Efavirenz combined with Zidovudine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Abortion Induced Other Serious 5/1/2001 28 Female 1/5/2006 Japan
Primary
Concomitant
Viral Mutation Identified Other Serious Male 12/28/2005 United States
Primary
Secondary
Vomiting Hospitalization 3/1/2005 27 Male 1/9/2006 Other Health Professional Australia
Primary
Secondary
Synovitis Other Serious 8/1/2000 40 Female 1/24/2006 Consumer United Kingdom
Primary
Secondary
Liver Disorder Hospitalization 4/13/2004 Male 1/27/2006 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/8/2001 Male 1/27/2006 Japan
Primary
Secondary
Concomitant
Premature Menopause Other Serious 2/1/1998 36 Female 2/6/2006 Consumer France
Primary
Secondary
Lactic Acidosis Other Serious 8 Male 2/8/2006 Other Health Professional India
Primary
Secondary
Vomiting Other Serious 11/1/2003 29 Female 90 lb 2/10/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Synovitis Other Serious 40 Female 2/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Synovitis Other Serious 40 Female 2/13/2006 Physician
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/1/2004 Male 2/10/2006 Japan
Primary
Secondary
Concomitant
Alopecia Disability 1/24/2006 42 Male 2/21/2006 Consumer United States
Primary
Secondary
Concomitant
Anaemia Other Serious 12/30/2005 46 Male 3/10/2006 Other Health Professional South Africa
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Other Serious 8/12/2005 24 Female 3/17/2006 Consumer South Africa
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/3/2002 Male 3/20/2006 Physician Japan
Primary
Secondary
Concomitant
Viral Load Increased Hospitalization 1/30/2002 44 Male 110 lb 3/22/2006 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 34 Female 3/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 Female 3/31/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 34 Female 3/24/2006 Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/1/2004 Male 4/6/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/3/2002 Male 4/13/2006 Physician Japan
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 37 Male 4/6/2006
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 32 Male 4/10/2006 Brazil
Primary
Secondary
Viral Mutation Identified Other Serious Male 4/19/2006 United States
Primary
Secondary
Pneumonia Other Serious 3/22/2006 Female 84 lb 5/5/2006 Brazil
Primary
Secondary
Concomitant
Oral Candidiasis Other Serious 1/1/2001 Male 198 lb 5/8/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Hypospadias Congenital Anomaly 5/19/2006 Other Health Professional United States
Primary
Secondary
Liver Disorder Hospitalization 4/13/2004 Male 6/1/2006 Japan
Primary
Secondary
Concomitant
Hepatitis C Other Serious Male 6/2/2006 Physician Japan
Primary
Secondary
Concomitant
Nasopharyngeal Cancer Death 8/1/2005 73 Male 6/13/2006 Physician Japan
Primary
Concomitant
Tuberculosis Other Serious 41 Female 6/15/2006 Consumer Brazil
Primary
Secondary
Concomitant
Ultrasound Scan Abnormal Other Serious 9/26/2005 Male 7 lb 6/28/2006 Other Health Professional United States
Primary
Secondary
Hydrocele Congenital Anomaly Male 6 lb 6/30/2006 Other Health Professional United States
Primary
Secondary
Liver Disorder Hospitalization 4/13/2004 Male 6/30/2006 Japan
Primary
Secondary
Concomitant
Hyperlipidaemia Other Serious 9/27/2001 Male 7/7/2006 Physician Japan
Primary
Secondary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 5/2/2000 17 Male 7/10/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 34 Female 7/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ultrasound Scan Abnormal Other Serious 9/26/2005 Male 7 lb 7/11/2006 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Death 56 Male 7/12/2006 Physician Italy
Primary
Concomitant
Weight Decreased Hospitalization 3/10/2000 34 Female 7/10/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 Female 7/19/2006 Physician Japan
Primary
Secondary
Concomitant
Nasopharyngeal Cancer Death 8/1/2005 73 Male 7/21/2006 Physician Japan
Primary
Concomitant
Hyperlipidaemia Hospitalization 2/2/2001 43 Male 7/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Skin Eruption Hospitalization 1/23/2006 Male 7/28/2006 Physician Japan
Primary
Secondary
Concomitant
Tearfulness Life Threatening 7/10/2006 41 Male 153 lb 7/24/2006 Consumer United States
Primary
Secondary
Concomitant
Hydrocele Congenital Anomaly Male 6 lb 7/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ultrasound Scan Abnormal Other Serious 9/26/2005 Male 7 lb 8/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Meconium In Amniotic Fluid Hospitalization Female 6 lb 8/10/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 31 Female 8/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious Male 8/23/2006 Physician Japan
