Etoposide combined with Novantrone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Small Intestinal Obstruction Hospitalization 11/1/2005 71 Female 2/2/2006 United States
Primary
Secondary
Concomitant
Lung Infiltration Life Threatening 11/17/2005 64 Female 2/3/2006 Germany
Primary
Secondary
Treatment Related Secondary Malignancy Life Threatening 7/2/2005 59 Male 139 lb 2/16/2006 Consumer United States
Primary
Secondary
Concomitant
Herpes Simplex Serology Positive Other Serious 6/10/2005 26 Female 182 lb 2/10/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/9/2005 64 Male 171 lb 2/10/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/27/2004 56 Female 106 lb 2/21/2006 United States
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Life Threatening 7/2/2005 59 Male 139 lb 3/8/2006 Consumer Japan
Primary
Secondary
Concomitant
Metastases To Peritoneum Life Threatening 7/2/2005 59 Male 2/28/2006 France
Primary
Secondary
Pancytopenia Life Threatening 5/13/2005 Male 3/7/2006 United States
Primary
Secondary
Therapy Non-responder Life Threatening 1/26/2006 74 Male 3/7/2006 United States
Primary
Secondary
Pancytopenia Hospitalization 1/23/2006 81 Male 160 lb 3/10/2006 United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/23/2006 81 Male 160 lb 3/17/2006 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 1/19/2006 64 Male 3/16/2006 United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 2/23/2006 53 Female 131 lb 3/28/2006 United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/23/2006 81 Male 160 lb 3/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 11/13/2004 67 Male 4/13/2006 Physician Germany
Primary
Secondary
Herpes Simplex Hospitalization 6/10/2005 26 Female 182 lb 4/19/2006 United States
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Hospitalization 9/2/2004 75 Male 4/19/2006 Germany
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 2/17/2006 55 Male 4/21/2006 United States
Primary
Secondary
Concomitant
Weight Increased Life Threatening 1/19/2006 64 Male 4/25/2006 Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/23/2006 81 Male 160 lb 4/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Infiltration Hospitalization 4/24/2005 64 Male 5/2/2006 Germany
Primary
Secondary
Lung Infiltration Hospitalization 11/20/2004 63 Male 5/3/2006 Other Health Professional Germany
Primary
Secondary
Septic Shock Death 4/24/2006 57 Male 245 lb 5/23/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/9/2006 43 Male 5/24/2006 Japan
Primary
Concomitant
Skin Necrosis Death 5/7/2006 71 Male 5/31/2006 Italy
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 4/28/2006 53 Female 5/31/2006 Physician United States
Primary
Secondary
Concomitant
Fungal Infection Death 5/7/2006 71 Male 6/6/2006 Italy
Primary
Secondary
Concomitant
Septic Shock Death 2/3/2006 71 Female 6/7/2006 Portugal
Primary
Secondary
Concomitant
Septic Shock Death 2/3/2006 71 Female 6/20/2006 Portugal
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/31/2002 60 Female 115 lb 6/20/2006 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 7/25/2004 56 Female 106 lb 6/5/2006 United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 6/4/2005 26 Female 184 lb 6/5/2006 United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/23/2006 68 Male 148 lb 6/22/2006 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 10/1/2004 67 Male 6/26/2006 Germany
Primary
Secondary
Septic Shock Hospitalization 11/13/2004 67 Male 6/30/2006 United States
Primary
Secondary
Septic Shock Death 4/24/2006 57 Male 245 lb 6/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Hospitalization 9/2/2004 75 Male 7/6/2006 Germany
Primary
Secondary
Concomitant
Staphylococcal Infection Death 2/1/2005 63 Female 7/13/2006 Italy
Primary
Secondary
Concomitant
Hypotension Life Threatening 1/10/2006 53 Female 152 lb 7/13/2006 Physician United States
Primary
Secondary
Febrile Neutropenia Hospitalization 6/21/2006 62 Male 214 lb 7/13/2006 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 3/9/2006 43 Male 7/11/2006 Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 1/1/2005 70 Male 7/13/2006 Other Health Professional Germany
Primary
Secondary
Ventricular Tachycardia Life Threatening 11/10/2005 70 Male 7/19/2006 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 2/1/2005 63 Female 154 lb 7/20/2006 United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 1/23/2006 81 Male 160 lb 7/26/2006 Physician United States
Primary
Secondary
Concomitant
Trichosporon Infection Hospitalization 4/24/2006 57 Male 245 lb 8/1/2006 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/21/2006 62 Male 214 lb 8/1/2006 United States
Primary
Secondary
