Endoxan combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tooth Extraction Other Serious 1/15/2005 68 Female 1/18/2006 Physician Belgium
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 3/18/2005 66 Female 172 lb 2/18/2006 France
Primary
Concomitant
Treatment Related Secondary Malignancy Life Threatening 10/10/2005 70 Male 181 lb 2/21/2006 Consumer United States
Primary
Secondary
Concomitant
Toothache Other Serious 12/1/2004 Male 207 lb 6/17/2006 Physician Germany
Primary
Concomitant
Tooth Extraction Other Serious 10/1/2003 60 Female 7/21/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/14/2005 72 Female 176 lb 8/31/2006 France
Primary
Secondary
Tooth Loss Other Serious 1/1/2006 65 Female 9/12/2006 Physician Japan
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2006 65 Female 10/4/2006 Physician Japan
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2006 65 Female 10/25/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/1/2005 72 Female 176 lb 11/3/2006 France
Primary
Secondary
Deafness Neurosensory Other Serious 4/1/2006 61 Male 11/8/2006 Consumer United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2006 60 Male 12/7/2006 Physician Belgium
Primary
Concomitant
Osteonecrosis Disability 6/15/2004 52 Female 1/26/2007 France
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 1/1/2007 65 Female 1/31/2007 Physician Japan
Primary
Secondary
Uterine Neoplasm Hospitalization 12/1/2006 72 Female 115 lb 2/15/2007 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 1/1/2007 65 Female 2/19/2007 Consumer United States
Primary
Secondary
Liver Disorder Hospitalization 1/1/2007 65 Female 2/21/2007 Physician Japan
Primary
Secondary
Liver Disorder Hospitalization 12/1/2006 Female 2/28/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 12/1/2006 Female 3/7/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 12/1/2006 65 Female 3/12/2007 Consumer United States
Primary
Secondary
Concomitant
Myelocytosis Life Threatening 1/1/2007 74 Male 165 lb 3/23/2007 Consumer France
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 12/1/2006 65 Female 3/23/2007 Consumer United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 12/16/2006 Female 134 lb 4/16/2007 Physician Japan
Primary
Secondary
Concomitant
Wheezing Other Serious 12/16/2006 65 Female 4/25/2007 Consumer United States
Primary
Secondary
Concomitant
Myelocytosis Life Threatening 1/1/2007 74 Male 165 lb 5/7/2007 Consumer France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/1/2006 Male 5/14/2007 Physician Germany
Primary
Concomitant
Osteonecrosis Other Serious 10/1/2006 Male 5/14/2007 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/23/2006 53 Female 132 lb 5/22/2007 Japan
Primary
Secondary
Concomitant
Wound Debridement Other Serious 4/1/2007 70 Male 6/2/2007 Physician Belgium
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/23/2006 53 Female 132 lb 6/22/2007 Japan
Primary
Secondary
Concomitant
Waldenstrom's Macroglobulinaemia Hospitalization 8/4/2003 88 Male 165 lb 9/6/2007 Consumer Germany
Primary
Concomitant
Tooth Abscess Other Serious 1/1/2004 53 Female 9/29/2007 France
Primary
Secondary
Concomitant
Wound Treatment Disability 9/2/2007 68 Male 10/11/2007 Italy
Primary
Concomitant
Metrorrhagia 7/27/2007 68 Female 10/31/2007 Other Health Professional Italy
Primary
Concomitant
Toothache Other Serious 11/1/2006 65 Female 108 lb 11/14/2007 Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 12/17/2007 69 Male 1/23/2008 Consumer United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 1/1/2007 23 Female 1/23/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 56 Female 119 lb 3/19/2008 Physician Japan
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/12/2007 56 Female 119 lb 4/21/2008 Physician Japan
Primary
Secondary
Toothache Other Serious 11/1/2006 Female 108 lb 6/4/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/18/2006 Female 93 lb 6/4/2008 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 12/5/2006 Female 93 lb 6/17/2008 Physician Japan
Primary
Concomitant
Osteonecrosis Other Serious 4/1/2005 Male 117 lb 6/24/2008 Physician Japan
Primary
Concomitant
Osteonecrosis Other Serious 4/1/2005 Male 117 lb 7/3/2008 Physician Japan
Primary
Concomitant
Osteonecrosis Hospitalization 4/24/2008 66 Female 7/21/2008 Physician Japan
Primary
Concomitant
X-ray Dental Other Serious 12/28/2007 Female 7/31/2008 Other Health Professional France
Primary
Concomitant
Vision Blurred Hospitalization 6/5/2008 83 Female 8/13/2008 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 57 Female 8/13/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 57 Female 8/13/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/24/2007 57 Female 8/15/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 57 Female 8/20/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
