Enalapril combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hyperaldosteronism Hospitalization 12/28/2004 73 Female 121 lb 2/3/2006 Consumer France
Primary
Secondary
Concomitant
Vomiting Other Serious 70 Male 2/7/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious Female 6/9/2006
Primary
Secondary
Syncope Hospitalization 4/17/2006 70 Male 6/12/2006 Physician United States
Primary
Secondary
Concomitant
Sedation 2/1/2006 83 Male 9/6/2006 Consumer United States
Primary
Concomitant
Syncope Required Intervention 76 Male 4/4/2007 Germany
Primary
Secondary
Concomitant
Vascular Pseudoaneurysm Hospitalization 2/1/2007 63 Male 185 lb 4/23/2007 Physician United States
Primary
Concomitant
Hyperhidrosis Life Threatening 4/30/2007 36 Male 326 lb 5/3/2007 Consumer United States
Primary
Concomitant
Suicidal Ideation Life Threatening 4/1/2007 65 Male 5/9/2007 Consumer United Kingdom
Primary
Concomitant
Vascular Pseudoaneurysm Hospitalization 2/1/2007 63 Male 185 lb 5/10/2007 Physician United States
Primary
Concomitant
Palpitations Other Serious 8/1/2006 38 Female 5/10/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Hospitalization 10 Female 5/14/2007
Primary
Concomitant
Vomiting Hospitalization 15 Male 93 lb 5/14/2007
Primary
Concomitant
Vomiting Hospitalization 15 Male 93 lb 6/15/2007 United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 5/29/2007 37 Male 292 lb 6/18/2007 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Other Serious 8/1/2006 84 Female 129 lb 6/28/2007 Consumer United States
Primary
Secondary
Visual Field Defect Other Serious 6/10/2007 52 Female 170 lb 8/16/2007 Consumer United States
Primary
Concomitant
Hepatitis C Other Serious 2/7/2002 Male 209 lb 8/16/2007 Consumer Japan
Primary
Concomitant
Hypotension Hospitalization 7/6/2007 50 Male 9/4/2007 Other Health Professional Philippines
Primary
Secondary
Concomitant
Sick Sinus Syndrome Life Threatening 2/21/2007 Female 103 lb 11/29/2007 Physician Japan
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2007 56 Female 137 lb 12/3/2007 Consumer United States
Primary
Concomitant
Interacting
X-ray Abnormal Other Serious 11/6/2007 50 Male 12/7/2007 Physician Canada
Primary
Concomitant
Syncope Other Serious 1/1/2007 91 Male 1/30/2008 Netherlands
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 1/12/2000 52 Male 4/18/2008 Pharmacist Canada
Primary
Concomitant
Urinary Tract Infection Life Threatening 9/4/2007 81 Male 174 lb 12/1/2007 Pharmacist United States
Primary
Secondary
Pneumonia Death 8/12/2007 88 Male 103 lb 7/28/2008 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 10/28/2008 2/6/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 1/11/2009 75 Female 2/20/2009 Physician Switzerland
Primary
Concomitant
Interacting
Product Quality Issue Other Serious 1/1/2009 71 Male 2/24/2009 South Africa
Primary
Concomitant
Hypoglycaemia Hospitalization 1/11/2009 75 Female 3/3/2009 Physician Switzerland
Primary
Concomitant
Interacting
Therapeutic Response Unexpected With Drug Substitution Other Serious 1/1/2009 71 Male 3/4/2009 South Africa
Primary
Concomitant
Oedema Peripheral 12/5/2008 69 Female 168 lb 3/16/2009 Consumer United States
Primary
Concomitant
Respiratory Rate Increased 11/22/2004 Female 3/16/2009 Consumer
Primary
Concomitant
Hypoglycaemia Life Threatening 12/14/2008 85 Female 154 lb 4/2/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 12/14/2008 85 Female 4/3/2009 Consumer Germany
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 12/14/2008 85 Female 4/9/2009 Consumer Germany
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/15/2004 49 Male 276 lb 4/21/2009 United States
Primary
Concomitant
Suicidal Ideation Other Serious 7/29/2003 43 Male 249 lb 4/21/2009 United States
Primary
Concomitant
Haemoglobin Decreased Male 4/21/2009 Pharmacist United States
Primary
Concomitant
Delirium 6/1/2007 61 Male 169 lb 12/22/2008 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Death 3/13/2009 Male 4/21/2009 Pharmacist Colombia
Primary
Secondary
Ventricular Fibrillation Hospitalization 3/13/2009 49 Male 4/23/2009 Pharmacist Colombia
Primary
Secondary
Oral Pain 3/25/2009 73 Female 139 lb 4/30/2009 Consumer United States
Primary
Concomitant
Shock Hospitalization 2/18/2009 82 Female 5/18/2009 Physician Switzerland
Primary
Secondary
Concomitant
Stress Other Serious 3/12/2004 44 Male 350 lb 5/20/2009 United States
Primary
Concomitant
Skin Neoplasm Excision Other Serious 58 Female 190 lb 5/20/2009 Consumer Brazil
Primary
Concomitant
Thrombosis Life Threatening 4/26/2009 97 5/28/2009 Consumer Peru
Primary
Concomitant
