Eplerenone combined with Lasix

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Paraesthesia Other Serious 1/1/2003 Male 172 lb 3/8/2006 Consumer United States
Primary
Concomitant
Skin Ulcer Other Serious 1/1/2003 Male 172 lb 5/17/2006 Physician United States
Primary
Concomitant
Cardiac Arrest Death 4/28/2007 Female 5/10/2007 Australia
Primary
Concomitant
Bradycardia Other Serious 12/1/2007 70 Female 12/28/2007 Physician Japan
Primary
Secondary
Concomitant
Polyuria Other Serious 12/25/2007 80 Female 1/4/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Bradycardia Other Serious 11/23/2007 Female 86 lb 1/22/2008 Physician Japan
Primary
Secondary
Concomitant
Bradycardia Other Serious 11/23/2007 Female 86 lb 2/5/2008 Physician Japan
Primary
Secondary
Concomitant
Brain Death Hospitalization 1/5/2008 70 Male 2/8/2008 Physician Japan
Primary
Concomitant
Brain Death Hospitalization 1/5/2008 71 Female 2/14/2008 Physician Japan
Primary
Concomitant
Hepatitis Fulminant Life Threatening 3/31/2008 70 Male 4/7/2008 Physician Japan
Primary
Secondary
Platelet Count Decreased Other Serious 3/13/2008 81 Female 4/11/2008 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 3/30/2008 70 Male 4/18/2008 Physician Japan
Primary
Secondary
Platelet Count Decreased Other Serious 3/13/2008 81 Female 4/18/2008 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 3/30/2008 Male 154 lb 4/24/2008 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 4/25/2008 40 Female 5/20/2008 Physician Japan
Primary
Secondary
Concomitant
Jaundice Other Serious 5/14/2008 68 Male 5/28/2008 Physician Japan
Primary
Concomitant
Renal Failure Acute Life Threatening 3/30/2008 Male 154 lb 5/29/2008 Physician Japan
Primary
Secondary
Hepatic Function Abnormal Hospitalization 4/25/2008 Female 85 lb 5/30/2008 Physician Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Inflammation Hospitalization 4/25/2008 Female 85 lb 6/9/2008 Physician Japan
Primary
Secondary
Concomitant
Jaundice Other Serious 5/14/2008 Male 144 lb 6/30/2008 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 5/14/2008 68 7/8/2008 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 5/14/2008 68 Male 7/10/2008 Physician Japan
Primary
Secondary
Concomitant
Jaundice Other Serious 5/14/2008 Male 144 lb 7/15/2008 Physician Japan
Primary
Secondary
Concomitant
Conjunctivitis Other Serious 8/21/2008 Male 108 lb 11/18/2008 Physician Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 11/26/2008 Male 173 lb 1/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/29/2007 3/10/2009 Physician France
Primary
Secondary
Concomitant
Localised Infection Hospitalization 2/4/2009 3/23/2009 Physician France
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/23/2009 Male 5/1/2009 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Hospitalization 4/30/2009 Male 179 lb 5/11/2009 United States
Primary
Concomitant
Pneumonia Aspiration Other Serious 7/9/2008 Female 6/2/2009 Physician Japan
Primary
Concomitant
Pneumonia Aspiration Other Serious 7/9/2008 Female 6/5/2009 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 5/1/2009 Male 148 lb 6/24/2009 Physician Japan
Primary
Secondary
Concomitant
Death Death 6/9/2009 79 7/3/2009 Other Health Professional Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 5/1/2009 Male 148 lb 7/5/2009 Physician Japan
Primary
Secondary
Concomitant
Urinary Retention Other Serious 6/10/2009 54 7/13/2009 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 3/23/2009 Male 130 lb 7/15/2009 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 5/1/2009 Male 148 lb 7/20/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 3/23/2009 Male 130 lb 7/23/2009 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 3/23/2009 Male 130 lb 8/24/2009 Physician Japan
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Death Death 79 Male 10/13/2009 Other Health Professional Japan
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 51 Male 10/20/2009 United States
Primary
Concomitant
Surgery Hospitalization 9/28/2009 Male 175 lb 11/17/2009 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 51 Male 11/11/2009 United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 51 Male 11/24/2009 United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 51 Male 12/1/2009 Lawyer United States
Primary
Concomitant
Chest Pain Life Threatening 4/20/2009 Female 128 lb 12/22/2009 Physician Japan
Primary
Concomitant
Musculoskeletal Stiffness Hospitalization 9/4/2009 73 Male 1/14/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 51 Male 1/13/2010 United States
Primary
Concomitant
Renal Impairment Hospitalization 9/23/2009 83 Male 132 lb 1/29/2010 Physician Japan
Primary
Secondary
Concomitant
Chest Pain Life Threatening 4/20/2009 Female 128 lb 2/3/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 1/30/2010 Male 126 lb 3/1/2010 Physician Japan
Primary
Concomitant
