Enalapril Maleate combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cholangitis Hospitalization 1/24/2000 Female 1/3/2006 Australia
Primary
Concomitant
Thrombosis Hospitalization 1/20/2001 Male 1/3/2006 France
Primary
Concomitant
Pulmonary Embolism Other Serious 9/15/2003 Male 1/4/2006 Australia
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 2/12/2002 Female 1/4/2006 Finland
Primary
Concomitant
Pulmonary Fibrosis Hospitalization 7/14/2004 Male 1/4/2006 France
Primary
Concomitant
Thrombosis Hospitalization 11/25/2002 Female 1/4/2006 France
Primary
Concomitant
Pituitary Tumour Benign Hospitalization 12/13/2001 Female 1/4/2006 Australia
Primary
Concomitant
Atrial Flutter Other Serious 8/2/2005 62 Male 3/3/2006 Other Health Professional Argentina
Primary
Secondary
Concomitant
Anaemia Other Serious 12/30/2005 46 Male 3/10/2006 Other Health Professional South Africa
Primary
Secondary
Concomitant
Prothrombin Time Shortened Hospitalization 1/8/2006 73 Female 3/30/2006 Other Health Professional Italy
Primary
Concomitant
Rhabdomyolysis Hospitalization 2/4/2006 Female 126 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 2/4/2006 66 Female 126 lb 4/6/2006 United States
Primary
Secondary
Concomitant
Prothrombin Time Shortened Hospitalization 1/8/2006 73 Female 4/24/2006 Other Health Professional Italy
Primary
Concomitant
Atrial Flutter Other Serious 8/2/2005 62 Male 4/27/2006 Other Health Professional Argentina
Primary
Secondary
Concomitant
Rash Hospitalization 5/15/2006 64 Male 284 lb 5/15/2006 Pharmacist United States
Primary
Concomitant
Granulocytopenia Required Intervention 10/10/2005 45 Female 1/27/2006 United States
Primary
Concomitant
Scrotal Pain Hospitalization 7/1/2006 68 Male 8/18/2006 Other Health Professional Hungary
Primary
Concomitant
Urinary Retention Hospitalization 10/24/2005 81 Male 9/7/2006 Other Health Professional Japan
Primary
Concomitant
Urinary Retention Hospitalization 10/24/2005 81 Male 10/10/2006 Other Health Professional Japan
Primary
Concomitant
Granulocytopenia Life Threatening 12/12/2006 67 Male 1/2/2007 Germany
Primary
Concomitant
Bradycardia Hospitalization 12/21/2006 70 Male 2/5/2007 Japan
Primary
Concomitant
Atrioventricular Block Second Degree Life Threatening 12/21/2006 72 Male 3/1/2007 Japan
Primary
Concomitant
Somnolence Hospitalization 75 Female 3/20/2007 Norway
Primary
Concomitant
Hypoglycaemia Other Serious 12/4/2006 58 Male 201 lb 4/26/2007 Physician United States
Primary
Concomitant
Hypotension Hospitalization 4/30/2007 75 Male 7/18/2007 Other Health Professional France
Primary
Concomitant
Interacting
Shock Required Intervention 73 Male 7/26/2007 Spain
Primary
Concomitant
Respiratory Disorder Hospitalization 6/17/2007 79 Male 8/28/2007 Physician France
Primary
Secondary
Concomitant
Metabolic Acidosis Life Threatening 1/1/2007 73 Female 9/19/2007 United Kingdom
Primary
Concomitant
Kidney Infection Hospitalization 9/1/2007 87 Female 9/26/2007 Consumer United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 5/19/2006 73 Male 280 lb 11/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 11/22/2007 81 Male 12/28/2007 United States
Primary
Secondary
Concomitant
Cholestasis Hospitalization 10/1/2007 78 Female 1/31/2008 Physician Germany
Primary
Concomitant
Bronchospasm Other Serious 2/23/2008 62 Male 3/7/2008 Physician Spain
Primary
Secondary
Concomitant
Peripheral Ischaemia Other Serious 2/12/2008 79 Female 4/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Death 55 Male 190 lb 8/27/2008 Other Health Professional Denmark
Primary
Concomitant
Bronchospasm Other Serious 2/23/2008 62 Male 10/14/2008 Physician Spain
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 8/5/2006 60 Male 185 lb 10/17/2008 Consumer United States
