Erlotinib Hydrochloride combined with Gemcitabine Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Other Serious 12/8/2009 61 Female 3/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/25/2010 55 Male 3/23/2010 Other Health Professional United States
Primary
Secondary
Platelet Count Decreased Hospitalization 3/30/2010 50 Female 4/28/2010 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 5/2/2010 66 Female 5/14/2010 Physician United States
Primary
Secondary
Muscle Spasms Other Serious 7/6/2010 72 Male 7/21/2010 Other Health Professional United States
Primary
Secondary
Pneumonia Other Serious 7/6/2010 72 Male 8/4/2010 Physician United States
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 5/2/2010 66 Female 8/4/2010 Physician United States
Primary
Secondary
Ventricular Fibrillation Other Serious 7/13/2010 71 Male 8/16/2010 Other Health Professional United States
Primary
Secondary
Renal Failure Other Serious 5/21/2010 61 Female 154 lb 8/18/2010 Physician United States
Primary
Secondary
Concomitant
Troponin Increased Other Serious 8/3/2010 69 Female 9/10/2010 Physician United States
Primary
Secondary
Respiratory Failure Other Serious 7/13/2010 71 Male 9/20/2010 Other Health Professional United States
Primary
Secondary
Neoplasm Malignant Hospitalization 63 Female 3/4/2011 Physician Germany
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 49 Male 4/14/2011 Physician United States
Primary
Concomitant
Cellulitis Other Serious 5/19/2011 Physician United States
Primary
Concomitant
Neutropenia Hospitalization 6/1/2011 69 Male 126 lb 6/24/2011 Other Health Professional United States
Primary
Secondary
Neutropenia Hospitalization 6/1/2011 69 Male 126 lb 7/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Hospitalization 3/23/2010 62 Male 7/27/2011 Consumer United States
Primary
Secondary
Hypokalaemia Death 8/9/2011 78 Male 115 lb 8/17/2011 Physician United States
Primary
Secondary
Concomitant
Death Death 8/9/2011 78 Male 115 lb 9/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Death 11/1/2007 73 Male 130 lb 10/7/2011 Physician Korea, Republic Of
Primary
Secondary
Pyrexia Other Serious 1/1/2011 77 Female 10/12/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 9/20/2011 61 Male 10/13/2011 Physician Japan
Primary
Concomitant
Pyrexia Death 7/26/2011 75 Female 10/19/2011 Physician Japan
Primary
Secondary
Concomitant
Hyponatraemia Death 1/1/2011 57 Female 163 lb 10/20/2011 Other Health Professional United States
Primary
Secondary
Death Death 10/21/2011 Physician Korea, Republic Of
Primary
Concomitant
Death Death 10/21/2011 Physician Korea, Republic Of
Primary
Concomitant
Death Other Serious 10/21/2011 Physician Korea, Republic Of
Primary
Concomitant
Death Death 10/21/2011 Physician Korea, Republic Of
Primary
Concomitant
Dermatitis Acneiform Other Serious 9/20/2011 61 Male 10/21/2011 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 10/1/2011 71 Male 174 lb 10/27/2011 Physician Spain
Primary
Secondary
Concomitant
Neoplasm Progression Other Serious 54 10/28/2011 Consumer Switzerland
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 10/31/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Pneumonia Aspiration Other Serious 10/31/2011 77 Male 11/9/2011 Physician Japan
Primary
Concomitant
Dermatitis Acneiform Other Serious 54 11/10/2011 Consumer Switzerland
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/1/2011 71 Male 174 lb 11/10/2011 Physician Spain
Primary
Secondary
Concomitant
Headache Death 60 Female 11/10/2011 Other Health Professional Italy
Primary
Secondary
Lung Disorder Other Serious 11/22/2011 Other Health Professional Japan
Primary
Secondary