Sepsis Other Serious 1/19/2008 65 Male 2/5/2010 United States
Primary
Concomitant
Renal Impairment Other Serious 1/30/2010 Male 126 lb 3/22/2010 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 12/25/2009 64 Male 150 lb 3/23/2010 Physician Greece
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 9/23/2009 83 Male 132 lb 3/31/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/29/2010 69 Male 126 lb 4/1/2010 Pharmacist Japan
Primary
Concomitant
Melaena Required Intervention 12/7/2009 57 Male 168 lb 12/11/2009 Pharmacist United States
Primary
Concomitant
Gynaecomastia Other Serious 4/7/2010 80 Male 4/28/2010 Japan
Primary
Concomitant
Gynaecomastia 4/7/2010 80 Male 5/6/2010 Japan
Primary
Concomitant
Renal Failure Hospitalization 5/26/2010 -1 Male 154 lb 6/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/26/2010 70 Male 154 lb 7/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 9/23/2009 83 Male 132 lb 7/21/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Hospitalization 5/26/2010 70 Male 154 lb 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 11/26/2008 86 Male 172 lb 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11/16/2009 59 Female 185 lb 8/10/2010 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 51 Male 8/4/2010 United States
Primary
Concomitant
Renal Impairment Hospitalization 1/26/2010 72 Male 137 lb 8/23/2010 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/12/2010 87 Male 178 lb 9/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/12/2010 87 Male 179 lb 9/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 9/23/2009 83 Male 132 lb 10/22/2010 Physician Japan
Primary
Secondary
Concomitant
Inguinal Hernia Hospitalization 5/12/2008 84 Male 187 lb 11/26/2010 Physician Italy
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/1/2008 69 Male 12/1/2010 Other Health Professional Japan
Primary
Concomitant
Cardiac Failure Hospitalization 10/23/2010 77 Male 176 lb 12/13/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 1/28/2011 78 Male 132 lb 2/9/2011 Physician Japan
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Hospitalization 1/28/2011 78 Male 132 lb 2/18/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/28/2011 78 Male 132 lb 3/3/2011 Physician Japan
Primary
Secondary
Concomitant
Asthenia Other Serious 1/28/2011 78 Male 132 lb 3/14/2011 Physician Japan
Primary
Secondary
Concomitant
Angina Pectoris Hospitalization 1/6/2011 76 Male 117 lb 3/21/2011 Physician Japan
Primary
Secondary
Tremor 2/24/2011 79 Male 3/23/2011 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/28/2011 78 Male 132 lb 3/25/2011 Physician Japan
Primary
Secondary
Concomitant
Hypophosphataemia Disability 6/15/2009 75 Male 3/30/2011 Physician Japan
Primary
Concomitant
Angina Pectoris Hospitalization 1/6/2011 76 Male 117 lb 3/31/2011 Consumer United States
Primary
Secondary
Angina Pectoris Hospitalization 1/6/2011 76 Male 117 lb 4/1/2011 Physician Japan
Primary
Secondary
Dehydration Hospitalization 1/28/2011 78 Male 132 lb 4/5/2011 Physician Japan
Primary
Secondary
Concomitant
Asthenia Hospitalization 2/28/2011 71 Male 194 lb 3/28/2011 Physician United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 3/15/2011 71 Male 185 lb 3/29/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Asthenia Hospitalization 2/28/2011 71 Male 194 lb 4/6/2011 Physician United States
Primary
Secondary
Concomitant
Cholangitis Other Serious 1/28/2011 78 Male 132 lb 4/18/2011 Physician Japan
Primary
Secondary
Concomitant
Thyroiditis Hospitalization 3/15/2011 71 Male 185 lb 4/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cells Urine Positive Hospitalization 3/15/2011 71 Male 185 lb 4/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Asthenia Hospitalization 1/28/2011 78 Male 132 lb 5/9/2011 Physician Japan
Primary
Secondary
Concomitant
Jaundice Hospitalization 3/15/2011 71 Male 185 lb 4/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Mallory-weiss Syndrome Hospitalization 4/16/2011 73 Female 5/27/2011 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 4/21/2011 73 Female 133 lb 6/3/2011 Physician Japan
Primary
Concomitant
Haemoptysis Hospitalization 4/16/2011 57 Male 154 lb 6/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemoptysis Hospitalization 4/16/2011 57 Male 154 lb 6/2/2011 Consumer United States
Primary
Secondary
Concomitant
Hypotension Other Serious 5/12/2011 72 Male 6/13/2011 Physician Portugal
Primary
Concomitant
Hypotension Other Serious 4/28/2011 72 Male 6/21/2011 Physician Portugal
Primary
Concomitant
Bronchial Disorder Hospitalization 3/20/2007 80 Male 181 lb 6/23/2011 Physician France
Primary
Concomitant
Renal Failure Hospitalization 10/29/2007 71 Female 134 lb 6/23/2011 Physician France
Primary
Concomitant
Ventricular Tachycardia Hospitalization 12/25/2008 59 Male 190 lb 6/24/2011 Physician United States
Primary
Concomitant
