Famotidine combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 8/19/2004 21 9/12/2005 Physician United States
Primary
Concomitant
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Required Intervention 12/7/2005 56 Male 97 lb 1/20/2006 Physician Japan
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 5/24/2005 71 Female 12/6/2005 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 12/2/2005 73 Male 2/9/2006 Japan
Primary
Concomitant
Urosepsis Hospitalization 7/20/2005 66 Male 2/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 5/20/2002 56 Female 2/23/2006 Physician Japan
Primary
Concomitant
Shock Hospitalization 79 Male 2/27/2006 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 11/17/2005 Female 3/8/2006 Physician Japan
Primary
Secondary
Concomitant
Interacting
Toxic Epidermal Necrolysis Other Serious 2/8/2006 52 Female 3/1/2006 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 2/8/2006 52 Female 3/8/2006 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 2/8/2006 52 Female 3/21/2006 Physician Japan
Primary
Concomitant
Haemolysis Other Serious 89 Male 3/23/2006 Pharmacist Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 2/9/2006 52 Female 128 lb 3/24/2006 Physician Japan
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant 6/1/2004 69 Male 3/31/2006 United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 3/9/2006 52 Female 4/6/2006 Physician Czech Republic
Primary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 7/20/2005 66 Male 4/4/2006 United States
Primary
Secondary
Concomitant
Renal Failure Life Threatening 4/16/2006 68 Male 218 lb 4/19/2006 Pharmacist United States
Primary
Concomitant
Varices Oesophageal Hospitalization 3/9/2006 52 Female 4/18/2006 Other Health Professional Czech Republic
Primary
Concomitant
Loss Of Consciousness Death 2/1/2005 50 Female 135 lb 5/1/2006 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 4/12/2006 56 Male 132 lb 4/28/2006 Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Hypoaesthesia Life Threatening 5/12/2006 57 Male 104 lb 5/25/2006 Physician Japan
Primary
Concomitant
Varices Oesophageal Hospitalization 3/9/2006 52 Female 5/22/2006 Czech Republic
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 8/28/2002 76 Male 5/26/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 12/15/2005 86 Male 6/2/2006 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 11/17/2005 Female 6/7/2006 Physician Japan
Primary
Secondary
Concomitant
Interacting
Fall Hospitalization 1/1/2006 Female 6/20/2006 Consumer Australia
Primary
Concomitant
Prothrombin Time Prolonged Death 9/7/2004 74 Male 6/20/2006 Physician Japan
Primary
Concomitant
Tachypnoea Death 9/7/2004 73 Male 73 lb 6/28/2006 Physician Japan
Primary
Concomitant
Tachypnoea Death 9/7/2004 73 Male 73 lb 6/28/2006 Physician Japan
Primary
Concomitant
Suicide Attempt Other Serious 6/27/2006 53 Male 159 lb 7/13/2006 Physician Japan
Primary
Concomitant
Thrombosis In Device Death 9/7/2004 73 Male 73 lb 7/14/2006 Physician Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 2/1/2003 Female 178 lb 7/26/2006 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/17/2005 Female 7/28/2006 Physician Japan
Primary
Secondary
Concomitant
Interacting
Rash Pruritic 65 Female 247 lb 8/1/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Death 2/16/2006 70 Female 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 6/27/2006 53 Male 159 lb 8/3/2006 Physician Japan
Primary
Concomitant
Pancytopenia Hospitalization 6/30/2006 Male 8/3/2006 Other Health Professional Japan
Primary
Concomitant
Respiratory Depression Other Serious 7/12/2006 Female 120 lb 8/14/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pruritus Generalised Hospitalization 8/10/2006 Female 9/21/2006 Pharmacist Japan
Primary
Concomitant
Hypoalbuminaemia Required Intervention 1/17/2006 40 Female 106 lb 9/20/2006 Physician Japan
Primary
Concomitant
Post Procedural Complication Required Intervention 1/31/2006 37 Female 123 lb 10/4/2006 Physician Japan
Primary
Concomitant
Drug Interaction Other Serious 8/1/2005 30 Male 10/17/2006 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 8/9/2006 80 Male 215 lb 8/15/2006 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/13/2005 62 Female 190 lb 8/11/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Life Threatening 1/1/2006 62 Male 11/15/2006 Japan
Primary
Secondary
Concomitant
Large Intestinal Haemorrhage Other Serious 7/5/2006 80 Male 11/16/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Increased Life Threatening 1/1/2006 62 Male 11/28/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 4/1/2005 Female 158 lb 12/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Purulent Discharge Required Intervention 9/30/2006 60 Male 205 lb 12/10/2006 Other Health Professional United States
Primary
Concomitant
