Elspar combined with Mercaptopurine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pancreatitis Acute Hospitalization 4/4/1973 4 Male 1/20/2006 Physician United States
Primary
Concomitant
Sepsis Other Serious 15 Male 3/17/2006 United States
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 6 Female 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 10 Female 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Hospitalization 16 Male 5/5/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Thrombocytopenic Purpura Other Serious 16 Male 6/2/2006 Physician Canada
Primary
Secondary
Idiopathic Thrombocytopenic Purpura Other Serious 10 Female 6/3/2006 Physician Canada
Primary
Secondary
Metastasis Other Serious 3 Male 7/25/2006 Physician Turkey
Primary
Secondary
Mucoepidermoid Carcinoma Other Serious 13 Female 7/25/2006 Physician Turkey
Primary
Secondary
Primitive Neuroectodermal Tumour Death 10 Male 7/25/2006 Physician Turkey
Primary
Secondary
Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Staphylococcal Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Enterobacter Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Bacterial Sepsis Death 7/26/2006 Physician United States
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious 3 Male 8/3/2006 Consumer United States
Primary
Secondary
Blood Growth Hormone Decreased Other Serious 12 Female 8/4/2006 Other Health Professional United States
Primary
Secondary
Epiphyseal Disorder Other Serious 15 Male 8/4/2006 Other Health Professional United States
Primary
Secondary
Urinary Incontinence Required Intervention 16 Male 9/1/2006 Other Health Professional Spain
Primary
Concomitant
Urinary Incontinence Required Intervention 1/1/1997 16 Male 9/20/2006 Other Health Professional Spain
Primary
Concomitant
Neurotoxicity Other Serious 7/4/2003 17 Female 10/7/2006 United States
Primary
Concomitant
Malignant Melanoma In Situ Other Serious 22 Male 5/18/2007 Physician United States
Primary
Secondary
Septic Shock Death Male 6/12/2007
Primary
Secondary
Malignant Melanoma Other Serious 17 Male 12/18/2007 United States
Primary
Secondary
Mass Hospitalization 2/4/2008 Physician Hong Kong
Primary
Secondary
Vomiting Other Serious 2 Female 2/7/2008 Physician Canada
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 5 Female 3/10/2008
Primary
Secondary
Concomitant
Protein Total Decreased Other Serious Male 176 lb 4/21/2008 Pharmacist Australia
Primary
Secondary
Concomitant
Chronic Myeloid Leukaemia Life Threatening 54 Male 6/30/2008 Consumer United States
Primary
Secondary
Neoplasm Malignant Life Threatening 54 Male 7/16/2008 United Kingdom
Primary
Secondary
Chronic Myeloid Leukaemia Life Threatening 54 Male 7/17/2008 Consumer United Kingdom
Primary
Secondary
Neoplasm Malignant Life Threatening 54 Male 7/17/2008 United Kingdom
Primary
Secondary
Neoplasm Malignant Life Threatening 54 Male 7/25/2008 United Kingdom
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 7/22/2008 9 Male 76 lb 8/8/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 45 Male 12/2/2008
Primary
Secondary
Thymus Enlargement Required Intervention 14 Male 6/26/2009 Physician China
Primary
Secondary
Thymus Enlargement Other Serious 11 Female 6/26/2009 Other Health Professional China
Primary
Secondary
Thymus Enlargement Other Serious 15 Male 6/26/2009 Other Health Professional China
Primary
Secondary
Thymus Enlargement Other Serious 12 Male 6/26/2009 Other Health Professional China
Primary
Secondary
Thymus Enlargement Required Intervention 6 Male 6/26/2009 Other Health Professional China
Primary
Secondary
Thymus Enlargement Required Intervention 9 Male 6/26/2009 Other Health Professional China
Primary
Secondary
Pyrexia Required Intervention 16 Female 7/16/2009 Other Health Professional Turkey
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 7 Male 57 lb 10/28/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Infection Other Serious 10/26/2009 Physician United States
Primary
Secondary
Infection Other Serious 10/26/2009 Physician United States
Primary
Secondary
Infection Other Serious 10/26/2009 Physician United States
Primary
Secondary
Multi-organ Failure Other Serious 10/26/2009 Physician United States
Primary
Secondary
Multi-organ Failure Other Serious 10/26/2009 United States
Primary
Secondary
Multi-organ Failure Other Serious 10/26/2009 United States
Primary
Secondary
Hepatotoxicity Other Serious 12/21/2009 Poland
Primary
Secondary
Hepatotoxicity Other Serious 12/21/2009 Poland
Primary
Secondary
Hepatotoxicity Other Serious 12/21/2009 Other Health Professional Poland
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 12/21/2009 Other Health Professional Poland
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 12/21/2009 Other Health Professional Poland
Primary
Secondary
Chronic Myeloid Leukaemia Other Serious 54 Male 1/8/2010 Consumer United Kingdom
Primary
Secondary
Vomiting Other Serious 3 Female 29 lb 1/20/2010 Other Health Professional Canada
Primary
Concomitant
Pancreatitis Acute Other Serious 1/22/2010 Thailand
Primary
Secondary
Pancreatitis Acute Other Serious 17 Male 1/25/2010 United States
Primary
Secondary
Pancreatitis Acute Other Serious 15 Male 1/22/2010 Physician United States
Primary
Secondary
