Etoposide combined with Mercaptopurine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Chromosome Abnormality Other Serious 3/27/2006 Consumer Japan
Primary
Concomitant
Urinary Incontinence Disability 18 Male 3/15/2006
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 55 Female 6/16/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Torsade De Pointes Required Intervention 55 Female 6/29/2006 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 55 Female 7/7/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Metastasis Other Serious 3 Male 7/25/2006 Physician Turkey
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious 13 Female 7/25/2006 Physician Turkey
Primary
Secondary
Primitive Neuroectodermal Tumour Death 10 Male 7/25/2006 Physician Turkey
Primary
Secondary
Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Staphylococcal Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Enterobacter Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Bacterial Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious 3 Male 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Death 10 Male 8/3/2006 Consumer United States
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious 13 Female 8/3/2006 Consumer United States
Primary
Secondary
Xerosis Hospitalization 11 Male 6/13/2007 Physician United States
Primary
Concomitant
Wound Abscess Hospitalization 6/6/2007 Male 45 lb 6/21/2007 United States
Primary
Secondary
Acute Myeloid Leukaemia Life Threatening 9 Female 9/10/2007 Argentina
Primary
Secondary
Rash Other Serious 45 Female 9/20/2007 Other Health Professional Germany
Primary
Secondary
Post Procedural Complication Hospitalization 14 Male 9/19/2007 Japan
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 11 Male 10/30/2007 Physician United States
Primary
Concomitant
Systemic Candida Other Serious 26 Male 11/8/2007 Other Health Professional Germany
Primary
Secondary
Systemic Candida Hospitalization 26 Male 11/15/2007 Germany
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 11/21/2007 Germany
Primary
Secondary
Concomitant
Systemic Candida Hospitalization 26 Male 12/19/2007 Germany
Primary
Secondary
Splenomegaly Other Serious 4 Female 3/15/2008 Physician United States
Primary
Secondary
Lymphoproliferative Disorder Other Serious 4 Female 3/20/2008 United States
Primary
Secondary
Splenomegaly Death 4 Female 3/24/2008 Other Health Professional United States
Primary
Secondary
Viral Dna Test Positive Other Serious 4 Female 3/19/2008 Physician United States
Primary
Secondary
Ewing's Sarcoma Other Serious 16 Male 3/31/2008
Primary
Secondary
Concomitant
Sinusitis Fungal Other Serious Female 3/31/2008 Physician United States
Primary
Secondary
Lymphoproliferative Disorder Hospitalization 1/1/2005 3 Female 5/9/2008 Physician United States
Primary
Secondary
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Malignant Histiocytosis Other Serious 1 Male 6/20/2008 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Life Threatening 54 Male 6/26/2008 United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 6/30/2008 Consumer United States
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/9/2008 Consumer United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/15/2008 United Kingdom
Primary
Secondary
Neoplasm Malignant Life Threatening 54 Male 7/16/2008 United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/17/2008 Consumer United Kingdom
Primary
Secondary
Neoplasm Malignant Life Threatening 54 Male 7/17/2008 United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Neoplasm Malignant Life Threatening 54 Male 7/25/2008 United Kingdom
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/28/2008 United Kingdom
Primary
Secondary
Promyelocyte Count Increased Life Threatening 54 Male 7/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Transient Ischaemic Attack Hospitalization 7/22/2008 9 Male 76 lb 8/8/2008 Physician United States
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Life Threatening 54 Male 8/18/2008 Other Health Professional United Kingdom
Primary
Secondary
Sinusitis Other Serious 4/1/2002 Male 9/15/2008 Consumer France
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Other Serious 54 Male 9/29/2008 United Kingdom
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 1 Male 10/16/2008
Primary
Secondary
Sinusitis Other Serious 4/1/2002 Male 11/24/2008 Consumer France
