Etoposide combined with Melphalan

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Stem Cell Transplant Life Threatening 12/16/2005 31 Male 1/3/2006 Other Health Professional Germany
Primary
Concomitant
Urine Output Decreased Death 12/19/2005 Female 26 lb 1/12/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 12/16/2005 31 Male 1/20/2006 Other Health Professional Germany
Primary
Concomitant
Urine Output Decreased Other Serious 1/20/2006 Male 29 lb 1/23/2006 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 10/4/2005 51 Female 2/1/2006 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Female 2/2/2006 Physician Germany
Primary
Concomitant
Rash Hospitalization 1/12/2006 Female 117 lb 2/15/2006 Physician Portugal
Primary
Concomitant
Oesophagitis Other Serious 2/6/2006 Female 30 lb 2/10/2006 United States
Primary
Secondary
Concomitant
Stem Cell Transplant Required Intervention 2/7/2006 Male 41 lb 2/13/2006 United States
Primary
Secondary
Iatrogenic Injury Hospitalization 12/13/2005 52 Male 146 lb 2/17/2006 Other Health Professional Germany
Primary
Concomitant
Stem Cell Transplant Required Intervention 2/7/2006 Male 41 lb 2/15/2006 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 2/7/2006 56 Female 2/22/2006 Other Health Professional Germany
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/16/2005 31 Male 3/8/2006 Other Health Professional Germany
Primary
Concomitant
Pyrexia Hospitalization 47 Male 3/23/2006 Consumer Germany
Primary
Concomitant
Stem Cell Transplant Life Threatening 12/21/2005 63 Female 163 lb 3/20/2006 Germany
Primary
Concomitant
Weight Increased Other Serious 10/13/2005 Female 214 lb 3/27/2006 Physician Portugal
Primary
Concomitant
Rash Generalised Hospitalization 1/13/2006 59 Female 3/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
Skin Oedema Other Serious 1/17/2006 Female 282 lb 3/28/2006 Physician Portugal
Primary
Secondary
Concomitant
Rash Hospitalization 2/12/2006 34 Male 139 lb 3/28/2006 Other Health Professional France
Primary
Concomitant
Oesophagitis Other Serious 10/4/2005 51 Female 3/24/2006 Physician United States
Primary
Concomitant
Osteonecrosis Other Serious 11/9/2005 65 Female 95 lb 4/7/2006 Physician Germany
Primary
Concomitant
Venous Thrombosis Limb Hospitalization 2/12/2006 34 Male 139 lb 4/18/2006 Other Health Professional France
Primary
Concomitant
Stem Cell Transplant Hospitalization 1/13/2006 59 Female 4/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/16/2005 31 Male 4/11/2006 Other Health Professional France
Primary
Concomitant
Renal Failure Acute Life Threatening 3/14/2006 44 Female 198 lb 4/11/2006 Other Health Professional France
Primary
Concomitant
Stem Cell Transplant Life Threatening 3/10/2006 59 Female 181 lb 4/12/2006 Other Health Professional Belgium
Primary
Concomitant
Weight Increased Other Serious 10/13/2005 Female 214 lb 5/5/2006 Physician Portugal
Primary
Concomitant
Skin Oedema Other Serious 1/17/2006 Female 282 lb 5/5/2006 Physician Portugal
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 3/14/2006 44 Female 198 lb 5/10/2006 Other Health Professional France
Primary
Concomitant
Renal Failure Acute Life Threatening 3/14/2006 44 Female 198 lb 5/18/2006 France
Primary
Concomitant
Melaena Other Serious 60 Female 5/22/2006 Australia
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 1/7/2005 3 Female 5/24/2006 Spain
Primary
Concomitant
Death Death 38 Male 5/25/2006 Korea, Democratic People's Republic Of
Primary
Secondary
Pyrexia Hospitalization 11/11/2005 Male 123 lb 6/13/2006 Physician Belgium
Primary
Concomitant
Anastomotic Complication Hospitalization 3/11/2006 Unknown 6/13/2006 Other Health Professional Germany
Primary
Concomitant
Pneumonia Required Intervention 64 Male 6/16/2006 Physician Germany
