Enalapril Maleate combined with Isosorbide Dinitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rhabdomyolysis Hospitalization 1/1/2005 76 Female 3/23/2006 Other Health Professional Italy
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2005 76 Female 3/30/2006 Other Health Professional Italy
Primary
Concomitant
Renal Disorder Hospitalization 76 Male 5/19/2006 Other Health Professional Japan
Primary
Concomitant
Interacting
Myalgia Hospitalization 1/1/2006 65 Male 5/19/2006 Physician Germany
Primary
Secondary
Concomitant
Jaundice Hospitalization 68 Female 6/9/2006 Pharmacist Japan
Primary
Concomitant
Myalgia Hospitalization 1/1/2006 65 Male 152 lb 6/14/2006 Physician Germany
Primary
Secondary
Concomitant
Pruritus Hospitalization 3/14/2006 68 Female 6/22/2006 Pharmacist Japan
Primary
Concomitant
Cholestasis Hospitalization 3/14/2006 Female 7/10/2006 Pharmacist Japan
Primary
Concomitant
Dehydration Hospitalization 4/26/2006 85 Male 200 lb 5/15/2006 Pharmacist United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 4/1/2006 62 Male 7/26/2006 Other Health Professional United States
Primary
Concomitant
Hyperkalaemia Hospitalization 6/20/2006 70 Male 9/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Schizophrenia Other Serious 4/1/1997 68 Female 9/22/2006 Physician Japan
Primary
Concomitant
Leukocytosis Hospitalization 11/15/2005 55 Female 1/5/2007 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 83 Male 2/27/2007
Primary
Secondary
Concomitant
Angioedema Disability 1/1/2007 47 Male 3/28/2007 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 1/1/2005 86 Male 160 lb 12/13/2006 Consumer United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 5/1/2007 70 Male 154 lb 7/13/2007 Physician Japan
Primary
Secondary
Concomitant
Feeling Abnormal 3/1/2007 80 Female 8/3/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 8/11/2007 89 Male 9/26/2007 Consumer Brazil
Primary
Secondary
Concomitant
Chest Pain Life Threatening 9/7/2007 54 Male 252 lb 10/5/2007 Physician Russian Federation
Primary
Concomitant
Dilatation Ventricular Life Threatening 9/7/2007 54 Male 252 lb 10/23/2007 Physician Russian Federation
Primary
Concomitant
Somnolence Other Serious 9/17/2007 61 269 lb 11/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Other Serious 8/1/2004 65 Female 190 lb 1/9/2008 Physician Poland
Primary
Concomitant
Refusal Of Treatment By Patient Life Threatening 12/1/2007 63 Male 1/14/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/14/2008 57 Male 2/4/2008 Physician Belarus
Primary
Concomitant
Ventricular Tachycardia Life Threatening 11/19/2007 63 Male 294 lb 1/31/2008 United States
Primary
Concomitant
Hypotension Other Serious 7/6/2007 50 Male 2/15/2008 Physician Philippines
Primary
Secondary
Concomitant
Hypotension Other Serious 7/6/2007 Male 4/21/2008 Philippines
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 1/1/2006 74 Male 5/17/2008 Consumer
Primary
Concomitant
Incontinence Hospitalization 5/1/2008 82 Female 176 lb 6/9/2008 United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization Female 164 lb 7/1/2008 Consumer United States
Primary
Secondary
Concomitant
Angina Unstable Other Serious 6/1/2005 68 Male 7/1/2008 Other Health Professional Argentina
Primary
Secondary
Concomitant
Syncope Other Serious 8/1/2004 65 Female 190 lb 7/7/2008 Physician Poland
Primary
Concomitant
Tachycardia Other Serious 6/21/2008 12 Female 104 lb 7/1/2008 Physician Brazil
Primary
Secondary
Coronary Artery Occlusion Hospitalization Female 164 lb 7/18/2008 Consumer United States
Primary
Secondary
Concomitant
Dilatation Ventricular Life Threatening 9/7/2007 Male 252 lb 7/21/2008 Physician Russian Federation
Primary
Concomitant
Swollen Tongue Other Serious 5/23/2008 71 Male 7/25/2008 Consumer United States
