Enbrel combined with Leflunomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Endocarditis Enterococcal Hospitalization 78 Female 1/19/2006 United States
Primary
Secondary
Respiratory Failure Life Threatening 5/30/2005 Male 168 lb 1/27/2006 Physician United Kingdom
Primary
Concomitant
Movement Disorder Hospitalization 11/26/2005 Female 2/10/2006 Physician United Kingdom
Primary
Secondary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 2/28/2006 Other Health Professional France
Primary
Secondary
Concomitant
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 2/28/2006 Consumer United States
Primary
Secondary
Concomitant
Arthritis Bacterial Hospitalization 11/28/2005 Female 3/9/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Colitis Ulcerative Other Serious 1/1/2006 Female 4/14/2006 Physician United Kingdom
Primary
Secondary
T-cell Lymphoma Stage Iv Hospitalization 4/1/2004 65 Male 4/25/2006 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Granuloma Other Serious 56 Male 5/3/2006 United States
Primary
Concomitant
Uveitis Other Serious Female 5/4/2006 Other Health Professional Australia
Primary
Concomitant
Tooth Extraction Disability 12/22/2005 52 Female 5/23/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Synovectomy Hospitalization 11/10/2005 34 Female 5/24/2006 Physician Germany
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 5/1/2006 Female 7/24/2006 Physician Belgium
Primary
Concomitant
Synovitis Other Serious 10/1/1999 77 Female 7/13/2006
Primary
Secondary
Wound Dehiscence Life Threatening 10/17/2005 67 Male 8/14/2006 Other Health Professional Germany
Primary
Concomitant
Bronchospasm Hospitalization 12/12/2005 36 Male 8/30/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Bronchospasm Hospitalization 12/12/2005 36 Male 9/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 7/24/2006 Female 106 lb 9/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 1/1/2006 59 Female 192 lb 9/29/2006 Physician United States
Primary
Secondary
Concomitant
Rash Generalised Hospitalization 9/27/2006 Female 119 lb 10/12/2006 Consumer Argentina
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 59 Male 10/19/2006 United States
Primary
Secondary
Concomitant
Streptococcal Infection Life Threatening 6/1/2006 Female 10/20/2006 Physician Australia
Primary
Concomitant
Sepsis Hospitalization 1/1/2006 59 Female 192 lb 11/1/2006 Physician United States
Primary
Secondary
Concomitant
Vulvar Dysplasia Other Serious 4/1/2006 51 Female 11/8/2006 Physician Turkey
Primary
Concomitant
Coronary Artery Disease Hospitalization 11/25/2005 Female 146 lb 11/13/2006 Physician United Kingdom
Primary
Concomitant
Prostate Cancer Other Serious 11/1/2006 Male 12/6/2006 Physician United States
Primary
Concomitant
Vulval Cancer Other Serious 1/1/2006 Female 182 lb 12/13/2006 Physician United States
Primary
Concomitant
Cutaneous Lupus Erythematosus Other Serious Female 12/13/2006 United States
Primary
Secondary
Concomitant
Injection Site Pain 8/5/2006 Male 12/13/2006 Consumer United States
Primary
Concomitant
Rash Generalised 10/21/2006 Female 12/14/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 9/27/2003 60 Male 12/18/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2003 65 Female 12/18/2006 United States
Primary
Concomitant
Pyrexia Hospitalization 10/9/2006 Female 12/20/2006 Physician
Primary
Concomitant
Injection Site Bruising 9/14/2006 Female 12/20/2006 Consumer United States
Primary
Concomitant
Cellulitis Hospitalization 11/15/2006 Female 174 lb 1/16/2007 Physician United Kingdom
Primary
Concomitant
Mitral Valve Incompetence Hospitalization 12/15/2006 Female 174 lb 1/19/2007 Physician United Kingdom
Primary
Concomitant
Scab Other Serious 7/14/2006 39 Male 1/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vasculitis Other Serious 1/1/2006 Male 163 lb 1/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 1/2/2007 Female 1/31/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Colitis Ulcerative Other Serious 12/19/2006 Male 2/1/2007 Physician Czech Republic
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/17/2005 Female 145 lb 2/7/2007 Physician Canada
Primary
Concomitant
Septic Shock Hospitalization 1/2/2007 Female 2/8/2007 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Life Threatening 6/1/2006 Female 245 lb 2/12/2007 Physician United Kingdom
Primary
Concomitant
Pulmonary Oedema Hospitalization 12/1/2006 Female 185 lb 3/8/2007 Physician United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 41 Female 3/9/2007 Physician Canada
Primary
Concomitant
Rheumatoid Arthritis Other Serious 41 Female 3/12/2007 Physician Canada
Primary
Concomitant
Hemiplegia Hospitalization 10/1/2005 Female 3/20/2007 Physician Costa Rica
Primary
Concomitant
Single Functional Kidney Other Serious 12/8/2005 Male 4/19/2007 Other Health Professional United States
