Epinephrine combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 11/1/2005 57 Male 1/4/2006 Physician United Kingdom
Primary
Concomitant
Intestinal Infarction Death 2/9/2006 78 Male 170 lb 2/16/2006 Physician
Primary
Concomitant
Tachypnoea Death 2/9/2006 78 Male 170 lb 2/20/2006 Physician
Primary
Concomitant
Respiratory Failure Life Threatening 2/1/2006 63 Female 121 lb 2/14/2006 Physician United States
Primary
Concomitant
Pulmonary Haemorrhage Death 12/28/2005 58 Female 110 lb 2/9/2006 United Kingdom
Primary
Concomitant
Myoglobin Blood Increased Life Threatening 12/18/2005 44 Male 2/22/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 8/19/2005 66 Male 3/1/2006 Physician Switzerland
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Death 58 Female 110 lb 2/14/2006 Physician United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 5/1/2001 31 Male 183 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Urosepsis Death 3/25/2006 85 Male 163 lb 4/10/2006 Pharmacist Canada
Primary
Concomitant
Propofol Infusion Syndrome Death 27 Female 4/3/2006 Consumer United States
Primary
Secondary
Pulmonary Embolism Life Threatening 2/21/2006 74 Female 168 lb 4/12/2006 Physician Israel
Primary
Concomitant
Sudden Death Death 3/25/2006 85 Male 163 lb 4/18/2006 Pharmacist Canada
Primary
Concomitant
Urosepsis Death 3/25/2006 85 Male 163 lb 4/21/2006 Pharmacist Canada
Primary
Concomitant
Hypotension Other Serious 74 Female 110 lb 4/20/2006 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 6/13/2005 49 Female 265 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Wrong Drug Administered Other Serious 3/21/2006 35 Male 258 lb 5/1/2006 Physician United Kingdom
Primary
Concomitant
Blood Potassium Increased Life Threatening 2/21/2006 62 Female 223 lb 2/24/2006 United States
Primary
Concomitant
Urosepsis Death 3/25/2006 85 Male 163 lb 5/17/2006 Physician Canada
Primary
Concomitant
Pulse Absent Other Serious 2/6/2005 63 Male 5/22/2006 Pharmacist United States
Primary
Concomitant
Urosepsis Death 3/25/2006 85 Male 163 lb 6/2/2006 Physician Canada
Primary
Concomitant
Ventricular Tachycardia Required Intervention 5/6/2006 54 Male 143 lb 5/31/2006 Physician United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 67 Male 139 lb 6/8/2006 Japan
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 67 Male 139 lb 6/14/2006 Japan
Primary
Secondary
Concomitant
Splenectomy Other Serious 4/5/2005 37 Male 185 lb 6/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Intestinal Infarction Death 2/9/2006 78 Male 170 lb 6/30/2006 Physician
Primary
Concomitant
Therapy Non-responder Other Serious 74 Female 110 lb 6/29/2006 Physician Japan
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 35 Female 116 lb 9/28/2006 United States
Primary
Concomitant
Interacting
Tachypnoea Death 2/9/2006 78 Male 170 lb 11/6/2006 Physician
Primary
Concomitant
Rhabdomyolysis Death 24 Male 11/8/2006 Physician Switzerland
Primary
Secondary
Tracheomalacia Other Serious 66 Female 106 lb 11/17/2006 Physician Japan
Primary
Secondary
Intestinal Infarction Death 2/9/2006 Male 170 lb 11/29/2006 Physician
Primary
Concomitant
Ventricular Tachycardia Required Intervention 55 Female 12/29/2006 Physician United States
Primary
Concomitant
Intestinal Infarction Hospitalization 1/31/2006 Male 170 lb 2/7/2007 Physician
Primary
Concomitant
Neuropathy Peripheral Life Threatening 10/13/2006 Male 5/4/2007 Other Health Professional Norway
Primary
Concomitant
Device Failure 6/18/2007 6/27/2007 United States
Primary
Secondary
Respiratory Arrest Life Threatening 6/13/2007 8/30/2007 Consumer United States
Primary
Secondary
Concomitant
No Therapeutic Response Life Threatening 48 Female 9/10/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Death 29 Female 9/13/2007 Physician United States
Primary
Concomitant
Tachycardia Life Threatening 6/13/2007 9/18/2007 Physician United States
Primary
Secondary
Concomitant
Erythema Other Serious 10/2/2007 51 Male 183 lb 10/16/2007 Other Health Professional Japan
Primary
Concomitant
Post Procedural Haemorrhage Required Intervention 10/26/2007 65 Male 222 lb 11/6/2007 Physician United States
Primary
Concomitant
Ventricular Dysfunction Required Intervention 1 Male 9 lb 11/6/2007 Physician United States
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 10/31/2007 Female 243 lb 11/14/2007 Pharmacist United States
Primary
Concomitant