Primary
Concomitant
Pseudomonal Sepsis Hospitalization 3/11/2002 66 Female 6/20/2006 Physician Spain
Primary
Concomitant
Vomiting Hospitalization 4/24/2006 47 Female 159 lb 6/21/2006 Other Health Professional France
Primary
Concomitant
Stem Cell Transplant Hospitalization 5/22/2006 60 Male 6/22/2006 Physician France
Primary
Concomitant
Viraemia Hospitalization 6/7/2006 Male 28 lb 6/14/2006 United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 5/2/2006 Female 32 lb 6/14/2006 United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 12/13/2005 52 Male 146 lb 6/27/2006 Other Health Professional France
Primary
Concomitant
Respiratory Disorder Life Threatening 5/16/2006 Male 33 lb 6/13/2006 Pharmacist United States
Primary
Secondary
No Adverse Drug Effect Hospitalization 3/11/2006 Unknown 6/23/2006 Other Health Professional Norway
Primary
Concomitant
Respiratory Failure Hospitalization 5/22/2006 60 Male 7/13/2006 Physician France
Primary
Concomitant
Wound Debridement Other Serious 1/1/2003 61 Male 187 lb 7/21/2006 Physician Germany
Primary
Concomitant
Stem Cell Transplant Hospitalization 1/9/2006 63 Female 7/17/2006 Other Health Professional Belgium
Primary
Concomitant
Stem Cell Transplant Life Threatening 3/14/2006 44 Female 198 lb 7/21/2006 Other Health Professional France
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/21/2005 63 Female 163 lb 7/21/2006 Physician Germany
Primary
Concomitant
Tongue Ulceration Other Serious 6/30/2006 Male 181 lb 8/7/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Rash Hospitalization 11/11/2005 Male 123 lb 8/11/2006 Physician Belgium
Primary
Concomitant
Tongue Ulceration Other Serious 6/30/2006 Male 181 lb 8/14/2006 Physician Canada
Primary
Secondary
Concomitant
Tachycardia Hospitalization 11/25/2005 Male 8/16/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/1/2005 62 Female 179 lb 8/22/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/22/2006 60 Male 9/25/2006 Physician France
Primary
Concomitant
Septic Shock Death 10/2/2006 Consumer France
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 10/2/2006 Consumer France
Primary
Secondary
Concomitant
Thrombophlebitis Other Serious 1/1/2005 51 Male 10/3/2006 Consumer United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 7/1/2006 Female 165 lb 10/9/2006 Physician Belgium
Primary
Concomitant
Fatigue Other Serious 9/8/2006 43 Female 9/26/2006 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 9/15/2006 59 Male 10/9/2006 Other Health Professional Switzerland
Primary
Concomitant
Stem Cell Transplant Hospitalization 9/15/2006 59 Male 10/17/2006 Other Health Professional Switzerland
Primary
Concomitant
Neutropenic Colitis Hospitalization 5/4/2006 Male 229 lb 11/6/2006 Physician Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 6/29/2006 62 Male 146 lb 11/7/2006 France
Primary
Concomitant
Pyrexia Hospitalization 8/2/2006 62 Male 143 lb 11/7/2006 France
Primary
Concomitant
Tachycardia Other Serious 9/25/2006 Male 11/20/2006 Physician Spain
Primary
Concomitant
Platelet Count Decreased Hospitalization 8/2/2006 62 Male 143 lb 11/14/2006 Physician France
Primary
Concomitant
Renal Failure Acute Hospitalization 6/29/2006 62 Male 146 lb 11/14/2006 Physician France
Primary
Concomitant
Stomatitis Other Serious 7/12/2006 Female 165 lb 12/12/2006 Physician Belgium
Primary
Concomitant
Vomiting Life Threatening 1/1/2006 Male 229 lb 12/15/2006 Physician Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 8 Male 12/12/2006 Physician Sweden
Primary
Concomitant
Viral Infection Hospitalization 6/11/2006 59 Female 179 lb 1/3/2007 Other Health Professional Belgium
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 4 Female 1/19/2007 Other Health Professional Belgium
Primary
