Etoposide combined with Leucovorin Calcium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Required Intervention 4/11/2006 Female 4/13/2006 United States
Primary
Secondary
Vomiting Hospitalization 4/11/2006 Female 214 lb 4/28/2006 United States
Primary
Secondary
Convulsion 5/22/2006 Female 8/8/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 7/18/2006 78 Female 8/25/2006 Pharmacist United States
Primary
Concomitant
Septic Shock Death 10/2/2006 Consumer France
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 10/2/2006 Consumer France
Primary
Secondary
Concomitant
Respiratory Failure Required Intervention 31 Female 10/23/2006 Japan
Primary
Secondary
Concomitant
Neutropenic Sepsis Death Female 10/23/2006 Physician Egypt
Primary
Secondary
Neutropenic Sepsis Death Female 10/23/2006 Physician Egypt
Primary
Secondary
Respiratory Failure Required Intervention 6/25/2004 31 Female 11/3/2006 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 6/25/2004 31 Female 11/3/2006 Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/2/2006 Female 51 lb 11/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 1/14/2007 Female 14 lb 1/17/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vith Nerve Paralysis Other Serious 10/22/2006 23 Male 172 lb 1/10/2007 Physician Finland
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/23/2006 Female 163 lb 4/4/2007 Physician Bahrain
Primary
Concomitant
Thrombocytopenia Other Serious 52 Male 4/17/2007 Other Health Professional United States
Primary
Secondary
Staphylococcal Infection Hospitalization 4/19/2007 Male 198 lb 5/8/2007 United States
Primary
Secondary
Renal Failure Acute Other Serious 7/18/2006 Female 5/17/2007 United States
Primary
Concomitant
Wound Abscess Hospitalization 6/6/2007 Male 45 lb 6/21/2007 United States
Primary
Secondary
Nephropathy Toxic Other Serious 4/1/2005 13 Male 7/2/2007 Other Health Professional United States
Primary
Secondary
Vith Nerve Paralysis Other Serious 10/22/2006 23 Male 172 lb 7/9/2007 United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/18/2007 Female 141 lb 7/20/2007 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/25/2007 Male 187 lb 7/30/2007 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 74 Male 8/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3 Male 35 lb 8/28/2007
Primary
Secondary
Urinary Tract Infection Other Serious 21 Female 9/5/2007 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Increased Other Serious 21 Female 8/16/2007 Physician United States
Primary
Secondary
Sepsis Neonatal Hospitalization Male 8/16/2007 Physician United States
Primary
Secondary
Myelodysplastic Syndrome Other Serious 3/1/2003 Male 10/17/2007
Primary
Secondary
Myelodysplastic Syndrome Other Serious 1/1/2007 74 Male 12/5/2007 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/11/2007 Male 289 lb 12/4/2007 United States
Primary
Secondary
Tachycardia Hospitalization 12/21/2007 Male 289 lb 1/7/2008 United States
Primary
Secondary
Sepsis Death 12/31/2007 65 Male 239 lb 1/10/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Death 12/31/2007 65 Male 239 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Refusal Of Treatment By Relative Other Serious 6 Male 1/22/2008 Physician Turkey
Primary
Concomitant
Laboratory Test Abnormal Hospitalization 4/26/2007 Male 139 lb 1/24/2008 United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 2/7/2008 Male 190 lb 2/12/2008 United States
Primary
Secondary
Treatment Noncompliance Hospitalization 2/19/2008 Male 187 lb 2/28/2008 United States
Primary
Secondary
Haemoglobin Decreased Death 6 Male 3/10/2008
Primary
Secondary
Concomitant
Refusal Of Treatment By Relative Disability 6 Male 5/19/2008 Physician Turkey
Primary
Concomitant
Muscle Disorder Disability 5/13/2006 Male 6/23/2008 Consumer Germany
Primary
Secondary
Concomitant
Malabsorption 7/28/2008 Male 125 lb 7/28/2008 United States
Primary
Secondary
Transient Ischaemic Attack Hospitalization 7/22/2008 9 Male 76 lb 8/8/2008 Physician United States
Primary
Secondary
Concomitant
Intra-abdominal Haemorrhage Death Unknown 8/8/2008 United Kingdom
Primary
Secondary
Concomitant
Wound Infection Bacterial Hospitalization 5/27/2007 Female 141 lb 6/20/2007 United States
Primary
Secondary
Gastric Cancer Other Serious 77 Female 8/29/2008 Physician Austria
Primary
Secondary
Sinusitis Other Serious 4/1/2002 Male 9/15/2008 Consumer France
Primary
Secondary
Concomitant
