Ethambutol combined with Isoniazid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myopathy Disability 6/29/2005 Female 2/17/2006 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/21/2005 57 Female 2/28/2006 Physician United States
Primary
Secondary
Concomitant
Drug Level Increased Other Serious 40 Female 3/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Hospitalization 2/21/2006 49 Female 3/21/2006
Primary
Secondary
International Normalised Ratio Increased Life Threatening 2/1/2006 27 Female 106 lb 3/14/2006 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2005 57 Female 4/11/2006 Physician United States
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 2/12/2006 50 Male 4/14/2006 Other Health Professional France
Primary
Secondary
Concomitant
Rash Other Serious 80 Male 4/21/2006 Physician Japan
Primary
Concomitant
Hepatitis B Surface Antigen Positive Other Serious 3/30/2006 55 Male 148 lb 5/5/2006 Physician Philippines
Primary
Interacting
Drug Interaction Other Serious 3/30/2006 55 Male 148 lb 5/5/2006 Physician Philippines
Primary
Interacting
Weight Decreased Hospitalization 2/25/2004 Female 82 lb 5/8/2006 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 4/6/2006 53 Male 102 lb 5/17/2006 United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 39 Male 5/11/2006
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 4/6/2006 53 Male 102 lb 5/18/2006 United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 4/15/2006 24 Male 5/24/2006 Other Health Professional France
Primary
Secondary
Skin Hyperpigmentation Hospitalization 2/25/1998 31 Female 5/19/2006 Other Health Professional Tunisia
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening Unknown 6/12/2006 Physician Benin
Primary
Secondary
Concomitant
Splenomegaly Hospitalization 2/12/2006 Male 6/21/2006 Other Health Professional France
Primary
Secondary
Concomitant
Cardiac Arrest Death 6/13/2006 51 Female 6/26/2006 Germany
Primary
Concomitant
Vomiting Other Serious 7/31/2007 Male 115 lb 9/7/2007 Other Health Professional United States
Primary
Secondary
Pulmonary Tuberculosis Hospitalization 6/9/2007 27 Female 60 lb 9/18/2007 United States
Primary
Secondary
Concomitant
Tuberculosis Other Serious 0 9/21/2007 Netherlands
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/6/2007 51 Male 121 lb 9/25/2007 Physician Thailand
Primary
Concomitant
Tuberculosis Other Serious Male 1/5/2009 Consumer Japan
Primary
Secondary
Concomitant
Hypertensive Encephalopathy Life Threatening 60 Female 1/5/2009 Consumer Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 3/1/2005 58 Male 1/5/2009 Consumer Japan
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 11/19/2008 28 Male 1/5/2009 Physician United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 1/1/2005 80 Female 77 lb 1/5/2009
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 1/1/2005 80 Female 77 lb 1/5/2009
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 11/24/2006 60 Male 1/6/2009
Primary
Secondary
Concomitant
Renal Failure Death 51 Male 12/30/2008 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/10/2008 1 Male 2/11/2009 Physician France
Primary
Concomitant
Jaundice Hospitalization 12/14/2008 3/10/2009 Other Health Professional France
Primary
Secondary
Concomitant
Nightmare Other Serious 38 Female 137 lb 5/1/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Death 5/23/2009 43 Male 119 lb 6/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Splenic Rupture Other Serious 36 Male 7/9/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Death 5/23/2009 43 Male 119 lb 7/9/2009 United States
Primary
Secondary
Concomitant
Weight Decreased Death 6/20/2009 40 Male 98 lb 7/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Paradoxical Drug Reaction Other Serious 19 Female 7/16/2009 Korea, Republic Of