Weight Decreased Other Serious 76 Male 5/26/2009 Lawyer United States
Primary
Concomitant
Hyperkalaemia Life Threatening 8/20/2008 71 Female 176 lb 6/5/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 11/21/2008 70 Female 148 lb 6/11/2009 Physician Germany
Primary
Concomitant
Vomiting Death 54 Female 148 lb 6/23/2009 Lawyer United States
Primary
Concomitant
Myositis Other Serious 3/7/2009 Female 124 lb 7/13/2009 Physician United Kingdom
Primary
Concomitant
Haematuria Hospitalization 1/1/2009 78 8/20/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 80 Male 10/18/2009 Lawyer United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 10/22/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 10/26/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 90 Female 10/26/2009 United States
Primary
Concomitant
Heart Rate Increased 11/1/2008 75 Female 11/13/2009 Consumer United States
Primary
Concomitant
Asthma 8/26/2009 64 Female 10/20/2009 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 90 Female 11/18/2009 United States
Primary
Concomitant
Photodermatosis Hospitalization 72 Male 11/18/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 80 Female 11/20/2009 Lawyer United States
Primary
Concomitant
Blood Pressure Increased Other Serious 11/22/2009 Male 12/4/2009 Consumer Germany
Primary
Concomitant
Somnolence Hospitalization 1/1/2005 Female 173 lb 12/11/2009 Consumer United States
Primary
Concomitant
Photodermatosis Hospitalization 57 Male 12/10/2009 United States
Primary
Concomitant
Headache Other Serious 11/21/2009 Male 12/29/2009 Physician Germany
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 0 Male 2/3/2010 Physician India
Primary
Secondary
Unresponsive To Stimuli Other Serious 12/14/2008 85 Female 2/4/2010 Consumer Germany
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 12/14/2008 85 Female 154 lb 2/5/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Increased Hospitalization 66 Female 234 lb 5/6/2010 United States
Primary
Concomitant
Skin Discolouration Hospitalization 5/6/2010 73 Male 170 lb 5/25/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 5/13/2010 75 Female 6/2/2010 Consumer
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Linear Iga Disease Hospitalization 4/6/2010 87 Female 6/4/2010 Consumer Switzerland
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 4/28/2010 78 Male 134 lb 6/4/2010 Physician Japan
Primary
Concomitant
Hyperkalaemia Life Threatening 8/20/2008 71 Female 176 lb 6/11/2010 Physician Germany
Primary
Concomitant
Interacting
Wound Hospitalization Male 190 lb 6/11/2010 Consumer Brazil
Primary
Concomitant
Fluid Retention Hospitalization 1/1/2010 64 Female 8/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Cardio-respiratory Arrest Death 6/28/2010 58 Male 8/11/2010 Other Health Professional Colombia
Primary
Concomitant
Vomiting Other Serious 6/14/2004 58 Female 155 lb 8/24/2010 United States
Primary
Secondary
Concomitant
Hypotension Male 260 lb 8/28/2010 United States
Primary
Concomitant
Flushing 2/1/2010 71 Male 200 lb 8/29/2010 Consumer United States
Primary
Concomitant
Gout Female 155 lb 8/29/2010 Consumer United States
Primary
Concomitant
Rash Papular 5/1/2010 69 Female 158 lb 8/29/2010 Consumer United States
Primary
Concomitant
Blood Pressure Decreased Other Serious 90 Male 9/3/2010 Consumer Sweden
Primary
Secondary
Concomitant
Pharyngeal Oedema Other Serious 3/1/2008 50 Male 328 lb 9/15/2010 Physician United States
Primary
Concomitant
Vomiting Other Serious 6/14/2004 58 Female 155 lb 9/23/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/12/2010 63 Male 198 lb 10/18/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 9/12/2010 63 Male 198 lb 10/25/2010 Other Health Professional United Kingdom
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Tachycardia Death 11/21/2008 66 Female 143 lb 11/30/2010 Physician Netherlands
Primary
Concomitant
Productive Cough Death 10/1/2006 12/6/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 15 Male 11/17/2010 United States
Primary
Concomitant
Transplant Rejection Hospitalization 11/22/2010 66 Female 201 lb 12/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 8/6/2008 86 Female 12/10/2010 Other Health Professional Germany
Primary
Concomitant
Vomiting Other Serious 6/14/2004 58 Female 155 lb 12/13/2010 United States
Primary
Secondary
Concomitant
Death Death 12/15/2010 Physician Spain
Primary
Secondary
Concomitant
Skin Haemorrhage Other Serious 1/1/1999 60 Male 190 lb 12/20/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/13/2008 26 Male 137 lb 12/21/2010 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 61 Male 12/22/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 84 Female 12/14/2010 United States
