Enalapril Maleate combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sarcoma Hospitalization 1/1/2003 Male 1/18/2006 United States
Primary
Concomitant
Gynaecomastia Hospitalization 8/15/2004 70 Male 1/19/2006 Physician Sweden
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 78 Female 1/19/2006 Physician Greece
Primary
Secondary
Renal Failure Acute Hospitalization 89 Male 2/16/2006 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/4/2005 87 Female 108 lb 1/23/2006 Pharmacist United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 2/14/2006 47 Male 150 lb 2/22/2006 United States
Primary
Concomitant
Vomiting Hospitalization 56 Male 3/6/2006 Physician Israel
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 3/3/2006 64 Female 225 lb 3/14/2006 Consumer United States
Primary
Concomitant
Ventricular Extrasystoles 1/19/2006 77 Male 3/9/2006 Japan
Primary
Concomitant
Odynophagia Hospitalization 1/15/2006 71 Male 3/10/2006 Physician Japan
Primary
Secondary
Condition Aggravated Other Serious 52 Female 3/16/2006 Physician France
Primary
Secondary
Concomitant
Angioneurotic Oedema Hospitalization 1/15/2006 71 Male 3/17/2006 Physician Japan
Primary
Secondary
Pharmaceutical Product Complaint Other Serious 2/14/2006 47 Male 150 lb 3/24/2006 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 7/1/2005 Male 154 lb 3/31/2006 Physician Germany
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 1 Female 4/1/2006 Other Health Professional Canada
Primary
Secondary
Ventricular Extrasystoles Other Serious 1/19/2006 77 Male 3/29/2006 Japan
Primary
Concomitant
Hepatic Cirrhosis Hospitalization 7/1/2005 46 Male 225 lb 3/28/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/15/2006 71 Male 4/3/2006 Physician Japan
Primary
Secondary
Ventricular Hypertrophy Other Serious 1 Female 4/10/2006 Canada
Primary
Secondary
Blood Glucose Increased Hospitalization 3/3/2006 64 Female 225 lb 4/24/2006 Consumer United States
Primary
Concomitant
Methaemoglobinaemia Life Threatening 6/20/2005 17 Female 117 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Osteonecrosis Other Serious 7/1/2002 63 Male 5/1/2006 Physician Sweden
Primary
Secondary
Concomitant
Vomiting Other Serious 4/1/2002 70 Male 4/27/2006 Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 4/12/2006 56 Male 132 lb 4/28/2006 Japan
Primary
Concomitant
Pain In Extremity Hospitalization 3/3/2006 64 Female 225 lb 5/10/2006 Consumer United States
Primary
Concomitant
Pancytopenia Hospitalization 7/13/2005 80 Male 5/26/2006 Physician Germany
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 1/1/2005 88 Female 194 lb 6/5/2006 Pharmacist Spain
Primary
Secondary
Weight Decreased Hospitalization 7/9/2005 80 Male 6/7/2006 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/24/2006 52 Female 6/16/2006 Physician France
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Death 4/10/2006 85 Male 6/27/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Tremor Hospitalization 5/25/2006 63 Male 237 lb 5/26/2006 Pharmacist United States
Primary
Secondary
Ascites Other Serious 5/23/2006 34 Female 141 lb 7/31/2006 Physician Poland
Primary
Concomitant
Feeling Cold 80 Female 164 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Ascites Other Serious 5/23/2006 34 Female 141 lb 9/6/2006 Physician Poland
Primary
Concomitant
Ventricular Hypertrophy Other Serious Female 9/6/2006 Canada
Primary
Concomitant
Hyperkalaemia Hospitalization 6/20/2006 70 Male 9/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 10/13/2000 6 Female 53 lb 9/14/2006 Physician Canada
Primary
Secondary
Ventricular Hypertrophy Other Serious 10/13/2000 6 Female 53 lb 9/14/2006 Physician Canada
