Epirubicin combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Osteonecrosis Other Serious 11/9/2005 65 Female 95 lb 4/7/2006 Physician Germany
Primary
Concomitant
Visual Acuity Reduced Disability 12/1/2005 58 Female 5/3/2006 Physician Spain
Primary
Concomitant
Paraesthesia Disability 2/1/2006 56 Female 5/4/2006 Physician Spain
Primary
Secondary
Concomitant
Swelling Other Serious 12/1/2004 64 Female 143 lb 5/23/2006 Physician Hungary
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/1/2005 65 Female 115 lb 5/23/2006 Physician Hungary
Primary
Secondary
Concomitant
Swelling Other Serious 4/13/2006 51 Female 5/24/2006 Physician Portugal
Primary
Concomitant
Paraesthesia Disability 3/1/2006 56 Female 5/22/2006 Physician Spain
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2003 60 Female 6/2/2006 Physician Germany
Primary
Secondary
Concomitant
Paraesthesia Disability 3/1/2006 56 Female 6/2/2006 Physician Spain
Primary
Secondary
Concomitant
Stomatitis Other Serious 5/1/2004 54 Female 154 lb 6/22/2006 Physician Germany
Primary
Concomitant
Visual Acuity Reduced Disability 6/1/2005 57 Female 7/11/2006 Physician Spain
Primary
Concomitant
Paraesthesia Disability 3/1/2006 56 Female 7/13/2006 Physician Spain
Primary
Concomitant
Osteomyelitis Hospitalization 7/21/2005 46 Female 7/24/2006 Italy
Primary
Concomitant
Prosthesis Implantation Other Serious 1/17/2006 61 Female 9/18/2006 Physician Belgium
Primary
Concomitant
Osteonecrosis Other Serious 2/1/2006 50 Female 9/18/2006 Physician Belgium
Primary
Concomitant
Soft Tissue Infection Disability 7/1/2006 49 Female 9/21/2006 Physician Australia
Primary
Concomitant
Neutrophil Count Decreased Death 8/21/2006 64 Female 125 lb 10/4/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neutrophil Count Decreased Hospitalization 8/21/2006 64 Female 10/13/2006 Consumer United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2005 64 Female 84 lb 12/12/2006 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2005 64 Female 84 lb 12/14/2006 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2005 64 Female 84 lb 12/22/2006 Physician Japan
Primary
Secondary
Concomitant
Muscle Spasms Hospitalization 9/1/2006 70 Female 1/22/2007 Physician Belgium
Primary
Concomitant
Muscle Spasms Hospitalization 12/18/2006 70 Female 2/7/2007 Physician Belgium
Primary
Concomitant
X-ray Abnormal Disability 6/1/2005 56 Female 4/17/2007 France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 4/1/2007 43 Female 6/12/2007 Physician Austria
Primary
Concomitant
Tooth Extraction Other Serious 3/23/2004 53 Female 8/18/2007 Physician Belgium
Primary
Concomitant
Tooth Extraction Other Serious 3/23/2004 53 Female 8/18/2007 Physician Belgium
Primary
Concomitant
Stomatitis Other Serious 9/12/2000 60 Female 9/19/2007 France
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/12/2000 60 Female 10/6/2007 France
Primary
Secondary
Concomitant
Metrorrhagia 7/27/2007 68 Female 10/31/2007 Other Health Professional Italy
Primary
Concomitant
X-ray Abnormal Other Serious 10/7/2002 61 Female 11/1/2007 Physician
Primary
Concomitant
Impaired Healing Hospitalization 8/10/2007 50 Female 128 lb 11/29/2007 Physician Germany
Primary
Secondary
Concomitant
Pain In Jaw Hospitalization 1/10/2007 68 Female 12/12/2007 France
Primary
Concomitant
Osteonecrosis Other Serious 10/26/2007 60 Female 137 lb 12/22/2007 Other Health Professional Denmark
Primary
Concomitant
Spondylitis Other Serious 31 Female 1/25/2008 Consumer United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/26/2007 60 Female 137 lb 1/29/2008 Other Health Professional Denmark
Primary
Concomitant
Spondylitis Other Serious 31 Female 1/31/2008 Consumer United States
Primary
Secondary
Concomitant
Spondylitis Other Serious 31 Female 2/7/2008 Consumer United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 7/5/2007 60 Female 165 lb 3/11/2008 Denmark
Primary
Concomitant
Osteonecrosis Other Serious 6/9/2007 66 Female 126 lb 3/17/2008 Physician Denmark
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/9/2007 66 Female 126 lb 3/18/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 12/12/2000 42 Female 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/1/2007 Female 4/24/2008 Physician Germany
Primary
Concomitant
Swelling Other Serious 12/1/2007 61 Female 5/14/2008 Physician Australia
Primary
Secondary
Concomitant
Swelling Other Serious 6/9/2007 Female 126 lb 5/20/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 10/7/2002 61 Female 5/22/2008 Physician Germany
Primary
Concomitant
Swelling Other Serious 6/9/2007 Female 126 lb 5/29/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/9/2007 Female 126 lb 7/31/2008 Physician Denmark
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious 4/1/2002 8/20/2008 United States
Primary
Secondary
Concomitant
Swelling Other Serious 6/9/2007 Female 126 lb 8/22/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 5/1/2008 Female 9/17/2008 Physician Germany