Primary
Secondary
Nervous System Disorder Other Serious 27 Male 6/12/2009 Physician Canada
Primary
Secondary
Concomitant
Meningitis Tuberculous Death 40 Male 98 lb 7/27/2009 United States
Primary
Secondary
Concomitant
Cachexia Hospitalization 10/6/2008 Male 122 lb 7/31/2009 China
Primary
Concomitant
Pulmonary Tuberculosis Death 6/29/2009 46 Male 112 lb 7/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 7/27/2009 40 Female 108 lb 8/11/2009 Physician United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 7/27/2009 Female 108 lb 8/14/2009 Physician United States
Primary
Secondary
Concomitant
Death Death 6/29/2009 46 Male 112 lb 8/14/2009 United States
Primary
Secondary
Concomitant
Meningitis Tuberculous Death 40 Male 98 lb 8/14/2009 United States
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Death 54 Male 8/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Meningitis Tuberculous Other Serious 77 Female 8/28/2009
Primary
Concomitant
Neutropenia Other Serious 7/27/2009 Female 108 lb 9/4/2009 Physician United States
Primary
Secondary
Concomitant
Hepatotoxicity Life Threatening 8/28/2009 29 Female 108 lb 9/8/2009 Consumer United States
Primary
Secondary
Concomitant
Coma Hepatic Life Threatening 8/31/2009 29 Female 108 lb 9/9/2009 Consumer United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 8/28/2009 29 Female 108 lb 9/14/2009 Consumer United States
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 6/8/2009 Female 71 lb 9/16/2009 Physician Uganda
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 20 Male 9/17/2009
Primary
Secondary
Concomitant
Vomiting Congenital Anomaly 4/9/2009 23 Female 99 lb 9/22/2009 Physician South Africa
Primary
Secondary
Concomitant
Hepatic Failure Life Threatening 9/4/2009 Female 165 lb 9/25/2009 Physician Romania
Primary
Concomitant
Hepatic Failure Life Threatening 9/4/2009 Female 165 lb 9/29/2009 Physician Romania
Primary
Concomitant
Neutropenia Other Serious 7/27/2009 Female 108 lb 11/27/2009 Physician United States
Primary
Secondary
Concomitant
Anaphylactic Reaction Other Serious 1/1/2009 83 Male 2/19/2010 Other Health Professional France
Primary
Secondary
Death Death 12/5/2009 70 Male 106 lb 2/26/2010 Consumer United States
Primary
Secondary
Concomitant
Tuberculosis Other Serious 7/1/2003 63 Male 5/6/2010 Other Health Professional Saudi Arabia
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/1/2008 56 Male 5/6/2010 Consumer United Kingdom
Primary
Secondary
Paradoxical Drug Reaction Other Serious 1/1/2009 38 Male 5/6/2010 Other Health Professional Korea, Democratic People's Republic Of
Primary
Secondary
Bone Tuberculosis Hospitalization 63 Male 5/11/2010 Other Health Professional Saudi Arabia
Primary
Secondary
Swelling Face Hospitalization 56 Male 5/11/2010 Other Health Professional China
Primary
Concomitant
Hepatitis Death 84 Female 110 lb 5/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 28 Female 5/17/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 11/1/2008 73 Female 5/24/2010 Physician Japan
Primary
Secondary
Pachymeningitis Other Serious 23 Male 7/22/2010 Physician China
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 73 Male 9/9/2010 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 73 Male 11/15/2010 Physician Japan
Primary
Concomitant
Nausea 7/23/2009 20 Female 3/1/2011 Physician United States
Primary
Secondary
Ventricular Extrasystoles Hospitalization 71 Male 185 lb 5/17/2011 Pharmacist Germany
Primary
Concomitant
Interacting
Paradoxical Drug Reaction Hospitalization 23 Male 5/13/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Fibrin Degradation Products Increased Other Serious 38 Male 6/8/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Blood Immunoglobulin E Increased Other Serious 43 Male 6/8/2011 Other Health Professional Tunisia