Primary
Concomitant
Renal Disorder Hospitalization 12/1/2007 73 Female 7/29/2008 Consumer United Kingdom
Primary
Concomitant
Weight Increased Death 7/1/2008 56 Female 157 lb 7/23/2008 Physician United States
Primary
Concomitant
Muscle Spasms Male 8/29/2008 United States
Primary
Concomitant
Myalgia Hospitalization 1/1/2007 72 Male 12/4/2008 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection 9/19/2008 Female 195 lb 12/12/2008 United States
Primary
Concomitant
Vomiting Other Serious 10/25/2006 56 Female 132 lb 12/16/2008 Physician Germany
Primary
Concomitant
Vomiting Other Serious 10/25/2006 56 Female 132 lb 12/18/2008 Physician Germany
Primary
Concomitant
Orthostatic Hypotension Other Serious Male 12/19/2008 France
Primary
Secondary
Concomitant
Vomiting Other Serious 10/25/2006 56 Female 132 lb 12/26/2008 Physician Germany
Primary
Concomitant
Lung Disorder Death 9/29/2008 50 Male 1/6/2009 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Other Serious Male 1/16/2009 France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2008 65 Male 198 lb 1/30/2009 Physician Austria
Primary
Concomitant
Renal Failure Acute Hospitalization 7/4/2008 80 Male 176 lb 4/23/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 7/4/2008 80 Male 5/21/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 190 lb 6/9/2009 Other Health Professional United States
Primary
Concomitant
Wound Dehiscence Other Serious 7/10/2003 Male 6/25/2009 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Other Serious 76 Male 7/15/2009 Lawyer United States
Primary
Concomitant
Diabetes Mellitus Female 189 lb 7/22/2009 United States
Primary
Concomitant
Diabetic Foot Other Serious 1/1/2004 45 Male 200 lb 7/29/2009 Other Health Professional United States
Primary
Concomitant
Pruritus 11/7/2008 Female 8/22/2009 United States
Primary
Concomitant
Rash Macular 7/20/2009 Female 160 lb 8/23/2009 Consumer United States
Primary
Concomitant
Laboratory Test Abnormal Other Serious 75 Female 9/28/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Other Serious 55 Male 10/9/2009 Japan
Primary
Concomitant
Overdose Death 10/20/2009 83 Male 10/27/2009 Physician Italy
Primary
Concomitant
Thrombosis In Device Other Serious 55 Female 115 lb 10/22/2009 Physician Japan
Primary
Secondary
Concomitant
Overdose Death 10/20/2009 83 Male 11/26/2009 Physician Italy
Primary
Concomitant
Vomiting Life Threatening 2/11/2010 Female 3/26/2010 Physician Argentina
Primary
Concomitant
Vomiting Life Threatening 2/11/2010 Female 3/29/2010 Physician Argentina
Primary
Concomitant
Vomiting Life Threatening 2/11/2010 81 Female 4/9/2010 Physician Argentina
Primary
Concomitant
Cardiomyopathy Hospitalization 7/3/2008 41 Male 163 lb 4/20/2010 Consumer Ecuador
Primary
Secondary
Concomitant
Vascular Occlusion Hospitalization Male 191 lb 4/26/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 10/13/2009 66 Male 171 lb 5/6/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Skin Tightness Other Serious 8/1/2006 57 Male 192 lb 6/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 8/1/2006 57 Male 192 lb 6/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 10/14/2002 41 Female 165 lb 7/26/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2009 56 Female 9/17/2010 Consumer Brazil
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 10/13/2009 66 Male 171 lb 9/30/2010 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Visual Impairment Other Serious 4/10/2009 55 Female 185 lb 10/14/2010 Consumer Brazil
Primary
Concomitant
Visual Impairment Other Serious 4/10/2009 55 Female 185 lb 10/15/2010 Consumer Brazil
Primary
Concomitant
Renal Failure Acute Hospitalization 7/4/2008 80 Male 176 lb 10/19/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/4/2008 80 Male 176 lb 10/19/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Hypertensive Crisis Hospitalization 69 Male 198 lb 10/22/2010 Physician Germany