Primary
Concomitant
Hepatitis Toxic Other Serious 4/1/2006 50 Male 10/22/2008 Denmark
Primary
Concomitant
Osteoarthritis Hospitalization 9/25/2008 12/24/2008 Physician Brazil
Primary
Secondary
Concomitant
Osteoarthritis Hospitalization 9/25/2008 12/31/2008 Physician Brazil
Primary
Secondary
Concomitant
Nausea Hospitalization 11/26/2008 68 Male 1/3/2009 Japan
Primary
Concomitant
Somnolence Hospitalization 72 Male 1/21/2009 Other Health Professional Netherlands
Primary
Concomitant
Vomiting Other Serious 11/26/2000 Male 2/2/2009 Japan
Primary
Concomitant
Splenic Marginal Zone Lymphoma Hospitalization 75 Male 2/23/2009 Other Health Professional France
Primary
Concomitant
Renal Failure Acute Hospitalization 2/6/2009 75 Male 5/29/2009 Physician Switzerland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 Male 163 lb 7/17/2009 Physician United States
Primary
Concomitant
Tinnitus Hospitalization 51 Male 7/21/2009 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 12/8/2006 86 Female 8/20/2009 United States
Primary
Concomitant
Vision Blurred Disability 1/1/2009 65 Female 203 lb 8/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Disability 1/1/2009 65 Female 8/31/2009 United Kingdom
Primary
Concomitant
Gangrene Hospitalization 7/19/2009 Female 223 lb 9/24/2009 Physician Poland
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 9/22/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 12/1/2008 52 Female 9/21/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 12/28/2009 United States
Primary
Concomitant
Vomiting Other Serious 8/3/2009 70 Female 154 lb 2/3/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Urinary Tract Obstruction Hospitalization 76 Male 1/22/2010 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 7/15/2009 70 Female 2/12/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Personality Change Other Serious 1/1/2009 52 Male 2/16/2010 Pharmacist United States
Primary
Concomitant
Job Dissatisfaction 12/1/2007 57 Female 2/26/2010 Consumer United States
Primary
Secondary
Concomitant
Increased Appetite Other Serious 2/1/2010 Female 126 lb 3/2/2010 Consumer Brazil
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/1/2010 Female 121 lb 3/3/2010 Consumer Brazil
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 2/28/2010 69 Female 146 lb 3/1/2010 Physician United States
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Required Intervention 10/30/2009 53 Female 189 lb 3/4/2010 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/21/2009 Female 154 lb 3/12/2010 Physician Brazil
Primary
Concomitant
Vomiting Life Threatening 2/11/2010 Female 3/19/2010 Physician Argentina
Primary
Concomitant
Septic Shock Hospitalization 1/1/2010 Male 346 lb 3/19/2010 Physician Spain
Primary
Secondary
Concomitant
Spinal Cord Disorder Hospitalization 60 Male 176 lb 3/26/2010 Consumer Brazil
Primary
Secondary
Concomitant
Platelet Count Increased Other Serious 3/1/2009 Male 185 lb 3/26/2010 Pharmacist United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 1/1/2010 Male 346 lb 3/26/2010 Physician Spain
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/11/2010 Female 3/26/2010 Physician Argentina
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/24/2010 59 Male 143 lb 3/26/2010 United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/11/2010 Female 3/29/2010 Physician Argentina
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Female 200 lb 3/29/2010 Physician United States
Primary
Concomitant
Urinary Incontinence Other Serious 2/1/2010 94 Female 126 lb 4/13/2010 Consumer Brazil
Primary
Secondary
Concomitant
Visual Field Defect Other Serious 8/1/2009 66 Male 250 lb 4/23/2010 Consumer United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2009 51 Male 192 lb 5/10/2010 Consumer United States
