Epirubicin Hydrochloride combined with Fluorouracil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Hospitalization 53 Female 176 lb 1/12/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/28/2005 45 Female 139 lb 2/24/2006 United States
Primary
Concomitant
Therapy Non-responder Hospitalization 1/21/2005 Female 149 lb 6/6/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious 10/10/2006 48 Female 141 lb 11/14/2006 Physician Germany
Primary
Secondary
Concomitant
Convulsion Other Serious 10/10/2006 48 Female 141 lb 11/27/2006 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Death 9/18/2006 44 Female 11/21/2006 Hong Kong
Primary
Secondary
Concomitant
Petechiae Other Serious 60 Female 12/4/2006 Physician France
Primary
Secondary
Pancreatitis Acute Other Serious 11/25/2006 60 Female 12/18/2006 Physician Japan
Primary
Secondary
Petechiae 11/10/2006 Female 172 lb 12/29/2006 Physician France
Primary
Secondary
Vasculitis Other Serious 10/10/2006 Female 12/29/2006 Pharmacist Japan
Primary
Concomitant
Somnolence Death 9/18/2006 44 Female 12/27/2006 Hong Kong
Primary
Secondary
Concomitant
Urinary Retention Other Serious 11/23/2006 36 Female 161 lb 1/23/2007 Other Health Professional France
Primary
Concomitant
Neutropenia Hospitalization 8/21/2006 Female 2/2/2007 Australia
Primary
Secondary
Delirium Other Serious 1/17/2007 Female 2/7/2007 Physician Australia
Primary
Secondary
Neuralgia Hospitalization 11/28/2006 41 Female 2/9/2007 Other Health Professional France
Primary
Secondary
Neutropenia Hospitalization 1/21/2005 Female 149 lb 2/27/2007 Physician United States
Primary
Concomitant
Tinnitus Other Serious 48 Female 2/28/2007 Pharmacist Norway
Primary
Secondary
Cardiac Arrest Life Threatening 1/31/2007 73 Female 198 lb 3/21/2007
Primary
Concomitant
Sepsis Death 9/18/2006 44 Female 3/9/2007 Hong Kong
Primary
Secondary
Concomitant
Febrile Neutropenia 1/3/2006 Female 3/28/2007 Other Health Professional United States
Primary
Concomitant
Shock Life Threatening Female 3/30/2007 Physician France
Primary
Concomitant
Obliterative Bronchiolitis Other Serious 10/16/2006 41 Female 4/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 9/25/2002 66 Female 5/21/2007 Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 9/25/2002 66 Female 5/25/2007 Japan
Primary
Secondary
Concomitant
Urinary Retention Other Serious 11/23/2006 36 Female 161 lb 5/31/2007 Other Health Professional France
Primary
Concomitant
Dyspnoea Other Serious 2/12/2007 Female 170 lb 6/26/2007 United Kingdom
Primary
Secondary
Neoplasm Malignant Hospitalization 4/1/2000 Female 8/17/2007 Other Health Professional France
Primary
Secondary
Sepsis Hospitalization 7/25/2007 Female 97 lb 8/21/2007 Physician Japan
Primary
Secondary
Sepsis Death 7/3/2007 Female 9/25/2007 Physician Greece
Primary
Secondary
Concomitant
Syncope Hospitalization 8/26/2003 Female 140 lb 10/3/2007 Sweden
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 4/24/2006 Female 11/15/2007 France
Primary
Secondary
Platelet Count Decreased Other Serious 1/1/2007 Female 11/20/2007 Physician Japan
Primary
Secondary
Tuberculosis Hospitalization 5/1/2007 Female 11/20/2007 Physician Switzerland
Primary
Secondary
Peliosis Hepatis Life Threatening 1/1/2001 Female 1/23/2008 Other Health Professional France
Primary
Secondary
Arterial Spasm Other Serious Female 3/10/2008 Japan
Primary
Concomitant
Arterial Spasm Other Serious Female 3/10/2008 Japan
Primary
Concomitant
Arterial Spasm Other Serious Female 3/10/2008 Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 6/28/2005 Female 139 lb 3/28/2008 Physician United States
Primary
Concomitant
Nausea Other Serious 11/25/2005 31 Female 5/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Neoplasm Malignant Death 3/14/2005 Female 130 lb 6/26/2008 Physician Sweden
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 65 Female 6/27/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 1/1/2008 65 Female 7/18/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 65 Female 7/16/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 6/3/2008 Female 7/24/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 65 Female 7/23/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 3/14/2005 Female 130 lb 8/7/2008 Physician Sweden
Primary
Secondary
Sickle Cell Anaemia With Crisis Hospitalization 55 Female 8/8/2008 United States
Primary
Secondary
Toxic Shock Syndrome Staphylococcal Hospitalization 52 Female 8/22/2008 Other Health Professional France
Primary
Secondary
Concomitant
Rash Life Threatening 1/1/2007 51 Female 139 lb 8/25/2008 Pharmacist Canada
Primary
Concomitant
Leukopenia Other Serious 12/4/2007 38 Female 8/28/2008 Japan
Primary
Secondary
Concomitant
Nasal Congestion Hospitalization 7/7/2008 Female 8/28/2008 Other Health Professional France
Primary
Concomitant
Weight Increased Other Serious Female 8/29/2008 Consumer France
Primary
Concomitant
