Erlotinib Hydrochloride combined with Omeprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pneumothorax Hospitalization 7/21/2009 65 Male 121 lb 8/12/2009 Physician Spain
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 6/13/2009 65 Female 9/4/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/8/2009 60 Female 9/9/2009 Physician France
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 6/16/2009 76 Male 176 lb 9/22/2009 Physician Japan
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 8/26/2009 66 Female 9/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Hospitalization 7/4/2009 41 Male 9/29/2009 Other Health Professional Japan
Primary
Concomitant
Sudden Death Death 1/29/2009 67 Male 148 lb 9/29/2009 Physician Poland
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 12/26/2008 61 Female 98 lb 10/2/2009 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 8/4/2009 74 Male 10/2/2009 Other Health Professional Japan
Primary
Concomitant
Sudden Death Death 1/29/2009 67 Male 148 lb 10/20/2009 Physician Poland
Primary
Secondary
Concomitant
Syncope Hospitalization 7/27/2009 78 Male 137 lb 10/20/2009 Physician France
Primary
Secondary
Concomitant
Musculoskeletal Chest Pain Hospitalization 9/8/2009 64 Male 10/30/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Death 7/17/2009 56 Male 177 lb 11/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 8/11/2009 80 Male 11/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
C-reactive Protein Increased Hospitalization 6/16/2009 76 Male 176 lb 11/10/2009 Physician Japan
Primary
Concomitant
Weight Decreased Hospitalization 8/11/2009 80 Male 11/23/2009 Physician United Kingdom
Primary
Concomitant
Non-small Cell Lung Cancer Metastatic Hospitalization 8/19/2008 64 Male 134 lb 12/1/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 5/5/2009 69 Female 12/1/2009 Physician Singapore
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 2/6/2009 47 Male 192 lb 12/1/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cells Urine Positive Death 11/11/2009 75 Male 212 lb 12/4/2009 Physician United States
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 7/21/2009 65 Male 121 lb 12/15/2009 Spain
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 5/4/2009 69 Female 12/18/2009 Physician Singapore
Primary
Secondary
Concomitant
Sepsis Hospitalization 11/29/2009 61 Male 12/22/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 11/11/2009 75 Male 212 lb 12/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/18/2009 65 Male 128 lb 2/26/2010 Physician Japan
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 4/6/2008 80 Female 2/26/2010 Physician United Kingdom
Primary
Concomitant
Platelet Count Decreased Other Serious 12/26/2008 61 Female 98 lb 3/5/2010 Other Health Professional Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 2/6/2009 47 Male 192 lb 3/9/2010 Other Health Professional Japan
Primary
Concomitant
Thirst Hospitalization 2/11/2009 74 Male 146 lb 3/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oral Herpes Hospitalization 7/1/2009 41 Male 117 lb 4/2/2010 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 6/16/2009 76 Male 176 lb 4/6/2010 Physician Japan
Primary
Concomitant
Hyponatraemia Other Serious 2/6/2009 47 Male 192 lb 4/23/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 9/3/2008 57 Male 150 lb 5/10/2010 Other Health Professional United States
Primary
Concomitant
Somnolence Hospitalization 3/2/2010 56 Male 5/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 11/3/2009 79 Female 5/17/2010 Physician United States
Primary
Concomitant
Renal Failure Acute Life Threatening 7/8/2008 77 Male 142 lb 5/24/2010 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 5/5/2010 65 Male 6/15/2010 Physician United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 11/3/2009 79 Female 6/21/2010 Physician United States
Primary
Concomitant
Ulcer Hospitalization 3/22/2010 44 Male 6/28/2010 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 5/18/2010 62 Male 7/6/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ulcer Hospitalization 3/22/2010 44 Male 7/6/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Rash Other Serious 9/18/2009 65 Male 128 lb 7/9/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Troponin Increased Death 6/20/2010 66 Male 172 lb 7/15/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/8/2008 77 Male 142 lb 7/21/2010 Physician Japan
Primary
Secondary
Concomitant
Blindness Hospitalization 10/3/2008 70 Male 112 lb 8/16/2010 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/17/2008 56 Female 8/20/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 10/21/2008 67 Female 130 lb 8/23/2010 Physician Poland
Primary
Secondary
Concomitant
Death Death 1/29/2009 67 Male 148 lb 8/24/2010 Physician Poland
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Hospitalization 8/19/2008 64 Male 134 lb 8/24/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 12/10/2008 59 Female 168 lb 8/24/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