Weight Increased Life Threatening 12/1/2004 62 Male 160 lb 8/10/2006 United States
Primary
Secondary
Pneumonia Hospitalization 5/23/2006 68 Male 148 lb 8/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 2/25/2006 59 Male 160 lb 8/14/2006 United States
Primary
Secondary
Concomitant
Weight Increased Life Threatening 12/21/2004 62 Male 8/17/2006 United States
Primary
Secondary
Stomatitis Hospitalization 1/23/2006 81 Male 160 lb 8/30/2006 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 8/2/2006 67 Male 9/6/2006
Primary
Secondary
Concomitant
Weight Increased Life Threatening 12/1/2004 62 Male 160 lb 9/8/2006 United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 8/8/2006 70 Female 164 lb 9/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Life Threatening 12/21/2004 62 Male 9/14/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 1/15/2006 59 Male 9/19/2006 Japan
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 5/23/2006 68 Male 148 lb 9/22/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/30/2006 59 Male 9/26/2006 Japan
Primary
Secondary
Concomitant
Ventricular Failure Hospitalization 4/28/2006 53 Female 185 lb 9/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 9/18/2006 66 Female 10/12/2006 United States
Primary
Secondary
Concomitant
Klebsiella Sepsis Life Threatening 9/4/2005 73 Male 10/25/2006 Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/10/2006 63 Male 10/30/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/3/2004 68 Female 10/31/2006 Germany
Primary
Secondary
Concomitant
Head Injury Death 10/20/2006 73 Male 11/9/2006 United States
Primary
Secondary
Ventricular Fibrillation Life Threatening 9/18/2006 66 Female 11/17/2006 Italy
Primary
Secondary
Concomitant
Ventricular Flutter Life Threatening 2/27/2006 20 Female 11/21/2006 Japan
Primary
Concomitant
Therapy Non-responder Life Threatening 11/7/2006 77 Male 155 lb 11/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 4/15/2006 73 Male 11/30/2006 Physician Japan
Primary
Secondary
Concomitant
Head Injury Death 10/20/2006 73 Male 12/5/2006 United States
Primary
Concomitant
Septic Shock Death 11/18/2006 62 Male 12/6/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Cardio-respiratory Arrest Death 10/20/2006 75 Male 12/6/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Lung Infiltration Hospitalization 4/24/2005 64 Male 12/12/2006 Germany
Primary
Secondary
Thrombocytopenia Life Threatening 5/3/2004 68 Female 12/12/2006 Germany
Primary
Secondary
Lung Infiltration Hospitalization 11/20/2004 63 Male 12/12/2006 United States
Primary
Secondary
Septic Shock Death 11/18/2006 62 Male 12/21/2006 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 8/2/2006 67 Male 12/22/2006 United States
Primary
Secondary
Concomitant
Klebsiella Sepsis Life Threatening 9/4/2005 73 Male 12/22/2006 Netherlands
Primary
Secondary
Concomitant
Renal Failure Other Serious 7/3/2006 71 Male 1/12/2007 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/6/2007 67 Male 1/22/2007 United States
Primary
Secondary
Transaminases Increased Hospitalization 4/28/2006 53 Female 185 lb 2/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Hospitalization 2/18/2006 55 Male 2/5/2007 United States
Primary
Secondary
Concomitant
Fungal Infection Death 6/25/2006 65 Male 2/8/2007 Germany
Primary
Secondary
Small Intestinal Obstruction Hospitalization 11/1/2005 71 Female 108 lb 2/14/2007 United States
Primary
Secondary
Concomitant
Lacunar Infarction Hospitalization 8/8/2006 70 Female 164 lb 2/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Flutter Other Serious 2/27/2006 Female 95 lb 3/5/2007 Physician Japan
Primary
Secondary
Concomitant
Septic Shock Other Serious 2/18/2007 67 Female 3/5/2007 Italy
Primary
Secondary
Concomitant
Septic Shock Hospitalization 2/17/2007 69 Male 3/8/2007 Belgium
Primary
Secondary
Sepsis Life Threatening 1/1/2005 Male 183 lb 3/20/2007 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/16/2006 20 Female 3/13/2007 Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 7/3/2006 71 Male 3/15/2007 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/6/2007 67 Male 3/19/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1/6/2007 67 Male 3/20/2007 Other Health Professional United States
Primary
Secondary
Systemic Mycosis Life Threatening 3/10/2007 67 Male 3/23/2007 Physician United States
Primary
Secondary
Weight Increased Other Serious 4/1/2006 35 Male 3/26/2007 United States
Primary
Secondary
Concomitant
Pulmonary Infarction Death 12/2/2004 63 Female 3/27/2007 United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 1/1/2005 70 Male 3/27/2007 United States
Primary
Secondary