Pancytopenia Other Serious 5/21/2008 38 Female 9/3/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pancreatitis Hospitalization Female 9/10/2008 Physician United States
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Other Serious 6/3/2008 Female 9/15/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Influenza Like Illness Hospitalization 5/2/2007 Female 9/25/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 5/1/2008 61 Female 10/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Flank Pain Hospitalization 1/1/2008 43 Female 134 lb 10/29/2008 Other Health Professional Australia
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 5/1/2008 61 Female 10/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Muscle Spasms Other Serious 57 Female 174 lb 11/3/2008 Pharmacist Canada
Primary
Concomitant
Sudden Death Death 10/11/2008 64 Female 260 lb 11/3/2008 United States
Primary
Secondary
Pancreatitis Hospitalization Female 11/7/2008 Physician United States
Primary
Secondary
Sudden Death Death 10/11/2008 64 Female 260 lb 11/10/2008 United States
Primary
Secondary
Neutropenia Hospitalization 10/1/2008 Female 154 lb 11/26/2008 Pharmacist Spain
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 5/1/2008 61 Female 11/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Interstitial Lung Disease Other Serious 56 Female 11/28/2008 Japan
Primary
Secondary
Interstitial Lung Disease Other Serious 62 Female 11/28/2008 Japan
Primary
Secondary
Interstitial Lung Disease Other Serious 63 Female 11/28/2008 Japan
Primary
Secondary
Pancreatitis Hospitalization Female 12/1/2008 Physician United States
Primary
Secondary
Flank Pain Hospitalization 1/1/2008 43 Female 134 lb 12/2/2008 Other Health Professional Australia
Primary
Concomitant
Flank Pain Hospitalization 2/11/2008 43 Female 134 lb 12/2/2008 Physician Australia
Primary
Concomitant
Pyrexia Hospitalization 11/21/2008 80 Female 1/19/2009 Other Health Professional Spain
Primary
Interacting
Interstitial Lung Disease Other Serious 1/23/2009 Physician Japan
Primary
Secondary
Concomitant
Neuralgia Disability 5/1/2008 48 Female 3/16/2009 Other Health Professional France
Primary
Secondary
Concomitant
Phlebitis Hospitalization 7/10/2006 42 Female 168 lb 6/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Periodontal Disease Other Serious 6/1/2008 47 Female 6/18/2009 Other Health Professional Switzerland
Primary
Secondary
Periodontal Disease Other Serious 6/1/2008 42 Female 6/19/2009 Other Health Professional Switzerland
Primary
Secondary
Febrile Neutropenia Hospitalization 4/24/2009 Female 165 lb 7/2/2009 Physician Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 6/26/2009 44 7/23/2009 Other Health Professional Hong Kong
Primary
Secondary
Osteonecrosis Other Serious 7/13/2009 Female 130 lb 8/27/2009 Physician Japan
Primary
Concomitant
Osteonecrosis Other Serious 7/13/2009 Female 130 lb 9/29/2009 Physician Japan
Primary
Concomitant
Cytolytic Hepatitis Hospitalization 7/29/2009 62 Female 10/12/2009 Other Health Professional France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 7/13/2009 Female 130 lb 10/15/2009 Physician Japan
Primary
Concomitant
Congestive Cardiomyopathy Other Serious 7/25/2008 55 Female 10/29/2009 Other Health Professional France
Primary
Secondary
Sequestrectomy Other Serious 7/13/2009 Female 130 lb 11/18/2009 Physician Japan
Primary
Concomitant
Neutropenia Hospitalization 10/1/2008 Female 154 lb 11/19/2009 Pharmacist Spain
Primary
Concomitant
Congestive Cardiomyopathy Other Serious 7/25/2008 55 Female 11/30/2009 Other Health Professional France
Primary
Secondary
Osteonecrosis Disability 1/1/2005 Female 12/2/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Shock Hospitalization 9/15/2009 70 Female 12/7/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Neonatal Respiratory Distress Syndrome Other Serious 1/1/2009 Female 4 lb 12/17/2009 Other Health Professional Switzerland
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 1/6/2009 34 Female 141 lb 12/17/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 61 Female 12/16/2009 Physician Japan
Primary
Secondary
Ejection Fraction Decreased Other Serious 9/15/2009 59 Female 12/21/2009 Other Health Professional France
Primary
Secondary
Neonatal Respiratory Distress Syndrome Other Serious 2/1/2009 Female 5 lb 12/29/2009 Physician Switzerland
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death Female 12/31/2009 Physician United States
Primary
Secondary
Tachycardia Life Threatening 26 Female 146 lb 1/4/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death Female 1/4/2010 Physician United States
Primary
Secondary
Malignant Neoplasm Progression Hospitalization 8/9/2007 Male 1/7/2010 Physician United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 26 Female 146 lb 1/8/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Tachycardia Life Threatening 26 Female 146 lb 1/14/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Tachycardia Hospitalization 4/2/2009 29 Female 1/14/2010 Physician United Kingdom
