Etoposide combined with Ifosfamide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Neurotoxicity Death 36 Female 1/4/2006 Consumer Japan
Primary
Secondary
Tongue Disorder Other Serious 12/5/2005 Male 216 lb 12/27/2005 United States
Primary
Secondary
Neurotoxicity Death 36 Female 1/5/2006 Physician Turkey
Primary
Secondary
Concomitant
Leukoencephalopathy Death 36 Female 1/26/2006 Consumer Japan
Primary
Secondary
Swelling Death 36 Female 1/31/2006 Physician Turkey
Primary
Secondary
Swelling Death 36 Female 2/13/2006 Physician Turkey
Primary
Secondary
Therapy Non-responder Death 36 Female 2/14/2006 Physician Turkey
Primary
Secondary
Staphylococcal Infection Hospitalization 11/23/2005 Male 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 6/4/2005 14 Male 3/6/2006 Physician Japan
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 36 Male 161 lb 3/16/2006 Japan
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 53 Female 3/21/2006 Other Health Professional Turkey
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 55 Female 3/21/2006 Other Health Professional Turkey
Primary
Secondary
Urinary Tract Infection Other Serious 3/6/2006 Female 111 lb 3/15/2006 United States
Primary
Secondary
T-cell Lymphoma Hospitalization 36 Female 3/17/2006 Physician Turkey
Primary
Secondary
Pyrexia Hospitalization 47 Male 3/23/2006 Consumer Germany
Primary
Concomitant
Constipation Other Serious Male 3/17/2006 Physician Japan
Primary
Concomitant
Trismus Hospitalization 8/2/2005 14 Male 3/20/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Acute Myocardial Infarction Life Threatening 3/8/2006 54 Male 3/22/2006 Physician Germany
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 7/22/2005 63 Male 108 lb 3/22/2006 Physician France
Primary
Secondary
Concomitant
Stupor Death 36 Female 3/24/2006 Turkey
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/3/2004 49 Female 3/27/2006 Physician Japan
Primary
Secondary
Concomitant
Performance Status Decreased Other Serious 3/13/2006 Male 216 lb 3/29/2006 United States
Primary
Secondary
Pancytopenia Life Threatening 2/27/2006 20 Male 139 lb 4/4/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Coronary Artery Disease Life Threatening 3/8/2006 54 Male 210 lb 3/30/2006 Physician Germany
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 3/7/2006 55 Male 4/6/2006 Consumer United States
Primary
Secondary
Osteonecrosis Other Serious 11/9/2005 65 Female 95 lb 4/7/2006 Physician Germany
Primary
Concomitant
Thinking Abnormal Other Serious 4/8/2006 12 Male 83 lb 4/10/2006 Pharmacist United States
Primary
Concomitant
Pancytopenia Life Threatening 2/27/2006 20 Male 139 lb 4/13/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Required Intervention 4/11/2006 Female 4/13/2006 United States
Primary
Secondary
Vomiting Hospitalization 4/11/2006 Female 214 lb 4/28/2006 United States
Primary
Secondary
Death Death 38 Male 5/25/2006 Korea, Democratic People's Republic Of
Primary
Secondary
Pneumonia Streptococcal Other Serious 7/1/2004 52 Male 6/14/2006 Other Health Professional Korea, Republic Of
Primary
Secondary
Thrombocytopenia Other Serious 16 Male 6/6/2006 Physician United States
Primary
Concomitant
Respiratory Disorder Death 2/26/2004 6 Male 6/16/2006 Consumer Japan
Primary
Secondary
Pneumonia Death 6/15/2006 Austria
Primary
Secondary
Stomatitis Other Serious 5/1/2004 54 Female 154 lb 6/22/2006 Physician Germany
Primary
Concomitant
Rash Hospitalization Male 212 lb 6/30/2006 Physician Germany
Primary
Concomitant
Tongue Disorder Hospitalization 6/1/2006 Male 212 lb 7/18/2006 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/28/2006 27 Male 7/29/2006 Physician United States
Primary
Secondary
Concomitant
Constipation 10/9/2004 76 Male 7/27/2006 Physician Japan
Primary
Concomitant
Adverse Event Death 7/27/2006 Physician Germany
Primary
Secondary
Septic Shock Death 7/28/2006 Physician Germany
Primary
Secondary
White Blood Cell Count Abnormal Other Serious 33 Male 8/11/2006 Physician Japan
Primary
Secondary
Sudden Death Death 8/6/2006 43 Male 8/23/2006 Physician Sweden
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 6/28/2006 27 Male 8/26/2006 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 9/21/2005 70 Male 6/6/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 64 Male 9/1/2006 Japan
Primary
Secondary
Septic Embolus Other Serious 33 Male 9/15/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 8/16/2006 Female 108 lb 9/8/2006 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 65 Male 9/15/2006 Japan