X-ray Dental Other Serious 4/24/2007 Female 110 lb 9/4/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 4/24/2008 66 Female 9/9/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/2/2008 9/9/2008 Physician Japan
Primary
Concomitant
X-ray Dental Other Serious 4/24/2007 Female 110 lb 9/25/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 4/24/2008 Female 152 lb 10/3/2008 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/2/2008 10/3/2008 Physician Japan
Primary
Concomitant
X-ray Dental Other Serious 4/24/2007 Female 110 lb 10/23/2008 Japan
Primary
Secondary
Concomitant
X-ray Dental Other Serious 4/24/2007 Female 110 lb 10/31/2008 Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 11/1/2001 Female 110 lb 11/5/2008 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 11/1/2001 Female 110 lb 11/5/2008 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 3/1/2008 Female 104 lb 11/11/2008 Physician Japan
Primary
Secondary
Concomitant
Swelling Other Serious 11/1/2006 Female 117 lb 11/27/2008 Other Health Professional Japan
Primary
Concomitant
Swelling Other Serious 11/1/2006 Female 117 lb 12/15/2008 Other Health Professional Japan
Primary
Concomitant
Tooth Extraction Other Serious 3/1/2008 Female 104 lb 12/17/2008 Physician Japan
Primary
Secondary
Concomitant
Swelling Other Serious 11/1/2006 Female 117 lb 12/22/2008 Other Health Professional Japan
Primary
Concomitant
Osteonecrosis Other Serious 11/1/2008 Female 12/23/2008 Physician Switzerland
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 4/24/2008 Female 152 lb 1/7/2009 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/2/2008 Female 106 lb 1/7/2009 Physician Japan
Primary
Concomitant
Swelling Other Serious 11/1/2006 Female 117 lb 2/13/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Primary Sequestrum Other Serious 6/1/2007 71 Female 2/18/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Cerebral Infarction Life Threatening 11/21/2008 46 Female 90 lb 2/19/2009 Other Health Professional Japan
Primary
Concomitant
Tooth Extraction Other Serious 9/17/2008 Female 132 lb 3/16/2009 Physician Japan
Primary
Secondary
Concomitant
Shock Life Threatening 3/30/2009 26 Female 110 lb 4/29/2009 Physician Japan
Primary
Concomitant
Thrombocytopenia Other Serious 5/23/2008 Female 95 lb 5/11/2009 Physician Japan
Primary
Secondary
Concomitant
Swelling Other Serious 11/1/2006 Female 117 lb 5/12/2009 Japan
Primary
Secondary
Concomitant
Primary Sequestrum Other Serious 6/1/2007 Female 5/15/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Swelling Other Serious 11/1/2006 Female 117 lb 5/19/2009 Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 5/23/2008 Female 95 lb 5/20/2009 Physician Japan
Primary
Secondary
Concomitant
Primary Sequestrum Other Serious 6/1/2007 Female 5/22/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Primary Sequestrum Other Serious 6/1/2007 Female 6/8/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 5/29/2008 Female 97 lb 7/6/2009 Physician Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 5/29/2008 Female 97 lb 7/10/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 5/1/2008 Female 97 lb 7/15/2009 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 11/1/2007 Female 137 lb 8/10/2009 Other Health Professional Japan
Primary
Concomitant
Osteonecrosis Other Serious 7/13/2009 Female 130 lb 8/27/2009 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 11/1/2007 Female 137 lb 8/27/2009 Other Health Professional Japan
Primary
Concomitant
Tooth Extraction Other Serious 3/12/2009 66 Female 9/17/2009 Other Health Professional Japan
Primary
Concomitant
Tooth Extraction Other Serious 5/1/2008 Female 97 lb 9/17/2009 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 3/12/2009 Female 77 lb 9/28/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 7/13/2009 Female 130 lb 10/15/2009 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 3/12/2009 Female 77 lb 10/23/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 5/14/2009 65 Female 11/4/2009 Physician Japan
Primary
Secondary
Concomitant
Sequestrectomy Other Serious 7/13/2009 Female 130 lb 11/18/2009 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 9/1/2004 Female 12/21/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/1/2008 Female 97 lb 12/25/2009 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/1/2008 Female 97 lb 12/30/2009 Physician Japan
Primary
Secondary
Concomitant
Sequestrectomy Disability 12/1/2004 Male 12/31/2009 Other Health Professional Italy
Primary
Concomitant
Tooth Extraction Other Serious 9/1/2004 Female 12/31/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization Female 1/4/2010 Other Health Professional Italy
Primary
Concomitant
Sequestrectomy Disability 12/1/2004 Male 2/1/2010 Other Health Professional Italy
Primary
Concomitant
Osteonecrosis Hospitalization Female 2/3/2010 Other Health Professional Italy