Fatigue Hospitalization 9/26/2011 57 Female 117 lb 11/22/2011 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Other Serious 1/1/2011 77 Female 11/28/2011 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 8/14/2011 56 Female 88 lb 11/28/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Other Serious 54 12/12/2011 Physician Switzerland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/13/2011 78 Female 101 lb 12/21/2011 Physician Japan
Primary
Secondary
Concomitant
Anaemia Other Serious 10/12/2011 73 Female 90 lb 12/30/2011 Physician Japan
Primary
Secondary
Decreased Appetite Other Serious 9/26/2011 57 Female 117 lb 1/3/2012 Physician Japan
Primary
Secondary
Concomitant
Laboratory Test Abnormal Other Serious 1/1/2011 77 Female 1/12/2012 Physician Japan
Primary
Concomitant
Anaphylactic Shock Other Serious 8/14/2011 56 Female 88 lb 1/18/2012 Physician Japan
Primary
Secondary
Concomitant
C-reactive Protein Increased Other Serious 10/25/2011 53 Male 1/24/2012 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 11/7/2011 76 Male 157 lb 1/30/2012 Physician Japan
Primary
Secondary
Concomitant
Embolism Hospitalization 10/17/2011 63 Male 141 lb 1/30/2012 Physician Japan
Primary
Concomitant
Anaphylactic Shock Other Serious 8/14/2011 56 Female 88 lb 1/30/2012 Physician Japan
Primary
Secondary
Concomitant
Acidosis Other Serious 11/27/2011 67 Male 112 lb 2/3/2012 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 10/31/2011 77 Male 2/10/2012 Physician Japan
Primary
Concomitant
Diarrhoea Hospitalization 10/13/2011 78 Female 101 lb 2/14/2012 Physician Japan
Primary
Secondary
Concomitant
Choking Other Serious 2/19/2011 71 Male 143 lb 2/15/2012 Physician Taiwan, Province Of China
Primary
Secondary
Interstitial Lung Disease Hospitalization 59 Male 2/20/2012 Other Health Professional Israel
Primary
Secondary
Gastric Haemorrhage Death 11/27/2011 67 Male 112 lb 2/24/2012 Physician Japan
Primary
Secondary
Concomitant
Bile Duct Obstruction Hospitalization 2/7/2012 71 Male 152 lb 3/5/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Posterior Reversible Encephalopathy Syndrome Other Serious 50 Female 3/6/2012 Physician United States
Primary
Concomitant
Platelet Count Increased Hospitalization 1/12/2012 61 Male 3/7/2012 Physician Japan
Primary
Concomitant
Anaemia Other Serious 1/23/2012 69 Male 3/9/2012 Physician Japan
Primary
Secondary
Concomitant
Lung Disorder Other Serious 3/16/2012 Other Health Professional Japan
Primary
Secondary
Posterior Reversible Encephalopathy Syndrome Hospitalization 50 Female 3/14/2012 Physician United States
Primary
Secondary
Diarrhoea Hospitalization 1/23/2012 66 Female 3/19/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Aspiration Death 9/24/2011 77 Male 3/19/2012 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 11/7/2011 76 Male 157 lb 3/20/2012 Physician Japan
Primary
Secondary
Concomitant
Small Intestinal Haemorrhage Other Serious 3/23/2012 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Death 3/23/2012 Physician United States
Primary
Concomitant
Pulmonary Embolism Death 3/23/2012 Physician Spain
Primary
Concomitant
Septic Shock Death 3/23/2012 Physician Spain
Primary
Concomitant
Cholangitis Death 3/23/2012 Physician Spain
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 3/10/2012 71 Male 3/26/2012 Physician Japan
Primary
Concomitant
Sepsis Hospitalization 2/1/2012 71 Male 152 lb 3/27/2012 Consumer United States
Primary
Secondary
Concomitant
Cholangitis Other Serious 1/1/2011 54 Male 121 lb 3/27/2012 Physician Japan
Primary
Concomitant
Dermatitis Acneiform Other Serious 2/13/2012 71 Male 134 lb 3/28/2012 Physician Japan
Primary
Concomitant
Ischaemic Ulcer Hospitalization 3/11/2012 74 Male 150 lb 3/29/2012 Physician Spain
