Enalapril Maleate combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombosis Hospitalization 1/20/2001 Male 1/3/2006 France
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization Female 1/4/2006 United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 72 Female 1/4/2006 United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 72 Female 1/5/2006 Physician United States
Primary
Secondary
Gynaecomastia Hospitalization 8/15/2004 70 Male 1/19/2006 Physician Sweden
Primary
Concomitant
Abdominal Haematoma Life Threatening 12/6/2005 81 Female 1/23/2006 Norway
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 9/20/2004 86 Male 1/31/2006 Consumer Australia
Primary
Secondary
Concomitant
Thermal Burn 10/2/2005 Male 12/7/2005 United States
Primary
Concomitant
Sinus Arrest Hospitalization 7/10/2004 53 Male 143 lb 2/2/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 89 Male 2/16/2006 United Kingdom
Primary
Concomitant
Sepsis Hospitalization 9/16/2005 87 Female 145 lb 11/28/2005 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 4/1/2004 60 Male 3/17/2006 Consumer Brazil
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 1/11/2006 79 Female 106 lb 3/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/31/2005 58 Male 186 lb 4/11/2006 United States
Primary
Concomitant
Respiratory Failure Death 3/14/2006 62 Female 4/6/2006 Pharmacist South Africa
Primary
Concomitant
Vomiting Other Serious 3/22/2006 84 Male 5/1/2006 Germany
Primary
Concomitant
Nervous System Disorder Other Serious 12/5/2005 59 Male 4/25/2006 Sweden
Primary
Concomitant
Vomiting Other Serious 4/1/2002 70 Male 4/27/2006 Canada
Primary
Secondary
Concomitant
Dyspnoea 1/26/2006 70 Female 2/21/2006 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 1/11/2006 79 Female 106 lb 3/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 4/12/2006 56 Male 132 lb 4/28/2006 Japan
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/22/2006 81 Male 162 lb 5/8/2006
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Hospitalization 3/13/2006 83 Male 5/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 4/1/2006 86 Female 160 lb 5/8/2006 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 3/22/2006 81 Male 162 lb 5/9/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 76 Male 5/19/2006 Other Health Professional Japan
Primary
Concomitant
Interacting
Pulmonary Oedema Hospitalization 2/22/2006 74 Male 225 lb 6/23/2006 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Death 4/10/2006 85 Male 6/27/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Dyspnoea 1/27/2006 70 Female 5/19/2006 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/27/2006 61 Male Pharmacist United States
Primary
Concomitant
Haematemesis Hospitalization 6/14/2006 72 Male 123 lb 7/7/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/20/2006 43 Male 7/25/2006 Physician Belarus
Primary
Concomitant
Pulmonary Arterial Pressure Increased Other Serious 3/31/2005 12 Female 68 lb 7/24/2006 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 6/1/2006 71 Female 85 lb 7/31/2006 Physician Japan
Primary
Concomitant
Pain Other Serious 4/1/2003 78 Female 140 lb 7/5/2006 United States
Primary
Concomitant
Vomiting Other Serious 20 Female 8/9/2006 Physician Israel
Primary
Secondary
Concomitant
Vomiting Hospitalization 20 Female 8/9/2006 Other Health Professional Israel
Primary
Secondary
Unevaluable Event Hospitalization 8/17/2006 80 Female 8/28/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Respiratory Disorder Other Serious 6/1/2006 71 Female 85 lb 8/24/2006 Physician Japan
Primary
Concomitant
Hyperkalaemia Hospitalization 6/20/2006 70 Male 9/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 9/7/2006 74 Male 121 lb 9/21/2006 Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 9/7/2006 74 Male 121 lb 10/3/2006 Physician Japan
Primary
Concomitant
Hypoglycaemia Other Serious 71 Female 10/10/2006 Other Health Professional Canada
Primary
Concomitant
Palpitations Hospitalization 2/11/2006 82 Female 127 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 68 Male 10/11/2006 Other Health Professional United States
Primary
Concomitant
Troponin Increased Death 7/3/2006 77 Male 170 lb 8/25/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 8/18/2006 68 Female 110 lb 9/22/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 9/1/2006 72 Female 158 lb 10/17/2006 United States
Primary
Concomitant
Dyspnoea 1/27/2006 70 Female 8/22/2006 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 7/19/2006 73 Male 118 lb 7/24/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 2/14/2006 84 Male 97 lb 11/2/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/5/2006 91 Female 11/3/2006 Sweden