Primary
Concomitant
Mixed Hepatocellular Cholangiocarcinoma Life Threatening Male 5/10/2010 Other Health Professional Germany
Primary
Concomitant
Skin Ulcer Hospitalization 1/29/2010 64 Male 160 lb 5/12/2010 Physician United States
Primary
Concomitant
Vomiting Life Threatening 4/5/2010 54 Male 192 lb 5/12/2010 Physician United States
Primary
Secondary
Concomitant
H1n1 Influenza Other Serious 7/2/2009 53 Female 148 lb 5/13/2010 Other Health Professional Chile
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 5/13/2010 United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 4/8/2010 78 Female 142 lb 5/14/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 6/6/2009 16 Male 209 lb 5/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/17/2010 81 Female 148 lb 6/1/2010 Consumer Brazil
Primary
Concomitant
Syncope Other Serious 4/15/2009 54 Male 6/4/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Impairment Required Intervention 2/22/2010 61 Female 6/10/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 60 Female 6/11/2010 United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 4/9/2010 50 Male 261 lb 6/23/2010 United States
Primary
Secondary
Concomitant
Swelling Face 11/1/2008 76 Female 145 lb 6/29/2010 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 6/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/1/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 70 Female 7/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/12/2010 Physician Israel
Primary
Secondary
Concomitant
Swelling Face Life Threatening 6/21/2010 64 Male 7/16/2010 Consumer United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/20/2010 Physician Israel
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 1/1/2006 48 Male 190 lb 7/31/2010 Consumer United States
Primary
Concomitant
Visual Field Defect Other Serious 8/1/2009 66 Male 250 lb 8/26/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 62 Female 8/20/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vomiting Other Serious 5/17/2010 81 Female 148 lb 9/28/2010 Consumer Brazil
Primary
Concomitant
Pancreatitis Acute Hospitalization 6/22/2010 44 Female 200 lb 10/7/2010 Physician United States
Primary
Concomitant
Nervousness Other Serious 9/1/2010 57 Female 165 lb 10/22/2010 Consumer Brazil
Primary
Concomitant
Muscle Spasms 1/1/2008 Male 210 lb 10/26/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2008 68 Male 163 lb 10/28/2010 Physician United States
Primary
Concomitant
Gastric Cancer Hospitalization 10/29/2010 76 Male 148 lb 11/10/2010 Physician Japan
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 10/1/2010 76 Male 148 lb 11/17/2010 Physician Japan
Primary
Secondary
Concomitant
Large Intestine Carcinoma Hospitalization 10/1/2010 76 Male 148 lb 12/3/2010 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2010 72 Female 172 lb 12/20/2010 Consumer Brazil
Primary
Concomitant
Large Intestine Carcinoma Hospitalization 10/1/2010 76 Male 148 lb 12/22/2010 Physician Japan
Primary
Secondary
Concomitant
Nervousness Other Serious 9/1/2010 57 Female 165 lb 12/30/2010 Consumer Brazil
Primary
Concomitant
Confusional State Other Serious 2/1/2010 94 Female 126 lb 2/4/2011 Consumer Brazil
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 7/31/2010 84 Female 2/7/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 7/31/2010 84 Female 2/8/2011 Other Health Professional Spain
Primary
Secondary
Concomitant
Joint Sprain Hospitalization 10/25/2004 70 Male 212 lb 2/11/2011 Physician United States
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 11/12/2010 45 Male 214 lb 2/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 52 Male 2/8/2011 Other Health Professional Brazil