Primary
Secondary
Thrombosis Other Serious 3/30/2012 Physician United States
Primary
Concomitant
Thrombosis Other Serious 3/30/2012 Physician United States
Primary
Concomitant
Thrombosis Other Serious 3/30/2012 Physician United States
Primary
Concomitant
Epistaxis Other Serious 54 Female 3/30/2012 Taiwan, Province Of China
Primary
Secondary
Anaemia Other Serious 8/4/2011 78 Female 4/2/2012 Physician Japan
Primary
Concomitant
Inappropriate Schedule Of Drug Administration Hospitalization 12/29/2011 47 Female 123 lb 4/6/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 3/10/2012 71 Male 4/6/2012 Physician Japan
Primary
Concomitant
Cholangitis Other Serious 10/25/2011 53 Male 137 lb 4/12/2012 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 12/5/2011 70 Male 4/18/2012 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/12/2012 61 Male 4/19/2012 Physician Japan
Primary
Concomitant
Small Intestinal Haemorrhage Life Threatening 4/20/2012 Physician United States
Primary
Concomitant
Neoplasm Progression Disability 52 Male 4/27/2012 Other Health Professional Greece
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 1/23/2012 66 Female 5/4/2012 Physician Japan
Primary
Secondary
Concomitant
Bile Duct Stenosis Other Serious 2/13/2012 71 Male 134 lb 5/11/2012 Physician Japan
Primary
Concomitant
Cholecystitis Acute Other Serious 10/4/2011 51 Male 121 lb 5/19/2012 Physician Japan
Primary
Secondary
Concomitant
Gastritis Erosive Hospitalization 2/13/2012 71 Male 134 lb 5/21/2012 Physician Japan
Primary
Concomitant
Cerebrovascular Disorder Hospitalization 5/14/2012 51 Female 5/22/2012 Physician Japan
Primary
Concomitant
Ischaemic Ulcer Hospitalization 3/11/2012 74 Male 150 lb 5/22/2012 Physician Spain
Primary
Secondary
Blood Bilirubin Increased Death 5/10/2012 51 Female 5/30/2012 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Hospitalization 3/17/2012 67 Male 123 lb 6/4/2012 Physician Japan
Primary
Secondary
Concomitant
Anaemia Other Serious 1/23/2012 69 Male 6/5/2012 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 1/1/2011 54 Male 121 lb 6/5/2012 Physician Japan
Primary
Concomitant
Recurrent Cancer Other Serious 6/7/2012 Physician Germany
Primary
Concomitant
Recurrent Cancer Other Serious 6/7/2012 Physician Germany
Primary
Concomitant
Neoplasm Progression Other Serious 6/7/2012 Physician Germany
Primary
Concomitant
Rash Other Serious 61 Male 6/8/2012 Physician Germany
Primary
Concomitant
Recurrent Cancer Other Serious 6/8/2012 Physician Germany
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 4/13/2012 49 Male 126 lb 6/11/2012 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 11/16/2011 65 Female 121 lb 6/20/2012 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Death 10/17/2011 66 Male 108 lb 6/21/2012 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/23/2012 64 Female 6/22/2012 Physician Japan
Primary
Secondary
Concomitant
Infection Hospitalization 6/1/2012 60 Female 6/22/2012 Physician Germany
Primary
Concomitant
Anaemia Hospitalization 6/27/2012 Other Health Professional United States
Primary
Secondary
Deep Vein Thrombosis Other Serious 10/17/2011 63 Male 141 lb 6/28/2012 Physician Japan
Primary
Concomitant
Haemorrhage Hospitalization Male 6/27/2012 Other Health Professional United States
Primary
Secondary
Stomatitis Other Serious 4/9/2012 69 Male 134 lb 6/28/2012 Physician Japan
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 2/21/2012 40 Male 7/2/2012 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Toxicity Other Serious 7/3/2012 Physician United States
Primary
Concomitant
Gastrointestinal Toxicity Other Serious 7/4/2012 Physician United States
Primary
Concomitant