Primary
Secondary
Concomitant
Mitochondrial Toxicity Other Serious 6/1/1998 36 Female 8/18/2006 Physician France
Primary
Concomitant
Hypospadias Congenital Anomaly Male 8/22/2006 Other Health Professional United States
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 49 Female 8/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Von Willebrand's Disease Other Serious 38 Female 9/8/2006 Belgium
Primary
Concomitant
Therapeutic Product Ineffective Other Serious 6 Male 10/6/2006
Primary
Secondary
Hyponatraemia Other Serious 49 Female 10/27/2006 Canada
Primary
Secondary
Concomitant
Interacting
Hypospadias Congenital Anomaly Male 10/27/2006 Other Health Professional United States
Primary
Secondary
Weight Decreased Hospitalization 11/25/2002 Male 11/22/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 12/1/2003 31 Male 11/28/2006 Other Health Professional United States
Primary
Secondary
Immune Reconstitution Syndrome Other Serious 25 Male 11/30/2006 Consumer United States
Primary
Concomitant
Uterine Cyst Hospitalization Female 7 lb 12/12/2006 Consumer France
Primary
Secondary
Concomitant
Vasculitis Cerebral Other Serious 33 Male 12/21/2006 Consumer United States
Primary
Secondary
Gamma-glutamyltransferase Increased Hospitalization 6/1/2004 Male 1/5/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 2/5/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Hospitalisation Hospitalization Female 6 lb 2/7/2007 Other Health Professional United States
Primary
Concomitant
Nodular Regenerative Hyperplasia Hospitalization 39 Male 2/7/2007 Physician France
Primary
Secondary
Pancytopenia Other Serious 9/14/2006 Male 132 lb 2/8/2007 Other Health Professional Belgium
Primary
Secondary
Concomitant
Tachycardia Hospitalization 4/9/2002 23 Male 138 lb 2/9/2007 Physician Japan
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/9/2007 24 Female 90 lb 2/9/2007 Pharmacist United Kingdom
Primary
Concomitant
Tuberculosis Of Central Nervous System Hospitalization 37 Male 2/12/2007 Consumer Argentina
Primary
Secondary
Concomitant
Talipes Other Serious Male 2/16/2007 Other Health Professional South Africa
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 2/22/2007 Physician Japan
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 6/1/2004 Male 3/2/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Female 3/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Electrocardiogram Qt Corrected Interval Prolonged Other Serious 3/16/2007 Other Health Professional Italy
Primary
Interacting
Hepatitis C Other Serious Male 3/16/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/1/2004 Male 3/23/2007 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 3/28/2005 30 Male 3/27/2007 Physician Japan
Primary
Secondary
Trisomy 21 Other Serious 8/4/2006 Male 6 lb 3/27/2007 Other Health Professional United States
Primary
Secondary
Hepatitis B Other Serious 24 Male 5/21/2007 Consumer France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
Talipes Other Serious 9/9/1999 Female 7 lb 6/8/2007 Consumer France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/14/2007 Physician Japan
Primary
Secondary
Concomitant
Lipoatrophy Other Serious 62 Male 6/20/2007 Physician United Kingdom
Primary
Secondary
Uveitis Other Serious 40 Male 6/22/2007 India
Primary
Secondary
Urinary Tract Infection Hospitalization 7/1/2004 Male 6/29/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 5/22/2007 33 Female 99 lb 7/5/2007 Physician South Africa
Primary
Secondary
Leukoencephalopathy Other Serious 40 Female 7/2/2007 Other Health Professional United States
Primary
Secondary
Weight Decreased Hospitalization 11/25/2002 Male 7/11/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 5/2/2000 17 Male 7/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 35 Male 7/17/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 35 Male 7/13/2007 Germany
Primary
Secondary
Urinary Tract Infection Hospitalization 7/1/2004 Male 8/2/2007 Physician Japan
Primary
Secondary
Concomitant
Uveitis Other Serious 40 Male 7/28/2007 Physician India
Primary
Secondary
Uveitis Other Serious 40 Male 8/2/2007
Primary
Secondary
Uveitis Other Serious 40 Male 8/1/2007 Other Health Professional India
Primary
Secondary
Uveitis Other Serious 40 Male 8/3/2007 Physician India
Primary
Secondary
Concomitant
Rash Hospitalization 7/13/2007 4 Male 8/9/2007 Physician Uganda
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Hepatic Steatosis Other Serious 34 Male 8/10/2007 Other Health Professional Brazil