Primary
Secondary
Death Death Unknown 9/19/2006 France
Primary
Secondary
Drug Toxicity Death Unknown 9/20/2006 France
Primary
Secondary
Drug Toxicity Death Unknown 9/20/2006 Consumer France
Primary
Secondary
Drug Toxicity Death Unknown 9/20/2006 France
Primary
Secondary
Chondrosarcoma Other Serious 37 Male 9/27/2006 Other Health Professional Greece
Primary
Concomitant
Infection Death 9/21/2006 Physician France
Primary
Secondary
Pulmonary Fibrosis Hospitalization 17 Male 10/2/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Septic Shock Death 10/2/2006 Consumer France
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 10/2/2006 Consumer France
Primary
Secondary
Concomitant
Lung Infection Pseudomonal Other Serious 50 Female 9/29/2006 Canada
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 8/16/2006 Female 108 lb 9/27/2006 United States
Primary
Secondary
Stem Cell Transplant Death Unknown 9/29/2006 France
Primary
Secondary
Concomitant
Malignant Transformation Other Serious 37 Male 9/26/2006 Physician Greece
Primary
Secondary
Neurotoxicity Other Serious Unknown 9/29/2006 France
Primary
Secondary
Concomitant
Teratoma Hospitalization 37 Male 10/4/2006 Greece
Primary
Secondary
Stem Cell Transplant Other Serious 33 Male 10/12/2006 United States
Primary
Secondary
Thrombocytopenia Other Serious 16 Female 10/18/2006 Physician France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/14/2004 50 Female 10/24/2006 Other Health Professional Australia
Primary
Secondary
Pollakiuria Hospitalization 4/17/2005 58 Female 10/26/2006 Other Health Professional Australia
Primary
Secondary
Respiratory Depression Other Serious 34 Male 10/27/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Pain Hospitalization 5/1/2006 44 Female 10/19/2006 Physician United States
Primary
Secondary
Sinus Tachycardia Hospitalization 8/31/2006 47 112 lb 10/23/2006 Physician Germany
Primary
Secondary
Somnolence Other Serious 34 Male 10/25/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Pulmonary Fibrosis Hospitalization 17 Male 11/3/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pollakiuria Hospitalization 4/17/2005 58 Female 11/7/2006 Consumer Australia
Primary
Secondary
Thrombocytopenia Other Serious 16 Female 11/27/2006
Primary
Secondary
Concomitant
Myelodysplastic Syndrome Other Serious 53 Female 11/22/2006 Physician Australia
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 11/30/2006 Male 254 lb 12/6/2006 United States
Primary
Secondary
Tremor Hospitalization 11/20/2006 Female 216 lb 12/6/2006 United States
Primary
Secondary
Pyrexia Hospitalization 5/14/2004 50 Female 12/15/2006 Other Health Professional Australia
Primary
Secondary
Vomiting Hospitalization 8 Male 12/12/2006 Physician Sweden
Primary
Concomitant
Renal Failure Acute Hospitalization 8/4/2006 Male 1/12/2007 Australia
Primary
Secondary
Toxic Epidermal Necrolysis Death 2/13/2007 Germany
Primary
Secondary
Concomitant
Arrhythmia Death Unknown 2/13/2007 Germany
Primary
Secondary
Concomitant
Paranoia Hospitalization 8/24/2006 55 Male 2/27/2007 France
Primary
Secondary
Azoospermia Other Serious 32 Male 3/8/2007 Other Health Professional Japan
Primary
Secondary
Blood Luteinising Hormone Increased Other Serious 32 Male 3/6/2007 Japan
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 16 Female 3/14/2007 Other Health Professional France
Primary
Secondary
Shock Hospitalization 27 Male 3/15/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Visual Acuity Reduced Life Threatening 16 Female 110 lb 3/15/2007
Primary
Secondary
Stomatitis Life Threatening 1/29/2007 68 Male 159 lb 3/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Radiation Pneumonitis Hospitalization 3/8/2007 Female 181 lb 3/9/2007 United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 16 Female 110 lb 3/21/2007 Other Health Professional France
Primary
Secondary
Shock Other Serious 5/1/2005 27 Male 3/22/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Blood Luteinising Hormone Increased Other Serious 32 Male 3/15/2007 Japan
Primary
Secondary
Stomatitis Life Threatening 1/29/2007 68 Male 3/22/2007 United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/11/2006 Female 3/28/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased 1/1/2005 Female 3/28/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 8/18/2005 64 Male 3/22/2007 Physician Switzerland
Primary
Secondary
Stomatitis Other Serious 3/30/2007 Other Health Professional Germany