Primary
Concomitant
Lactic Acidosis Hospitalization 11/27/2010 72 Male 2/18/2011 Other Health Professional Sweden
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 11/12/2010 45 Male 214 lb 5/4/2011 Physician United States
Primary
Secondary
Concomitant
Heart Rate Decreased Hospitalization 1/1/2007 79 Female 5/12/2011 Consumer Brazil
Primary
Concomitant
Thrombocytopenia Hospitalization 1/1/2011 54 Female 5/23/2011 Physician United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 3/25/2011 78 Male 6/3/2011 Other Health Professional Denmark
Primary
Secondary
Concomitant
Pain Hospitalization 1/1/2010 63 Female 176 lb 6/15/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Hyperhidrosis Other Serious 64 Female 172 lb 6/17/2011 Physician Brazil
Primary
Concomitant
Emotional Disorder Hospitalization 1/1/2009 69 Male 282 lb 7/21/2011 Consumer Brazil
Primary
Secondary
Concomitant
Bladder Cancer Other Serious 65 Female 7/14/2011 Other Health Professional Japan
Primary
Concomitant
Choking Sensation 1/1/2010 80 Male 8/20/2011 Consumer United States
Primary
Concomitant
Ischaemic Stroke Hospitalization 2/9/2011 80 Female 132 lb 8/22/2011 Physician Argentina
Primary
Concomitant
Vomiting Hospitalization 6/4/2011 77 Female 105 lb 8/24/2011 Physician Malaysia
Primary
Concomitant
Coronary Artery Stenosis Hospitalization 1/1/2000 60 Female 205 lb 8/29/2011 Consumer United States
Primary
Concomitant
Impaired Work Ability Disability 11/15/2010 54 Male 8/26/2011 Physician Denmark
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 64 Male 9/1/2011 Sweden
Primary
Secondary
Concomitant
Fluid Retention Disability 11/15/2010 54 Male 9/2/2011 Physician Denmark
Primary
Secondary
Concomitant
Completed Suicide Death 15 9/22/2011 Other Health Professional United States
Primary
Secondary
Renal Failure Acute Hospitalization 82 Male 9/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fluid Retention Disability 11/15/2010 54 Male 9/30/2011 Physician Denmark
Primary
Secondary
Concomitant
Drug Interaction Other Serious 7/6/2011 88 Female 10/5/2011 Physician Spain
Primary
Concomitant
Interacting
Vomiting Hospitalization 7/6/2011 88 Female 10/5/2011 Other Health Professional Spain
Primary
Concomitant
Interacting
Renal Failure Other Serious 10/26/2007 71 Female 401 lb 10/6/2011 Lawyer United States
Primary
Concomitant
Diarrhoea 1/22/2011 63 Male 190 lb 10/7/2011 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 6/18/2011 64 Male 245 lb 10/7/2011 Physician United Kingdom
Primary
Concomitant
Electrolyte Imbalance Hospitalization 6/9/2011 Female 187 lb 10/10/2011 Physician Denmark
Primary
Concomitant
Ischaemic Stroke Death 6/17/2011 70 Female 154 lb 10/11/2011 Physician Chile
Primary
Concomitant
Chest Pain Hospitalization 1/1/2007 68 Female 154 lb 10/11/2011 Other Health Professional United States
Primary
Concomitant
Chest Pain Other Serious 44 Female 10/13/2011 Physician Brazil
Primary
Secondary
Blood Triglycerides Increased Hospitalization 44 Female 10/13/2011 Brazil
Primary
Secondary
Glycosylated Haemoglobin Increased Other Serious 68 Female 10/14/2011 Brazil
Primary
Secondary
Concomitant
Incontinence Other Serious 10/26/2007 71 Female 401 lb 10/14/2011 Lawyer United States
Primary
Concomitant
Left Ventricular Hypertrophy Other Serious 68 Female 10/14/2011 Brazil
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 51 Female 10/17/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Intraocular Pressure Increased 45 Female 235 lb 10/18/2011 Consumer United States
Primary
Concomitant
Vaginal Haemorrhage Other Serious 8/1/2011 60 Female 150 lb 9/28/2011 Consumer Brazil
Primary
Concomitant

Drug Data