Endoxan combined with Fludara

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Treatment Related Secondary Malignancy Other Serious 1/1/2004 64 Male 3/23/2006 Consumer United States
Primary
Concomitant
Sepsis Life Threatening 4/19/2005 3 Male 3/31/2006 Consumer United States
Primary
Concomitant
Sepsis Life Threatening 4/19/2005 3 Male 4/14/2006 Consumer United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 2/1/2005 0 Male 5/10/2006 Consumer United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Hospitalization 2/1/2005 0 Male 6/5/2006 Consumer United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 2/1/2005 0 Male 7/3/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Tubular Acidosis Other Serious 5/5/2005 20 Male 8/3/2006 Consumer United States
Primary
Secondary
Concomitant
Oral Mucosal Disorder Hospitalization 2/9/2006 10 Male 8/7/2006 Consumer United States
Primary
Secondary
Concomitant
Malaise Hospitalization 9/5/2005 57 Male 8/14/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Tubular Acidosis Other Serious 5/5/2005 20 Male 8/30/2006 Consumer United States
Primary
Secondary
Concomitant
Oral Mucosal Disorder Hospitalization 2/9/2006 10 Male 8/30/2006 Consumer United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 4/19/2005 3 Male 9/8/2006 Consumer United States
Primary
Concomitant
Sepsis Life Threatening 4/19/2005 3 Male 9/20/2006 Consumer United States
Primary
Concomitant
Dermatitis Allergic Hospitalization 10/1/2006 Male 11/10/2006 Other Health Professional Italy
Primary
Concomitant
Sicca Syndrome Other Serious 3/1/2004 51 Female 12/6/2006 Physician France
Primary
Concomitant
Skin Lesion Other Serious 3/1/2004 54 Female 143 lb 12/19/2006 Physician France
Primary
Concomitant
Rash Hospitalization 10/1/2006 Male 1/11/2007 Other Health Professional Italy
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/12/2006 70 Female 1/16/2007 Consumer United States
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 10/30/2006 71 Female 3/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 8/16/2006 71 Female 4/23/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/9/2007 78 Female 6/5/2007 Other Health Professional France
Primary
Concomitant
Neoplasm Malignant Life Threatening 4/13/2007 70 Male 6/18/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/9/2007 78 Female 99 lb 6/18/2007 Other Health Professional France
Primary
Concomitant
Toxic Skin Eruption Hospitalization 5/20/2007 60 Male 6/21/2007 Consumer France
Primary
Secondary
Transitional Cell Carcinoma Other Serious 4/13/2007 70 Male 6/21/2007 Consumer United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 5/20/2007 60 Male 6/25/2007 Physician France
Primary
Secondary
Pulmonary Fibrosis Life Threatening 11/20/2006 Female 8/13/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Fibrosis Life Threatening 11/20/2006 Female 8/27/2007 Physician France
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 1/1/2007 70 Female 168 lb 9/26/2007 Germany
Primary
Secondary
Lung Disorder Hospitalization 8/26/2006 67 Female 10/2/2007 Consumer United States
Primary
Secondary
Staphylococcal Sepsis Life Threatening 8/1/2007 70 Female 10/11/2007 Consumer United States
Primary
Secondary
Cardiac Failure Other Serious 6/29/2006 2 Male 10/18/2007 Consumer United States
Primary
Secondary
Concomitant
Subarachnoid Haemorrhage Other Serious 5/14/2007 25 Female 115 lb 10/30/2007 Physician Japan
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 12/24/2007 51 Male 198 lb 1/17/2008 Physician Italy
Primary
Secondary
Transaminases Increased Hospitalization 12/24/2007 51 Male 198 lb 1/29/2008 Physician Italy
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 10/1/2005 68 Male 2/7/2008 Consumer United States
Primary
Secondary
Renal Failure Acute Life Threatening 11/13/2007 77 Male 2/15/2008 Consumer France
Primary
Secondary
Concomitant
Skin Exfoliation Hospitalization 11/15/2007 92 Male 2/22/2008 Consumer France
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 10/15/2005 68 Male 2/29/2008 Consumer United States
Primary
Secondary
Respiratory Failure Other Serious 10/15/2005 69 Male 168 lb 4/25/2008 Physician Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 10/15/2005 68 Male 5/8/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/1/2008 59 Male 6/10/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 11/13/2007 77 Male 6/23/2008 Consumer France
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 1/1/2008 Male 7/18/2008 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 5/6/2007 59 Female 7/21/2008 Other Health Professional France
Primary
Concomitant
Wheezing Life Threatening 11/20/2006 55 Female 8/18/2008 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Life Threatening 11/20/2006 Female 8/20/2008 Physician France
Primary
Secondary
Concomitant
Cardiomegaly Disability 4/16/2007 46 Female 108 lb 9/19/2008 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 2/1/2008 71 Female 112 lb 5/28/2008 Other Health Professional Japan