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Life Threatening 54 Male 8/15/2008 United Kingdom
Primary
Secondary
Sinusitis Other Serious 4/1/2002 12/17/2008 Other Health Professional France
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3/24/2008 5 Male 47 lb 3/25/2009 Physician Japan
Primary
Secondary
Concomitant
Pneumatosis Intestinalis Hospitalization 1/5/2009 1 Female 15 lb 3/30/2009 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/5/2009 1 Female 15 lb 3/27/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2009 1 Female 15 lb 4/13/2009 Physician
Primary
Secondary
Concomitant
Vomiting Other Serious 9 5/8/2009 Other Health Professional Japan
Primary
Secondary
Lactobacillus Infection Hospitalization 5/3/2009 1 Male 5/15/2009 Physician
Primary
Secondary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 5/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Lactobacillus Infection Hospitalization 5/3/2009 1 Male 20 lb 6/1/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/21/2008 Male 47 lb 10/9/2009 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 12/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 1/4/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Other Serious 17 Male 1/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Other Serious 54 Male 1/8/2010 Consumer United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 1/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 1/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Renal Impairment Other Serious 17 Male 1/26/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 1/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 1/22/2010 Thailand
Primary
Secondary
Renal Impairment Other Serious 17 Male 2/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenia Hospitalization 14 Male 2/25/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 3/22/2010 9 Female 57 lb 5/20/2010 Consumer United States
Primary
Secondary
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Treatment Failure Other Serious 13 Male 8/26/2010
Primary
Secondary
Tachycardia Other Serious 9/20/2007 50 Male 194 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis B Other Serious 57 Female 9/9/2010 Other Health Professional Turkey
Primary
Secondary
Hepatitis B Surface Antigen Positive Required Intervention 57 Female 9/17/2010 Other Health Professional Turkey
Primary
Secondary
Concomitant
Hepatitis B Other Serious 57 Female 9/28/2010 Physician Turkey
Primary
Secondary
Testicular Failure Primary Required Intervention 7 Male 10/1/2010 Physician United States
Primary
Secondary
Hepatitis B Hospitalization 57 Female 9/30/2010 Turkey
Primary
Secondary
White Blood Cell Count Decreased Hospitalization Male 10/26/2010
Primary
Secondary
Pulmonary Fibrosis Other Serious 27 Male 11/15/2010 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Pulmonary Fibrosis Other Serious 5/1/2008 27 Male 11/21/2010 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Therapeutic Response Decreased Hospitalization 5/1/2008 27 Male 11/30/2010
Primary
Secondary
Headache Other Serious 9/1/2007 50 Male 194 lb 1/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Multi-organ Failure Death 5/28/2010 54 Female 132 lb 1/26/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Fungal Infection Other Serious Male 2/15/2011 Other Health Professional Brazil
Primary
Secondary
Renal Impairment Other Serious 17 Male 2/17/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 121 Male 2/9/2011 Physician United States
Primary
Secondary
Liver Abscess Other Serious 12 Male 2/28/2011 Other Health Professional Brazil
Primary
Secondary
Acute Graft Versus Host Disease Other Serious 3 Male 3/1/2011 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious 17 Male 3/7/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 17 Male 3/9/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 17 Male 3/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Infection Hospitalization 11/2/2010 18 Male 124 lb 5/13/2011 Physician United States
Primary
Secondary
Vomiting Life Threatening 5/5/2011 27 Male 5/18/2011 Physician Spain
Primary
Concomitant
Subdural Haematoma Life Threatening 5/5/2011 27 Male 6/9/2011 Physician Spain
Primary
Concomitant
Pneumonia Death 4 Male 9/7/2011 Other Health Professional China
Primary
Secondary