Primary
Concomitant
Stent Placement Other Serious 1/1/2004 45 Female 10/25/2010 Consumer Brazil
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 7/4/2008 80 Male 10/19/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Oxygen Saturation Decreased 76 Male 10/13/2010 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization Male 198 lb 11/3/2010 Physician Germany
Primary
Concomitant
Visual Impairment Hospitalization 1/1/2004 45 Female 11/3/2010 Consumer Brazil
Primary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 8/28/2009 88 Male 150 lb 11/18/2010 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Death 10/18/2010 82 Female 93 lb 12/2/2010 Physician
Primary
Concomitant
Herpes Zoster Other Serious 8/25/2010 75 Male 137 lb 12/27/2010 Physician Japan
Primary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 12/29/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Herpes Zoster Other Serious 8/25/2010 75 Male 137 lb 1/5/2011 Physician Japan
Primary
Concomitant
Herpes Zoster Other Serious 8/25/2010 75 Male 137 lb 1/28/2011 Physician Japan
Primary
Concomitant
Injection Site Haematoma 73 Female 1/30/2011 Consumer United States
Primary
Concomitant
Dizziness 73 Female 1/30/2011 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2009 45 Female 2/4/2011 Pharmacist United States
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 2/21/2011 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Death 1/1/2011 77 Male 192 lb 4/12/2011 Physician Switzerland
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2006 45 Female 4/14/2011 Lawyer United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 7/14/2010 56 Male 272 lb 4/15/2011 Physician United States
Primary
Secondary
Concomitant
Anhedonia Hospitalization 12/15/2005 56 Male 146 lb 4/18/2011 Consumer United States
Primary
Concomitant
Circulatory Collapse Death 1/1/2011 77 Male 192 lb 4/21/2011 Physician Switzerland
Primary
Secondary
Concomitant
Nervousness 3/11/2011 81 Female 5/24/2011 Consumer United States
Primary
Concomitant
Pain Other Serious 64 Male 216 lb 5/24/2011 Consumer United States
Primary
Concomitant
Chest X-ray Abnormal Hospitalization 6/1/2001 75 Male 6/13/2011 Other Health Professional Japan
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 10/12/2010 73 Male 154 lb 6/17/2011 Physician Japan
Primary
Concomitant
Parkinsonism Other Serious 1/1/2003 Female 6/20/2011 Physician Japan
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 7/2/2010 77 Male 7/5/2011 Physician Japan
Primary
Concomitant
Anaphylactic Reaction Life Threatening 6/11/2011 67 Male 137 lb 7/8/2011 Physician Japan
Primary
Concomitant
Skin Discolouration Hospitalization 1/1/2005 57 Male 7/13/2011 Lawyer United States
Primary
Secondary
Concomitant
Peroneal Nerve Palsy Hospitalization 6/18/2011 64 Male 245 lb 7/13/2011 Other Health Professional United Kingdom
Primary
Concomitant
Parkinsonism Other Serious 1/1/2003 Female 7/18/2011 Physician Japan
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 1/1/2003 76 Female 160 lb 7/20/2011 Other Health Professional United States
Primary
Concomitant
Influenza Other Serious 9/1/2010 62 Female 7/13/2011 Consumer Brazil
Primary
Concomitant
Anaphylactic Reaction Life Threatening 6/11/2011 67 Male 137 lb 7/25/2011 Physician Japan
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2007 69 Female 147 lb 8/2/2011 Lawyer United States
Primary
Concomitant
Renal Injury Other Serious 1/1/2003 76 Female 160 lb 8/8/2011 Other Health Professional United States
Primary
Concomitant
Anaphylactic Reaction Life Threatening 6/11/2011 67 Male 137 lb 8/8/2011 Physician Japan
Primary
Concomitant
