Etanercept combined with Leflunomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Temporomandibular Joint Syndrome Hospitalization Male 2/9/2006 Germany
Primary
Concomitant
Cutaneous Lupus Erythematosus Other Serious 64 Female 3/6/2006 Physician United States
Primary
Secondary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 2/24/2006 France
Primary
Secondary
Shock Death 60 Female 10/27/2006 Physician France
Primary
Secondary
Concomitant
Staphylococcal Sepsis Hospitalization 10/8/2006 62 Female 154 lb 12/11/2006 Other Health Professional France
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 56 Female 12/13/2006 United States
Primary
Secondary
Staphylococcal Sepsis Hospitalization 10/8/2006 62 Female 154 lb 1/17/2007 Other Health Professional France
Primary
Secondary
Concomitant
Cutaneous Lupus Erythematosus Hospitalization Female 1/19/2007 Other Health Professional France
Primary
Concomitant
Knee Arthroplasty Hospitalization 5/15/2006 46 Female 2/6/2007 Physician Germany
Primary
Concomitant
Prosthesis Implantation Hospitalization 9/13/2005 62 Female 2/14/2007 Other Health Professional Germany
Primary
Concomitant
Neutropenia Hospitalization 11/13/2006 56 Male 2/16/2007 Pharmacist United States
Primary
Secondary
Concomitant
Gallbladder Operation Other Serious Male 190 lb 4/4/2007 Consumer Canada
Primary
Concomitant
Lung Disorder Hospitalization 4/1/2007 Female 4/19/2007 Physician Canada
Primary
Concomitant
Tachycardia Life Threatening 1/21/2006 80 Female 5/11/2007 Other Health Professional France
Primary
Secondary
Neoplasm Skin Hospitalization 2/28/2006 Female 5/18/2007 Other Health Professional France
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 4/1/2007 Female 6/5/2007 Physician Canada
Primary
Concomitant
Oedema Peripheral Hospitalization 10/15/2006 Female 201 lb 6/8/2007 Physician Italy
Primary
Concomitant
Oedema Peripheral Hospitalization 10/15/2006 Female 201 lb 7/5/2007 Physician Italy
Primary
Concomitant
Osteoarthritis Other Serious 11/7/2006 72 Female 7/25/2007 Germany
Primary
Secondary
Gastric Ulcer Hospitalization 7/17/2006 70 Male 7/27/2007 Germany
Primary
Secondary
Dental Prosthesis User Disability Male 7/27/2007 Germany
Primary
Secondary
Uterine Leiomyoma Other Serious 11/26/2005 Female 8/21/2007 Physician United States
Primary
Secondary
Concomitant
Adverse Event Hospitalization Male 10/18/2007 Germany
Primary
Concomitant
Thymus Abscess Hospitalization 53 Female 11/1/2007
Primary
Secondary
Concomitant
Sepsis Life Threatening 3/1/2007 Male 196 lb 11/16/2007 Germany
Primary
Concomitant
Pneumonia Hospitalization Female 199 lb 12/14/2007 United States
Primary
Secondary
Concomitant
Rectosigmoid Cancer Other Serious 4/1/2007 Female 1/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Lung Infiltration Hospitalization 1/7/2008 Female 152 lb 2/5/2008 Germany
Primary
Concomitant
Joint Arthroplasty Hospitalization 8/15/2006 50 Female 2/6/2008 Other Health Professional Germany
Primary
Concomitant
Benign Breast Neoplasm Hospitalization 8/21/2007 58 Female 2/8/2008 Germany
Primary
Secondary
Pneumonia Legionella Hospitalization 7/16/2007 31 Male 2/8/2008 Germany
Primary
Concomitant
Interacting
Intestinal Stenosis Hospitalization 4/2/2007 64 Female 2/8/2008 Germany
Primary
Secondary
Pneumonia Legionella Hospitalization 7/16/2007 31 Male 2/19/2008 Germany
Primary
Concomitant
Interacting
Oedema Peripheral Hospitalization 10/15/2006 Female 201 lb 4/16/2008 Physician Italy
Primary
Concomitant
Hepatitis C Other Serious 62 Female 5/9/2008 Turkey
Primary
Secondary
Concomitant
Weight Increased Hospitalization 7/1/2007 Male 5/21/2008 Germany
Primary
Secondary
Concomitant
Rectosigmoid Cancer Other Serious 4/1/2007 Female 5/28/2008 Other Health Professional France
Primary
Secondary
Concomitant
Hepatitis C Other Serious 62 Female 6/2/2008 Turkey
Primary
Secondary
Concomitant
Weight Increased Hospitalization 7/1/2007 Male 6/6/2008 Germany
Primary
Secondary
Concomitant
Hodgkin's Disease Stage Ii Other Serious 2/21/2008 Female 43 lb 6/5/2008 Physician United States
Primary
Secondary
Concomitant
Hyperplasia Hospitalization 8/21/2007 58 Female 6/30/2008 Germany
Primary
Secondary
Concomitant
Hyperplasia Hospitalization 8/21/2007 58 Female 7/11/2008 Germany
Primary
Secondary
Concomitant
Leukopenia Other Serious 10/15/2007 71 Female 137 lb 8/5/2008 Germany
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 6/22/2006 54 Female 8/6/2008 Germany
Primary
Secondary
Concomitant
Osteoporotic Fracture Hospitalization 4/18/2007 65 Female 8/8/2008 Other Health Professional Germany
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 Male 8/8/2008 Germany
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 12/20/2007 Male 8/8/2008 Physician United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection 12/20/2007 Male 8/14/2008 Physician United Kingdom
Primary
Concomitant