Primary
Secondary
Ascites Other Serious 5/23/2006 34 Female 119 lb 9/18/2006 Physician Poland
Primary
Concomitant
Renal Failure Acute Hospitalization 7/1/2006 70 Female 10/3/2006 Physician France
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 8/1/2006 57 Male 10/13/2006 Physician France
Primary
Secondary
Concomitant
Feeling Cold 11/22/2004 74 Female 8/22/2006 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/2/2006 65 Male 11/1/2006 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/5/2006 91 Female 11/3/2006 Sweden
Primary
Secondary
Concomitant
Vomiting Projectile Other Serious 10/20/2006 81 Female 172 lb 11/9/2006 Pharmacist United States
Primary
Concomitant
Malaise Hospitalization 5/28/2005 94 Female 11/13/2006 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/22/2006 83 Female 11/10/2006 Physician France
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 10/10/2006 2 Female 18 lb 11/20/2006 Physician Greece
Primary
Concomitant
Malaise Hospitalization 5/28/2006 94 Female 11/21/2006 Physician France
Primary
Secondary
Concomitant
Drug Interaction Other Serious 9/15/2006 70 Male 12/1/2006 Other Health Professional France
Primary
Concomitant
Interacting
Hyponatraemia Hospitalization 7/11/2005 83 Female 11/22/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Drug Interaction Other Serious 9/15/2006 70 Male 12/14/2006 Physician Denmark
Primary
Concomitant
Interacting
Respiratory Failure Hospitalization 11/18/2006 62 Male 187 lb 12/18/2006 Physician Spain
Primary
Secondary
Blood Creatinine Increased Hospitalization 11/30/2005 85 Female 1/3/2007 Other Health Professional Sweden
Primary
Concomitant
Urine Output Decreased Hospitalization 11/18/2006 62 Male 187 lb 1/3/2007 Physician Spain
Primary
Secondary
Weight Decreased Life Threatening 10/10/2006 2 Female 18 lb 1/4/2007 Physician Greece
Primary
Secondary
Concomitant
Pleural Disorder Hospitalization 12/1/2006 72 Female 1/19/2007 Consumer United States
Primary
Concomitant
Weight Decreased Life Threatening 10/10/2006 2 Female 18 lb 1/17/2007 Physician Greece
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/6/2006 Male 145 lb 2/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 10/10/2006 2 Female 18 lb 1/31/2007 Physician Greece
Primary
Secondary
Concomitant
Hypertension Life Threatening 1/8/2007 Female 2/12/2007 Physician Bulgaria
Primary
Concomitant
Ascites Other Serious 5/23/2006 Female 119 lb 2/14/2007 Poland
Primary
Concomitant
Vomiting Hospitalization 3/16/2006 Male 198 lb 2/23/2007 Other Health Professional United Kingdom
Primary
Concomitant
Blood Glucose Increased Other Serious 71 Female 2/27/2007 United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 11/24/2006 Female 139 lb 3/5/2007 Physician Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 12/2/2006 60 Male 3/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 11/24/2006 Female 139 lb 3/9/2007 Physician Japan
Primary
Concomitant
Septic Shock Hospitalization 11/18/2006 62 NotSpecified 187 lb 3/6/2007 Physician Spain
Primary
Secondary
Hyperglycaemia Other Serious 75 Female 135 lb 4/8/2005 United States
Primary
Concomitant
Hyperglycaemia Other Serious 75 Female 135 lb 4/8/2005 United States
Primary
Concomitant
Hyperglycaemia Other Serious Female 4/16/2004 United States
Primary
Concomitant
Hypertension Life Threatening 1/8/2007 Female 3/16/2007 Physician Bulgaria
Primary
Concomitant
Myocardial Infarction Hospitalization 2/1/2007 63 Male 4/2/2007 Physician United States
Primary
Concomitant
Hypertension Life Threatening 1/8/2007 Female 4/6/2007 Physician Bulgaria
Primary
Concomitant
Weight Decreased Life Threatening 10/10/2006 2 Female 18 lb 3/29/2007 Physician Greece