Septic Shock Life Threatening 11/18/2006 62 Male 3/27/2007 United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 5/3/2004 68 Female 3/28/2007 United States
Primary
Secondary
Torsade De Pointes Life Threatening 3/8/2007 66 Female 116 lb 3/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 2/16/2005 71 Female 4/2/2007 Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2/1/2005 63 Female 154 lb 4/2/2007 Italy
Primary
Secondary
Concomitant
Supraventricular Tachycardia Life Threatening 3/10/2007 67 Male 4/6/2007 Other Health Professional United States
Primary
Secondary
Pseudomembranous Colitis Other Serious 10/30/2006 Male 161 lb 4/17/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Life Threatening 1/10/2007 65 Male 4/13/2007 Italy
Primary
Secondary
Sepsis Death 9/23/2006 72 Male 4/26/2007 Germany
Primary
Secondary
Sepsis Death 3/19/2007 67 Male 4/26/2007 Italy
Primary
Secondary
Concomitant
Fungal Infection Death 6/25/2005 65 Male 4/26/2007 Germany
Primary
Secondary
Myocardial Infarction Death 6/26/2005 70 Male 5/1/2007 Germany
Primary
Secondary
Concomitant
Sepsis Other Serious 4/9/2007 42 Male 140 lb 5/4/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 4/22/2007 55 Female 185 lb 5/14/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 4/9/2007 42 Male 140 lb 5/21/2007 Other Health Professional United States
Primary
Secondary
Respiratory Failure Life Threatening 6/23/2006 74 Male 6/7/2007 Belgium
Primary
Secondary
Pseudomembranous Colitis Other Serious 10/30/2006 Male 161 lb 6/15/2007 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Life Threatening 4/13/2007 70 Male 6/18/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Life Threatening 1/10/2007 65 Male 6/14/2007 Italy
Primary
Secondary
Pneumonia Life Threatening 5/21/2007 22 Male 6/18/2007 United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 5/22/2007 64 Male 187 lb 6/20/2007 Other Health Professional United States
Primary
Secondary
Metastasis Life Threatening 4/13/2007 70 Male 6/19/2007 Physician France
Primary
Secondary
Concomitant
Pseudomembranous Colitis Other Serious 11/17/2006 45 Male 6/25/2007 Japan
Primary
Secondary
Concomitant
Transitional Cell Carcinoma Life Threatening 4/13/2007 70 Male 6/28/2007 Physician France
Primary
Secondary
Concomitant
Bladder Cancer Life Threatening 4/13/2007 70 Male 7/9/2007 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/23/2006 74 Male 7/5/2007 Belgium
Primary
Secondary
Concomitant
Sepsis Death 9/23/2006 72 Male 7/6/2007 Other Health Professional Germany
Primary
Secondary
Myocardial Infarction Death 6/26/2005 70 Male 7/9/2007 United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Life Threatening 3/10/2007 67 Male 7/11/2007 Other Health Professional United States
Primary
Secondary
Vision Blurred Life Threatening 4/28/2006 65 Male 7/13/2007 United States
Primary
Secondary
Enterococcal Infection Hospitalization 1/10/2006 72 Male 7/13/2007 United States
Primary
Secondary
Septic Shock Death 6/30/2007 69 Male 7/16/2007 United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/23/2006 74 Male 7/23/2007 United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 1/10/2007 65 Male 7/27/2007 Italy
Primary
Secondary
Respiratory Failure Life Threatening 6/23/2006 74 Male 8/3/2007 Belgium
Primary
Secondary
Concomitant
Encephalitis Death 7/18/2007 72 Male 8/9/2007 Italy
Primary
Secondary
Encephalitis Death 7/18/2007 72 Male 8/13/2007 Other Health Professional Italy
Primary
Secondary
Septic Shock Death 6/30/2007 69 Male 8/15/2007 Italy
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 3/8/2007 66 Female 116 lb 8/16/2007 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 7/13/2007 53 Male 8/17/2007 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Life Threatening 7/1/2007 53 Male 8/27/2007 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 4/22/2007 55 Female 185 lb 8/29/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 3/19/2007 67 Male 8/31/2007 Italy
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/8/2006 36 Female 9/19/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 1/1/2007 60 Male 123 lb 9/27/2007 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 11/8/2006 36 Female 11/2/2007 Japan
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 11/13/2006 70 Male 11/2/2007 Italy
Primary
Secondary
Concomitant
Enterococcal Infection Hospitalization 1/10/2006 72 Male 11/14/2007 Germany
Primary
Secondary
Sepsis Death 46 Female 11/21/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 5/10/2007 67 Female 11/19/2007 Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/19/2007 67 Male 11/30/2007 Italy
Primary
Secondary
Concomitant
Cardiopulmonary Failure Death 7/8/2007 69 Female 12/6/2007 United States
Primary
Secondary
Concomitant

Drug Data