Myocardial Fibrosis Disability 1/1/2000 11 Male 77 lb 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Polycythaemia Vera Other Serious 9/1/2009 71 Male 10/18/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Polycythaemia Vera Other Serious 9/1/2009 71 Male 10/18/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Myeloproliferative Disorder Other Serious 71 Male 10/18/2011 Physician Italy
Primary
Secondary
Polycythaemia Vera Other Serious 71 Male 10/27/2011 Other Health Professional Italy
Primary
Secondary
Enterocolitis Infectious Hospitalization 6/17/2011 22 Female 11/10/2011 Physician United States
Primary
Secondary
Headache Hospitalization 6/1/2011 22 Female 11/10/2011 Physician United States
Primary
Secondary
Dehydration Hospitalization 5/26/2011 15 Male 123 lb 11/21/2011 Consumer United States
Primary
Secondary
Oral Pain Hospitalization 5/26/2011 15 Male 11/29/2011 Physician United States
Primary
Secondary
Pancreatitis Hospitalization 12/15/2011 9 Male 69 lb 12/16/2011 United States
Primary
Secondary
Aspartate Aminotransferase Increased Other Serious 5/23/2011 5 Female 44 lb 1/31/2012 Consumer United States
Primary
Secondary
Pruritus Hospitalization 1/11/2012 23 Female 130 lb 2/17/2012 Other Health Professional United States
Primary
Secondary
Nervous System Disorder Death 4/21/2011 16 Male 95 lb 2/17/2012 Physician Japan
Primary
Secondary
Concomitant
Post Transplant Lymphoproliferative Disorder Hospitalization 1/12/2012 48 Female 130 lb 3/9/2012 Consumer Netherlands
Primary
Secondary
Nervous System Disorder Death 4/21/2011 16 Male 95 lb 3/15/2012 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/12/2012 48 Female 130 lb 3/16/2012 Physician Netherlands
Primary
Secondary
Pneumonia Lipoid Death 0 Male 3/19/2012 Other Health Professional United States
Primary
Secondary
Pain In Extremity Other Serious 3/13/2012 10 Female 46 lb 3/29/2012 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Other Serious 69 Female 3/30/2012 Other Health Professional Japan
Primary
Concomitant
Leukoencephalopathy Other Serious 17 Female 4/2/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Subileus Other Serious 17 Female 4/3/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 17 Female 4/3/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Subileus Other Serious 17 Female 4/3/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Subileus Other Serious 17 Female 4/3/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Cardiac Failure Death 2/18/2009 10 Female 44 lb 4/5/2012 Consumer Japan
Primary
Secondary
Concomitant
Subileus Other Serious 17 Female 4/8/2012 Other Health Professional Japan
Primary
Secondary
Hyperglycaemia Other Serious 17 Female 4/9/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Interacting
Vaginal Cancer Hospitalization Female 4/15/2012 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Vaginal Cancer Hospitalization Female 4/15/2012 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Vaginal Cancer Hospitalization Female 4/15/2012 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Vaginal Cancer Hospitalization Female 4/15/2012 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Rash Other Serious 17 Female 4/17/2012 Other Health Professional Japan
Primary
Secondary
Vaginal Cancer Hospitalization Female 4/18/2012 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Post Transplant Lymphoproliferative Disorder Hospitalization 1/12/2012 48 Female 130 lb 4/20/2012 Consumer Netherlands
Primary
Secondary
Vaginal Cancer Other Serious 4/1/1996 60 Female 4/20/2012 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Leukoencephalopathy Other Serious 17 Female 4/24/2012 Consumer Japan
Primary
Secondary
Septic Shock Other Serious Male 4/25/2012 Physician United States
Primary
Concomitant
Sepsis Hospitalization 7/18/2011 8 Male 5/4/2012 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 55 Female 5/1/2012 Other Health Professional United Kingdom
Primary
Concomitant
Hyperglycaemia Other Serious 5/16/2012 Other Health Professional Thailand
Primary
Secondary
Concomitant
Off Label Use Death 5/16/2012 Other Health Professional Thailand
Primary
Secondary
Concomitant
Bacterial Infection Death 5/18/2012 Other Health Professional Thailand
Primary
Secondary
Concomitant
Off Label Use Other Serious 5/24/2012 Other Health Professional Thailand
Primary
Secondary
Concomitant
Treatment Failure Other Serious 5/24/2012 Other Health Professional Thailand
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Other Serious 5/24/2012 Other Health Professional Thailand
Primary
Secondary
Concomitant

Drug Data