Primary
Secondary
Toothache Other Serious 3/1/2008 Female 11/11/2008 Other Health Professional United States
Primary
Concomitant
X-ray Abnormal Other Serious 10/7/2002 Female 1/23/2009 Physician Germany
Primary
Concomitant
Tooth Extraction Hospitalization 9/1/2008 Female 2/23/2009 Consumer Germany
Primary
Concomitant
X-ray Abnormal Other Serious 10/7/2002 Female 3/10/2009 Physician Germany
Primary
Concomitant
Osteonecrosis Other Serious 11/28/2008 Female 152 lb 3/23/2009 Physician Germany
Primary
Concomitant
Temporal Arteritis Hospitalization 3/1/2009 Female 5/7/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 11/1/2007 76 Female 7/10/2009 Other Health Professional Japan
Primary
Concomitant
Tooth Extraction Hospitalization 9/1/2008 Female 7/16/2009 Physician Germany
Primary
Concomitant
Tooth Extraction Other Serious 4/21/2004 Female 150 lb 12/11/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 4/21/2004 Female 150 lb 12/28/2009 Physician United States
Primary
Secondary
Concomitant
Sequestrectomy Other Serious 9/1/2003 Female 12/29/2009 Other Health Professional Italy
Primary
Concomitant
Sensory Disturbance Other Serious 6/29/2007 Female 126 lb 1/4/2010 Denmark
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 12/1/2009 Female 140 lb 1/15/2010 Physician Germany
Primary
Secondary
Concomitant
Sequestrectomy Other Serious 9/1/2003 Female 1/29/2010 Other Health Professional Italy
Primary
Concomitant
Peptostreptococcus Infection Other Serious 9/1/2009 Female 2/8/2010 Other Health Professional Denmark
Primary
Concomitant
Wound Infection Other Serious 5/16/2007 Female 2/15/2010 United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 5/16/2007 Female 200 lb 3/4/2010 United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 5/16/2007 Female 200 lb 3/17/2010 United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 5/16/2007 Female 200 lb 3/26/2010 United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 1/1/2006 44 Female 200 lb 4/20/2010 United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 1/1/2006 44 Female 200 lb 6/7/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2005 78 Female 6/25/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2005 78 Female 7/9/2010 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 7/30/2010 57 Male 8/18/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2002 50 Female 168 lb 8/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2002 50 Female 168 lb 8/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2002 50 Female 168 lb 9/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 4/1/2002 50 Female 168 lb 9/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 7/30/2010 57 Male 9/23/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2005 78 Female 9/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2002 50 Female 168 lb 9/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 4/21/2004 38 Female 150 lb 9/30/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2005 78 Female 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2005 78 Female 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2002 50 Female 168 lb 10/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 4/21/2004 38 Female 150 lb 10/8/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/1/2002 50 Female 168 lb 10/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toothache Other Serious 4/16/2009 50 Female 130 lb 11/8/2010 Pharmacist Japan
Primary
Concomitant
Toothache Other Serious 4/16/2009 50 Female 130 lb 11/27/2010 Pharmacist Japan
Primary
Concomitant
Weight Decreased Other Serious 3/26/2004 52 Female 168 lb 12/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/26/2004 52 Female 168 lb 12/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Toothache Other Serious 4/16/2009 50 Female 130 lb 12/13/2010 Pharmacist Japan
Primary
Concomitant
Weight Decreased Other Serious 3/26/2004 52 Female 168 lb 12/20/2010 United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Disability 1/1/2010 Female 1/28/2011 Physician Malta
Primary
Concomitant
Haematocrit Decreased Death 1/1/2009 64 Female 143 lb 1/28/2011 Physician Japan
Primary
Concomitant
Osteonecrosis Of Jaw Disability Female 2/4/2011 Physician Malta
Primary
Concomitant
Death Death 1/24/2009 68 Female 126 lb 2/4/2011 Denmark
Primary
Secondary
Concomitant
Aphagia Disability 12/27/2010 Female 2/7/2011 Physician Malta
Primary
Secondary
Concomitant
Toothache Other Serious 47 Female 2/7/2011 Other Health Professional Japan
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 9/1/2009 47 Female 2/10/2011 Other Health Professional Denmark
Primary
Concomitant
Osteonecrosis Other Serious 6/9/2007 66 Female 126 lb 2/18/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Abscess Death 1/24/2009 68 Female 126 lb 2/25/2011 Physician Denmark
Primary
Secondary
Concomitant
Blood Urea Increased Other Serious 1/14/2009 64 Female 143 lb 3/15/2011 Physician Japan
