Efavirenz combined with Stavudine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 7 Male 1/3/2006 Consumer South Africa
Primary
Secondary
Abortion Induced Other Serious 5/1/2001 28 Female 1/5/2006 Japan
Primary
Concomitant
Pyrexia Other Serious 30 Male 1/4/2006 Physician Poland
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 5/31/1999 52 Male 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Sarcoma Hospitalization 1/1/2003 Male 1/18/2006 United States
Primary
Concomitant
Immune Reconstitution Syndrome Other Serious 1/1/2002 2 Female 1/20/2006 Other Health Professional United States
Primary
Concomitant
Viral Infection Hospitalization 12/22/2005 36 Female 114 lb 12/29/2005 United States
Primary
Secondary
Premature Menopause Other Serious 2/1/1998 36 Female 2/6/2006 Consumer France
Primary
Secondary
Lactic Acidosis Other Serious 8 Male 2/8/2006 Other Health Professional India
Primary
Secondary
Lactic Acidosis Other Serious 10 Female 2/8/2006 Other Health Professional India
Primary
Secondary
Renal Failure Hospitalization 10/25/2005 51 Male 2/10/2006 Other Health Professional South Africa
Primary
Secondary
Renal Failure Hospitalization 10/25/2005 51 Male 2/13/2006 Other Health Professional South Africa
Primary
Secondary
Therapy Non-responder Hospitalization 15 Male 2/17/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatitis Hospitalization Male 3/1/2006 Physician United States
Primary
Secondary
Therapy Non-responder Hospitalization 15 Male 2/28/2006 Physician United Kingdom
Primary
Secondary
Gynaecomastia Other Serious 15 Male 3/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Hypertriglyceridaemia Other Serious 12/30/2005 40 Male 3/13/2006 Other Health Professional South Africa
Primary
Secondary
Pancytopenia Other Serious 10/1/1999 Male 3/13/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Other Serious 8/12/2005 24 Female 3/17/2006 Consumer South Africa
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/3/2002 Male 3/20/2006 Physician Japan
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 12/28/2005 35 Male 3/27/2006 Other Health Professional South Africa
Primary
Secondary
Vomiting Hospitalization 3/10/2000 Female 3/31/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/2/2003 36 Male 4/7/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/3/2002 Male 4/13/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/2/2003 36 Male 4/20/2006 Physician Japan
Primary
Secondary
Concomitant
Tumour Haemorrhage Death 1/19/2006 30 Female 4/12/2006 Other Health Professional United States
Primary
Secondary
Hyperlipidaemia 4/30/1998 41 Male 4/21/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/24/2004 39 Female 4/25/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Mycobacterium Kansasii Infection Hospitalization 1/23/2002 27 Female 4/20/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 3/23/2006 30 Female 106 lb 4/27/2006 Physician Uganda
Primary
Secondary
Concomitant
Social Avoidant Behaviour Other Serious 11 Male 64 lb 4/28/2006 Consumer Spain
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/23/2006 30 Female 106 lb 5/1/2006 Physician Uganda
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 58 Male 5/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Uveitis Other Serious 1/27/2005 Female 5/17/2006 Japan
Primary
Secondary
Concomitant
Haemolytic Anaemia Other Serious 9/2/2005 36 Female 5/22/2006 Other Health Professional South Africa
Primary
Secondary
Hepatitis Hospitalization Male 6/1/2006 Other Health Professional Australia
Primary
Secondary
Drug Exposure During Pregnancy Death 41 Female 6/2/2006 Pharmacist South Africa
Primary
Secondary
Hepatitis C Other Serious Male 6/2/2006 Physician Japan
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Death 41 Female 6/16/2006 Other Health Professional South Africa
Primary
Secondary
Viral Mutation Identified Death 11/1/2001 39 Male 6/20/2006
Primary
Secondary
Malaise Other Serious 6/4/1999 Male 6/23/2006 Physician United States
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 5/4/2006 36 Male 7/3/2006 Consumer South Africa
Primary
Secondary
Concomitant
Pancytopenia Other Serious 5/26/1999 41 Male 7/5/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/7/2006 Physician Japan
Primary
Secondary
Concomitant
Hyperlipidaemia Other Serious 9/27/2001 Male 7/7/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/6/2006 46 Male 7/14/2006 Physician Botswana
Primary
Secondary
Hepatitis Death Male 7/17/2006 Physician Brazil
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/19/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 Female 7/19/2006 Physician Japan
Primary
Secondary
Concomitant
Oral Discomfort Other Serious 1/1/2005 42 Female 7/20/2006 Other Health Professional Spain
Primary
Secondary
Thrombocytopenia Other Serious 9/27/2004 Male 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Oral Discomfort Other Serious 1/1/2005 42 Female 7/31/2006 Other Health Professional Spain
Primary
Secondary