Secondary
Pulmonary Toxicity Other Serious 9/25/2006 Male 1/22/2007 Physician Spain
Primary
Concomitant
Transient Ischaemic Attack Other Serious 10/17/2006 NotSpecified 1/19/2007 Other Health Professional Norway
Primary
Concomitant
Tenderness Other Serious 4 Female 1/26/2007
Primary
Secondary
Malnutrition Life Threatening 7/13/2006 55 Female 104 lb 1/25/2007 Other Health Professional France
Primary
Concomitant
Pyrexia Hospitalization 9/15/2006 59 Male 1/26/2007 Other Health Professional Switzerland
Primary
Concomitant
Transient Ischaemic Attack Other Serious 10/17/2006 1/29/2007 Physician Germany
Primary
Secondary
Stem Cell Transplant Death 4 Female 1/26/2007 Belgium
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 8/4/2005 59 Male 154 lb 2/5/2007 France
Primary
Concomitant
Stem Cell Transplant Death 4 Female 2/7/2007 Belgium
Primary
Secondary
Vomiting Life Threatening 5/4/2006 42 Male 229 lb 2/20/2007 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 1/29/2007 33 Female 2/14/2007 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Rash Erythematous Female 2/27/2007 Pharmacist United States
Primary
Concomitant
Haemodialysis Hospitalization 12/22/2006 68 Female 2/21/2007 Physician Germany
Primary
Concomitant
Testicular Swelling Hospitalization 2/23/2007 69 Male 176 lb 2/27/2007 Other Health Professional United States
Primary
Secondary
Respiratory Failure Hospitalization 1/29/2007 33 Female 2/27/2007 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Systemic Candida Other Serious 45 Female 3/5/2007 Japan
Primary
Concomitant
Splenic Infarction Hospitalization 9/1/2006 42 Female 3/2/2007 Other Health Professional France
Primary
Concomitant
Spinal Compression Fracture Other Serious 8/18/2006 68 Male 176 lb 3/7/2007 Physician United States
Primary
Secondary
Concomitant
Hepatocellular Damage Hospitalization 12/22/2006 68 Female 3/8/2007 Physician Germany
Primary
Concomitant
Pruritus Hospitalization 10/1/2005 Female 183 lb 3/19/2007 Netherlands
Primary
Secondary
Concomitant
Septic Shock Death 3/19/2007 Consumer Italy
Primary
Secondary
Malignant Neoplasm Progression Other Serious 4/3/2007 Other Health Professional Czech Republic
Primary
Secondary
Vomiting Other Serious 4/5/2007 Other Health Professional United States
Primary
Secondary
Mucosal Inflammation Other Serious 51 Male 4/24/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Venous Stent Insertion Other Serious 1/1/1971 Female 106 lb 5/15/2007 Physician Germany
Primary
Secondary
Concomitant
Spherocytic Anaemia Other Serious 41 Female 5/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Autoimmune Thrombocytopenia Other Serious 41 Female 5/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Disorder Death 7 Female 5/24/2007 Physician Italy
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious 7 Female 5/30/2007 Physician Italy
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious 9/20/2006 Male 6/8/2007 Physician Spain
Primary
Concomitant
Acute Myeloid Leukaemia Death 15 Male 6/11/2007 Consumer Japan
Primary
Secondary
Concomitant
Venous Stent Insertion Other Serious 1/1/1971 Female 106 lb 6/18/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 12/22/2006 68 Female 7/3/2007 Physician Germany
Primary
Concomitant
Tachycardia Other Serious 9/20/2006 Male 7/30/2007 Physician Spain
Primary
Concomitant
Renal Tubular Disorder Other Serious 7 Female 8/14/2007 Physician Italy
Primary
Secondary
Concomitant
Rash Other Serious 3 Female 8/14/2007 Consumer Czech Republic
Primary
Secondary
Rash Other Serious 4 Female 8/14/2007 Consumer Czech Republic
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 9/1/2006 42 Female 8/17/2007 Other Health Professional France
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/11/2006 59 Female 179 lb 8/21/2007 Other Health Professional Belgium