Primary
Concomitant
Fungal Infection Other Serious 4/21/2004 38 Female 150 lb 4/5/2011 Lawyer United States
Primary
Secondary
Concomitant
Gingival Erythema Other Serious 1/14/2009 64 Female 143 lb 5/25/2011 Physician Japan
Primary
Concomitant
Portal Hypertension Other Serious 3/25/2009 67 Female 128 lb 6/4/2011 Physician Germany
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 60 Female 7/1/2011 Physician Japan
Primary
Secondary
Concomitant
Fibrocystic Breast Disease Other Serious 12/12/2000 47 Female 7/1/2011 Lawyer United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 60 Female 7/26/2011 Physician Japan
Primary
Secondary
Concomitant
Phlebolith Other Serious 12/12/2000 47 Female 7/27/2011 Physician United States
Primary
Secondary
Concomitant
Immune System Disorder Other Serious 4/21/2004 38 Female 150 lb 7/28/2011 Physician United States
Primary
Secondary
Concomitant
Osteomyelitis Hospitalization 1/1/2003 48 Female 194 lb 8/3/2011 Lawyer United States
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 12/12/2000 47 Female 8/26/2011 Physician United States
Primary
Secondary
Concomitant
Stress Fracture Hospitalization 1/1/2003 48 Female 194 lb 9/2/2011 Lawyer United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Death 9/1/2003 57 Female 9/12/2011 Other Health Professional Italy
Primary
Concomitant
Depressed Level Of Consciousness Hospitalization 1/1/2003 48 Female 194 lb 10/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious Female 12/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 12/12/2000 47 Female 12/27/2011 Physician United States
Primary
Secondary
Concomitant
Bone Lesion Other Serious 9/1/2007 72 Female 95 lb 2/6/2012 Physician France
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 12/12/2000 47 Female 2/16/2012 Consumer United States
Primary
Secondary
Concomitant
Abscess Other Serious 4/21/2004 38 Female 150 lb 2/20/2012 Physician United States
Primary
Secondary
Concomitant
Decubitus Ulcer Hospitalization 12/12/2000 47 Female 3/6/2012 Physician United States
Primary
Secondary
Concomitant
Impaired Gastric Emptying Other Serious Female 3/7/2012 Lawyer United States
Primary
Secondary
Concomitant
Abscess Jaw Other Serious 65 Female 3/13/2012 Physician Belgium
Primary
Secondary
Concomitant
Oral Disorder Other Serious 12/12/2000 47 Female 3/27/2012 Physician United States
Primary
Secondary
Concomitant
Constipation Other Serious 11/23/2007 65 Female 4/6/2012 Lawyer United States
Primary
Secondary
Concomitant
Oral Disorder Other Serious 12/12/2000 47 Female 4/24/2012 Physician United States
Primary
Secondary
Concomitant
Headache Other Serious 11/23/2007 65 Female 4/25/2012 Consumer United States
Primary
Secondary
Concomitant
Ear Pain Other Serious 11/23/2007 65 Female 5/4/2012 Lawyer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/12/2000 47 Female 6/25/2012 Consumer United States
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Other Serious 5/21/2012 60 Female 154 lb 7/11/2012 Physician United States
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 5/26/2012 69 Female 7/17/2012 Other Health Professional Italy
Primary
Concomitant
Neuralgia Death 11/23/2007 65 Female 8/1/2012 Consumer United States
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 5/26/2012 69 Female 8/2/2012 Other Health Professional Italy
Primary
Concomitant
Pathological Fracture Hospitalization 1/1/2003 48 Female 194 lb 8/8/2012 Physician United States
Primary
Secondary
Concomitant
Bursitis Death 11/23/2007 65 Female 8/10/2012 Consumer United States
Primary
Secondary
Concomitant
Wound Dehiscence Death 6/1/2005 56 Female 176 lb 12/29/2012 Other Health Professional Dk
Primary
Concomitant
Weight Gain Poor Other Serious 63 Male 9/21/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Wound Other Serious Female 9/27/2012 Physician Us
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 2/2/2012 67 Female 6/25/2013 Other Health Professional Dk
Primary
Concomitant
Pleural Effusion Other Serious 9/22/2012 45 Female 158 lb 6/4/2013 Consumer Us
Primary
Concomitant
Metastases To The Mediastinum Other Serious 7/29/2009 Female 1/31/2013 Physician Dk
Primary
Secondary
Metastases To The Mediastinum Other Serious 7/29/2009 35 Female 137 lb 2/28/2013 Other Health Professional Dk
Primary
Secondary
Metastases To The Mediastinum Other Serious 7/29/2009 35 Female 2/11/2013 Physician Dk
Primary
Secondary
Metastases To The Mediastinum Other Serious 7/29/2009 35 Female 137 lb 2/26/2013 Physician Dk
Primary
Secondary
Disease Progression Other Serious 11/2012 50 Female 3/25/2013 Physician Tw
Primary
Secondary
Concomitant
Wound Secretion Other Serious 4/21/2004 39 Female 150 lb 3/14/2013 Consumer Us
Primary
Secondary
Concomitant
Weight Decreased Death 3/26/2004 52 Female 168 lb 8/1/2013 Consumer Us
Primary
Secondary
Concomitant
Vomiting Other Serious 12/12/2000 47 Female 8/30/2013 Consumer Us
Primary
Secondary
Concomitant

Drug Data