Japan
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 2/3/2007 Male 4/4/2008 Other Health Professional Japan
Primary
Secondary
Potentiating Drug Interaction Other Serious 41 Female 364 lb 4/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Test Positive Required Intervention 19 Male 139 lb 4/18/2008 Physician Mexico
Primary
Secondary
Concomitant
Weight Bearing Difficulty Hospitalization 47 Male 4/24/2008 Other Health Professional Australia
Primary
Concomitant
Urinary Retention Hospitalization 4/1/2008 36 Female 161 lb 4/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperbilirubinaemia Other Serious 3/20/2008 37 Male 4/28/2008 United States
Primary
Secondary
Concomitant
Hyperbilirubinaemia Other Serious 3/20/2005 37 Male 172 lb 4/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 1/1/1998 29 Female 4/24/2008 Physician United Kingdom
Primary
Concomitant
Migraine With Aura Other Serious 15 Male 152 lb 4/30/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Deafness Neurosensory Other Serious 38 Female 5/1/2008 United States
Primary
Secondary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 5/1/2008 Lawyer United States
Primary
Concomitant
Sedation Other Serious 12/6/2005 44 Female 132 lb 5/5/2008 Physician Switzerland
Primary
Concomitant
Interacting
Sinus Tachycardia Hospitalization 7/1/2005 55 Female 132 lb 5/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Anaphylactoid Reaction Other Serious 63 Male 130 lb 5/15/2008 Physician Japan
Primary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 5/14/2008 Lawyer United States
Primary
Concomitant
Blood Bilirubin Increased Other Serious 2/3/2007 Male 5/15/2008 Other Health Professional Japan
Primary
Secondary
Pancytopenia Hospitalization 11/17/2007 Female 5/16/2008 Other Health Professional France
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 64 Male 5/16/2008
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 33 Female 5/16/2008
Primary
Secondary
Concomitant
Anaphylactoid Reaction Other Serious 63 Male 130 lb 5/19/2008 Physician Japan
Primary
Concomitant
Pleural Haemorrhage Life Threatening 8/31/2007 Male 110 lb 5/19/2008 Physician Japan
Primary
Concomitant

Drug Data