Shock Hospitalization 10/21/2007 Male 84 lb 11/13/2007 United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 10/21/2007 Male 84 lb 11/27/2007 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 8/24/2007 67 Female 1/9/2008 Other Health Professional United States
Primary
Concomitant
Thermal Burn Other Serious 10/31/2003 Male 2/22/2008 Physician Germany
Primary
Secondary
Shock Hospitalization 10/21/2007 Male 84 lb 2/20/2008 United States
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 58 Female 3/10/2008
Primary
Secondary
Concomitant
Thermal Burn Other Serious 10/31/2003 Male 3/12/2008 Physician Germany
Primary
Secondary
Haemorrhage Other Serious 6/28/2004 64 Male 4/29/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Right Ventricular Failure Life Threatening 2/1/2006 63 Female 121 lb 5/1/2008 Physician United States
Primary
Concomitant
Blood Pressure Decreased Other Serious 4/6/2007 61 Male 4/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 42 Female 6/5/2008 Physician Brazil
Primary
Concomitant
Vision Blurred Other Serious 29 Male 7/1/2008 Physician Mexico
Primary
Concomitant
Vision Blurred Other Serious 29 Male 176 lb 7/10/2008 Mexico
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 31 Female 8/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Dysfunction Required Intervention 29 Male 9/11/2008 Physician Canada
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 9/25/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/28/2008 67 Female 121 lb 9/25/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Hospitalization 77 Female 10/10/2008 United States
Primary
Secondary
Concomitant
Muscle Contractions Involuntary Other Serious 19 Male 10/15/2008 Japan
Primary
Secondary
Concomitant
Acute Hepatic Failure Hospitalization 1/18/2007 Male 10/16/2008 Physician United States
Primary
Concomitant
Vision Blurred Hospitalization 12/14/2007 Male 52 lb 11/4/2008 Other Health Professional Brazil
Primary
Concomitant
Muscle Contractions Involuntary Other Serious 19 Male 152 lb 11/14/2008 Japan
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Ventricular Hypokinesia Life Threatening Male 11/26/2008 Physician Canada
Primary
Secondary
Concomitant
Propofol Infusion Syndrome Other Serious 67 Male 168 lb 1/15/2009 Physician United Kingdom
Primary
Concomitant
Propofol Infusion Syndrome Other Serious 12 Female 1/23/2009 Other Health Professional France
Primary
Concomitant
Propofol Infusion Syndrome Other Serious 16 Female 1/23/2009 Other Health Professional France
Primary
Concomitant
Skin Test Positive Other Serious 44 Female 2/18/2009
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2007 71 Female 2/20/2009 Lawyer United States
Primary
Concomitant
Vomiting Required Intervention 20 Male 165 lb 2/17/2009 Physician United States
Primary
Secondary
Concomitant
Hypotonia Other Serious 3 NotSpecified 3/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 60 Female 119 lb 3/23/2009
Primary
Secondary
Hypotonia Other Serious 3 3/18/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Fluctuation Other Serious 1/1/2004 20 Male 160 lb 4/14/2009 United States
Primary
Concomitant
Stress Cardiomyopathy Required Intervention 46 Female 4/17/2009 Physician United States
Primary
Secondary
Concomitant
Stress Cardiomyopathy Other Serious 46 Female 4/21/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 35 Female 5/18/2009
Primary
Secondary
Concomitant
Device Failure Other Serious 4/6/2007 61 Male 5/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Long Qt Syndrome Life Threatening 35 Female 6/15/2009 United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 35 Female 6/18/2009 United Kingdom
Primary
Secondary
Concomitant
Long Qt Syndrome Life Threatening 35 Female 7/1/2009 United Kingdom
Primary
Secondary
Concomitant
Long Qt Syndrome Life Threatening 35 Female 7/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 50 Female 7/2/2009
Primary
Secondary
Concomitant
Nausea Other Serious 5/20/2009 65 Female 145 lb 6/30/2009 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 6/3/2009 72 Male 195 lb 6/30/2009 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 6/3/2009 71 Male 225 lb 6/30/2009 Other Health Professional United States
Primary
Concomitant
Hyperhidrosis Other Serious 5/20/2009 73 Female 159 lb 6/30/2009 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 6/10/2009 69 Female 190 lb 6/30/2009 Other Health Professional United States
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 6/10/2009 75 Male 185 lb 6/30/2009 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 6/10/2009 81 Male 155 lb 6/30/2009 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 6/3/2009 78 Female 133 lb 6/30/2009 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 6/10/2009 88 Female 140 lb 6/30/2009 Other Health Professional United States