Acute Myocardial Infarction Hospitalization 10/12/2010 73 Male 154 lb 8/9/2011 Physician Japan
Primary
Concomitant
Anaphylactic Reaction Life Threatening 6/11/2011 67 Male 137 lb 8/25/2011 Physician Japan
Primary
Concomitant
Concomitant Disease Progression Hospitalization 3/3/2010 71 Male 229 lb 8/26/2011 Physician Ireland
Primary
Secondary
Concomitant
Angina Unstable Other Serious 7/26/2011 80 Male 137 lb 8/30/2011 Physician Japan
Primary
Concomitant
Blood Glucose Increased Other Serious 7/1/2010 72 Female 111 lb 8/31/2011 Lawyer United States
Primary
Concomitant
Angina Unstable Other Serious 7/26/2011 80 Male 137 lb 9/16/2011 Physician Japan
Primary
Concomitant
Concomitant Disease Progression Life Threatening 7/14/2010 56 Male 272 lb 9/19/2011 Physician United States
Primary
Secondary
Concomitant
Circulatory Collapse Hospitalization 3/6/2010 67 Male 176 lb 9/28/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 2/9/2011 79 Female 112 lb 10/3/2011 Physician Japan
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 6/18/2011 64 Male 245 lb 10/7/2011 Physician United Kingdom
Primary
Concomitant
Blood Creatine Phosphokinase Increased 5/24/2011 80 Male 137 lb 10/10/2011 Physician Japan
Primary
Concomitant
Myocardial Infarction Hospitalization 5/9/2010 10/11/2011 Consumer United States
Primary
Concomitant
Eosinophil Count Increased Hospitalization 7/2/2010 77 Male 10/17/2011 Physician Japan
Primary
Concomitant
Rash Erythematous 1/29/2010 78 Male 10/24/2011 Physician Japan
Primary
Concomitant
Chest Discomfort 10/2/2011 69 Female 10/25/2011 Pharmacist United States
Primary
Concomitant
Hypotension Life Threatening 3/6/2010 67 Male 176 lb 10/25/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Concomitant Disease Progression Hospitalization 7/14/2010 56 Male 272 lb 10/26/2011 Physician United States
Primary
Secondary
Concomitant
Walking Aid User Hospitalization 2/1/2009 83 Female 168 lb 10/27/2011 Lawyer United States
Primary
Concomitant
Blood Bilirubin Increased Hospitalization 2/9/2011 79 Female 112 lb 11/4/2011 Physician Japan
Primary
Concomitant
Dyspnoea 10/2/2011 69 Female 11/30/2011 Pharmacist United States
Primary
Concomitant
Drug Interaction Hospitalization 7/4/2008 80 Male 176 lb 12/1/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypoperfusion Hospitalization 6/28/2011 78 Female 12/1/2011 Physician Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 2/9/2011 79 Female 112 lb 12/1/2011 Physician Japan
Primary
Concomitant
Disease Progression Other Serious 11/10/2011 78 Female 181 lb 12/5/2011 Physician Argentina
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 10/11/2011 94 Male 192 lb 12/7/2011 Physician United States
Primary
Concomitant
Depressed Level Of Consciousness Hospitalization 2/9/2011 79 Female 112 lb 12/8/2011 Physician Japan
Primary
Concomitant
Dermatitis Acneiform Hospitalization 12/15/2010 67 Male 190 lb 12/13/2011 Physician Japan
Primary
Concomitant
Depressed Level Of Consciousness Hospitalization 2/9/2011 79 Female 112 lb 12/30/2011 Physician Japan
Primary
Concomitant
Dyslipidaemia Other Serious 10/1/2011 50 Female 1/3/2012 Consumer Brazil
Primary
Concomitant
Colitis Ischaemic Hospitalization 12/27/2011 65 Male 1/6/2012 Physician Japan
Primary
Secondary
Concomitant
Knee Deformity Other Serious 12/3/2008 78 Female 1/11/2012 Mexico
Primary
Concomitant
International Normalised Ratio Increased Other Serious 11/1/2011 66 Male 1/6/2012 Physician Portugal
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 10/11/2011 94 Male 192 lb 1/12/2012 Physician United States
Primary
Concomitant
Colitis Ischaemic Hospitalization 12/27/2011 65 Male 1/23/2012 Physician Japan
Primary
Secondary
Concomitant
Memory Impairment Other Serious 10/1/2011 50 Female 2/6/2012 Consumer Brazil
Primary
Concomitant

Drug Data