Pancreatitis Other Serious 4 Female 1/22/2010 United States
Primary
Secondary
Stem Cell Transplant Required Intervention 6 Male 3/10/2010 Physician United States
Primary
Secondary
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Spinal Compression Fracture Other Serious 7 Female 3/26/2010
Primary
Secondary
Vertigo Hospitalization 15 Male 3/24/2010 Physician Turkey
Primary
Secondary
Concomitant
Swelling Face Other Serious 4 Male 4/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 36 Male 5/27/2010
Primary
Secondary
Sepsis Death 5/24/2010 Netherlands
Primary
Secondary
Therapeutic Agent Toxicity Death 5/24/2010 Netherlands
Primary
Secondary
Platelet Count Decreased Other Serious 4 Female 6/9/2010 Other Health Professional Canada
Primary
Secondary
White Blood Cell Count Increased Other Serious 4 Female 6/17/2010 Other Health Professional Canada
Primary
Secondary
Neuropathy Peripheral Other Serious 2 Male 33 lb 8/2/2010 Other Health Professional Canada
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12 Male 9/2/2010 Other Health Professional Turkey
Primary
Secondary
Concomitant
Hepatitis B Other Serious 57 Female 9/9/2010 Other Health Professional Turkey
Primary
Secondary
Hepatitis B Surface Antigen Positive Required Intervention 57 Female 9/17/2010 Other Health Professional Turkey
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 12 Male 9/23/2010
Primary
Secondary
Testicular Failure Primary Required Intervention 7 Male 10/1/2010 Physician United States
Primary
Secondary
Hepatitis B Hospitalization 57 Female 9/30/2010 Turkey
Primary
Secondary
Hepatitis B Hospitalization 1/1/2010 57 Female 10/15/2010 Other Health Professional Turkey
Primary
Secondary
Therapeutic Response Decreased Hospitalization 5/1/2008 27 Male 11/30/2010
Primary
Secondary
Venous Thrombosis Other Serious 7 Female 12/29/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Neutropenia Hospitalization 121 Male 2/9/2011 Physician United States
Primary
Secondary
Liver Abscess Other Serious 12 Male 2/28/2011 Other Health Professional Brazil
Primary
Secondary
Acute Graft Versus Host Disease Other Serious 3 Male 3/1/2011 Other Health Professional United States
Primary
Concomitant
Acanthamoeba Infection Other Serious 2 Male 3/1/2011 Other Health Professional Austria
Primary
Secondary
Concomitant
Acute Lymphocytic Leukaemia Hospitalization 4/8/2011 10 Male 90 lb 5/11/2011 United States
Primary
Secondary
Hyperviscosity Syndrome Hospitalization 10 Female 6/8/2011 Other Health Professional Spain
Primary
Secondary
Intraocular Pressure Increased Other Serious 5 Female 7/5/2011 Physician Japan
Primary
Secondary
Intraocular Pressure Increased Other Serious 6 Female 7/5/2011 Physician Japan
Primary
Secondary
Strabismus Other Serious 2 Female 7/5/2011 Physician Japan
Primary
Secondary
Osteoporosis Other Serious 6/27/2011 Physician Germany
Primary
Secondary
Headache Other Serious 5 Male 7/7/2011 Other Health Professional Japan
Primary
Secondary
Intraocular Pressure Increased Other Serious 3 Male 7/7/2011 Other Health Professional Japan
Primary
Secondary
Histiocytosis Haematophagic Death 9/16/2011 Physician United States
Primary
Secondary
Cerebral Infarction Death 9/19/2011 Physician United States
Primary
Secondary
Off Label Use Death 9/20/2011 Physician United States
Primary
Secondary
Cerebral Infarction Death 9/22/2011 Physician United States
Primary
Secondary
Enterocolitis Infectious Hospitalization 6/17/2011 22 Female 11/10/2011 Physician United States
Primary
Secondary
Leukoencephalopathy Other Serious 10/26/2011 9 Female 12/14/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Staphylococcal Sepsis Death 22 Female 2/7/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Hypothyroidism Other Serious Male 2/10/2012 Other Health Professional Italy
Primary
Secondary
Hypothyroidism Other Serious Male 2/10/2012 Other Health Professional Italy
Primary
Secondary
Hypothyroidism Other Serious Male 2/10/2012 Other Health Professional Italy
Primary
Secondary
Hypothyroidism Other Serious Female 2/10/2012 Other Health Professional Italy
Primary
Secondary
Hypothyroidism Other Serious Male 2/10/2012 Other Health Professional Italy
Primary
Secondary
Hypothyroidism Other Serious Male 2/10/2012 Other Health Professional Italy
Primary
Secondary
Pruritus Hospitalization 1/11/2012 23 Female 130 lb 2/17/2012 Other Health Professional United States
Primary
Secondary
Nervous System Disorder Death 4/21/2011 16 Male 95 lb 2/17/2012 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 2/17/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 2/17/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 2/17/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 2/17/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 2/17/2012 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/2/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Osteonecrosis Other Serious 2/17/2012 Physician United States
Primary
Secondary
Nervous System Disorder Death 4/21/2011 16 Male 95 lb 3/15/2012 Physician Japan
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious 3/16/2012 Physician Netherlands
Primary
Secondary
Concomitant
Cardiac Failure Death 2/18/2009 10 Female 44 lb 4/5/2012 Consumer Japan
Primary
Secondary
Concomitant

Drug Data