Erlotinib Hydrochloride combined with Oxycontin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Life Threatening 6/5/2009 70 Female 123 lb 8/20/2009 Physician Japan
Primary
Concomitant
Urine Output Decreased Death 6/19/2009 65 Female 8/28/2009 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 7/1/2009 69 Male 9/4/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 8/8/2009 60 Female 9/9/2009 Physician France
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Life Threatening 6/20/2009 63 Male 107 lb 9/10/2009 Physician Korea, Republic Of
Primary
Concomitant
Aortic Aneurysm Rupture Death 9/4/2009 77 Male 119 lb 9/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neutrophil Count Increased Hospitalization 12/28/2008 53 Female 10/2/2009 Physician United Kingdom
Primary
Concomitant
Syncope Hospitalization 7/27/2009 78 Male 137 lb 10/20/2009 Physician France
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 7/1/2009 69 Male 10/20/2009 Physician Japan
Primary
Concomitant
Pneumothorax Hospitalization 3/5/2009 58 Male 148 lb 10/23/2009 Physician Japan
Primary
Concomitant
Weight Decreased Death 9/4/2009 77 Male 119 lb 10/23/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 6/1/2009 70 Female 117 lb 12/15/2009 Pharmacist Japan
Primary
Concomitant
Pulmonary Hypertension Hospitalization 12/14/2009 70 Female 12/22/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Other Serious 4/1/2008 55 Male 137 lb 12/18/2009 Physician Japan
Primary
Concomitant
Pulmonary Hypertension Hospitalization 12/14/2009 70 Female 1/15/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 10/25/2009 48 Female 1/15/2010 Other Health Professional United States
Primary
Concomitant
Rash Life Threatening 11/2/2009 64 Male 1/26/2010 Physician Japan
Primary
Concomitant
Leukoencephalopathy Other Serious 1/6/2009 62 Male 1/29/2010 Physician Japan
Primary
Secondary
Concomitant
Malignant Pleural Effusion Death 4/1/2008 57 Male 2/2/2010 Physician Japan
Primary
Concomitant
Non-small Cell Lung Cancer Stage Iv Hospitalization 8/20/2007 52 Male 2/26/2010 Physician Korea, Republic Of
Primary
Concomitant
Pneumonia Other Serious 9/18/2009 65 Male 128 lb 2/26/2010 Physician Japan
Primary
Secondary
Concomitant
Melaena Other Serious 1/6/2009 62 Male 133 lb 3/12/2010 Physician Japan
Primary
Secondary
Concomitant
Thirst Hospitalization 2/11/2009 74 Male 146 lb 3/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Occult Blood Positive Other Serious 1/6/2009 62 Male 133 lb 3/23/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 1/6/2009 62 Male 133 lb 4/9/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 3/24/2010 58 Female 134 lb 4/29/2010 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/3/2008 57 Male 150 lb 5/10/2010 Other Health Professional United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 5/7/2010 73 Male 126 lb 5/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 5/7/2010 73 Male 126 lb 5/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/7/2010 73 Male 126 lb 5/21/2010 Physician United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 3/24/2010 58 Female 134 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Gastric Cancer Other Serious 10/15/2009 68 Male 117 lb 6/17/2010 Physician Japan
Primary
Concomitant
Tachypnoea Life Threatening 1/21/2008 62 Male 7/6/2010 Other Health Professional Canada
Primary
Concomitant
Rash Other Serious 9/18/2009 65 Male 128 lb 7/9/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Shock Hospitalization 1/28/2009 73 Male 115 lb 7/15/2010 Other Health Professional Japan
Primary
Concomitant
Metastases To Bone Hospitalization 1/31/2009 80 Male 93 lb 7/16/2010 Physician Japan
Primary
Concomitant
