Enalapril Maleate combined with Isosorbide Mononitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombosis Hospitalization 1/20/2001 Male 1/3/2006 France
Primary
Concomitant
Shock Life Threatening 67 Female 1/9/2006 United Kingdom
Primary
Secondary
Renal Failure Acute Hospitalization 67 Female 2/9/2006 Consumer United Kingdom
Primary
Secondary
Shock Hospitalization 67 Female 2/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Shock Life Threatening 67 Female 2/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Renal Failure Acute Life Threatening 67 Female 2/13/2006 United Kingdom
Primary
Secondary
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 2/23/2006 Physician Germany
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 1/6/2006 51 Female 2/10/2006 United Kingdom
Primary
Concomitant
Eye Operation Other Serious 1/6/2006 51 Female 2/20/2006 Pharmacist United Kingdom
Primary
Concomitant
Shock Hospitalization 67 Female 3/10/2006 Consumer United Kingdom
Primary
Secondary
Rhabdomyolysis Hospitalization 1/1/2005 76 Female 3/16/2006 Other Health Professional Italy
Primary
Concomitant
Odynophagia Hospitalization 1/15/2006 71 Male 3/10/2006 Physician Japan
Primary
Secondary
Condition Aggravated Other Serious 1/1/2006 54 Male 269 lb 3/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2005 76 Female 3/23/2006 Other Health Professional Italy
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2004 60 Male 3/17/2006 Consumer Brazil
Primary
Concomitant
Sinoatrial Block Hospitalization 67 Female 3/17/2006 Other Health Professional United Kingdom
Primary
Secondary
Angioneurotic Oedema Hospitalization 1/15/2006 71 Male 3/17/2006 Physician Japan
Primary
Secondary
Sinoatrial Block Hospitalization 67 Female 3/14/2006 United Kingdom
Primary
Secondary
Concomitant
Shock Hospitalization 67 Female 3/15/2006 United Kingdom
Primary
Secondary
Urticaria Life Threatening 2/28/2006 68 Male 3/15/2006 Singapore
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2005 76 Female 3/30/2006 Other Health Professional Italy
Primary
Concomitant
Urticaria Life Threatening 2/28/2006 68 Male 3/22/2006 Physician Singapore
Primary
Concomitant
Urticaria Life Threatening 2/28/2006 68 Male 3/21/2006 Physician Singapore
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 5/29/2002 Female 4/3/2006 Lawyer Poland
Primary
Concomitant
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 3/30/2006 Physician Germany
Primary
Secondary
Concomitant
Shock Hospitalization 67 Female 3/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Wrong Technique In Drug Usage Process Hospitalization 5/29/2002 Female 4/11/2006 Physician Poland
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 1/15/2006 71 Male 4/3/2006 Physician Japan
Primary
Secondary
Sepsis Hospitalization 2/6/2006 59 Male 128 lb 4/5/2006 Physician Germany
Primary
Secondary
Concomitant
Road Traffic Accident Hospitalization 6/23/2002 72 Male 192 lb 4/20/2006 Lawyer United States
Primary
Concomitant
Road Traffic Accident Hospitalization 6/23/2002 72 Male 192 lb 4/26/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/6/2006 59 Male 128 lb 4/18/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 4/1/2004 60 Male 4/25/2006 Brazil
Primary
Concomitant
White Blood Cell Count Decreased Death 7/30/2005 66 Male 203 lb 5/3/2006 Other Health Professional Hungary
Primary
Secondary
Concomitant
Syncope Required Intervention 12/1/2005 77 Female 12/2/2005 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/9/2006 56 Male 205 lb 6/23/2006 Physician Brazil
Primary
Concomitant
Loss Of Consciousness Hospitalization Male 6/30/2006 Pharmacist Japan
Primary
Concomitant
Varicose Vein Hospitalization 1/31/2006 66 Female 190 lb 6/26/2006 Other Health Professional Poland
Primary
Concomitant
Renal Failure Acute Hospitalization 6/9/2006 56 Male 205 lb 7/5/2006 Physician Brazil
Primary
Concomitant
Bronchitis Hospitalization 10/22/2005 64 Male 7/14/2006 United States
Primary
Secondary
Concomitant
Haematemesis Hospitalization 6/14/2006 72 Male 123 lb 7/7/2006 Pharmacist United States
Primary
Concomitant
Sepsis Hospitalization 7/20/2006 56 Male 203 lb 8/10/2006 Physician Brazil
Primary
Concomitant
Syncope Hospitalization 7/26/2006 64 Male 205 lb 8/17/2006 Consumer United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/20/2006 56 Male 203 lb 8/22/2006 Physician Brazil
Primary
Concomitant
Sepsis Hospitalization 7/18/2006 56 Male 203 lb 9/1/2006 Brazil
Primary
Concomitant
Drug Interaction Other Serious 7/22/2006 74 Male 9/1/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 7/18/2006 56 Male 203 lb 9/1/2006 Brazil
Primary
Concomitant