Pneumonia Life Threatening 6/12/2010 80 Male 8/20/2010 Other Health Professional United States
Primary
Concomitant
Blindness Hospitalization 10/3/2008 70 Male 8/25/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 6/12/2010 80 Male 9/10/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 12/10/2008 59 Female 168 lb 9/10/2010 Other Health Professional Poland
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/7/2008 62 Female 121 lb 9/10/2010 Physician Chile
Primary
Secondary
Concomitant
Stomatitis Hospitalization 6/1/2010 74 Female 9/17/2010 Consumer United States
Primary
Secondary
Concomitant
Stomatitis Hospitalization 6/16/2009 76 Male 176 lb 9/20/2010 Other Health Professional Japan
Primary
Concomitant
Non-small Cell Lung Cancer Death 9/17/2010 65 10/13/2010 Physician Spain
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/27/2010 73 Female 174 lb 10/26/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 7/21/2009 65 Male 121 lb 11/2/2010 Physician Spain
Primary
Secondary
Concomitant
Vomiting Other Serious 9/22/2010 75 Female 11/22/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 5/27/2010 64 Male 12/3/2010 Other Health Professional France
Primary
Concomitant
Ulcer Hospitalization 3/22/2010 44 Male 150 lb 12/15/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Skin Toxicity Hospitalization 11/3/2009 56 Male 130 lb 12/16/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Reflux Oesophagitis Hospitalization 7/11/2008 58 Male 110 lb 2/10/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Chest Pain Life Threatening 12/15/2010 64 Male 2/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 3/25/2011 68 Female 132 lb 5/4/2011 Physician United States
Primary
Secondary
Concomitant
Death Death 5/20/2011 75 Female 5/27/2011 Physician United States
Primary
Concomitant
Pneumothorax Hospitalization 7/21/2009 65 Male 121 lb 5/17/2011 Physician Spain
Primary
Secondary
Concomitant
Gastrointestinal Disorder Hospitalization 8/23/2009 57 Female 5/19/2011 Other Health Professional India
Primary
Concomitant
Haemoptysis Death 9/17/2010 65 Male 5/31/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Metastatic Death 3/1/2009 72 Male 6/3/2011 Physician Brazil
Primary
Secondary
Concomitant
Death Death 6/14/2011 67 Female 6/17/2011 Physician United States
Primary
Concomitant
Hypoxia Death 5/20/2011 75 Female 6/27/2011 Other Health Professional United States
Primary
Concomitant
Death Death 5/24/2011 56 Male 6/30/2011 Physician United States
Primary
Concomitant
Death Death 6/29/2011 72 Male 7/1/2011 Physician United States
Primary
Concomitant
Non-small Cell Lung Cancer Death 6/14/2011 67 Female 7/1/2011 Other Health Professional United States
Primary
Concomitant
General Physical Health Deterioration Hospitalization 3/28/2011 63 Male 187 lb 7/11/2011 Physician France
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 6/1/2011 86 Male 7/8/2011 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 3/25/2011 68 Female 132 lb 6/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 7/13/2011 52 Male 7/18/2011 Physician United States
Primary
Concomitant
General Physical Health Deterioration Other Serious 3/28/2011 63 Male 187 lb 7/25/2011 Physician France
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 3/25/2011 68 Female 132 lb 7/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 4/28/2011 71 Male 8/1/2011 Consumer United States
Primary
Concomitant
Atelectasis Hospitalization 9/27/2010 65 Female 161 lb 7/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 7/22/2011 75 Female 8/3/2011 Physician United States
Primary
Concomitant
Disease Progression Death Male 8/22/2011 Physician United States
Primary
Concomitant
Pseudomonas Infection Hospitalization 9/27/2010 65 Female 161 lb 8/24/2011 Physician United States
Primary
Secondary
Concomitant
Rales Hospitalization 7/13/2011 54 Male 225 lb 8/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hospice Care Life Threatening Male 9/2/2011 Physician United States
Primary
Concomitant
Ascites Hospitalization 3/28/2011 63 Male 187 lb 9/13/2011 Physician France
Primary
Secondary
Concomitant
Death Death 9/9/2011 63 Male 9/16/2011 Physician United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 5/4/2011 58 Male 9/19/2011 Physician France
Primary
Secondary
Concomitant
Nausea Hospitalization 7/22/2011 75 Female 9/20/2011 Physician United States
Primary
Concomitant
Death Death 9/23/2011 66 Male 9/30/2011 Pharmacist United States
Primary
Concomitant
Non-small Cell Lung Cancer Metastatic Death Male 10/17/2011 Other Health Professional United States
Primary
Concomitant
Pyrexia Death 7/26/2011 75 Female 10/19/2011 Physician Japan
Primary
Secondary
Concomitant
Somnolence Hospitalization 54 Male 10/24/2011 Physician Spain
Primary
Concomitant
Interacting
Somnolence Hospitalization 54 Male 10/28/2011 Physician United States