Septic Shock Life Threatening 4/10/2003 68 Male 12/13/2006 Japan
Primary
Concomitant
Iron Deficiency Anaemia Hospitalization 10/20/2004 Female 12/28/2006 Physician Japan
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/1/2006 67 Male 1/5/2007 Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 7/5/2006 80 Male 12/29/2006 Japan
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 11/20/2006 48 Female 86 lb 1/11/2007 Japan
Primary
Concomitant
Urticaria Other Serious 9/6/2006 63 Female 134 lb 1/2/2007 Pharmacist United States
Primary
Concomitant
Prothrombin Time Required Intervention 12/7/2005 56 Male 97 lb 2/14/2007 Physician Japan
Primary
Concomitant
Retroperitoneal Haemorrhage Required Intervention 10/20/2006 81 Female 168 lb 10/24/2006 United States
Primary
Secondary
Concomitant
Suicidal Behaviour Other Serious 1/1/2006 Male 170 lb 3/2/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neurological Symptom Other Serious 9/27/2005 Male 251 lb 3/12/2007 Physician United States
Primary
Concomitant
Arrhythmia Other Serious 1/30/2007 Male 143 lb 3/14/2007 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 3/5/2007 69 Female 3/21/2007 Pharmacist United States
Primary
Secondary
Concomitant
Haemorrhagic Diathesis Hospitalization 2/22/2007 Female 98 lb 4/2/2007 Other Health Professional Japan
Primary
Concomitant
Interacting
Skin Test Positive Hospitalization 1/17/2007 86 Female 4/3/2007 Physician Japan
Primary
Concomitant
Retroperitoneal Haemorrhage 10/20/2006 Female 5/1/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 5/8/2006 57 Male 86 lb 5/25/2007 Physician Japan
Primary
Concomitant
Arrhythmia Other Serious 1/30/2007 Male 143 lb 5/30/2007 Physician Japan
Primary
Concomitant
Haemorrhagic Diathesis Hospitalization 2/22/2007 Female 98 lb 6/1/2007 Other Health Professional Japan
Primary
Concomitant
Interacting
Post Procedural Complication Hospitalization Male 116 lb 7/11/2007 Physician Japan
Primary
Concomitant
Encephalopathy Life Threatening 6/2/2007 73 Male 7/31/2007 Other Health Professional Japan
Primary
Concomitant
Interstitial Lung Disease Death 6/1/2007 Male 8/2/2007 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenia Other Serious 7/9/2007 Female 104 lb 8/2/2007 Physician Japan
Primary
Concomitant
Dyspnoea Hospitalization 7/19/2007 64 Female 154 lb 8/3/2007 Other Health Professional Japan
Primary
Concomitant
Mediastinitis Hospitalization 10/27/2006 Male 116 lb 8/10/2007 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 7/23/2007 82 Male 8/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Life Threatening 6/9/2004 56 Male 8/27/2007 Physician Japan
Primary
Secondary
Hepatic Neoplasm Malignant Hospitalization 6/1/2004 Male 9/5/2007 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/9/2007 Female 104 lb 9/7/2007 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 7/23/2007 82 Male 9/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Other Serious 8/18/2007 Male 9/19/2007 Physician Japan
Primary
Concomitant
Subarachnoid Haemorrhage Life Threatening 9/9/2007 72 Female 9/26/2007 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 7/23/2007 82 Male 10/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 2/15/2005 78 Male 119 lb 10/17/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 7/31/2007 63 Male 157 lb 11/2/2007 Physician Japan
Primary
Concomitant
Fall Hospitalization 10/1/2007 Male 11/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Melaena Hospitalization 11/16/2006 77 Male 139 lb 11/23/2007 Physician Japan
Primary
Concomitant
Intraventricular Haemorrhage Hospitalization 10/2/2007 35 Male 11/16/2007 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/7/2007 63 Male 165 lb 11/26/2007 Pharmacist United States
Primary
Concomitant
Subdural Haematoma Other Serious 4/22/2007 71 Male 11/30/2007 Physician Japan
Primary
Concomitant
Oedema Peripheral Other Serious 11/11/2007 Female 208 lb 12/13/2007 Other Health Professional United States
Primary
Concomitant
Interstitial Lung Disease Death 10/1/2007 79 Male 168 lb 12/17/2007 Physician Japan
Primary
Secondary
Concomitant
Completed Suicide Other Serious 1/10/2005 Female 176 lb 12/18/2007 Physician Japan
Primary
Concomitant
Respiratory Disorder Other Serious 10/26/2007 62 Male 132 lb 1/3/2008 Physician Japan
Primary
Concomitant
Splenomegaly Death 10/1/2007 79 Male 1/2/2008 Physician Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 6/11/2007 74 Female 1/8/2008 Japan
Primary
Secondary
Concomitant
Epistaxis Other Serious 12/15/2007 Female 208 lb 1/18/2008 Other Health Professional United States
Primary
Concomitant
Treatment Noncompliance Other Serious 11/26/2007 67 Male 121 lb 1/14/2008 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 56 Female 2/15/2008 Pharmacist Japan
Primary
Concomitant
Pleural Effusion Hospitalization 2/4/2008 Male 2/18/2008 United States