Urine Leukocyte Esterase Positive Hospitalization 10/5/2008 Male 209 lb 10/9/2008 United States
Primary
Secondary
Weight Increased Hospitalization 48 Female 11/3/2008 Netherlands
Primary
Secondary
Concomitant
Sinusitis Other Serious 4/1/2002 Male 11/24/2008 Consumer France
Primary
Secondary
Concomitant
Death Death 67 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 66 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Sinusitis Other Serious 4/1/2002 12/17/2008 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 27 Female 12/12/2008 Germany
Primary
Secondary
Concomitant
Vomiting Life Threatening 11/24/2008 55 Male 123 lb 12/30/2008 Physician Ecuador
Primary
Concomitant
Urine Leukocyte Esterase Positive Hospitalization 11/23/2008 Male 209 lb 1/8/2009 United States
Primary
Secondary
Pharyngeal Oedema Hospitalization 12/27/2008 Male 183 lb 12/30/2008 United States
Primary
Secondary
Pyrexia Other Serious 10 Male 2/10/2009
Primary
Secondary
Concomitant
Sepsis Hospitalization 11/15/2008 Male 192 lb 2/9/2009 United States
Primary
Secondary
Weight Decreased Hospitalization 10/6/2008 Male 192 lb 2/11/2009 United States
Primary
Secondary
Respiratory Failure Other Serious 10/1/2007 Female 3/24/2009 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 4/14/2009 Consumer United Kingdom
Primary
Secondary
Febrile Neutropenia Other Serious 4/27/2009 Consumer United Kingdom
Primary
Secondary
Upper Respiratory Tract Infection Hospitalization 9/3/2008 1 Female 15 lb 4/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/2/2009 Male 157 lb 5/19/2009 United States
Primary
Secondary
Thrombocytopenia Other Serious 6/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Salivary Gland Mass Other Serious 1/1/2008 38 Female 6/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/12/2009 Male 163 lb 6/23/2009 United States
Primary
Secondary
Somnolence Other Serious 1/11/2010 United States
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 11/12/2009 Female 15 lb 1/12/2010 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Toxicity Other Serious 4/29/2010 United States
Primary
Secondary
Skin Toxicity Death 4/30/2010 Physician United Kingdom
Primary
Secondary
Syncope Other Serious 10/6/2007 50 Male 194 lb 6/30/2010 Lawyer United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2009 59 Female 132 lb 8/23/2010 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 9/20/2007 50 Male 194 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Test Positive Life Threatening 11/16/2010 14 Female 130 lb 11/24/2010 Physician United States
Primary
Secondary
Concomitant
Headache Other Serious 9/1/2007 50 Male 194 lb 1/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Burning Sensation Hospitalization Male 101 lb 3/3/2011 Other Health Professional Canada
Primary
Concomitant
Anxiety Death 3/8/2011 15 Female 144 lb 3/23/2011 Physician United States
Primary
Secondary
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 4/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Life Threatening 11/16/2010 14 Female 130 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Infection Hospitalization 11/2/2010 18 Male 124 lb 5/13/2011 Physician United States
Primary
Secondary
Pleural Effusion Death 3/8/2011 15 Female 144 lb 5/24/2011 Physician United States
Primary
Secondary
Hypernatraemia Life Threatening 11/16/2010 14 Female 130 lb 6/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 8/25/2009 13 Male 102 lb 6/7/2011 United States
Primary
Secondary
Neoplasm Malignant Death 5 6/25/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 5 6/25/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Acute Graft Versus Host Disease Death 3 6/25/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Maternal Exposure During Pregnancy Other Serious Female 7/14/2011 Other Health Professional India
Primary
Secondary
Toxicity To Various Agents Death 7/14/2011 Other Health Professional France
Primary
Secondary
Pregnancy Other Serious Female 7/14/2011 Physician India
Primary
Secondary
Maternal Exposure During Pregnancy Other Serious Female 7/14/2011 Physician India
Primary
Secondary
Toxicity To Various Agents Death 7/14/2011 Other Health Professional France
Primary
Secondary
Maternal Exposure During Pregnancy Other Serious Female 7/14/2011 Physician India
Primary
Secondary
Maternal Exposure During Pregnancy Other Serious Female 7/14/2011 Physician India
Primary
Secondary