Drug Interaction Other Serious 7/22/2006 74 Male 9/1/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Rhinorrhoea Hospitalization 8/8/2006 60 Male 234 lb 9/12/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/18/2006 56 Male 203 lb 9/18/2006 Other Health Professional Brazil
Primary
Concomitant
Thrombocytopenia Other Serious 7/18/2006 56 Male 203 lb 9/27/2006 Other Health Professional Brazil
Primary
Concomitant
Vomiting Hospitalization 2/7/2006 59 Male 128 lb 9/27/2006 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/18/2006 56 Male 203 lb 10/10/2006 Other Health Professional Brazil
Primary
Concomitant
Hypotension Hospitalization 9/9/2006 64 Male 265 lb 9/29/2006 Pharmacist United States
Primary
Secondary
Renal Failure Acute Life Threatening 8/11/2006 64 Male 11/2/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/5/2006 91 Female 11/3/2006 Sweden
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/18/2006 56 Male 203 lb 12/13/2006 Other Health Professional Brazil
Primary
Concomitant
Upper Respiratory Tract Infection Life Threatening 1/1/2003 76 Male 12/21/2006
Primary
Secondary
Concomitant
Syncope Vasovagal Life Threatening 1/1/2003 76 Male 12/29/2006 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 8/10/2006 80 Male 12/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Shock Hospitalization 67 Female 1/23/2007 Consumer United Kingdom
Primary
Secondary
Hypertension Hospitalization 1/25/2007 Male 173 lb 3/1/2007 Physician Germany
Primary
Concomitant
Shock Hospitalization 67 Female 3/12/2007 Consumer United Kingdom
Primary
Secondary
Implantable Defibrillator Insertion Hospitalization 1/25/2007 Male 173 lb 3/27/2007 Physician Germany
Primary
Concomitant
Melaena Hospitalization 1/22/2007 61 Male 3/28/2007 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 7/21/2006 Male 203 lb 4/2/2007 Brazil
Primary
Concomitant
Tetany Other Serious 1/26/2007 76 Female 4/5/2007 Consumer France
Primary
Concomitant
Thrombocytopenia Hospitalization 7/18/2006 Male 203 lb 4/13/2007 Brazil
Primary
Concomitant
Hypoglycaemia Other Serious 12/4/2006 58 Male 201 lb 4/26/2007 Physician United States
Primary
Concomitant
Thrombocytopenia Hospitalization 7/18/2006 Male 203 lb 6/28/2007 Brazil
Primary
Concomitant
Skin Hypertrophy Other Serious 70 Male 6/29/2007 Other Health Professional Greece
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 67 Female 7/27/2007 Physician United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 67 Female 9/14/2007 Other Health Professional United Kingdom
Primary
Secondary
Unresponsive To Stimuli Life Threatening 67 Female 9/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Unresponsive To Stimuli Life Threatening 67 Female 9/11/2007 United Kingdom
Primary
Secondary
Sepsis Hospitalization 2/6/2006 Male 128 lb 9/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 67 Female 9/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Shock Life Threatening 67 Female 9/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Unresponsive To Stimuli Life Threatening 67 Female 8/24/2007 United Kingdom
Primary
Secondary
Rhabdomyolysis Hospitalization 8/6/2007 50 Male 10/19/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 1/1/2003 67 Female 10/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/6/2007 50 Male 10/23/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/6/2007 50 Male 10/25/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Tachycardia Other Serious 9/21/2007 Female 10/31/2007 Physician China
Primary
Concomitant
Sinoatrial Block Life Threatening 1/1/2003 67 Female 10/31/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 9/21/2007 Female 11/9/2007 Physician China
Primary
Concomitant
Drug Ineffective 57 Male 11/13/2007 Consumer United States
Primary
Concomitant
Cholecystitis Acute Death 7/1/2007 75 Female 108 lb 11/5/2007 Physician Japan
Primary
Concomitant
Pain In Extremity 75 Male 11/16/2007 Pharmacist United States
Primary
Concomitant
Vertigo Life Threatening 1/1/2007 72 Male 12/13/2007 Physician Poland
Primary
Concomitant
Erythema Hospitalization 1/1/2007 87 Female 126 lb 1/2/2008 Other Health Professional Finland
Primary
Concomitant
Myoclonus Death 10/1/2007 92 Female 2/11/2008 Other Health Professional Spain
Primary
Concomitant
Hypotension Other Serious 7/6/2007 50 Male 2/15/2008 Physician Philippines
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/6/2007 50 Male 3/7/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 68 Female 4/18/2008 Physician Czech Republic
Primary
Secondary
Concomitant
Hypotension Other Serious 7/6/2007 Male 4/21/2008 Philippines
Primary
Secondary
Concomitant
Amyotrophic Lateral Sclerosis Other Serious 3/1/2007 68 Male 4/24/2008 Other Health Professional Sweden
Primary
Concomitant
Thrombocytopenia Hospitalization 4/3/2008 71 Male 176 lb 5/9/2008 Consumer United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 7/18/2006 Male 203 lb 5/16/2008 Brazil
