Enalapril Maleate combined with Heparin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Haematuria Life Threatening 11/16/2005 88 Male 1/27/2006 Pharmacist United States
Primary
Concomitant
Thrombosis In Device Other Serious 7/1/2005 60 3/10/2006 Japan
Primary
Concomitant
Supraventricular Tachycardia Other Serious 3/5/2006 66 Female 3/20/2006 Other Health Professional Canada
Primary
Concomitant
Venous Pressure Increased Other Serious 7/1/2005 60 3/23/2006 Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 3/31/2006 52 Female 209 lb 4/3/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 2/21/2006 74 Female 168 lb 4/12/2006 Physician Israel
Primary
Concomitant
Venous Pressure Increased Other Serious 7/1/2005 60 Unknown 4/5/2006 Physician Japan
Primary
Concomitant
Methaemoglobinaemia Life Threatening 6/20/2005 17 Female 117 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 3/28/2006 51 Female 5/9/2006 Other Health Professional Argentina
Primary
Concomitant
Interacting
Supraventricular Tachycardia Other Serious 3/3/2006 66 Female 6/20/2006 Canada
Primary
Concomitant
Thrombocytopenia Hospitalization 6/24/2006 63 Male 7/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 86 Female 7/6/2006 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Other Serious 5/15/2006 50 Male 7/14/2006 Argentina
Primary
Concomitant
Supraventricular Tachycardia Other Serious 3/3/2006 66 Female 7/21/2006 Canada
Primary
Concomitant
Thrombocytopenia Other Serious 80 Male 6/7/2005 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Erosion Other Serious 5/18/2005 16 Male 8/31/2006 Physician Japan
Primary
Secondary
Concomitant
Pharyngeal Oedema Hospitalization 7/2/2006 49 Male 9/1/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 7/28/2006 79 Male 9/12/2006 Physician France
Primary
Concomitant
Haematuria Hospitalization 7/18/2006 67 Male 9/14/2006 Pharmacist United States
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/28/2006 64 Male 139 lb 9/21/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/1/2006 Male 152 lb 10/12/2006 Physician Spain
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious 3/3/2006 66 Female 10/23/2006 Canada
Primary
Concomitant
Rib Fracture Hospitalization 7/30/2006 83 Male 156 lb 10/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 8/3/2006 64 Male 139 lb 11/16/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 8/30/2005 80 Female 11/20/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2006 Male 152 lb 12/1/2006 Physician Spain
Primary
Concomitant
Shock Haemorrhagic Life Threatening 6/16/2006 74 Female 11/27/2006 Physician Germany
Primary
Concomitant
Shock Other Serious 10/1/2006 81 Male 125 lb 1/8/2007 Physician Japan
Primary
Secondary
Concomitant
Occult Blood Positive Required Intervention 8/2/2006 Female 160 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Required Intervention 8/2/2006 Female 160 lb 8/14/2006 Pharmacist United States
Primary
Concomitant
Jaundice Hospitalization 9/20/2006 68 Male 176 lb 1/19/2007 Other Health Professional United States
Primary
Concomitant
Shock Other Serious 10/1/2006 81 Male 125 lb 1/30/2007 Physician Japan
Primary
Secondary
Concomitant
Urticaria 2/1/2007 73 Female 197 lb 2/16/2007 Pharmacist United States
Primary
Concomitant
Respiratory Failure Life Threatening 1/12/2007 1 Male 2/9/2007 Other Health Professional Japan
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 47 Female 290 lb 2/22/2007 Consumer United States
Primary
Concomitant
Neurological Symptom Other Serious 9/27/2005 Male 251 lb 3/12/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2006 Male 152 lb 3/16/2007 Physician Spain
Primary
Concomitant
Wound Haemorrhage Other Serious 7/7/2006 73 Female 3/19/2007 Other Health Professional South Africa
Primary
Concomitant
Shock Other Serious 10/1/2006 81 Male 125 lb 3/23/2007 Japan
Primary
Secondary
Concomitant
Shock Other Serious 10/1/2006 81 Male 125 lb 4/4/2007 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 1/12/2007 1 Male 4/15/2007 Physician Japan
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 1/12/2007 1 Male 4/25/2007 Physician Japan
Primary
Concomitant
Hepatitis Acute Other Serious 2/12/2006 29 Female 128 lb 6/14/2007 Physician Germany
Primary
Secondary
Concomitant
Sepsis Other Serious 71 Female 170 lb 6/21/2007 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 71 Female 6/26/2007 Physician Belgium
Primary
Secondary
Concomitant
Sepsis Other Serious 71 Female 170 lb 7/5/2007 Physician Germany
Primary
Concomitant
Respiratory Distress Death 12/19/2005 56 Female 127 lb 7/26/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 1/12/2007 1 Male 7/20/2007 Other Health Professional Japan
Primary
Concomitant