Primary
Concomitant
Renal Impairment Death 1/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Pressure Decreased Other Serious 61 Male 1/3/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 9/1/2010 56 Male 212 lb 1/4/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Large Intestine Carcinoma Hospitalization 10/1/2010 Male 148 lb 1/4/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 1/5/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Death Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Palpitations Other Serious 3/1/2008 50 Male 328 lb 1/20/2011 Physician United States
Primary
Concomitant
Pupillary Reflex Impaired Life Threatening 1/13/2011 28 Female 1/21/2011 Physician China
Primary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 1/24/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Drug Interaction Death 1/25/2011 Consumer Japan
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 1/25/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Product Quality Issue Other Serious 75 Female 1/26/2011 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 10/1/2010 Male 148 lb 1/26/2011 Physician Japan
Primary
Secondary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 2/7/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 80 Female 1/26/2011 United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 80 Male 1/28/2011 United States
Primary
Concomitant
Insomnia 2/1/2011 Female 2/25/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 11/25/2010 79 Male 3/1/2011 Physician Italy
Primary
Concomitant
Insomnia 2/1/2011 Female 3/2/2011 Consumer United States
Primary
Concomitant
Hyperkalaemia Hospitalization 61 Male 3/11/2011 Other Health Professional Netherlands
Primary
Concomitant
Constipation Other Serious 6/14/2004 58 Female 155 lb 3/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 61 Male 3/23/2011 Other Health Professional Netherlands
Primary
Concomitant
Coronary Artery Disease Hospitalization 82 Male 3/30/2011 United States
Primary
Concomitant
Proteinuria Other Serious 4/26/2010 32 Female 154 lb 4/15/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Arrhythmia Other Serious 12/1/2007 54 Male 163 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 61 Male 3/31/2011 Consumer United States
Primary
Concomitant
Melaena Death 4/13/2008 26 Male 137 lb 4/26/2011 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 3/22/2011 78 Female 5/5/2011 Physician Colombia
Primary
Concomitant
Asthma Hospitalization 4/21/2011 75 Female 5/6/2011 Consumer United States
Primary
Secondary
Concomitant
Fear Of Death Other Serious 5/21/2003 56 Male 200 lb 5/9/2011 Lawyer United States
Primary
Concomitant
Cardiac Failure Other Serious 1/1/2011 57 Female 90 lb 5/13/2011 Consumer Brazil
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 1/1/2011 72 Male 5/13/2011 Physician Germany
Primary
Concomitant
Asthenia Death 11/19/2010 72 Male 5/23/2011 Other Health Professional Colombia
Primary
Concomitant
Constipation Other Serious 61 Female 7/28/2011 Other Health Professional Italy
Primary
Secondary
Concomitant
Somnolence 9/1/2011 35 Female 185 lb 9/20/2011 Consumer United States
Primary
Concomitant
Blood Creatinine Increased Other Serious 12/1/2010 21 Male 10/28/2011 Physician Brazil
Primary
Secondary
Pain Other Serious 2/1/2001 59 Female 143 lb 10/28/2011 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Hospitalization 6/14/2004 58 Female 155 lb 11/1/2011 Physician United States
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Hospitalization 10/21/2011 8 Female 11/1/2011 Physician Colombia
Primary
Concomitant
Cardiac Failure Hospitalization 1/1/2011 57 Female 90 lb 11/2/2011 Consumer Brazil
Primary
Secondary
Concomitant
Renal Failure Hospitalization 91 Female 11/9/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Acute Prerenal Failure Hospitalization 76 Male 12/19/2011 Physician Japan
Primary
Secondary
Concomitant
Hypercalcaemia Hospitalization 91 Female 12/19/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cardiomegaly Hospitalization 1/1/2011 57 Female 90 lb 12/30/2011 Consumer Brazil
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 9/15/2009 69 Male 185 lb 1/27/2012 Physician Israel
Primary
Secondary
Concomitant
Nausea Hospitalization 8/31/2011 1/31/2012 Pharmacist United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 9/17/2011 71 Female 2/14/2012 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Disability 12/14/2011 51 Male 152 lb 2/17/2012 Physician United States
Primary
Secondary
Concomitant

Drug Data