Shock Hospitalization 1/28/2009 72 Male 115 lb 7/26/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Death 1/9/2009 61 Female 99 lb 8/19/2010 Physician Jamaica
Primary
Concomitant
Rash Death 2/5/2009 31 Male 124 lb 8/19/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2007 64 Female 161 lb 9/1/2010 Lawyer United States
Primary
Concomitant
Haemoptysis Hospitalization 4/21/2008 64 Female 9/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 6/29/2009 65 Female 97 lb 9/15/2010 Other Health Professional Japan
Primary
Concomitant
Rash Other Serious 2/5/2009 31 124 lb 9/28/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Pseudomonas Infection Hospitalization 12/19/2008 67 Female 102 lb 9/28/2010 Other Health Professional Japan
Primary
Concomitant
Syncope Life Threatening 12/9/2008 73 Male 126 lb 10/6/2010 Physician Japan
Primary
Concomitant
Pseudomonas Infection Hospitalization 12/19/2008 67 Female 102 lb 11/2/2010 Other Health Professional Japan
Primary
Concomitant
Staphylococcus Test Positive Other Serious 7/1/2009 69 Male 11/2/2010 Other Health Professional Japan
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2005 40 Male 11/15/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 11/1/2007 64 Female 161 lb 11/22/2010 Lawyer United States
Primary
Concomitant
Non-small Cell Lung Cancer Stage Iiib Other Serious 10/15/2009 68 Male 117 lb 11/22/2010 Physician Japan
Primary
Concomitant
Syncope Life Threatening 11/20/2008 73 Male 126 lb 11/23/2010 Other Health Professional Japan
Primary
Concomitant
Non-small Cell Lung Cancer Metastatic Other Serious 83 Female 103 lb 11/23/2010 Other Health Professional Japan
Primary
Concomitant
Stress Urinary Incontinence Hospitalization 11/17/2010 73 Female 152 lb 12/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Metastatic Other Serious 1/31/2009 51 Male 120 lb 12/14/2010 Other Health Professional Japan
Primary
Concomitant
Urinary Incontinence Hospitalization 11/17/2010 73 Female 152 lb 12/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Gastritis Other Serious 83 Female 103 lb 1/26/2011 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 3/26/2011 55 Male 218 lb 4/4/2011 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 3/26/2011 55 Male 4/11/2011 Physician United States
Primary
Secondary
Concomitant
Antibiotic Resistant Staphylococcus Test Positive Hospitalization 3/1/2011 47 Female 111 lb 4/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 4/4/2011 67 Male 5/4/2011 Physician Japan
Primary
Concomitant
Death Death Male 5/23/2011 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 2/7/2011 72 Female 124 lb 2/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 1/1/2005 40 Male 6/7/2011 Lawyer United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 12/19/2008 67 Female 101 lb 6/4/2011 Physician Japan
Primary
Concomitant
Large Intestine Perforation Hospitalization 2/1/2011 66 Male 6/17/2011 Physician Denmark
Primary
Concomitant
Renal Failure Hospitalization 2/3/2011 63 Male 161 lb 7/22/2011 Physician France
Primary
Secondary
Concomitant
Metastases To Bone Other Serious 1/1/2005 40 Male 8/1/2011 Lawyer United States
Primary
Concomitant
Transfusion Other Serious 7/19/2011 56 Female 8/16/2011 Consumer United States
Primary
Concomitant
Death Death 8/23/2011 36 Male 8/26/2011 Physician United States
Primary
Concomitant
Fatigue Other Serious 7/19/2011 56 Female 9/2/2011 Pharmacist United States
Primary
Concomitant
Mental Status Changes Hospitalization 9/5/2011 66 Male 136 lb 9/6/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Urosepsis Hospitalization 9/5/2011 66 Male 137 lb 9/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 9/12/2011 53 Male 9/16/2011 Other Health Professional United States
Primary
Concomitant