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 3/10/2006 59 Female 181 lb 8/21/2007 Other Health Professional Belgium
Primary
Concomitant
Rash Papular Other Serious 3 Female 8/27/2007 Consumer Czech Republic
Primary
Secondary
Herpes Zoster Other Serious 42 Female 8/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 9/14/2007 Consumer United States
Primary
Secondary
Pyrexia Other Serious 2/1/2007 Male 9/14/2007 Other Health Professional France
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/31/2006 55 Female 128 lb 9/21/2007 Other Health Professional
Primary
Concomitant
Hyperkeratosis Other Serious 42 Female 9/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/7/2007 Male 183 lb 9/28/2007 Pharmacist Australia
Primary
Concomitant
West Nile Viral Infection Other Serious 8/18/2006 68 Male 176 lb 9/26/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/7/2007 Male 183 lb 10/10/2007 Pharmacist Australia
Primary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/15/2007 Consumer Switzerland
Primary
Secondary
Herpes Zoster Other Serious 42 Female 10/15/2007 Other Health Professional United Kingdom
Primary
Secondary
Renal Tubular Acidosis Life Threatening 1/5/2007 Male 10/15/2007 Physician Ireland
Primary
Secondary
Concomitant
Ureaplasma Infection Other Serious 28 Male 10/15/2007 Switzerland
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 28 Male 10/17/2007
Primary
Secondary
Concomitant
Pyrexia Hospitalization 2/1/2007 Male 10/19/2007 Other Health Professional France
Primary
Concomitant
Lung Infiltration Death 7/13/2005 Female 159 lb 10/19/2007 Consumer France
Primary
Secondary
Concomitant
Ureaplasma Infection Hospitalization 28 Male 10/11/2007 Switzerland
Primary
Secondary
Myelodysplastic Syndrome Death 10/25/2007 Physician Italy
Primary
Secondary
Concomitant
Pneumonia Death 10/25/2007 Physician Italy
Primary
Secondary
Concomitant
Renal Tubular Acidosis Life Threatening 1/5/2007 Male 10/26/2007 Physician Ireland
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious Male 10/31/2007 Physician Spain
Primary
Concomitant
Weight Decreased Life Threatening 7/13/2006 55 Female 104 lb 11/8/2007 Other Health Professional France
Primary
Concomitant
Thrombocytopenia Life Threatening 12/21/2005 63 Female 163 lb 11/8/2007 Physician Germany
Primary
Concomitant
Venous Stent Insertion Other Serious 1/1/1994 Female 106 lb 11/20/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Venous Stent Insertion Other Serious 1/1/1994 Female 106 lb 11/20/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Encephalopathy Other Serious 70 Male 11/21/2007 Other Health Professional Italy
Primary
Secondary
Ureaplasma Infection Other Serious 28 Male 11/23/2007 Physician Switzerland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/22/2006 60 Male 11/16/2007 Physician France
Primary
Concomitant
Lung Infection Pseudomonal Other Serious 1/18/2007 57 Female 12/17/2007 Consumer United States
Primary
Secondary
Deafness Disability 4/3/2007 Male 12/28/2007 Physician United Kingdom
Primary
Secondary
Deafness Disability 4/3/2007 Male 206 lb 1/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Death 8/7/2006 4 Male 28 lb 1/29/2008 Physician Japan
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 60 Male 2/6/2008 Physician Italy
Primary
Concomitant
Acute Myocardial Infarction Other Serious Male 2/7/2008 Consumer United Kingdom
Primary
Concomitant
Pancytopenia Other Serious Male 2/7/2008 Consumer United Kingdom
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 4 Male 2/15/2008 Japan
Primary
Secondary
Concomitant
Myopericarditis Hospitalization 2/8/2008 60 Male 2/22/2008 Other Health Professional France
Primary
Concomitant

Drug Data