Primary
Concomitant
Renal Disorder Other Serious 7/12/2005 78 Female 112 lb 10/8/2008 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/10/2004 59 Male 123 lb 10/17/2008 Japan
Primary
Concomitant
Subdural Haematoma Life Threatening 8/14/2008 60 Male 152 lb 10/21/2008 Physician France
Primary
Secondary
Septic Shock Other Serious 8/28/2008 63 Male 146 lb 10/21/2008 Physician France
Primary
Secondary
Anaemia Hospitalization 5/14/2008 Female 10/29/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Febrile Neutropenia Other Serious 12/8/2008 France
Primary
Secondary
Febrile Neutropenia Other Serious 12/9/2008 France
Primary
Secondary
Urinary Tract Infection Hospitalization 5/15/2008 54 Female 12/11/2008 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/10/2008 67 Male 12/12/2008 France
Primary
Secondary
Vomiting Hospitalization 10/6/2008 52 Male 190 lb 12/22/2008 Physician France
Primary
Secondary
Concomitant
Anaemia Hospitalization 5/14/2008 Female 12/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/10/2008 67 Male 12/23/2008 Physician France
Primary
Secondary
Pyrexia Hospitalization 3/3/2008 59 Male 172 lb 12/23/2008 Physician France
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 5/1/2007 60 Male 1/13/2009 Other Health Professional France
Primary
Secondary
Thrombocytopenia Hospitalization 12/31/2008 62 Female 106 lb 1/16/2009 Physician France
Primary
Secondary
Thrombocytopenia Hospitalization 12/31/2008 62 Female 106 lb 1/16/2009 Physician France
Primary
Secondary
Haemorrhagic Stroke Death 57 Male 1/16/2009 Physician France
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/15/2008 54 Female 1/19/2009 Physician Japan
Primary
Secondary
Concomitant
Haemorrhagic Stroke Death 57 Male 1/27/2009 Physician France
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 9/1/2008 66 Male 1/27/2009 Consumer France
Primary
Secondary
Varicella Other Serious 2/1/2008 39 Male 1/28/2009 Consumer France
Primary
Secondary
Varicella Other Serious 2/1/2008 39 Male 2/6/2009 Consumer France
Primary
Secondary
Thrombocytopenia Hospitalization 12/31/2008 62 Female 106 lb 2/9/2009 Physician France
Primary
Secondary
Thrombocytopenia Hospitalization 11/10/2008 67 Male 2/9/2009 Physician France
Primary
Secondary
Acute Pulmonary Oedema Hospitalization 10/29/2008 60 Male 2/16/2009 Physician United States
Primary
Secondary
Aplasia Hospitalization 7/9/2008 Male 3/12/2009 Physician United Kingdom
Primary
Secondary
Ventricular Fibrillation Life Threatening 3/4/2009 68 Male 168 lb 3/24/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Renal Failure Life Threatening 8/12/2008 71 Male 4/20/2009 Japan
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 7/9/2008 Male 4/23/2009 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 11/4/2008 55 Female 119 lb 4/29/2009 Pharmacist Japan
Primary
Concomitant
Polyneuropathy Other Serious 2/24/2009 74 Male 5/11/2009 Consumer France
Primary
Secondary
Concomitant
Sepsis Other Serious 9/21/2008 30 Female 117 lb 5/11/2009 Japan
Primary
Concomitant
Bronchopulmonary Aspergillosis Hospitalization 8/1/2008 Female 5/11/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Infection Other Serious 4/1/2008 Male 5/11/2009 Physician France
Primary
Secondary
Concomitant
Sepsis Other Serious 9/21/2008 30 Female 117 lb 5/12/2009 Japan
Primary
Concomitant
Toxic Skin Eruption Hospitalization 3/19/2009 76 Male 5/12/2009 Consumer France
Primary
Secondary
Concomitant
Polyneuropathy Other Serious 2/24/2009 74 Male 5/12/2009 Consumer France
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/17/2009 Female 5/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization 2/24/2009 Male 5/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 3/19/2008 Male 5/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Haemorrhagic Stroke Hospitalization 12/3/2008 57 Male 5/29/2009 Physician France
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 2/1/2009 70 Female 121 lb 6/4/2009 Physician France
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 1/31/2009 70 Female 121 lb 6/9/2009 Physician France
Primary
Secondary
Concomitant
Haemolysis Other Serious 5/26/2008 Male 7/7/2009 Physician France
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Infection Other Serious 4/1/2008 Male 7/7/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 3/19/2008 Male 7/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Bronchopulmonary Aspergillosis Hospitalization 8/1/2008 Female 7/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Life Threatening 8/12/2008 71 Male 8/4/2009 Japan
Primary
Secondary
Traumatic Haematoma Other Serious 11/1/2008 83 Male 132 lb 8/11/2009 Consumer France
Primary
Secondary
Concomitant
No Adverse Event Hospitalization 4/11/2009 82 Male 8/18/2009 Consumer France
Primary
Secondary
Status Epilepticus Life Threatening 6/22/2009 Male 8/26/2009 Other Health Professional France
Primary
Secondary
Pleural Effusion Other Serious 6/1/2009 80 Male 154 lb 8/28/2009 Consumer France