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 68 Female 2/4/2010 Physician Switzerland
Primary
Concomitant
Monoplegia Other Serious 9/1/2008 36 Female 2/4/2010 Physician Japan
Primary
Secondary
Concomitant
Monoplegia Hospitalization 9/1/2008 36 Female 2/11/2010 Physician Japan
Primary
Secondary
Concomitant
Ulcer Disability 2/8/2007 Female 106 lb 2/24/2010 Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 1/27/2010 56 Female 106 lb 3/10/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 8/14/2009 56 Female 106 lb 3/22/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/4/2009 61 Female 134 lb 5/6/2010 Pharmacist Japan
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 8/11/2008 61 Female 6/24/2010 Other Health Professional Japan
Primary
Concomitant
Tooth Extraction Other Serious 5/1/2008 63 Female 97 lb 7/8/2010 Physician Japan
Primary
Secondary
Concomitant
Toothache Other Serious 10/1/2009 61 Female 8/20/2010 Other Health Professional France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/24/2007 72 Female 101 lb 8/30/2010 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 7/1/2008 65 Female 141 lb 8/30/2010 Other Health Professional Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious Female 8/31/2010 Physician Japan
Primary
Concomitant
Tooth Extraction Other Serious 7/1/2008 65 Female 141 lb 9/9/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/24/2007 72 Female 101 lb 9/9/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Breast Cancer Female Death 5/31/2008 53 Female 9/14/2010 Physician Japan
Primary
Concomitant
Transaminases Increased Other Serious 12/1/2008 47 9/16/2010 Other Health Professional Italy
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/25/2006 71 Female 101 lb 9/20/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Breast Cancer Female Death 5/31/2008 53 Female 114 lb 9/24/2010 Physician Japan
Primary
Concomitant
Osteonecrosis Disability 1/1/2010 76 Female 154 lb 10/15/2010 Physician Switzerland
Primary
Secondary
Concomitant
Osteonecrosis Disability 1/1/2010 Female 154 lb 10/22/2010 Physician Switzerland
Primary
Secondary
Concomitant
Prostate Cancer Stage Iv Death 55 Male 10/22/2010 Other Health Professional Japan
Primary
Concomitant
Paraesthesia Oral Other Serious 5/1/2010 Female 10/26/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 9/1/2010 76 Female 119 lb 11/2/2010 Physician Japan
Primary
Concomitant
Tumour Marker Increased Other Serious 8/11/2008 61 Female 11/29/2010 Other Health Professional Japan
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 1/1/2010 Female 12/8/2010 Physician Switzerland
Primary
Concomitant
No Therapeutic Response Other Serious Male 12/8/2010 Consumer South Africa
Primary
Secondary
Tumour Marker Increased Other Serious 8/11/2008 61 Female 12/10/2010 Other Health Professional Japan
Primary
Concomitant
Tumour Marker Increased Other Serious 8/11/2008 61 Female 12/22/2010 Other Health Professional Japan
Primary
Concomitant
No Therapeutic Response Other Serious 6/7/2006 Male 12/23/2010 Physician South Africa
Primary
Secondary
Wound Treatment Other Serious 8/20/2010 50 Female 117 lb 1/11/2011 Physician Japan
Primary
Secondary
Concomitant
No Therapeutic Response Disability 6/7/2006 54 Male 1/12/2011 Physician South Africa
Primary
Secondary
Osteonecrosis Of Jaw Death 4/9/2010 50 Female 117 lb 1/13/2011 Physician Japan
Primary
Concomitant
Cerebral Arteriosclerosis Hospitalization 7/9/2009 69 Female 101 lb 1/18/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 1/1/2009 68 Female 101 lb 1/21/2011 Physician Japan
Primary
Concomitant
Blood Creatinine Increased Other Serious 9/22/2004 59 Female 126 lb 1/26/2011 Other Health Professional France
Primary
Secondary
Haematocrit Decreased Death 1/1/2009 64 Female 143 lb 1/28/2011 Physician Japan
Primary
Concomitant
Hepatic Failure Hospitalization 9/16/2010 47 Female 108 lb 2/10/2011 Other Health Professional Japan
Primary
Concomitant
Blood Urea Increased Other Serious 1/14/2009 64 Female 143 lb 3/15/2011 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 9/22/2004 59 Female 126 lb 1/25/2011 Other Health Professional France
Primary
Secondary
Infection Life Threatening 4/9/2010 50 Female 117 lb 3/22/2011 Other Health Professional Japan
Primary
Concomitant
Osteonecrosis Of Jaw Hospitalization 8/11/2008 61 Female 4/5/2011 Other Health Professional Japan
Primary
Concomitant
Osteonecrosis Of Jaw Other Serious 12/25/2007 70 Female 106 lb 4/8/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/10/2010 49 Female 4/13/2011 Physician Japan
Primary
Secondary
Concomitant
Injury Other Serious 8/11/2008 61 Female 4/13/2011 Japan
Primary
Concomitant
Ulcer Disability 2/20/2007 53 Female 106 lb 4/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/10/2010 49 Female 4/20/2011 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 3/10/2010 49 Female 4/27/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data