Primary
Concomitant
Long Qt Syndrome Life Threatening 35 Female 7/13/2009 United Kingdom
Primary
Secondary
Concomitant
Tongue Oedema Hospitalization 50 Female 7/16/2009 Pharmacist United States
Primary
Concomitant
Heart Rate Decreased Other Serious 5/13/2009 79 Male 165 lb 8/4/2009 Other Health Professional United States
Primary
Concomitant
Anaphylactic Reaction Death 73 Male 8/7/2009 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Nausea Other Serious 5/6/2009 81 Female 123 lb 8/4/2009 Other Health Professional United States
Primary
Concomitant
Anaphylactic Reaction Death 73 Male 225 lb 8/27/2009 Other Health Professional Czech Republic
Primary
Secondary
Concomitant
Neuromuscular Block Prolonged Hospitalization 10/20/2009
Primary
Secondary
Concomitant
Pyrexia Hospitalization 50 Female 10/31/2009 Pharmacist United States
Primary
Concomitant
Long Qt Syndrome Life Threatening 35 Female 12/10/2009 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 71 Female 146 lb 12/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 11/4/2009 Female 98 lb 1/6/2010 Canada
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 35 Female 12/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2008 71 Female 2/3/2010 Other Health Professional United States
Primary
Concomitant
Tachycardia Hospitalization 50 Female 1/29/2010 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 2/18/2010 Lawyer United States
Primary
Concomitant
Long Qt Syndrome Life Threatening 35 Female 2/25/2010 United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2008 59 Female 2/26/2010 Lawyer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2003 42 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 81 Female 2/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Nerve Compression Hospitalization 75 Female 2/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Distress Life Threatening 7 Male 65 lb 4/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 7 Male 65 lb 4/13/2010
Primary
Secondary
Vomiting Other Serious 1/1/2005 71 Female 146 lb 4/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 5/3/2010 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Life Threatening 7 Male 65 lb 4/29/2010 Consumer United Kingdom
Primary
Secondary
Tracheostomy Life Threatening 7 Male 65 lb 4/29/2010 Consumer United Kingdom
Primary
Secondary
Ventricular Tachycardia Other Serious 49 Female 115 lb 5/11/2010 Physician Korea, Republic Of
Primary
Concomitant
Ventricular Fibrillation Other Serious 51 Female 126 lb 5/19/2010
Primary
Secondary
Drug Ineffective 60 Male 5/28/2010 Pharmacist United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2008 62 Male 6/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2008 73 Male 6/10/2010 Lawyer United States
Primary
Concomitant
Hypertension Other Serious 1/1/2008 65 Male 258 lb 6/15/2010 Lawyer United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/2008 68 Male 6/25/2010 Lawyer United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 1/23/2008 78 Female 7/13/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Septic Shock Life Threatening 1/13/2009 60 Male 103 lb 7/21/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Oxygen Saturation Decreased Death 7/3/2010 19 Male 110 lb 7/30/2010 Physician Indonesia
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 1/1/2008 72 Male 8/5/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 4/28/2008 74 Male 190 lb 8/6/2010 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 86 Female 8/4/2010 Germany
Primary
Secondary
Concomitant
Vascular Graft Occlusion Other Serious 2/1/2008 53 Male 203 lb 8/12/2010 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 1/1/2008 65 Male 258 lb 8/12/2010 Lawyer United States
Primary
Secondary
Concomitant
Temperature Perception Test Decreased Hospitalization 80 Female 8/19/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/1/2008 68 Male 8/20/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 10/1/2007 75 Male 9/2/2010 Lawyer United States
Primary
Concomitant
Serratia Infection Other Serious 1/1/2008 64 Male 165 lb 9/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/1/2008 78 Female 205 lb 9/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2008 71 Female 9/20/2010 Other Health Professional United States
Primary
Concomitant

Drug Data