Hodgkin's Disease Other Serious 10 Female 8/18/2008 Physician United States
Primary
Secondary
Weight Increased Hospitalization 7/1/2007 Male 8/19/2008 Germany
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization Female 8/27/2008 United States
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 10 Female 8/28/2008 United States
Primary
Secondary
Concomitant
Progesterone Receptor Assay Positive Other Serious 5/1/2008 Female 9/3/2008 Other Health Professional France
Primary
Secondary
Hyperglycaemia Hospitalization 8/1/2004 Female 9/4/2008 United States
Primary
Secondary
Concomitant
Breast Cancer Hospitalization Female 9/11/2008 Other Health Professional France
Primary
Secondary
Joint Destruction Other Serious 10 Female 9/22/2008 United States
Primary
Secondary
Concomitant
Mouth Ulceration Hospitalization 49 Female 9/25/2008 United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2007 Female 9/26/2008 Physician United States
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 10 Female 9/26/2008 Physician United States
Primary
Secondary
Rheumatoid Nodule Other Serious 11/1/2005 Female 104 lb 9/30/2008 Consumer Brazil
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 10 Female 9/30/2008 Physician United Kingdom
Primary
Secondary
Hodgkin's Disease Other Serious 10 Female 10/2/2008 Other Health Professional United States
Primary
Secondary
Mouth Ulceration Hospitalization 49 Female 10/9/2008 United Kingdom
Primary
Secondary
Concomitant
Herpes Simplex Hospitalization 49 Female 10/14/2008 United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 1/7/2008 Male 10/15/2008 Germany
Primary
Secondary
Concomitant
Wheelchair User Other Serious 10 Female 10/17/2008 Physician United States
Primary
Secondary
Renal Failure Other Serious 4/1/2003 Female 10/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 79 Female 148 lb 10/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 75 Female 148 lb 10/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 10/1/2008 Female 181 lb 11/19/2008 Physician France
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 10/1/2008 Female 181 lb 11/20/2008 Physician France
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 8/1/2004 Female 149 lb 11/20/2008 United States
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 10/1/2008 Female 181 lb 11/28/2008 Physician France
Primary
Secondary
Concomitant
Ileus Hospitalization Female 12/16/2008 Germany
Primary
Concomitant
Intestinal Gangrene Hospitalization 10/3/2008 Female 1/29/2009 Germany
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/9/2008 71 Female 2/4/2009 Germany
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 3/23/2007 Male 2/6/2009 Germany
Primary
Secondary
Concomitant
Cardiac Failure Acute Death Female 2/6/2009 Germany
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/7/2008 Male 2/6/2009 Germany
Primary
Secondary
Concomitant
Arthrodesis Other Serious 8/7/2008 50 Female 2/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Conjunctival Haemorrhage Hospitalization 3/2/2008 64 Female 2/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vestibular Neuronitis Other Serious 4/1/2008 68 Male 2/12/2009 Consumer United Kingdom
Primary
Concomitant
Knee Arthroplasty Hospitalization 2/15/2008 56 Female 2/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Life Threatening 4/18/2008 72 Female 2/12/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pseudomonas Infection Other Serious 1/27/2008 Female 139 lb 3/6/2009 Physician United States
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 7/19/2008 Male 4/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 2 Female 5/8/2009 Other Health Professional United States
Primary
Secondary
Hip Arthroplasty Hospitalization 2/5/2008 72 Female 8/4/2009 Germany
Primary
Concomitant
Lumbar Spinal Stenosis Hospitalization 8/1/2008 78 Female 8/7/2009 Germany
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 117 lb 8/20/2009
Primary
Secondary
Concomitant
Exostosis Hospitalization 1/1/2009 46 Female 8/21/2009 Consumer Germany
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 117 lb 8/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 60 Female 8/20/2009 United Kingdom
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 117 lb 8/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 8/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 117 lb 8/28/2009 Other Health Professional United Arab Emirates
Primary
Secondary
Wound Dehiscence Life Threatening 10/17/2005 67 Male 9/28/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Vestibular Neuronitis Other Serious 4/1/2008 68 Male 10/29/2009 Physician United Kingdom
Primary
Concomitant
Skin Infection Other Serious 8/7/2008 50 Female 10/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 4/1/2007 Female 11/3/2009 Physician France