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 63 Male 11/10/2006 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 9/7/2006 74 Male 121 lb 11/9/2006 Physician Japan
Primary
Concomitant
Intra-abdominal Haemorrhage Other Serious 8/15/2006 Female 185 lb 11/22/2006 Physician Czech Republic
Primary
Concomitant
Varicose Ulceration Other Serious 8/15/2006 Female 198 lb 11/22/2006 Physician Czech Republic
Primary
Concomitant
Urinary Tract Infection Other Serious 2/14/2006 84 Male 97 lb 11/17/2006 Physician Japan
Primary
Secondary
Concomitant
Cholecystitis Acute Hospitalization 10/20/2006 80 Female 11/23/2006 Physician Italy
Primary
Concomitant
Renal Impairment Other Serious 6/21/2006 77 Female 128 lb 12/6/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Arterial Pressure Increased 12 Female 68 lb 11/30/2006 Physician Japan
Primary
Concomitant
Off Label Use Hospitalization 12/12/2005 53 Female 84 lb 11/30/2006 Physician Japan
Primary
Concomitant
Visual Disturbance Other Serious 7/1/2006 80 Male 12/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myoclonus Other Serious 55 Male 12/13/2006 Pharmacist United States
Primary
Concomitant
Somnolence Required Intervention 75 Female 12/14/2006 Physician Norway
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious 7/1/2006 69 Male 182 lb 1/2/2007 Other Health Professional United Kingdom
Primary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 63 Male 12/20/2006 Physician Japan
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2006 Female 222 lb 1/5/2007 Physician United States
Primary
Secondary
Concomitant
Subdural Haematoma Required Intervention 8/4/2006 83 Male 181 lb 10/2/2006 United States
Primary
Concomitant
Lactic Acidosis Other Serious 75 Female 1/29/2007 Other Health Professional Norway
Primary
Secondary
Concomitant
Somnolence Life Threatening 75 Female 1/25/2007 Other Health Professional Norway
Primary
Secondary
Concomitant
Somnolence Hospitalization 75 Female 1/22/2007 Norway
Primary
Secondary
Concomitant
Inflammation Other Serious 1/6/2007 Male 126 lb 2/6/2007 Physician Japan
Primary
Secondary
Concomitant
Lactic Acidosis Other Serious 75 Female 2/6/2007 Other Health Professional Norway
Primary
Secondary
Concomitant
Tremor Other Serious 3/1/2006 66 Male 270 lb 8/17/2006 United States
Primary
Concomitant
Inflammation Other Serious 1/6/2007 Male 126 lb 2/14/2007 Physician Japan
Primary
Secondary
Concomitant
Swelling 54 Female 180 lb 2/14/2007 Pharmacist United States
Primary
Concomitant
Cataract Subcapsular Disability 6/1/2004 Female 144 lb 2/15/2007 Singapore
Primary
Concomitant
Skin Cancer Other Serious 2/1/2006 Female 230 lb 3/1/2007 Physician United States
Primary
Concomitant
Neurological Symptom Other Serious 9/27/2005 Male 251 lb 3/12/2007 Physician United States
Primary
Concomitant
Somnolence Hospitalization 75 Female 3/20/2007 Norway
Primary
Concomitant
Melaena Hospitalization 1/22/2007 61 Male 3/28/2007 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/8/2007 52 Male 3/28/2007 Pharmacist United States
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 7/1/2006 69 Male 182 lb 4/5/2007 Consumer United Kingdom
Primary
Concomitant
Overdose Hospitalization 3/13/2007 74 Male 4/20/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Weight Decreased Required Intervention 68 Male 5/4/2007 Other Health Professional United States
Primary
Concomitant
Rectal Haemorrhage Life Threatening 3/14/2007 79 Male 5/8/2007 Pharmacist United States
Primary
Concomitant
Flat Affect Hospitalization 5/4/2006 77 Female 12/13/2006 United States
Primary
Concomitant
Prostatic Disorder Hospitalization 5/19/2006 68 Male 6/12/2007 United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 69 Female 6/26/2007 Italy
Primary
Secondary
Toxic Epidermal Necrolysis Death 69 Female 7/10/2007
Primary
Secondary
Toxic Epidermal Necrolysis Death 69 Female 7/12/2007
Primary
Secondary
Sudden Cardiac Death Death 12/3/2005 30 Male 1/13/2006 Physician United States
Primary
Concomitant
Oedema Peripheral 7/23/2007 Consumer United States
Primary
Concomitant
Nasal Congestion Hospitalization 4/27/2007 63 Female 287 lb 7/17/2007 Physician United Kingdom
Primary
Concomitant
Epistaxis Hospitalization 4/27/2007 63 Female 287 lb 7/17/2007 Physician United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 69 Female 7/25/2007 Italy
Primary
Secondary
Prostatic Disorder Hospitalization 3/1/2006 67 Male 7/30/2007 United Kingdom
Primary
Concomitant
Encephalopathy Life Threatening 6/2/2007 73 Male 7/31/2007 Other Health Professional Japan
Primary
Concomitant
Gun Shot Wound Death 7/11/2007 73 Male 7/31/2007 Other Health Professional Finland
Primary
Concomitant
Prostatic Disorder Hospitalization 3/1/2006 67 Male 8/7/2007 United Kingdom
Primary
Concomitant
Somnolence Other Serious 1/1/2006 Female 159 lb 8/7/2007 Consumer United States
Primary
Secondary