Primary
Secondary
Encephalitis Hospitalization 4/1/2004 43 Male 8/17/2007 United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 9/27/2006 Male 8/22/2007 Japan
Primary
Secondary
Concomitant
Rash Maculo-papular Hospitalization 7/13/2007 4 Male 8/27/2007 Physician Uganda
Primary
Secondary
Concomitant
Liver Disorder Other Serious 1/1/2006 53 Male 8/27/2007 Consumer United States
Primary
Secondary
Concomitant
Nail Pigmentation Other Serious 36 Male 8/30/2007
Primary
Secondary
Premature Baby Congenital Anomaly 1/1/2000 0 Male 9 lb 8/31/2007 Other Health Professional United States
Primary
Secondary
Speech Disorder Other Serious 4/1/2004 43 Male 9/4/2007 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 7/17/2007 5 Female 9/4/2007 Physician Uganda
Primary
Secondary
Concomitant
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Pregnancy Congenital Anomaly Female 7 lb 9/19/2007 Other Health Professional United States
Primary
Secondary
Pregnancy Congenital Anomaly Female 7 lb 9/19/2007 Other Health Professional United States
Primary
Secondary
Rash Maculo-papular Hospitalization 7/13/2007 4 Male 10/5/2007 Physician Uganda
Primary
Secondary
Concomitant
Hepatitis B Death 1/1/2004 24 Male 10/8/2007
Primary
Secondary
Visceral Leishmaniasis Other Serious 3/1/2000 46 Male 10/19/2007 Other Health Professional Italy
Primary
Secondary
Visceral Leishmaniasis Other Serious 3/1/2000 46 Male 10/22/2007 Other Health Professional Italy
Primary
Secondary
Mycobacterium Avium Complex Infection Hospitalization 13 Male 10/12/2007 United States
Primary
Secondary
Concomitant
Pregnancy Other Serious 27 Female 10/26/2007 Other Health Professional Brazil
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 10/29/2007 Physician Japan
Primary
Secondary
Concomitant
Visceral Leishmaniasis Other Serious 10/1/1996 46 Male 11/1/2007
Primary
Secondary
Concomitant
Premature Baby Congenital Anomaly 1/1/2000 0 Male 9 lb 11/2/2007 Other Health Professional United States
Primary
Secondary
Premature Baby Congenital Anomaly 1/1/2000 0 Male 9 lb 11/9/2007 Other Health Professional United States
Primary
Secondary
Small For Dates Baby Other Serious 5/23/2007 Male 11/9/2007 Other Health Professional United States
Primary
Secondary
Hallucination 11/1/2005 59 Female 11/12/2007 Physician United States
Primary
Secondary
Tuberculoid Leprosy Other Serious 30 Male 11/27/2007 Mexico
Primary
Secondary
Tuberculoid Leprosy Other Serious 30 Male 12/5/2007 Consumer Mexico
Primary
Secondary
Cardiomyopathy Other Serious Male 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Cardiomyopathy Other Serious Female 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Encephalopathy Other Serious 4 Male 12/13/2007 Consumer United States
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 2 lb 12/14/2007 Other Health Professional Netherlands
Primary
Secondary
Low Cardiac Output Syndrome Other Serious Male 2 lb 12/14/2007 Other Health Professional Netherlands
Primary
Secondary
Upper Respiratory Tract Infection Death 8/27/2007 63 Male 181 lb 12/14/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 34 Female 12/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 Female 12/19/2007 Physician Japan
Primary
Secondary
Concomitant
Hyperlipidaemia Hospitalization 2/2/2001 43 Male 12/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Premature Baby Other Serious 0 Female 12/21/2007 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Male 12/21/2007 Netherlands
Primary
Secondary
Treatment Failure Other Serious 46 Male 12/18/2007 Switzerland
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 34 Female 12/18/2007 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 Female 12/28/2007 Physician Japan
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Hospitalization 38 Male 12/31/2007 Consumer United States
Primary
Concomitant
Treatment Failure Other Serious 31 Male 12/21/2007 Switzerland
Primary
Secondary
Diarrhoea Hospitalization 12/1/2007 57 Male 1/7/2008 Physician Portugal
Primary
Concomitant
Pyrexia Hospitalization 54 Male 12/28/2007 Brazil
Primary
Secondary
Concomitant
Vomiting Other Serious 27 Male 12/28/2007 Brazil
Primary
Secondary
Concomitant
Vomiting Other Serious 1/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 50 Male 1/23/2008 Physician Italy
Primary
Secondary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Other Serious 50 Male 1/29/2008 Physician Italy
Primary
Secondary
Concomitant
Pancreatitis Haemorrhagic Death 35 Female 197 lb 1/21/2008 Physician United States
Primary
Secondary
Vomiting Life Threatening 4/14/2003 Male 1/30/2008
Primary
Secondary
Concomitant

Drug Data