Gastrointestinal Toxicity Other Serious 7/4/2012 Physician United States
Primary
Concomitant
Gastrointestinal Toxicity Other Serious 7/4/2012 Physician United States
Primary
Concomitant
Gastrointestinal Toxicity Other Serious 7/4/2012 Physician United States
Primary
Concomitant
Gastrointestinal Toxicity Other Serious 7/4/2012 Physician United States
Primary
Concomitant
Gastrointestinal Toxicity Other Serious 7/4/2012 Physician United States
Primary
Concomitant
Gastrointestinal Toxicity Other Serious 7/4/2012 Physician United States
Primary
Concomitant
Neoplasm Malignant Hospitalization 1/1/2012 74 Male 7/5/2012 Physician Japan
Primary
Secondary
Concomitant
Constipation Other Serious 9/1/2011 65 Male 7/6/2012 Physician Japan
Primary
Secondary
Concomitant
Cholecystitis Acute Hospitalization 10/4/2011 51 Male 121 lb 7/10/2012 Physician Japan
Primary
Secondary
Concomitant
Pancreatic Pseudocyst Death 6/1/2012 64 Male 7/10/2012 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 12/8/2011 53 Male 7/18/2012 Physician Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Other Serious 5/10/2012 51 Female 7/26/2012 Physician Japan
Primary
Secondary
Concomitant
Blood Bilirubin Increased Hospitalization 10/4/2011 51 Male 121 lb 7/27/2012 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/7/2012 71 Female 123 lb 8/1/2012 Other Health Professional United States
Primary
Secondary
Diarrhoea Other Serious 7/22/2012 63 Female 115 lb 8/1/2012 Physician United States
Primary
Secondary
Platelet Count Decreased Other Serious 1/12/2012 59 Female 8/2/2012 Physician Japan
Primary
Secondary
Concomitant
Bilirubin Conjugated Increased Hospitalization 9/27/2011 62 Female 152 lb 8/2/2012 Other Health Professional United States
Primary
Secondary
Cellulitis Hospitalization 7/19/2012 58 Male 117 lb 8/2/2012 Physician Israel
Primary
Secondary
Concomitant
Rash Other Serious 5/18/2012 68 Male 8/3/2012 Physician Japan
Primary
Secondary
Concomitant
Nausea Other Serious 5/23/2012 61 Female 8/3/2012 Physician Japan
Primary
Secondary
Concomitant
Shock Death 6/14/2012 52 Female 8/6/2012 Physician Japan
Primary
Concomitant
Hyperglycaemia Other Serious 7/18/2010 55 Male 235 lb 8/3/2012 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 7/1/2012 Male 218 lb 8/7/2012 Physician United States
Primary
Secondary
Neoplasm Progression Hospitalization 5/31/2012 57 Male 142 lb 7/26/2012 Other Health Professional United States
Primary
Secondary
Decreased Appetite Other Serious 5/1/2012 75 Male 8/8/2012 Physician Japan
Primary
Concomitant
Nausea Other Serious 4/9/2012 69 Male 134 lb 8/9/2012 Physician Japan
Primary
Secondary
Concomitant
Dermatitis Acneiform Other Serious 4/20/2012 63 Female 8/9/2012 Physician Japan
Primary
Secondary
Concomitant
Hypoalbuminaemia Hospitalization 2/5/2012 63 Male 121 lb 8/9/2012 Physician Japan
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 10/24/2011 72 Male 8/9/2012 Physician Japan
Primary
Secondary
Concomitant
Urticaria Death 12/8/2011 53 Male 8/9/2012 Physician Japan
Primary
Secondary
Concomitant
Incorrect Dose Administered Hospitalization 7/1/2012 67 Female 181 lb 8/10/2012 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 6/1/2012 64 Male 8/10/2012 Physician Japan
Primary
Concomitant
Hospitalisation Hospitalization 3/17/2012 67 Male 123 lb 8/13/2012 Physician Japan
Primary
Secondary
Concomitant
Klebsiella Sepsis Life Threatening 3/29/2012 59 Male 8/13/2012 Physician Australia
Primary
Secondary
Concomitant
Cerebral Infarction Life Threatening 3/21/2012 69 Male 119 lb 8/14/2012 Physician Japan
Primary
Secondary
Ulcerative Keratitis Other Serious 4/4/2012 65 Female 126 lb 8/15/2012 Physician Japan
Primary
Secondary
Concomitant

Drug Data