Primary
Concomitant
Pulmonary Fibrosis Life Threatening 6/1/2005 Male 187 lb 4/23/2007 Physician Canada
Primary
Concomitant
Tongue Blistering Other Serious Female 6/4/2007 Physician United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 1/2/2007 Female 6/4/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Lung Neoplasm Other Serious 6/1/2006 82 Female 190 lb 6/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Demyelination Other Serious 5/19/2007 Male 6/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tuberculosis Other Serious 1/1/2007 Male 6/20/2007 Pharmacist United States
Primary
Concomitant
Demyelination Other Serious 5/19/2007 Male 145 lb 6/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Optic Neuritis Other Serious 5/19/2007 Male 145 lb 7/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Peripheral T-cell Lymphoma Unspecified Life Threatening 8/1/2000 Female 119 lb 7/19/2007 Physician France
Primary
Secondary
Subcutaneous Nodule Other Serious 50 Male 7/26/2007 Physician Netherlands
Primary
Concomitant
Photophobia Hospitalization 1/1/2007 44 Female 115 lb 8/6/2007 Physician Switzerland
Primary
Secondary
Concomitant
Rash Pruritic Hospitalization 10/21/2006 Female 8/20/2007 Physician United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 4/1/2007 Female 140 lb 8/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 7/1/2007 42 Female 8/23/2007 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2007 Female 8/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vasculitis Other Serious 1/1/2006 Male 163 lb 8/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tuberculosis Skin Test Positive Hospitalization 5/1/2006 Female 166 lb 9/14/2007 Physician United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 4/25/2007 75 Female 132 lb 9/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Uveitis Other Serious 1/1/2007 Female 143 lb 10/25/2007 Physician Australia
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2007 76 Female 197 lb 10/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 11/6/2007 Consumer United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 4/20/2006 Female 165 lb 11/15/2007 Physician United States
Primary
Concomitant
Foot Fracture Disability 8/1/2007 167 lb 11/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Wound Infection Other Serious 9/22/2006 Female 12/6/2007 Consumer United States
Primary
Concomitant
Injection Site Pain 11/29/2006 Female 12/7/2007 Consumer United States
Primary
Concomitant
Dyspnoea 3/25/2007 Female 12/8/2007 Consumer United States
Primary
Concomitant
Injection Site Erythema 4/30/2007 Female 12/8/2007 Consumer United States
Primary
Concomitant
Injection Site Pruritus 6/10/2007 Female 12/8/2007 Consumer United States
Primary
Concomitant
Rash Pruritic 6/25/2007 Male 12/8/2007 Consumer United States
Primary
Concomitant
Sinusitis 8/13/2007 Female 12/8/2007 Consumer United States
Primary
Concomitant
Headache 1/1/2007 Male 12/10/2007 Consumer United States
Primary
Concomitant
Weight Increased 1/1/2004 Female 12/10/2007 Consumer United States
Primary
Concomitant
Eczema Nummular 12/11/2007 Physician United States
Primary
Concomitant
Toothache 2/18/2007 Female 12/11/2007 Consumer United States
Primary
Concomitant
Injection Site Irritation 3/10/2007 Female 12/11/2007 Consumer United States
Primary
Concomitant
Joint Swelling 2/1/2007 Female 12/12/2007 Consumer United States
Primary
Concomitant
Injection Site Warmth 5/8/2007 Female 12/12/2007 Consumer United States
Primary
Concomitant
Hepatocellular Damage 1/1/2007 Female 143 lb 12/12/2007 Physician United States
Primary
Concomitant
Blood Glucose Abnormal 6/17/2007 Female 12/12/2007 Consumer United States
Primary
Concomitant
Skin Irritation 6/19/2007 Female 12/12/2007 Consumer United States
Primary
Concomitant
Ichthyosis 9/1/2006 Female 12/13/2007 Other Health Professional United States
Primary
Concomitant
Pyrexia 6/10/2007 Female 12/13/2007 Consumer United States
Primary
Concomitant
Injection Site Bruising 8/2/2007 Female 12/13/2007 Consumer United States
Primary
Concomitant
Joint Swelling 7/11/2007 Female 12/13/2007 Consumer United States
Primary
Concomitant
Neuroma 6/1/2007 Female 12/13/2007 Physician United States
Primary
Concomitant
Skin Lesion 8/12/2007 Female 12/14/2007 Consumer United States
Primary
Concomitant
Injection Site Irritation 9/6/2007 Female 12/14/2007 Consumer United States
Primary
Concomitant
Dyspnoea 10/19/2007 Female 12/15/2007 Consumer United States
Primary
Concomitant
Injection Site Swelling 10/4/2007 Female 12/15/2007 Consumer United States
Primary
Concomitant
Rheumatoid Nodule Other Serious 70 Female 12/18/2007 Other Health Professional France
Primary
Concomitant
Pain In Extremity Hospitalization 5/6/2007 55 Male 12/21/2007 Physician United Kingdom
Primary
Concomitant