Toxicity To Various Agents Death 7/14/2011 Other Health Professional France
Primary
Secondary
Maternal Exposure During Pregnancy Other Serious Female 7/14/2011 Physician India
Primary
Secondary
Pregnancy Other Serious Female 7/14/2011 Other Health Professional India
Primary
Secondary
Maternal Exposure During Pregnancy Other Serious Female 7/14/2011 Other Health Professional India
Primary
Secondary
Maternal Exposure During Pregnancy Other Serious Female 7/14/2011 Other Health Professional India
Primary
Secondary
B-cell Lymphoma Other Serious 8/4/2011 48 Male 9/22/2011 Consumer United Kingdom
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 3/9/2011 43 Male 202 lb 9/29/2011 United States
Primary
Secondary
Acute Myeloid Leukaemia Hospitalization 3/9/2011 43 Male 202 lb 9/29/2011 United States
Primary
Secondary
Cardiac Failure Other Serious 10/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Death Death 10/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Leukopenia Hospitalization 9/28/2011 10 Female 109 lb 11/16/2011 Other Health Professional France
Primary
Secondary
Concomitant
Infection Hospitalization 2/15/2005 17 11/21/2011 United States
Primary
Secondary
Convulsion Life Threatening 6/14/2005 20 11/21/2011 United States
Primary
Secondary
Leukopenia Hospitalization 9/28/2011 10 Female 109 lb 11/23/2011 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/10/2001 11 Male 11/29/2011 Physician United States
Primary
Secondary
Off Label Use Hospitalization 44 Male 11/30/2011 Other Health Professional
Primary
Secondary
Concomitant
Death Death 12/16/2011 Physician France
Primary
Secondary
Blood Creatinine Increased Other Serious 12/16/2011 Physician France
Primary
Secondary
Adverse Event Other Serious 12/19/2011 Physician France
Primary
Secondary
Cardiac Disorder Other Serious 12/19/2011 Physician France
Primary
Secondary
Lung Neoplasm Malignant Other Serious 12/19/2011 Physician France
Primary
Secondary
Pancreatitis Hospitalization 12/15/2011 9 Male 69 lb 12/16/2011 United States
Primary
Secondary
Leukopenia Other Serious 2/26/2007 68 Male 173 lb 12/20/2011 Consumer United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 8/13/2009 48 Female 133 lb 12/20/2011 Physician United States
Primary
Secondary
Concomitant
Neutropenic Infection Other Serious 8/22/2010 25 Male 238 lb 12/20/2011 Physician United States
Primary
Secondary
Blood Magnesium Abnormal Hospitalization 8/18/2010 65 Male 238 lb 12/20/2011 Physician United States
Primary
Secondary
Leukopenia Hospitalization 2/7/2009 69 Male 223 lb 12/21/2011 Other Health Professional United States
Primary
Secondary
Lung Neoplasm Malignant Other Serious 12/21/2011 Physician France
Primary
Secondary
Pyrexia Hospitalization 10/1/2001 11 Male 12/22/2011 Consumer United States
Primary
Secondary
Infection Life Threatening 12/8/2001 12 Male 12/23/2011 Physician United States
Primary
Secondary
Lymphopenia Hospitalization 8/18/2010 65 Male 238 lb 12/27/2011 Physician United States
Primary
Secondary
Left Ventricular Dysfunction Other Serious 2/26/2007 68 Male 173 lb 12/27/2011 Consumer United States
Primary
Secondary
Concomitant
Neurotoxicity Death 12/27/2011 Physician France
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 2/26/2007 68 Male 173 lb 12/29/2011 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 7/15/2011 52 Female 185 lb 2/3/2012 Physician Netherlands
Primary
Secondary
Death Death 2/8/2012 Other Health Professional France
Primary
Secondary
Lung Neoplasm Malignant Other Serious 2/8/2012 Other Health Professional France
Primary
Secondary
Sepsis Death 2/9/2012 Other Health Professional France
Primary
Secondary
Sepsis Death 2/9/2012 Other Health Professional France
Primary
Secondary
Sepsis Death 2/9/2012 Other Health Professional France
Primary
Secondary
Pulmonary Embolism Other Serious 7/15/2011 52 Female 185 lb 2/16/2012 Consumer Netherlands
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 11/21/2004 16 2/16/2012 United States
Primary
Secondary
Infection Hospitalization 10/10/2001 11 Male 2/17/2012 Physician United States
Primary
Secondary
Leukoencephalopathy Hospitalization 9/28/2011 10 Female 112 lb 2/22/2012 Physician France
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 1/4/2004 21 Female 2/28/2012 Physician United States
Primary
Secondary
Pulmonary Embolism Hospitalization 7/15/2011 52 Female 185 lb 3/7/2012 Consumer Netherlands
Primary
Secondary

Drug Data