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Other Serious 1/1/2009 Female 198 lb 11/17/2009 Physician Netherlands
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Other Serious 9/28/2009 Female 198 lb 11/25/2009 Physician Netherlands
Primary
Secondary
Concomitant
Cerebrovascular Accident Life Threatening 4/18/2008 72 Female 12/4/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 70 Male 12/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Aspiration Other Serious 3/23/2007 42 Male 1/7/2010 Germany
Primary
Concomitant
Pneumonia Aspiration Other Serious 3/23/2007 42 Male 1/8/2010 Germany
Primary
Concomitant
Gastric Ulcer Life Threatening 1/1/2007 44 Male 223 lb 1/15/2010 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 3/23/2007 42 Male 1/15/2010 Germany
Primary
Concomitant
Pneumonia Other Serious 3/23/2007 Male 1/15/2010 Germany
Primary
Secondary
Concomitant
Gastric Ulcer Life Threatening 1/1/2007 Male 223 lb 1/21/2010 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/23/2007 Male 1/25/2010 Germany
Primary
Secondary
Concomitant
Wound Dehiscence Life Threatening 10/17/2005 67 Male 2/5/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Inclusion Body Myositis Other Serious 57 Female 2/12/2010 Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 2/10/2009 79 Female 3/11/2010 Germany
Primary
Concomitant
Normal Pressure Hydrocephalus Hospitalization 1/1/2005 74 Female 3/18/2010 Other Health Professional France
Primary
Secondary
Vomiting Other Serious 2/10/2009 79 Female 3/18/2010 Germany
Primary
Concomitant
Coronary Artery Disease Other Serious 78 Male 3/19/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Gastric Ulcer Life Threatening 1/1/2007 44 Male 223 lb 4/20/2010 Physician Germany
Primary
Secondary
Concomitant
Gastric Ulcer Life Threatening 1/1/2007 47 Male 223 lb 4/22/2010 Physician Germany
Primary
Secondary
Concomitant
Leukopenia Other Serious 4/26/2010 Italy
Primary
Secondary
Urticaria Other Serious 4/26/2010 Italy
Primary
Secondary
Hypertriglyceridaemia Other Serious 4/26/2010 Italy
Primary
Secondary
Sepsis Hospitalization 9/1/2009 61 Female 5/13/2010 Germany
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 2/1/2006 48 Female 5/27/2010 Physician United States
Primary
Secondary
Breast Cancer Recurrent Hospitalization 3/9/2007 79 Female 6/16/2010 Physician Germany
Primary
Secondary
Concomitant
Psoriasis Other Serious 52 Male 6/17/2010 Other Health Professional Italy
Primary
Secondary
Interstitial Lung Disease Hospitalization 1/1/2005 52 Male 6/28/2010 France
Primary
Concomitant
Wheezing Other Serious 5/5/2010 67 Female 122 lb 6/28/2010 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 5/5/2010 67 Female 122 lb 7/2/2010 Other Health Professional United States
Primary
Concomitant
Cervical Dysplasia Other Serious 20 Female 7/12/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/1/2006 Female 132 lb 7/19/2010 Physician France
Primary
Secondary
Tenosynovitis Other Serious 47 Female 7/19/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 5/5/2010 67 Female 122 lb 7/28/2010 Other Health Professional United States
Primary
Concomitant
Breast Cancer Recurrent Hospitalization 3/9/2007 79 Female 8/2/2010 Physician Germany
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 55 Female 8/10/2010 Other Health Professional Ireland
Primary
Secondary
Concomitant
Rheumatoid Nodule Hospitalization 12/15/2009 71 Female 9/10/2010 Physician Germany
Primary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 12/23/2009 73 Female 9/23/2010 Physician Germany
Primary
Concomitant
Wrist Fracture Other Serious 6/1/2006 49 Female 150 lb 9/28/2010 Consumer Brazil
Primary
Concomitant
Cervical Dysplasia Hospitalization 20 Female 10/13/2010 Other Health Professional Germany
Primary
Secondary
Rheumatoid Arthritis Other Serious 11/3/2010 Other Health Professional Japan
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 2/1/2009 11/11/2010 Other Health Professional Japan
Primary
Concomitant
Renal Failure Death 11/14/2010 Physician United Kingdom
Primary
Concomitant
Lung Squamous Cell Carcinoma Stage Unspecified Death 1/8/2010 11/16/2010 United Kingdom
Primary
Concomitant
Crohn's Disease Hospitalization 11/17/2010 Other Health Professional Greece
Primary
Concomitant
Lip Neoplasm Malignant Stage Unspecified Other Serious 8/27/2008 11/28/2010 Physician United Kingdom
Primary
Concomitant
Renal Failure Other Serious 1/1/2010 12/1/2010 Physician Germany
Primary
Concomitant
Death Other Serious 77 Female 137 lb 1/3/2011 Physician
Primary
Secondary
Anaphylactic Reaction Other Serious 10 Female 1/13/2011 Physician
Primary
Secondary
Concomitant
Leukopenia Other Serious 7/1/2001 45 Female 152 lb 1/18/2011 Physician United States
Primary
Secondary
Concomitant
Oedematous Pancreatitis Hospitalization 4/30/2010 42 Female 179 lb 1/19/2011 Pharmacist Germany
Primary
Secondary
Concomitant

Drug Data