Sinusitis Other Serious 10/2/2007 Female 1/3/2008 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 6/1/2007 Male 1/17/2008 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2007 Female 1/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis Other Serious 4/20/2006 Female 165 lb 2/6/2008 Physician United States
Primary
Concomitant
Systemic Lupus Erythematosus Rash Other Serious 1/22/2008 Female 2/12/2008 Consumer United States
Primary
Concomitant
Mononeuropathy Other Serious 43 Male 2/15/2008 Other Health Professional United States
Primary
Concomitant
Sinusitis Other Serious 10/2/2007 Female 2/25/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2007 Male 221 lb 2/26/2008 Consumer United States
Primary
Concomitant
Uterine Prolapse Hospitalization 1/1/2004 Female 3/7/2008 Consumer United States
Primary
Concomitant
Overweight Hospitalization Female 3/12/2008 Consumer United States
Primary
Concomitant
Vulvar Dysplasia Other Serious 4/1/2006 51 Female 3/14/2008 Other Health Professional Turkey
Primary
Concomitant
Osteoarthritis Other Serious 10/10/2007 Female 3/14/2008 Consumer United States
Primary
Concomitant
Lumbar Spinal Stenosis Hospitalization 10/1/2006 Female 3/25/2008 Consumer United States
Primary
Concomitant
Osteoarthritis Other Serious 10/10/2007 Female 3/25/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Abnormal Hospitalization 5/6/2007 Male 229 lb 3/25/2008 Physician United Kingdom
Primary
Concomitant
Rheumatoid Nodule Hospitalization 1/1/2003 Female 4/2/2008 Consumer United States
Primary
Concomitant
Intestinal Resection Hospitalization 1/1/2002 Male 4/4/2008 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization Male 4/11/2008 Consumer United States
Primary
Concomitant
Neuralgic Amyotrophy Hospitalization 11/1/2006 50 Male 137 lb 4/11/2008 Physician Turkey
Primary
Concomitant
Cerebrovascular Accident Hospitalization 2/9/2008 Male 4/29/2008 Physician United States
Primary
Concomitant
Rash Hospitalization 6/1/2006 54 Female 5/1/2008 Other Health Professional Japan
Primary
Secondary
Weight Increased Other Serious 1/1/2007 Female 168 lb 5/2/2008 Physician United States
Primary
Concomitant
Femoral Neck Fracture Hospitalization 2/1/2008 62 Female 5/5/2008 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 2/1/2008 Male 5/12/2008 Physician
Primary
Concomitant
Pleuritic Pain Hospitalization 9/15/2006 Male 225 lb 5/12/2008 Physician United Kingdom
Primary
Concomitant
Pleuritic Pain Hospitalization 9/15/2006 Male 225 lb 5/19/2008 Physician United Kingdom
Primary
Concomitant
Sensory Loss Other Serious 5/23/2007 Male 251 lb 6/20/2008 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 5/16/2006 Female 121 lb 6/23/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/2/2007 49 Female 6/30/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 4/1/2001 41 Female 7/2/2008 Other Health Professional Japan
Primary
Concomitant
Vomiting Hospitalization 5/16/2006 Female 121 lb 7/8/2008 Japan
Primary
Secondary
Concomitant
Lung Neoplasm Other Serious 9/12/2005 53 Female 7/10/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/2/2008 49 Female 7/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal Other Serious 3/1/2007 87 Female 139 lb 7/18/2008 Physician United States
Primary
Secondary
Concomitant
Coronary Artery Disease Other Serious 7/1/2008 Male 7/22/2008 Consumer United States
Primary
Concomitant
Loss Of Consciousness Other Serious 6/1/2007 Female 130 lb 7/23/2008 Consumer Canada
Primary
Concomitant
Meningitis Tuberculous Hospitalization 11/8/2006 Female 170 lb 8/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/1/2006 Male 321 lb 8/19/2008 Physician United States
Primary
Concomitant
Tinnitus Other Serious 6/1/2007 Female 130 lb 8/22/2008 Consumer Canada
Primary
Concomitant
Hallucination Other Serious 8/14/2008 Female 8/25/2008 Consumer United States
Primary
Concomitant
Hyperglycaemia Hospitalization 8/1/2004 75 Female 8/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 10 Female 8/27/2008 Physician United States
Primary
Secondary
Concomitant
Femur Fracture Hospitalization 6/24/2008 Female 9/2/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 3/1/2007 Female 148 lb 9/17/2008 Physician United States
Primary
Secondary
Concomitant
Iridocyclitis Other Serious 1/1/2006 Female 9/23/2008 Physician United Kingdom
Primary
Concomitant
Surgery Hospitalization 1/1/2008 62 Female 9/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 148 lb 9/24/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 1/2/2007 49 Female 10/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/1/2006 Male 321 lb 10/2/2008 Physician United States
Primary
Concomitant
Iridocyclitis Other Serious 5/1/2006 Female 99 lb 10/7/2008 Physician United Kingdom
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 58 Female 10/15/2008 Other Health Professional Japan
Primary
Secondary

Drug Data