Primary
Concomitant
Thrombocytopenia Other Serious 55 Male 6/8/2011 Other Health Professional Tunisia
Primary
Concomitant
Subdural Haemorrhage Hospitalization 68 Female 6/8/2011 Other Health Professional Korea, Democratic People's Republic Of
Primary
Concomitant
Confusional State Hospitalization 50 Female 6/8/2011 Other Health Professional Italy
Primary
Concomitant
Paradoxical Drug Reaction Other Serious 5 Male 6/20/2011 Other Health Professional India
Primary
Secondary
Concomitant
C-reactive Protein Increased Hospitalization 44 Male 6/13/2011 Other Health Professional Spain
Primary
Concomitant
Eosinophilia Hospitalization 16 Male 6/24/2011 Other Health Professional Spain
Primary
Secondary
Fear Other Serious 6/21/2002 33 Female 185 lb 6/29/2011 Consumer United States
Primary
Concomitant
Pneumonitis Hospitalization 86 Male 106 lb 8/9/2011 Other Health Professional Japan
Primary
Concomitant
Hepatitis Hospitalization 7/28/2011 36 Female 8/22/2011 Physician Uganda
Primary
Secondary
Concomitant
Dizziness Other Serious 44 Male 9/6/2011 Physician Romania
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 1/23/2004 53 Male 9/5/2011 Physician Switzerland
Primary
Concomitant
Hypokalaemia Hospitalization 7/28/2011 36 Female 9/7/2011 Consumer Italy
Primary
Secondary
Concomitant
Acute Hepatic Failure Hospitalization 7 Male 11/9/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Porphyria Non-acute Hospitalization 59 Male 3/28/2012 Other Health Professional Hong Kong
Primary
Secondary
Thrombocytopenic Purpura Hospitalization 32 Female 6/26/2012 Physician India
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 5/3/2012 67 Female 93 lb 7/12/2012 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 5/3/2012 67 Female 93 lb 7/20/2012 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 5/3/2012 67 Female 93 lb 7/26/2012 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 5/3/2012 67 Female 93 lb 7/31/2012 Physician Japan
Primary
Secondary
Concomitant
Vomiting Death 8/2010 34 Male 115 lb 11/19/2012 Physician Ke
Primary
Secondary
Concomitant
Nausea Other Serious 2/10/2011 38 Male 99 lb 10/17/2012 Physician Tz
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 28 Female 12/3/2012 Physician Es
Primary
Concomitant
Pain Hospitalization 6/2011 Male 99 lb 11/20/2012 Pharmacist Jp
Primary
Concomitant
Interacting
Polyneuropathy Other Serious 24 Female 10/8/2012 Physician Es
Primary
Concomitant
Interacting
Rash Other Serious 5/2010 56 Female 9/4/2012 Country Not Specified
Primary
Secondary
Concomitant
Pyrexia Other Serious 10/18/2012 Other Health Professional Il
Primary
Secondary
Concomitant
Drug Ineffective 78 Female 10/19/2012 Other Health Professional Jp
Primary
Secondary
Deep Vein Thrombosis Hospitalization 3/10/2011 32 Male 8/29/2012 Physician Br
Primary
Secondary
White Blood Cell Count Decreased Other Serious 6/25/2012 34 Male 12/10/2012 Other Health Professional Gb
Primary
Concomitant
Interacting
Tuberculoma Of Central Nervous System Hospitalization 31 Female 8/28/2012 Other Health Professional Sa
Primary
Secondary
Concomitant
Pneumonia Life Threatening 8/27/2012 31 Male 11/16/2012 Physician Au
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2010 46 Male 9/26/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Drug Reaction With Eosinophilia And Systemic Symptoms Hospitalization 19 Male 9/27/2012 Other Health Professional Es
Primary
Secondary
Pyrexia Other Serious 1/2012 40 Female 10/2/2012 Physician Br
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/21/2012 24 Male 124 lb 11/16/2012 Physician Th
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/25/2012 34 Male 12/21/2012 Physician Gb
Primary
Concomitant
Interacting
Toxic Epidermal Necrolysis Other Serious 10/4/2012 Physician Za
Primary
Secondary