Urosepsis Hospitalization 9/5/2011 66 Male 137 lb 9/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Anaemia Death 9/8/2011 44 Female 9/19/2011 Pharmacist United States
Primary
Concomitant
Drug Dose Omission Hospitalization 9/5/2011 66 Male 136 lb 9/16/2011 Consumer United States
Primary
Secondary
Concomitant
Femur Fracture Hospitalization 9/9/2011 77 Female 9/23/2011 Consumer United States
Primary
Concomitant
Epilepsy Hospitalization 4/1/2011 43 Female 9/28/2011 Consumer China
Primary
Concomitant
Disease Progression Hospitalization 9/5/2011 66 Male 134 lb 9/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Cancer Metastatic Death 9/12/2011 53 Male 10/3/2011 Other Health Professional United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 9/5/2011 66 Male 132 lb 10/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 10/12/2011 56 Female 10/17/2011 Pharmacist United States
Primary
Concomitant
Coma Hospitalization 4/1/2011 43 Female 117 lb 10/20/2011 Consumer China
Primary
Concomitant
General Physical Health Deterioration Other Serious 2/3/2011 63 Male 161 lb 10/24/2011 Consumer France
Primary
Secondary
Concomitant
Disease Progression Death Male 10/24/2011 Physician United States
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 9/5/2011 66 Male 137 lb 10/25/2011 Physician United States
Primary
Secondary
Concomitant
Fatigue Other Serious 7/19/2011 56 Female 11/2/2011 Pharmacist United States
Primary
Concomitant
Diarrhoea Death 9/22/2011 68 Male 11/7/2011 Consumer United States
Primary
Concomitant
Metabolic Encephalopathy Hospitalization 9/5/2011 66 Male 137 lb 11/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 10/24/2011 63 Female 11/18/2011 Physician France
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 9/23/2011 50 Female 11/21/2011 Other Health Professional United States
Primary
Concomitant
Dyspnoea Hospitalization 10/24/2011 63 Female 11/29/2011 Physician France
Primary
Secondary
Concomitant
Off Label Use Hospitalization 9/23/2011 50 Female 12/8/2011 Physician United States
Primary
Concomitant
Blood Calcium Decreased Hospitalization 11/5/2011 59 Male 141 lb 12/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Abnormal Faeces Hospitalization 1/1/2011 77 Female 12/16/2011 Pharmacist United States
Primary
Concomitant
General Physical Health Deterioration Death 4/18/2011 81 Female 12/19/2011 Physician France
Primary
Concomitant
Death Death 12/1/2011 44 Female 12/27/2011 Consumer United States
Primary
Secondary
Concomitant
C-reactive Protein Increased Other Serious 9/6/2011 51 Female 108 lb 12/30/2011 Physician Japan
Primary
Secondary
Concomitant
Death Death 12/25/2011 79 Male 12/30/2011 Pharmacist United States
Primary
Concomitant
Death Death Female 1/17/2012 United States
Primary
Secondary
Concomitant
Rash Death 11/18/2011 77 Male 1/17/2012 Consumer United States
Primary
Concomitant
Death Death Female 1/20/2012 Pharmacist United States
Primary
Concomitant
Pneumonia Bacterial Hospitalization 9/16/2011 78 Male 121 lb 1/25/2012 Physician Japan
Primary
Secondary
Concomitant
Embolism Hospitalization 10/17/2011 63 Male 141 lb 1/30/2012 Physician Japan
Primary
Concomitant
Neoplasm Malignant Death Male 1/27/2012 Pharmacist United States
Primary
Concomitant
Bronchitis Other Serious 4/23/2008 58 Male 134 lb 2/1/2012 Other Health Professional Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 10/31/2011 77 Male 2/10/2012 Physician Japan
Primary
Concomitant
Bronchial Carcinoma Death Female 2/17/2012 Pharmacist United States
Primary
Concomitant
Cholangitis Other Serious 9/6/2011 51 Female 108 lb 2/22/2012 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/10/2011 63 Male 132 lb 2/24/2012 Physician Japan
Primary
Secondary
Concomitant
Death Death Male 2/27/2012 Pharmacist United States
Primary
Concomitant