Primary
Concomitant
Interacting
Disease Progression Death 67 Male 10/31/2011 Physician United States
Primary
Secondary
Concomitant
Death Death 10/26/2011 70 Female 10/31/2011 Pharmacist United States
Primary
Concomitant
Death Death 10/31/2011 67 Female 11/7/2011 Pharmacist United States
Primary
Concomitant
Perirectal Abscess Life Threatening 7/21/2010 68 Male 110 lb 11/11/2011 Physician France
Primary
Secondary
Concomitant
Somnolence Hospitalization 54 Male 11/15/2011 Physician Spain
Primary
Concomitant
Interacting
Dyspnoea Hospitalization 10/24/2011 63 Female 11/18/2011 Physician France
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 9/23/2011 50 Female 11/21/2011 Other Health Professional United States
Primary
Concomitant
Death Death 9/14/2011 64 Male 11/21/2011 Consumer United States
Primary
Concomitant
Diarrhoea Other Serious 8/14/2011 56 Female 88 lb 11/28/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Death Male 11/29/2011 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 10/24/2011 63 Female 11/29/2011 Physician France
Primary
Secondary
Concomitant
Off Label Use Hospitalization 9/23/2011 50 Female 12/8/2011 Physician United States
Primary
Concomitant
Death Death 12/3/2011 61 Female 12/23/2011 Pharmacist United States
Primary
Concomitant
Respiratory Disorder Hospitalization 9/21/2009 60 Male 150 lb 12/20/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Death Death Female 12/29/2011 Pharmacist United States
Primary
Concomitant
Death Death 12/13/2011 81 Male 12/30/2011 Pharmacist United States
Primary
Concomitant
Off Label Use Other Serious 10/28/2011 75 Female 194 lb 12/30/2011 Physician United States
Primary
Secondary
Concomitant
Death Death Female 1/9/2012 Consumer United States
Primary
Concomitant
Incorrect Dose Administered Death 11/9/2011 63 Male 1/6/2012 Pharmacist United States
Primary
Concomitant
Incorrect Dose Administered Death Male 1/13/2012 Pharmacist United States
Primary
Concomitant
Disease Progression Death 67 Male 1/17/2012 Physician United States
Primary
Secondary
Concomitant
Anaphylactic Shock Other Serious 8/14/2011 56 Female 88 lb 1/18/2012 Physician Japan
Primary
Secondary
Concomitant
Death Death Female 1/20/2012 Pharmacist United States
Primary
Concomitant
Death Other Serious 11/1/2011 40 Male 1/23/2012 Other Health Professional United States
Primary
Concomitant
Mucosal Inflammation Hospitalization 9/21/2009 60 Male 150 lb 1/25/2012 Physician Spain
Primary
Secondary
Concomitant
Anaphylactic Shock Other Serious 8/14/2011 56 Female 88 lb 1/30/2012 Physician Japan
Primary
Secondary
Concomitant
Death Death 1/2/2012 65 Female 126 lb 1/31/2012 Pharmacist United States
Primary
Concomitant
Pneumonia Hospitalization 1/14/2012 74 Male 2/6/2012 Physician Germany
Primary
Secondary
Dermatitis Bullous Other Serious 11/1/2011 40 Male 2/9/2012 Other Health Professional United States
Primary
Concomitant
Bronchial Carcinoma Death Female 2/17/2012 Pharmacist United States
Primary
Concomitant
Neoplasm Malignant Death Female 126 lb 2/17/2012 Pharmacist United States
Primary
Concomitant
Diarrhoea Hospitalization 9/21/2009 60 Male 150 lb 2/23/2012 Other Health Professional Spain
Primary
Secondary
Concomitant
Death Death Male 2/27/2012 Pharmacist United States
Primary
Concomitant
Death Death Male 2/27/2012 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 12/15/2011 58 Male 2/21/2012 Physician United Kingdom
Primary
Concomitant
Anaemia Other Serious 11/24/2011 82 Female 88 lb 2/29/2012 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 1/14/2012 74 Male 3/5/2012 Physician Germany
Primary
Secondary
Platelet Count Increased Hospitalization 1/12/2012 61 Male 3/7/2012 Physician Japan
Primary
Concomitant
Transient Ischaemic Attack Other Serious 2/11/2012 77 Male 3/8/2012 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatic Carcinoma Stage Iv Death Male 3/15/2012 Physician United States
Primary
Concomitant
Death Death Female 3/19/2012 Pharmacist United States
Primary
Concomitant
Diarrhoea Hospitalization 1/23/2012 66 Female 3/19/2012 Physician Japan
Primary
Secondary
Concomitant
Death Death 4/5/2012 66 Female 4/13/2012 Pharmacist United States
Primary
Concomitant
Death Death 3/3/2012 73 Female 4/13/2012 Consumer United States
Primary
Concomitant
Cor Pulmonale Other Serious 11/24/2011 82 Female 88 lb 4/16/2012 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/12/2012 61 Male 4/19/2012 Physician Japan
Primary
Concomitant
Death Death 4/9/2012 84 Male 4/19/2012 Pharmacist United States
Primary
Concomitant
Death Death 3/30/2012 68 Female 4/30/2012 Pharmacist United States
Primary
Concomitant
Neoplasm Malignant Death Male 5/4/2012 Pharmacist United States
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 1/23/2012 66 Female 5/4/2012 Physician Japan
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 2/1/2012 42 Female 110 lb 5/4/2012 Other Health Professional United States
Primary
Concomitant

Drug Data