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 2/15/2007 71 Female 161 lb 4/5/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/27/2006 72 Male 5/2/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Myalgia Other Serious 4/13/2007 68 Male 181 lb 5/8/2007 Physician Germany
Primary
Secondary
Concomitant
Musculoskeletal Stiffness Life Threatening 4/23/2007 83 Female 5/15/2007 Finland
Primary
Concomitant
Hyperhidrosis Life Threatening 4/30/2007 36 Male 326 lb 5/30/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Death 3/14/2007 79 Female 5/24/2007 Sweden
Primary
Concomitant
Vomiting Other Serious 10 Female 5/18/2007 United States
Primary
Concomitant
Vomiting Hospitalization 15 Male 92 lb 5/18/2007 United States
Primary
Concomitant
Psoriasis Other Serious 5/1/2007 Female 132 lb 6/4/2007 Physician Colombia
Primary
Concomitant
Oedema Peripheral Other Serious 8/1/2006 84 Female 129 lb 6/15/2007 Consumer United States
Primary
Secondary
Oedema Peripheral Hospitalization 8/1/2006 84 Female 129 lb 7/11/2007 Consumer United States
Primary
Secondary
Hypertension Life Threatening 1/8/2007 Female 7/16/2007 Physician Bulgaria
Primary
Concomitant
Sarcoma Hospitalization 5/20/2003 Male 7/24/2007 United States
Primary
Concomitant
Peritonitis Life Threatening 10/7/2006 72 Female 78 lb 7/20/2007 Physician Japan
Primary
Secondary
Concomitant
Urticaria 39 Female 8/1/2007 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 12/17/2006 Female 8/8/2007 Physician United States
Primary
Concomitant
Hypotension Life Threatening 78 Female 8/9/2007 Other Health Professional France
Primary
Concomitant
Blood Pressure Decreased 5/5/2007 64 Male 8/3/2007 Consumer United States
Primary
Concomitant
Pneumonia Bacterial Hospitalization 12/17/2006 Female 8/15/2007 Physician United States
Primary
Concomitant
Large Intestine Perforation Life Threatening 10/7/2006 72 Female 78 lb 8/13/2007 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 78 Female 8/17/2007 Greece
Primary
Secondary
Peritonitis Life Threatening 10/7/2006 72 Female 78 lb 8/23/2007 Physician Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 64 Female 10/2/2007 Physician Italy
Primary
Concomitant
Oedema Peripheral Other Serious 8/1/2006 84 Female 130 lb 10/9/2007 United States
Primary
Secondary
Sick Sinus Syndrome Life Threatening 8/19/2007 Female 103 lb 10/24/2007 Physician Japan
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Hospitalization 6/15/2007 83 Female 10/30/2007 Italy
Primary
Secondary
Concomitant
Sick Sinus Syndrome Life Threatening 8/19/2007 83 Female 103 lb 10/25/2007 Physician Japan
Primary
Secondary
Concomitant
Sick Sinus Syndrome Life Threatening 2/21/2007 Female 103 lb 11/9/2007 Physician Japan
Primary
Secondary
Concomitant
Respiratory Syncytial Virus Infection Other Serious 5/8/2007 2 Male 10/31/2007 Physician Japan
Primary
Concomitant
Visual Disturbance 10/1/2006 68 Female 131 lb 11/13/2007 Consumer United States
Primary
Concomitant
Thyroid Disorder Hospitalization 4/1/2006 15 Female 11/13/2007 Physician Japan
Primary
Concomitant
Pulmonary Oedema Other Serious 6/10/2007 Male 200 lb 11/21/2007 United States
Primary
Concomitant
Sick Sinus Syndrome Life Threatening 8/19/2007 83 Female 103 lb 11/13/2007 Physician Japan
Primary
Secondary
Concomitant
Haemoconcentration Other Serious 8/16/2007 60 Male 11/16/2007 Russian Federation
Primary
Secondary
Palpitations 7/21/2007 73 Male 11/16/2007 United States
Primary
Concomitant
Sick Sinus Syndrome Life Threatening 8/15/2007 83 Female 103 lb 12/2/2007 Physician Japan
Primary
Secondary
Concomitant
In-stent Arterial Restenosis Hospitalization 4/8/2007 58 Male 176 lb 12/31/2007 Israel