C-reactive Protein Increased Other Serious 9/6/2011 51 Female 108 lb 2/29/2012 Physician Japan
Primary
Secondary
Concomitant
Death Death 2/27/2012 60 Female 3/9/2012 Pharmacist United States
Primary
Concomitant
Pancreatic Carcinoma Stage Iv Death Male 3/15/2012 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 1/23/2012 66 Female 3/19/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 9/24/2011 77 Male 3/19/2012 Physician Japan
Primary
Concomitant
Death Death 1/1/2012 56 Male 3/20/2012 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Death 11/8/2011 66 Male 97 lb 3/27/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Hilar Lymphadenopathy Hospitalization 1/1/2012 52 Male 256 lb 3/28/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Failure Death Male 4/16/2012 Pharmacist United States
Primary
Concomitant
Depression Hospitalization 3/1/2012 52 Male 4/18/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 12/5/2011 70 Male 4/18/2012 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 1/1/2012 Male 4/27/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 1/23/2012 66 Female 5/4/2012 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Hilar Enlargement Other Serious 1/1/2012 52 Male 5/4/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 4/21/2012 59 Male 5/14/2012 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 12/10/2011 63 Male 132 lb 5/18/2012 Physician Japan
Primary
Secondary
Concomitant
Depression Hospitalization 3/1/2012 52 Male 251 lb 5/22/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Performance Status Decreased Death 12/1/2011 44 Female 5/25/2012 Consumer United States
Primary
Secondary
Concomitant
Dermatitis Bullous Death 11/10/2011 67 Male 5/25/2012 Pharmacist United States
Primary
Concomitant
Blood Bilirubin Increased Death 5/10/2012 51 Female 5/30/2012 Physician Japan
Primary
Secondary
Concomitant
Haematuria Hospitalization 2/5/2012 63 Male 121 lb 6/4/2012 Physician Japan
Primary
Secondary
Concomitant
Device Related Infection Other Serious 4/5/2012 56 Female 143 lb 6/7/2012 Physician Japan
Primary
Secondary
Concomitant
Death Death 5/1/2012 40 Male 6/8/2012 Pharmacist United States
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 4/13/2012 49 Male 126 lb 6/11/2012 Physician Japan
Primary
Secondary
Concomitant
Death Death 4/21/2012 63 Female 6/15/2012 Pharmacist United States
Primary
Concomitant
Neoplasm Malignant Death Female 6/25/2012 Pharmacist United States
Primary
Concomitant
Deep Vein Thrombosis Other Serious 10/17/2011 63 Male 141 lb 6/28/2012 Physician Japan
Primary
Concomitant
Hyperglycaemia Other Serious 2/21/2012 40 Male 7/2/2012 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Hospitalization 1/1/2012 74 Male 7/5/2012 Physician Japan
Primary
Secondary
Concomitant
Pancreatic Pseudocyst Death 6/1/2012 64 Male 7/10/2012 Physician Japan
Primary
Concomitant
Neoplasm Malignant Death Female 7/10/2012 Pharmacist United States
Primary
Concomitant
Dermatitis Acneiform Death 7/22/2011 37 Female 7/19/2012 Other Health Professional United States
Primary
Concomitant
Stomatitis Other Serious 1/1/2012 66 Female 7/26/2012 Physician Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 5/10/2012 51 Female 7/26/2012 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 4/18/2011 81 Female 7/27/2012 Physician France
Primary
Concomitant
Diarrhoea Other Serious 4/5/2012 56 Female 143 lb 7/30/2012 Physician Japan
Primary
Secondary
Concomitant
Rash Pruritic Death 6/1/2012 72 Female 146 lb 8/7/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoalbuminaemia Hospitalization 2/5/2012 63 Male 121 lb 8/9/2012 Physician Japan
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 10/24/2011 72 Male 8/9/2012 Physician Japan
Primary
Secondary
Concomitant

Drug Data