Primary
Secondary
Supraventricular Tachycardia Other Serious 11/12/2009 50 Female 1/20/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 8/9/2007 Male 1/26/2010 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 4/2/2009 29 Female 1/20/2010 Physician United Kingdom
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 4/1/2008 Female 190 lb 1/27/2010 Physician France
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 6/3/2008 65 Female 1/28/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 2/23/2009 46 Female 2/2/2010 Other Health Professional France
Primary
Secondary
Acute Myeloid Leukaemia Life Threatening 1/1/2006 Female 190 lb 2/16/2010 Physician France
Primary
Secondary
Concomitant
Congestive Cardiomyopathy Other Serious Female 2/18/2010 Other Health Professional France
Primary
Secondary
Concomitant
T-cell Prolymphocytic Leukaemia Other Serious 45 Female 2/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Supraventricular Tachycardia Other Serious 11/12/2009 50 Female 2/22/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 2/5/2010 Female 168 lb 2/22/2010 Physician Germany
Primary
Secondary
Pain In Extremity Other Serious 12/9/2009 74 Female 2/26/2010 Pharmacist Spain
Primary
Concomitant
Skin Depigmentation Other Serious 12/15/2009 64 Female 2/26/2010 Pharmacist Spain
Primary
Concomitant
Skin Depigmentation Other Serious 1/1/2009 63 Female 2/26/2010 Pharmacist Spain
Primary
Concomitant
Lipodystrophy Acquired Other Serious 1/1/2010 51 Female 2/26/2010 Pharmacist Spain
Primary
Concomitant
Vertigo Other Serious 1/1/2009 69 Female 141 lb 3/2/2010 Physician Germany
Primary
Secondary
Concomitant
Myocardial Ischaemia Hospitalization 2/5/2010 63 Female 168 lb 3/2/2010 Physician Germany
Primary
Secondary
Concomitant
Leukopenia Other Serious 12/4/2007 38 Female 3/5/2010 Japan
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 9/15/2009 59 Female 3/12/2010 Other Health Professional France
Primary
Secondary
Vertigo Life Threatening 69 Female 3/9/2010 Other Health Professional Germany
Primary
Concomitant
Metastases To Spine Other Serious 11/19/2007 Female 3/25/2010 Physician Japan
Primary
Secondary
Concomitant
Paraneoplastic Syndrome Hospitalization Female 128 lb 3/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Nausea Death 76 Male 3/29/2010 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization Female 4/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Uterine Cancer Other Serious 2/11/2009 71 Female 4/8/2010 Physician Finland
Primary
Secondary
Vomiting Hospitalization Female 4/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Tinnitus Hospitalization 3/1/2010 34 Female 4/12/2010 Other Health Professional France
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 11/12/2009 50 Female 4/13/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization Female 4/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ejection Fraction Decreased Other Serious 9/15/2009 59 Female 5/3/2010 Other Health Professional France
Primary
Secondary
Visual Acuity Reduced Other Serious 53 Female 5/17/2010 Physician Denmark
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 53 Female 5/17/2010 Other Health Professional France
Primary
Secondary
Pain Other Serious Female 5/19/2010 Physician Denmark
Primary
Secondary
Liver Disorder Other Serious 1/2/2010 43 Female 5/20/2010 Physician Australia
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2005 51 Female 5/21/2010 Physician Japan
Primary
Secondary
Hyporeflexia Life Threatening 49 Female 190 lb 5/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pain Other Serious 1/1/2006 49 Female 5/24/2010 Other Health Professional Denmark
Primary
Secondary
Acute Myeloid Leukaemia Other Serious 68 Female 5/28/2010 Physician United States
Primary
Concomitant
Infusion Site Ulcer Hospitalization 63 Female 5/28/2010 Physician Spain
Primary
Concomitant
Skin Hyperpigmentation Other Serious 54 Female 6/29/2010 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Left Ventricular Failure Hospitalization 6/9/2010 57 Female 7/13/2010 Other Health Professional France
Primary
Secondary
Atrial Fibrillation Life Threatening 7/6/2010 31 Female 7/15/2010 Physician Japan
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Life Threatening 4/1/2008 58 Female 190 lb 7/30/2010 Physician France
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 1/1/2007 28 Female 97 lb 8/2/2010 Physician Japan
Primary
Secondary
Concomitant
Cardiomyopathy Life Threatening 12/1/2008 72 Female 8/2/2010 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/26/2007 50 Female 8/4/2010 Physician Japan
Primary
Concomitant
Cerebral Ischaemia Hospitalization 7/2/2010 Male 8/6/2010 Other Health Professional Italy
Primary
Secondary
Ventricular Fibrillation Other Serious 7/6/2010 31 Female 97 lb 8/10/2010 Physician Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Hospitalization 5/1/2010 50 Female 146 lb 8/11/2010 Pharmacist Germany
Primary
Secondary

Drug Data