Primary
Concomitant
Vasculitis Death 10/1/2007 79 Male 2/1/2008 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 1/9/2007 80 Male 2/21/2008 Physician Japan
Primary
Secondary
Concomitant
Eosinophilic Pneumonia Other Serious 2/15/2008 22 Female 2/29/2008 Physician Japan
Primary
Concomitant
Pleural Effusion Other Serious 10/26/2007 62 Male 132 lb 2/27/2008 Physician Japan
Primary
Concomitant
Pulmonary Embolism Life Threatening 2/7/2008 74 Female 3/3/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 2/7/2008 74 Female 3/5/2008 Physician Japan
Primary
Secondary
Concomitant
Swelling Face Other Serious 2/15/2008 Female 97 lb 3/14/2008 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 7/31/2007 63 Male 157 lb 3/27/2008 Physician Japan
Primary
Concomitant
Swelling Face Other Serious 2/15/2008 Female 97 lb 3/27/2008 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 2/7/2008 74 Female 3/28/2008 Physician Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening Female 4/4/2008 Pharmacist United States
Primary
Concomitant
Pleural Effusion Hospitalization 2/4/2008 Male 4/4/2008 United States
Primary
Concomitant
Death Death 1/29/2007 Male 176 lb 4/23/2008 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 7/27/2005 Male 6/2/2008 Other Health Professional France
Primary
Concomitant
Shock Disability 4/15/2008 74 Male 5/27/2008 Other Health Professional Japan
Primary
Concomitant
Retinal Haemorrhage Life Threatening 3/7/2008 Female 6/4/2008 Physician Japan
Primary
Concomitant
Interacting
Blood Lactate Dehydrogenase Increased Disability 5/20/2008 Female 128 lb 6/4/2008 Japan
Primary
Secondary
Concomitant
Protein Total Decreased Hospitalization 12/12/2007 83 Female 88 lb 6/9/2008 Physician Japan
Primary
Secondary
Concomitant
Blood Lactate Dehydrogenase Increased Disability 5/20/2008 Female 128 lb 6/25/2008 Japan
Primary
Secondary
Concomitant
Cystitis Haemorrhagic Other Serious 6/21/2008 67 Male 7/15/2008 Physician Japan
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 1/1/2005 77 Male 7/15/2008 Consumer Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 2/2/1997 53 Male 7/9/2008 Pharmacist United States
Primary
Secondary
Concomitant
Intentional Overdose Hospitalization 6/30/2008 63 Female 7/17/2008 Physician Japan
Primary
Concomitant
Retinal Haemorrhage Life Threatening 5/3/2008 Female 7/23/2008 Physician Japan
Primary
Concomitant
Interacting
Intentional Overdose Hospitalization 6/30/2008 63 Female 7/25/2008 Physician Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/21/2007 Male 8/7/2008 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 5/5/2008 Female 8/7/2008 Pharmacist United States
Primary
Concomitant
No Therapeutic Response Hospitalization 9/19/2006 68 Female 77 lb 8/22/2008 Japan
Primary
Concomitant
Shock Disability 4/15/2008 74 Male 8/21/2008 Other Health Professional Japan
Primary
Concomitant
Henoch-schonlein Purpura Hospitalization 4/27/2008 Male 8/27/2008 United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 6/1/2000 30 Male 116 lb 9/18/2008 Physician Japan
Primary
Concomitant
Small Intestinal Haemorrhage Hospitalization 11/16/2007 62 Male 143 lb 9/22/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 9/19/2006 68 Female 77 lb 9/22/2008 Physician Japan
Primary
Concomitant
Urine Bilirubin Increased Hospitalization 4/28/2008 73 Female 9/24/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/21/2007 Male 10/7/2008 Physician United States
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 11/17/2007 82 Female 127 lb 10/7/2008 Pharmacist United States
Primary
Concomitant
Catheter Site Oedema Hospitalization 7/26/2004 30 Female 132 lb 10/9/2008 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 2/18/2008 86 Male 10/10/2008 Japan
Primary
Concomitant
Pulmonary Embolism Hospitalization Female 123 lb 10/10/2008 Israel
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/27/2008 Female 123 lb 10/16/2008 Israel
Primary
Secondary
Concomitant
Weight Increased Other Serious 29 Female 120 lb 10/18/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 2/1/2005 64 Female 79 lb 10/9/2008 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Hospitalization Male 10/21/2008 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 2/18/2008 86 Male 132 lb 10/23/2008 Japan
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 11/10/2008 Pharmacist United States
Primary
Concomitant
Movement Disorder Hospitalization 8/10/2008 57 Male 11/11/2008 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Life Threatening 9/7/2008 60 Male 11/5/2008 Japan
Primary
Concomitant
Death Death 10/25/2008 Male 73 lb 11/12/2008 Japan
Primary
Concomitant
Weight Fluctuation Other Serious 29 Female 11/17/2008 Japan
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 8/1/2007 Female 160 lb 11/21/2008 Consumer United States
Primary
Concomitant

Drug Data