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Life Threatening 6/1/2009 Male 8/28/2009 Physician United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Life Threatening 6/1/2009 Male 9/2/2009 Physician United Kingdom
Primary
Secondary
Hepatic Function Abnormal Other Serious 8/1/2008 54 Male 128 lb 9/4/2009 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/17/2009 Female 9/8/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 4/1/2009 74 Male 9/10/2009 Physician United Kingdom
Primary
Secondary
Sepsis Other Serious 9/21/2008 30 Female 117 lb 9/18/2009 Japan
Primary
Concomitant
Polyneuropathy Hospitalization 3/1/2009 65 Female 9/23/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Septic Shock Other Serious 54 Male 9/25/2009 Physician Poland
Primary
Secondary
Concomitant
Sinusitis Hospitalization 1/1/2008 16 Male 117 lb 9/28/2009 Physician Japan
Primary
Secondary
Concomitant
Extrapyramidal Disorder Hospitalization 5/12/2009 62 Male 10/1/2009 Consumer France
Primary
Secondary
Somnolence Other Serious 9/18/2009 50 Female 10/1/2009 Physician France
Primary
Secondary
Nervous System Disorder Hospitalization 5/12/2009 62 Male 10/1/2009 Other Health Professional France
Primary
Secondary
Septic Shock Other Serious 54 Male 10/2/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Convulsion Life Threatening 6/30/2009 Male 10/14/2009 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 3/1/2009 65 Female 132 lb 10/14/2009 Other Health Professional Germany
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Life Threatening 6/1/2009 Male 10/14/2009 Physician United Kingdom
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Life Threatening 6/1/2009 Male 10/20/2009 Physician France
Primary
Secondary
Agranulocytosis Other Serious 1/1/2009 154 lb 11/20/2009 Physician United Kingdom
Primary
Concomitant
Precursor T-lymphoblastic Lymphoma/leukaemia Death 2/1/2009 12 Male 1/18/2010 Physician Japan
Primary
Concomitant
Swelling Face Other Serious 8/1/2009 Male 2/10/2010 Consumer France
Primary
Concomitant
Pneumonia Other Serious 6/15/2009 72 Male 3/23/2010 Physician Japan
Primary
Concomitant
Neutropenia Other Serious 1/1/2009 60 Female 172 lb 5/6/2010 Consumer France
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Death 2/1/2009 71 Female 110 lb 5/6/2010 Consumer Netherlands
Primary
Secondary
Concomitant
Skin Exfoliation Hospitalization 4/1/2010 65 Male 6/14/2010 Consumer France
Primary
Secondary
Concomitant
Hypernatraemia Hospitalization 8/15/2008 72 Male 6/23/2010 Physician Japan
Primary
Secondary
Concomitant
Hypernatraemia Hospitalization 8/15/2008 72 Male 6/24/2010 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious 2/25/2009 55 Male 6/30/2010 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 12/1/2009 70 Female 174 lb 8/17/2010 Physician United Kingdom
Primary
Secondary
Myelodysplastic Syndrome Life Threatening 1/1/2010 72 Male 9/27/2010 Physician United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious 1/1/2010 73 Male 10/1/2010 Physician France
Primary
Secondary
Thrombocytopenia Other Serious 1/1/2010 73 Male 10/5/2010 Physician France
Primary
Secondary
Respiratory Failure Other Serious 8/1/2009 47 Male 10/7/2010 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2010 72 Male 11/8/2010 Other Health Professional Germany
Primary
Secondary
Alanine Aminotransferase Increased Hospitalization 12/1/2010 63 Male 143 lb 1/3/2011 Physician Japan
Primary
Secondary
Fall Life Threatening 10/16/2010 53 Male 1/31/2011 Other Health Professional France
Primary
Secondary
Pyrexia Hospitalization 10/16/2010 53 Male 2/7/2011 Other Health Professional France
Primary
Secondary
Basal Cell Carcinoma Other Serious 6/14/2010 72 Male 2/14/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Convulsion Hospitalization 12/18/2010 61 Female 2/18/2011 Other Health Professional France
Primary
Secondary
Precursor T-lymphoblastic Lymphoma/leukaemia Death 2/1/2009 12 Male 3/2/2011 Physician Japan
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 11/20/2006 55 Female 3/11/2011 Consumer France
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 3/22/2011 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 3/22/2011 Physician Japan
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 3/22/2011 Physician Japan
Primary
Concomitant
Pancytopenia Hospitalization 9/1/2010 76 Female 3/30/2011 Other Health Professional France
Primary
Secondary
Concomitant
Squamous Cell Carcinoma Other Serious 3/22/2010 73 Male 4/1/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 1/12/2011 73 Male 4/5/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Lung Disorder Death 11/14/2010 61 Female 4/7/2011 Other Health Professional France
Primary
Secondary
Concomitant
Apnoea Death 11/14/2010 61 Female 4/8/2011 Other Health Professional France
Primary
Secondary
Concomitant
Lung Disorder Other Serious 11/14/2010 61 Female 4/13/2011 Other Health Professional France
Primary
Secondary
Concomitant

Drug Data