Respiratory Failure Death 12/19/2005 56 Female 127 lb 8/1/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Life Threatening 1/12/2007 1 Male 8/3/2007 Physician Japan
Primary
Concomitant
Speech Disorder Hospitalization 2/27/2007 82 Male 183 lb 9/19/2007 Consumer
Primary
Concomitant
Speech Disorder Hospitalization 2/27/2007 82 Male 183 lb 9/21/2007 Consumer
Primary
Concomitant
Vomiting Death 12/19/2005 56 Female 127 lb 10/12/2007 Consumer United States
Primary
Concomitant
Vomiting Death 12/19/2005 56 Female 127 lb 3/5/2008 Consumer United States
Primary
Concomitant
Serotonin Syndrome Other Serious 8/27/2007 67 Male 140 lb 4/6/2008 Physician United States
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Hospitalization 3/6/2008 36 Female 227 lb 4/10/2008 Pharmacist United States
Primary
Concomitant
Polyp Other Serious 5/1/2007 Female 138 lb 4/18/2008 Physician United States
Primary
Concomitant
Dizziness Death 1/11/2008 67 Male 170 lb 5/3/2008 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 6/18/2008 69 Male 154 lb 7/21/2008 Pharmacist France
Primary
Secondary
Concomitant
Thrombosis Hospitalization 8/4/2005 15 Male 159 lb 9/26/2008 Physician United States
Primary
Concomitant
Convulsion Hospitalization 4/10/2008 57 Female 190 lb 10/31/2008 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/4/2005 15 Male 159 lb 11/18/2008 Physician United States
Primary
Concomitant
Haemorrhage Required Intervention 5/22/2008 Female 114 lb 6/24/2008 United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Life Threatening 7/29/2008 39 Female 133 lb 8/4/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Male 178 lb 12/2/2008 Consumer United States
Primary
Concomitant
Convulsion Hospitalization 4/10/2008 Female 190 lb 12/29/2008 Pharmacist United States
Primary
Secondary
Concomitant
Rash Disability 5/4/2008 48 Male 174 lb 12/30/2008 Consumer Switzerland
Primary
Secondary
Rash Maculo-papular Other Serious 5/4/2008 46 Male 174 lb 12/31/2008 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Rash Other Serious 1/1/2008 73 Male 155 lb 1/5/2009 Physician Germany
Primary
Concomitant
Rash Maculo-papular Other Serious 5/4/2008 46 Male 174 lb 1/12/2009 Physician Switzerland
Primary
Secondary
Concomitant
Coronary Artery Thrombosis Hospitalization 1/1/2004 3/12/2009 Physician Japan
Primary
Concomitant
Thrombosis Hospitalization 1/1/2004 3/12/2009 Physician Japan
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 3/17/2009 86 Female 134 lb 3/18/2009 Pharmacist United States
Primary
Concomitant
Skin Lesion Other Serious 1/1/2005 59 Male 7/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious Male 7/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Lesion Other Serious 1/1/2005 59 Male 7/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vitreous Haemorrhage Hospitalization 49 Male 8/14/2009 United States
Primary
Concomitant
Vomiting Hospitalization 49 Male 9/1/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 4/19/2005 52 Female 9/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetic Coma Other Serious 1/1/2002 40 Male 190 lb 9/23/2009 United States
Primary
Concomitant
Respiratory Rate Increased Life Threatening 8/12/2009 84 Female 186 lb 8/13/2009 United States
Primary
Concomitant
Vomiting Hospitalization 49 Male 9/17/2009 United States
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 6/2/2009 Female 198 lb 7/5/2009 Pharmacist United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 33 Female 242 lb 10/8/2009 United States
Primary
Concomitant
Pulmonary Haemorrhage Other Serious 55 Male 10/9/2009 Japan
Primary
Concomitant
Refusal Of Treatment By Relative Hospitalization 11/1/2008 59 Male 10/7/2009 Physician Venezuela
Primary
Concomitant
Thrombosis In Device Other Serious 55 Female 115 lb 10/22/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 8/27/2009 Female 12/1/2009 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 11/1/2008 59 Male 11/23/2009 Physician Venezuela
Primary
Concomitant
Thrombosis Hospitalization 10 Male 1/11/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 65 Female 1/25/2010 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 54 Female 1/15/2010 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 66 Male 1/22/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 10/3/2009 69 Male 2/18/2010 Pharmacist United States
Primary
Secondary
Concomitant
Urosepsis Other Serious 1/1/2005 3/16/2010 Physician United States
Primary
Secondary
Concomitant
Hyperhidrosis Other Serious 1/15/2010 70 Female 109 lb 1/15/2010 Pharmacist United States
Primary
Concomitant