Primary
Secondary
Staphylococcal Sepsis Other Serious 31 Male 4/4/2007 Other Health Professional United States
Primary
Secondary
Peritonitis Hospitalization 11/27/2006 64 Male 3/28/2007 Physician Japan
Primary
Concomitant
Vomiting Other Serious 4/5/2007 Other Health Professional France
Primary
Secondary
Concomitant
Drug Toxicity Required Intervention 2/9/2007 52 Female 3/5/2007 Pharmacist United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 26 Male 4/13/2007 Other Health Professional Japan
Primary
Secondary
Respiratory Failure Hospitalization 6 Female 4/13/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Shock Hospitalization 27 Male 4/4/2007 Australia
Primary
Secondary
Concomitant
Radiation Pneumonitis Hospitalization 3/8/2007 Female 181 lb 4/11/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Tachycardia Other Serious 2/16/2005 17 Male 4/18/2007 Other Health Professional Malaysia
Primary
Secondary
Lymphoma Other Serious 62 Female 4/18/2007 Other Health Professional Japan
Primary
Secondary
Lymphoma Other Serious 11/1/1998 62 Female 4/20/2007 Other Health Professional Japan
Primary
Secondary
Staphylococcal Infection Other Serious 45 Male 143 lb 4/13/2007 Physician Japan
Primary
Concomitant
Mucosal Inflammation Other Serious 51 Male 4/24/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious Unknown 4/16/2007 Germany
Primary
Secondary
Pneumonitis Death 3 Male 4/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Stridor Death 6 Female 4/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 61 Female 4/18/2007 Physician Netherlands
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious 4/27/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3 Male 4/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Urine Output Decreased Other Serious 27 Male 4/24/2007 Physician Australia
Primary
Secondary
Concomitant
Interstitial Lung Disease Death 3 Male 5/9/2007 United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 4/19/2007 Male 198 lb 5/8/2007 United States
Primary
Secondary
Sputum Culture Positive Death 6 Female 5/1/2007 United Kingdom
Primary
Secondary
Weaning Failure Death 2 Male 5/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Stridor Death 6 Female 5/8/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Weaning Failure Death 3 Male 5/4/2007 United Kingdom
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 36 Female 5/25/2007 Physician Turkey
Primary
Secondary
Respiratory Failure Other Serious 3 Male 6/1/2007 United Kingdom
Primary
Secondary
Concomitant
Leukoencephalopathy Life Threatening 2/21/2007 Male 6/1/2007 Physician Czech Republic
Primary
Secondary
Respiratory Failure Hospitalization 3 Male 6/4/2007 United Kingdom
Primary
Secondary
Respiratory Failure Death 3 Male 5/25/2007 United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 6/1/2007 Physician Germany
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 6/1/2007 Physician Germany
Primary
Secondary
Acute Myeloid Leukaemia Death 15 Male 6/11/2007 Consumer Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3 Male 6/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Xerosis Hospitalization 11 Male 6/13/2007 Physician United States
Primary
Concomitant
Malignant Neoplasm Progression Death 1/1/2007 Male 6/18/2007 Pharmacist United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 3 Male 6/19/2007 United Kingdom
Primary
Secondary
Concomitant
Tumour Necrosis Other Serious 17 Male 6/16/2007 United States
Primary
Secondary
Respiratory Failure Hospitalization 3 Male 6/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Skin Reaction Death 3 Male 6/20/2007 United Kingdom
Primary
Secondary
Nephrogenic Fibrosing Dermopathy Death 15 Male 77 lb 6/27/2007 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 3 Male 6/29/2007 United Kingdom
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 1/1/2007 Male 7/2/2007 Pharmacist United Kingdom
Primary
Concomitant
Streptococcal Infection Death 6 Female 7/3/2007 United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious Female 7/3/2007
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 4/1/2005 13 Male 7/2/2007 Other Health Professional United States
Primary
Secondary
Weaning Failure Hospitalization 3 Male 7/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Failure Hospitalization 3 Male 7/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Febrile Neutropenia Hospitalization 7/4/2007 Male 168 lb 7/13/2007 Consumer Australia
Primary
Secondary
Concomitant

Drug Data