Concomitant
Rash Hospitalization 6/8/2006 88 Male 8/6/2007 Pharmacist United States
Primary
Concomitant
Injection Site Haemorrhage 4/30/2007 73 Male 7/11/2007 Consumer United States
Primary
Concomitant
Repetitive Strain Injury Other Serious 1/1/2006 70 Female 9/11/2007 Consumer United States
Primary
Concomitant
Cholecystitis Acute Hospitalization 10/20/2006 Female 10/17/2007 Physician Italy
Primary
Concomitant
Platelet Count Decreased Required Intervention 8/23/2007 43 Female 104 lb 10/4/2007 United States
Primary
Concomitant
Initial Insomnia 6/27/2007 93 Male 137 lb 10/5/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint 78 Female 10/24/2007 Consumer United States
Primary
Concomitant
Cardiomyopathy Other Serious 56 Male 10/26/2007 Other Health Professional Australia
Primary
Concomitant
Drug Ineffective Death 9/3/2007 63 Male 10/17/2007 Japan
Primary
Concomitant
Hypotension Death 9/3/2007 63 Male 10/17/2007 Japan
Primary
Concomitant
Drug Ineffective Other Serious 10/2/2007 Female 107 lb 11/1/2007 Physician Japan
Primary
Secondary
Concomitant
Cough Other Serious 6/29/2007 Male 11/9/2007 Consumer Brazil
Primary
Concomitant
Rash Generalised Disability 11/1/2005 Female 201 lb 11/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pain In Extremity 1/22/2007 88 Female 11/13/2007 Consumer United States
Primary
Concomitant
Toothache Disability 11/1/2005 11/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rash Generalised Disability 11/1/2005 79 Female 201 lb 11/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective Other Serious 10/2/2007 Female 107 lb 11/21/2007 Physician Japan
Primary
Secondary
Concomitant
Melaena Hospitalization 11/16/2006 77 Male 139 lb 11/23/2007 Physician Japan
Primary
Concomitant
Fatigue Hospitalization 11/18/2007 Male 159 lb 12/3/2007 Physician Sweden
Primary
Concomitant
Renal Failure Acute Hospitalization 11/22/2007 81 Male 12/14/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/22/2007 81 Male 12/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 1/25/2007 71 Male 1/4/2008 Physician Japan
Primary
Secondary
Liver Disorder Hospitalization 1/25/2007 71 Male 1/8/2008 Physician Japan
Primary
Secondary
Renal Failure Acute Hospitalization 11/22/2007 81 Male 12/28/2007 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 12/18/2007 69 Male 119 lb 1/15/2008 Physician Japan
Primary
Concomitant
Interacting
Renal Haemorrhage Other Serious 72 Male 170 lb 1/24/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 12/18/2007 69 Male 119 lb 1/30/2008 Physician Japan
Primary
Concomitant
Interacting
Pulmonary Embolism Death 8/19/2007 29 Female 12/18/2007 Pharmacist United States
Primary
Secondary
Concomitant
Subdural Haematoma Disability 74 Female 2/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 10/7/2007 80 Male 136 lb 2/22/2008 Consumer Brazil
Primary
Concomitant
Pulmonary Hypertension Death 10/7/2007 80 Male 132 lb 2/27/2008 Consumer Brazil
Primary
Concomitant
Post Procedural Complication Hospitalization 1/28/2008 86 Female 189 lb 2/22/2008 Other Health Professional United States
Primary
Concomitant
Bone Marrow Failure Hospitalization Male 121 lb 2/29/2008 Physician Japan
Primary
Concomitant
Hallucination Other Serious 2/21/2008 71 Male 3/4/2008 Physician Japan
Primary
Concomitant
Psychiatric Symptom Other Serious 2/21/2008 71 Male 150 lb 3/6/2008 Pharmacist Japan
Primary
Concomitant
Weight Increased Other Serious 12/1/2007 Female 3/7/2008 Consumer United States
Primary
Concomitant
Prothrombin Level Decreased Other Serious 12/14/2007 Male 3/10/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Anaemia Hospitalization 3/3/2008 73 Female 3/11/2008 Physician Japan
Primary
Concomitant
Cystitis Disability 3/3/2007 82 Female 3/12/2008 Other Health Professional Japan
Primary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 2/6/2008 71 Male 183 lb 3/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Psychiatric Symptom Other Serious 2/21/2008 71 Male 150 lb 3/20/2008 Pharmacist Japan
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/13/2007 82 Male 3/4/2008 Sweden
Primary
Secondary
Concomitant
Anaemia Hospitalization 3/3/2008 73 Female 3/28/2008 Physician Japan
Primary
Concomitant
Psychiatric Symptom Other Serious 2/21/2008 71 Male 150 lb 4/1/2008 Pharmacist Japan
Primary
Concomitant
Subdural Haematoma Disability Female 3/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Failure Hospitalization 1/29/2008 Male 121 lb 4/3/2008 Physician Japan
Primary
Concomitant
Heart Rate Irregular Hospitalization 3/1/2008 Female 4/3/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Death 12/16/2007 37 Male 138 lb 4/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Anaemia Hospitalization 3/3/2008 73 Female 4/15/2008 Physician Japan
Primary
Concomitant

Drug Data