Primary
Concomitant
Thyroid Disorder Hospitalization 4/1/2006 15 Female 1/8/2008 Physician Japan
Primary
Concomitant
Urinary Tract Infection Life Threatening 9/4/2007 81 Male 174 lb 1/7/2008 Pharmacist United States
Primary
Secondary
In-stent Coronary Artery Restenosis Hospitalization 4/8/2007 58 Male 176 lb 1/14/2008 Israel
Primary
Concomitant
Renal Failure Life Threatening 8/26/2007 Male 1/21/2008 Other Health Professional France
Primary
Concomitant
Viral Infection Hospitalization 12/3/2007 3/4/2008 Physician United States
Primary
Concomitant
Prothrombin Level Decreased Other Serious 12/14/2007 Male 3/10/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Viral Infection Hospitalization 12/3/2007 69 Male 3/11/2008 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 12/3/2007 69 Male 3/17/2008 Physician United States
Primary
Concomitant
Rash Disability 12/27/2007 Male 296 lb 3/25/2008 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 2/7/2008 Female 3/27/2008 Physician United States
Primary
Concomitant
Loss Of Consciousness Other Serious 68 Male 3/31/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Death 12/16/2007 37 Male 138 lb 4/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Retching Hospitalization 3/4/2008 65 Female 251 lb 4/17/2008 Pharmacist United States
Primary
Concomitant
Hypotension Other Serious 7/6/2007 Male 4/21/2008 Philippines
Primary
Secondary
Concomitant
Medication Error 10/1/2007 Male 4/19/2008 United States
Primary
Secondary
Cardiac Failure Congestive Hospitalization 3/2/2007 80 Male 150 lb 5/7/2008 Physician Japan
Primary
Concomitant
Disease Progression Hospitalization 3/11/2008 82 Male 150 lb 5/7/2008 Physician Japan
Primary
Concomitant
Vomiting Death 3/17/2008 70 Male 5/28/2008 United States
Primary
Concomitant
Renal Disorder Hospitalization 5/15/2008 71 Female 6/13/2008 Pharmacist Japan
Primary
Concomitant
Thyroid Function Test Abnormal Hospitalization 5/1/2008 Male 287 lb 6/13/2008 Physician United States
Primary
Concomitant
Interacting
Syncope Hospitalization 4/25/2008 55 Male 228 lb 6/19/2008 United States
Primary
Concomitant
Renal Failure Hospitalization Male 6/30/2008 Sweden
Primary
Concomitant
Renal Disorder Hospitalization 5/15/2008 71 Female 7/2/2008 Pharmacist Japan
Primary
Concomitant
Sepsis Death 2/21/2008 66 Female 7/7/2008 Physician United States
Primary
Concomitant
Left Ventricular Failure Hospitalization 8/26/1999 Female 7/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 7/15/2007 Female 8/6/2008 Physician Germany
Primary
Concomitant
Urinary Tract Infection Hospitalization 8/26/1999 Female 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 3/15/2008 8/12/2008 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 8/26/1999 Female 8/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Death 3/1/2007 83 Female 8/20/2008 Consumer United States
Primary
Concomitant
Hyperkalaemia Required Intervention 7/8/2008 74 Male 8/5/2008 Pharmacist United States
Primary
Secondary
Oropharyngeal Pain 81 Male 8/15/2008 United States
Primary
Concomitant
Vomiting Hospitalization 5/22/2008 78 Male 8/27/2008 Other Health Professional Spain
Primary
Concomitant
Respiratory Failure Hospitalization 77 Female 194 lb 9/4/2008 Consumer Brazil
Primary
Concomitant
Injection Site Pain Other Serious 10/29/2007 74 Male 9/5/2008 Japan
Primary
Concomitant
Tenderness Hospitalization 8/1/2008 Male 9/11/2008 United States
Primary
Concomitant
Tenderness Hospitalization 8/1/2008 Male 9/12/2008 United States
Primary
Concomitant
Swelling Death 4/1/2006 Female 135 lb 9/15/2008 Consumer United States
Primary
Secondary
Concomitant

Drug Data