Primary
Concomitant
Thrombocytopenia Hospitalization 7/18/2006 Male 203 lb 6/12/2008 Brazil
Primary
Concomitant
Polyneuropathy Other Serious 60 Male 5/30/2008 Physician Sweden
Primary
Concomitant
Vomiting Other Serious 3/2/2008 Female 242 lb 6/18/2008 Physician United Kingdom
Primary
Concomitant
Suicide Attempt Other Serious 1/1/2005 Male 6/17/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/18/2006 Male 203 lb 7/15/2008 Brazil
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 6/26/2008 Female 140 lb 8/11/2008 Physician United States
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 5/22/2008 48 Male 8/27/2008 Sweden
Primary
Concomitant
Swelling Face 5/12/2008 Female 249 lb 8/27/2008 Other Health Professional United States
Primary
Concomitant
Trigger Finger Hospitalization 5/3/2007 77 Male 9/3/2008 Japan
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 5/22/2008 48 Male 133 lb 9/9/2008 Sweden
Primary
Concomitant
Syncope Other Serious 9/11/2008 Male 154 lb 9/17/2008 Physician Brazil
Primary
Concomitant
Trigger Finger Hospitalization 5/3/2007 77 Male 9/22/2008 Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/6/2007 50 Male 9/29/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 11/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 11/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Trigger Finger Hospitalization 5/3/2007 77 Male 11/21/2008 Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Incontinence Life Threatening 11/11/2008 Female 127 lb 11/17/2008 Pharmacist United States
Primary
Concomitant
Product Quality Issue Death 11/21/2008 86 Male 180 lb 12/15/2008 Consumer United States
Primary
Concomitant
Splenomegaly Other Serious 1/20/2008 12/22/2008 Other Health Professional Singapore
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2008 Male 188 lb 12/24/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 11/12/2008 81 Female 175 lb 12/30/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/20/2008 1/30/2009 Other Health Professional Singapore
Primary
Secondary
Concomitant
Stent Placement Other Serious 1/1/2000 Male 2/4/2009 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 3/11/2007 80 Male 3/6/2009 Other Health Professional Austria
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 80 Male 3/6/2009 Austria
Primary
Secondary
Concomitant
Anaphylactic Shock Life Threatening 3/11/2009 71 Male 3/19/2009 Physician Japan
Primary
Concomitant
Bronchitis Hospitalization 3/29/2007 77 5/25/2009 Physician Poland
Primary
Secondary
Concomitant
Visual Acuity Reduced Hospitalization 10/8/2008 Male 5/27/2009 Other Health Professional Poland
Primary
Secondary
Vomiting Hospitalization 47 Female 163 lb 7/7/2009 Lawyer United States
Primary
Concomitant
Pneumonia Hospitalization 5/1/2002 83 Female 130 lb 7/22/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 5/1/2002 47 Female 255 lb 7/23/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious Female 176 lb 7/23/2009 Consumer United States
Primary
Concomitant
Sepsis Death 7/1/2007 75 Female 108 lb 7/24/2009 Physician Japan
Primary
Concomitant
Sepsis Death 7/1/2007 75 Female 108 lb 8/10/2009 Physician Japan
Primary
Concomitant
Ischaemic Stroke Hospitalization 1/1/2008 Male 8/19/2009 Poland
Primary
Secondary
Weight Decreased Other Serious 76 Male 9/1/2009 Lawyer United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 7/27/2009 93 Female 9/4/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tooth Loss Other Serious Female 9/16/2009 Consumer Brazil
Primary
Concomitant
Tremor Other Serious 64 Female 9/21/2009 Consumer Brazil
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 10/8/2008 Male 9/29/2009 Poland
Primary
Secondary
Muscle Rupture Hospitalization 69 Male 10/8/2009 Other Health Professional Netherlands
Primary
Concomitant
Interacting
Wheezing Death 6/12/2008 69 Male 10/13/2009 Lawyer United States
Primary
Concomitant
Tooth Loss Other Serious Female 11/3/2009 Consumer Brazil
Primary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 11/2/2009 United Kingdom
Primary
Concomitant
Muscle Rupture Hospitalization 69 Male 11/16/2009 Other Health Professional Netherlands
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 10/21/2008 72 Female 11/10/2009
Primary
Secondary
Concomitant
Peritonitis Bacterial Other Serious 3/5/2009 76 Male 168 lb 11/3/2009 Other Health Professional United States
Primary
Concomitant
Wound Complication Other Serious 5/1/2009 Female 108 lb 1/20/2010 Brazil
Primary
Concomitant
Ventricular Tachycardia Other Serious 65 Male 1/12/2010 United States
Primary
Concomitant
Urinary Tract Obstruction Hospitalization 76 Male 1/22/2010 United States
Primary
Concomitant

Drug Data