Bradycardia Other Serious 4/27/2011 73 Male 187 lb 6/24/2011 Physician United States
Primary
Secondary
Concomitant
Pulmonary Congestion Hospitalization 6/11/2011 69 Male 163 lb 6/27/2011 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 5/26/2010 70 Male 154 lb 6/28/2011 Other Health Professional United States
Primary
Concomitant
Medication Residue 6/16/2011 73 Male 6/30/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 4/27/2011 73 Male 187 lb 6/30/2011 Physician United States
Primary
Secondary
Concomitant
Gouty Arthritis Hospitalization 1/27/2009 71 Male 137 lb 7/5/2011 Consumer Korea, Republic Of
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 7/6/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Other Serious 4/28/2011 72 Male 7/11/2011 Physician Portugal
Primary
Concomitant
Asthenia Hospitalization 1/28/2011 78 Male 132 lb 6/24/2011 Physician Japan
Primary
Secondary
Concomitant
Fluid Overload Hospitalization 6/11/2011 69 Male 163 lb 7/19/2011 Physician Japan
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/28/2011 78 Male 132 lb 7/27/2011 Physician Japan
Primary
Secondary
Concomitant
Emotional Disorder Hospitalization 4/24/2006 62 Male 186 lb 7/27/2011 Consumer United States
Primary
Concomitant
Renal Impairment Death 5/23/2007 64 Male 186 lb 8/3/2011 Lawyer United States
Primary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 8/10/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebellar Haemorrhage Hospitalization 6/18/2011 61 Male 128 lb 8/11/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebellar Haemorrhage Hospitalization 6/18/2011 61 Male 128 lb 8/24/2011 Physician Japan
Primary
Secondary
Concomitant
Syncope Other Serious 6/24/2011 64 Male 190 lb 8/25/2011 Other Health Professional United States
Primary
Concomitant
Hypoglycaemia Other Serious 6/24/2011 64 Male 190 lb 9/1/2011 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/20/2011 79 Male 134 lb 9/2/2011 Physician Japan
Primary
Secondary
Concomitant
Bacterial Test Positive Hospitalization 8/20/2011 79 Male 134 lb 9/13/2011 Physician Japan
Primary
Secondary
Concomitant
Conjunctival Hyperaemia Other Serious 8/12/2011 79 Male 9/16/2011 Physician Japan
Primary
Concomitant
Asthenia Hospitalization 3/15/2011 71 Male 185 lb 9/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 9/28/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/20/2011 79 Male 134 lb 9/30/2011 Physician Japan
Primary
Secondary
Concomitant
Conjunctival Hyperaemia Other Serious 8/4/2011 79 Male 141 lb 10/4/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 10/6/2011 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/20/2011 79 Male 134 lb 10/12/2011 Physician Japan
Primary
Secondary
Concomitant
Hypotension Other Serious 4/28/2011 72 Male 10/13/2011 Physician Portugal
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 9/1/2011 77 Male 10/13/2011 Consumer United States
Primary
Concomitant
Conjunctival Hyperaemia Other Serious 8/4/2011 79 Male 141 lb 10/19/2011 Physician Japan
Primary
Concomitant
Mental Status Changes Hospitalization 4/27/2011 73 Male 187 lb 10/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious 4/27/2011 73 Male 187 lb 10/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Polyp Hospitalization 73 Female 337 lb 11/2/2011 Physician France
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/20/2011 79 Male 134 lb 11/2/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 4/27/2011 73 Male 187 lb 11/14/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 6/11/2011 69 Male 163 lb 11/18/2011 Physician Japan
Primary
Secondary
Concomitant
Iron Deficiency Anaemia Hospitalization 75 Female 337 lb 11/21/2011 Physician France
Primary
Concomitant
Chest Discomfort Hospitalization 8/22/2011 62 Male 196 lb 11/22/2011 Pharmacist United States
Primary
Concomitant
Acute Pulmonary Oedema Hospitalization 11/3/2011 66 Male 11/23/2011 Physician Portugal
Primary
Concomitant
Blood Creatinine Increased Life Threatening 10/29/2011 54 Male 154 lb 11/22/2011 Physician Japan
Primary
Concomitant
Bradycardia Other Serious 4/27/2011 73 Male 187 lb 12/2/2011 Physician United States
Primary
Secondary
Concomitant
Altered State Of Consciousness Hospitalization 3/19/2009 79 Male 130 lb 12/5/2011 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 11/17/2011 78 Male 12/6/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 10/29/2011 54 Male 154 lb 12/1/2011 Physician Japan
Primary
Concomitant
Pulmonary Congestion Hospitalization 6/11/2011 69 Male 163 lb 12/12/2011 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 11/17/2011 78 Male 12/19/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Gait Disturbance Disability 6/15/2009 75 Male 12/20/2011 Physician Japan
Primary
Concomitant
Pulmonary Congestion Hospitalization 6/11/2011 69 Male 163 lb 12/26/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data