Simplex Virus Test Positive Other Serious 19 Male 10/4/2012 Other Health Professional Es
Primary
Secondary
Meningitis Other Serious 2 Male 31 lb 10/11/2012 Other Health Professional In
Primary
Secondary
Concomitant
Visual Impairment Other Serious 5/2006 4 Male 10/11/2012 In
Primary
Secondary
White Blood Cell Count Increased Hospitalization 26 Female 12/13/2012 Other Health Professional Kr
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 20 Male 10/18/2012 Other Health Professional Au
Primary
Concomitant
Liver Injury Hospitalization 58 Male 11/26/2012 Other Health Professional Jp
Primary
Concomitant
Skin Fissures Hospitalization 39 Male 10/19/2012 Other Health Professional Za
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 58 Male 10/26/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Somnolence Hospitalization 63 Male 10/23/2012 Other Health Professional Kr
Primary
Concomitant
Tuberculoma Of Central Nervous System Other Serious Male 11/5/2012 Other Health Professional In
Primary
Secondary
Rash Papular Hospitalization 19 Male 11/3/2012 Other Health Professional Es
Primary
Secondary
Visual Impairment Other Serious Male 11/3/2012 Other Health Professional In
Primary
Secondary
Respiratory Rate Increased Hospitalization 18 Male 11/9/2012 Other Health Professional In
Primary
Secondary
Concomitant
Urticaria Hospitalization 19 Male 11/12/2012 Other Health Professional Es
Primary
Secondary
Tuberculoma Of Central Nervous System Other Serious Male 11/20/2012 Other Health Professional In
Primary
Secondary
Tuberculoma Of Central Nervous System Other Serious 5/2006 3 Male 11/12/2012 Other Health Professional In
Primary
Secondary
Immune Reconstitution Inflammatory Syndrome Associated Tuberculosis Other Serious 44 Male 11/30/2012 Other Health Professional Es
Primary
Secondary
Concomitant
Tuberculoma Of Central Nervous System Other Serious 2 Male 31 lb 11/14/2012 Other Health Professional In
Primary
Secondary
Concomitant
Tuberculoma Of Central Nervous System Other Serious 2006 Male 11/14/2012 Other Health Professional In
Primary
Secondary
Concomitant
Respiratory Failure Death 52 Male 11/14/2012 Other Health Professional In
Primary
Secondary
Pericardial Effusion Other Serious 5/2012 90 Male 11/14/2012 Other Health Professional Jp
Primary
Concomitant
Swelling Face Other Serious Female 11/1/2012 Other Health Professional In
Primary
Secondary
Spleen Palpable Hospitalization 18 Male 11/9/2012 Other Health Professional In
Primary
Secondary
Tuberculoma Of Central Nervous System Other Serious 4 Male 11/16/2012 Other Health Professional In
Primary
Secondary
Tuberculoma Of Central Nervous System Other Serious 2 Male 11/16/2012 Other Health Professional In
Primary
Secondary
Vomiting Hospitalization 2011 Female 77 lb 11/22/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Somnolence Required Intervention 63 Male 11/5/2012 Kr
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1997 Male 11/21/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Vomiting Other Serious 7/2010 56 Female 11/21/2012 Other Health Professional Jp
Primary
Secondary
Concomitant
Skin Hyperpigmentation Hospitalization 39 Male 11/20/2012 Other Health Professional Za
Primary
Secondary
Concomitant
Scrotal Disorder Other Serious 15 Male 11/15/2012 Other Health Professional In
Primary
Concomitant
Histiocytosis Haematophagic Death 63 Male 12/19/2012 Physician Es
Primary
Secondary
Concomitant
Pneumonia Other Serious 63 Male 11/29/2012 Other Health Professional Fr
Primary
Secondary
Concomitant
Interacting
Respiratory Alkalosis Hospitalization 12/3/2012 Other Health Professional In
Primary
Secondary
Rash Maculo-papular Other Serious 31 Male 12/3/2012 Physician Jp
Primary
Secondary
Peritoneal Tuberculosis Hospitalization 89 Female 77 lb 12/4/2012 Other Health Professional Jp
Primary
Secondary

Drug Data