Urosepsis Other Serious 1/1/2005 3/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urosepsis Other Serious 1/1/2005 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urosepsis Other Serious 1/1/2005 4/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/20/2003 61 Female 140 lb 4/8/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 10/1/2004 3 Male 4/16/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 4/8/2010 Lawyer United States
Primary
Concomitant
Wound Infection Pseudomonas Other Serious 10/1/2004 3 Male 4/23/2010 United States
Primary
Concomitant
Wound Infection Pseudomonas Other Serious 10/1/2004 3 Male 5/14/2010 United States
Primary
Concomitant
Intracardiac Thrombus Life Threatening 1/31/2010 53 Female 141 lb 5/11/2010 Physician Sweden
Primary
Concomitant
Wheezing Hospitalization 11/20/2003 61 Female 140 lb 5/18/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/14/2010 20 Female 120 lb 6/4/2010 United States
Primary
Concomitant
Wound Infection Pseudomonas Other Serious 10/1/2004 3 Male 6/21/2010 United States
Primary
Concomitant
Skin Tightness Other Serious 8/1/2006 57 Male 192 lb 6/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 8/1/2006 57 Male 192 lb 6/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/20/2003 61 Female 140 lb 6/21/2010 Lawyer United States
Primary
Secondary
Concomitant
Urosepsis Other Serious 1/1/2005 7/22/2010 United States
Primary
Secondary
Concomitant
Chest Pain Life Threatening 8/4/2010 70 Male 8/5/2010 Pharmacist United States
Primary
Concomitant
Oesophageal Perforation Hospitalization 75 Female 8/5/2010 Germany
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 16 Female 106 lb 8/16/2010 United Kingdom
Primary
Concomitant
Peroneal Nerve Palsy Hospitalization 7/27/2010 62 Female 119 lb 9/1/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Varicose Vein Other Serious 1/1/2009 69 Female 198 lb 9/27/2010 Physician Germany
Primary
Secondary
Concomitant
Anaemia Hospitalization 6/3/2010 66 Male 216 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Varicose Vein Other Serious 1/1/2009 69 Female 207 lb 10/7/2010 Physician Germany
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 8/5/2010 68 Male 183 lb 10/12/2010 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2007 10/21/2010 Other Health Professional United States
Primary
Concomitant
Varicose Vein Other Serious 1/1/2009 11/4/2010 Physician Germany
Primary
Secondary
Concomitant
Ileus Hospitalization 10/22/2010 72 Male 140 lb 11/19/2010 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 3/14/2010 20 Female 120 lb 11/10/2010 United States
Primary
Concomitant
Death Death 12/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 12/29/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Restlessness Death 12/21/2010 83 Male 1/14/2011 Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 6/10/2007 34 Male 1/26/2011 Physician Germany
Primary
Secondary
Concomitant
Catheterisation Cardiac Hospitalization 7/14/2010 56 Male 272 lb 2/7/2011 Physician United States
Primary
Secondary
Concomitant
Plantar Fasciitis Other Serious 1/1/2006 37 Female 152 lb 2/7/2011 Consumer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 1/1/2006 37 Female 152 lb 2/7/2011 Consumer United States
Primary
Concomitant
Right Ventricular Failure Other Serious 1/1/2009 71 Female 207 lb 2/8/2011 Consumer Germany
Primary
Secondary
Concomitant
Shock Death 12/21/2010 83 Male 1/31/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 2/21/2011 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/6/2011 Male 187 lb 2/24/2011 Physician Japan
Primary
Concomitant
Erythrodermic Psoriasis Hospitalization 1/6/2011 51 Male 187 lb 2/25/2011 Physician Japan
Primary
Concomitant
Ileus Hospitalization 10/22/2010 72 Male 140 lb 2/28/2011 Physician Japan
Primary
Concomitant
Otitis Externa Hospitalization 1/6/2011 51 Male 187 lb 2/28/2011 Physician Japan
Primary
Concomitant
Post Procedural Cellulitis Death 4/18/2003 61 Female 230 lb 3/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Post Procedural Cellulitis Other Serious 4/18/2003 61 Female 230 lb 3/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Death 12/21/2010 83 Male 2/17/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Urticaria Other Serious 12/9/2010 50 Male 225 lb 3/9/2011 Pharmacist United States
Primary
Concomitant
Unevaluable Event Other Serious 10/4/2005 2 Female 29 lb 3/11/2011 Other Health Professional United States
Primary
Concomitant
Fear Other Serious 10/4/2005 2 Female 29 lb 3/11/2011 Lawyer United States
Primary
Concomitant
Urticaria Other Serious 12/9/2010 50 Male 225 lb 3/15/2011 Pharmacist United States
Primary
Concomitant
Anxiety Other Serious 8/6/2007 76 Male 3/23/2011 Consumer United States
Primary
Concomitant
Stress Other Serious 8/6/2007 76 Male 3/23/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 12/13/2005 Female 7 lb 3/23/2011 Consumer United States
Primary
Concomitant

Drug Data