Thrombocytopenia Other Serious 9/27/2004 Male 8/4/2006 Physician Japan
Primary
Secondary
Concomitant
Rib Fracture Other Serious 1/6/2004 Female 8/21/2006 Physician Germany
Primary
Concomitant
Pancreatitis Other Serious 7/1/2003 41 Male 8/21/2006 Consumer United States
Primary
Secondary
Shock Other Serious 30 Female 8/23/2006 Other Health Professional Portugal
Primary
Secondary
Mitochondrial Toxicity Other Serious 6/1/1998 36 Female 8/18/2006 Physician France
Primary
Concomitant
Myocarditis Hospitalization 7/1/2002 Male 8/25/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/28/2005 Male 9/7/2006 Physician Japan
Primary
Secondary
Concomitant
Von Willebrand's Disease Other Serious 38 Female 9/8/2006 Belgium
Primary
Concomitant
Sick Sinus Syndrome Other Serious 10/1/1999 Male 9/8/2006 Physician Japan
Primary
Secondary
Concomitant
Productive Cough Other Serious 9/10/2001 Male 9/13/2006 Physician Japan
Primary
Secondary
Concomitant
Vasodilatation Life Threatening 10/24/2001 Male 9/13/2006 Physician Japan
Primary
Secondary
Concomitant
Walking Disability Other Serious 10/14/1996 Male 9/14/2006 Physician Japan
Primary
Secondary
Concomitant
Lipohypertrophy Other Serious 9/26/2002 Male 9/14/2006 Japan
Primary
Secondary
Concomitant
Lipohypertrophy Other Serious 9/26/2002 Male 9/25/2006 Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 9/19/2006 Male 143 lb 9/29/2006 Physician Austria
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 9/13/2006 34 Female 265 lb 10/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9 Female 10/6/2006
Primary
Secondary
Concomitant
Therapeutic Product Ineffective Other Serious 6 Male 10/6/2006
Primary
Secondary
Muscle Atrophy Other Serious 7/15/2006 10/9/2006 Physician Botswana
Primary
Secondary
Pleural Effusion Death 34 Female 10/12/2006 Consumer South Africa
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/28/2005 Male 10/12/2006 Physician United States
Primary
Secondary
Concomitant
Glucose Tolerance Impaired Other Serious 9/22/2004 Male 10/12/2006 Physician Japan
Primary
Secondary
Concomitant
Lymph Node Tuberculosis Other Serious 12 Male 10/6/2006 India
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/19/2006 Male 143 lb 10/16/2006 Physician Austria
Primary
Secondary
Concomitant
Lactic Acidosis Hospitalization 36 Female 287 lb 10/16/2006 Other Health Professional South Africa
Primary
Secondary
Concomitant
Pleural Effusion Death 34 Female 10/11/2006 South Africa
Primary
Secondary
Concomitant
Lactic Acidosis Other Serious 45 Female 165 lb 10/23/2006 Other Health Professional South Africa
Primary
Secondary
Lactic Acidosis Other Serious 36 Female 128 lb 10/23/2006 Other Health Professional South Africa
Primary
Secondary
Lactic Acidosis Other Serious 39 Female 214 lb 10/23/2006 Other Health Professional South Africa
Primary
Secondary
Lactic Acidosis Other Serious 35 Female 181 lb 10/23/2006 Other Health Professional South Africa
Primary
Secondary
Lactic Acidosis Other Serious 35 Female 126 lb 10/23/2006 Other Health Professional South Africa
Primary
Secondary
Lactic Acidosis Other Serious 34 Female 181 lb 10/23/2006 Other Health Professional South Africa
Primary
Secondary
Lactic Acidosis Other Serious 32 Female 148 lb 10/23/2006 Other Health Professional South Africa
Primary
Secondary
Lactic Acidosis Other Serious 35 Female 183 lb 10/23/2006 Other Health Professional South Africa
Primary
Secondary
Lactic Acidosis Other Serious 37 Female 309 lb 10/23/2006 Other Health Professional South Africa
Primary
Secondary
Lactic Acidosis Other Serious 37 Female 227 lb 10/23/2006 Other Health Professional South Africa
Primary
Secondary
Lactic Acidosis Other Serious 36 Female 154 lb 10/23/2006 Other Health Professional South Africa
Primary
Secondary
Lactic Acidosis Other Serious 55 Female 174 lb 10/23/2006 Other Health Professional South Africa
Primary
Secondary
Productive Cough Other Serious 9/10/2001 Male 10/27/2006 Physician Japan
Primary
Secondary
Concomitant
Hemiparesis Other Serious 3/18/2004 66 Female 10/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperlipidaemia Other Serious 7/1/2002 Male 11/1/2006 Physician Japan
Primary
Secondary
Concomitant
Talipes Other Serious 11/1/2005 11/3/2006 Consumer South Africa
Primary
Concomitant
Syncope Hospitalization 9/19/2006 Male 143 lb 11/3/2006 Physician Austria
Primary
Secondary
Concomitant
Primary Adrenal Insufficiency Hospitalization 12/1/2005 61 Male 11/4/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Infarction Hospitalization 4/28/2005 Male 11/9/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Death 2/15/2001 Male 11/13/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Death 2/15/2001 Male 11/13/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Death 2/15/2001 Male 11/13/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Death 2/15/2001 Male 11/13/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Death 2/15/2001 Male 11/13/2006 Physician Japan
Primary
Secondary
Concomitant
Non-hodgkin's Lymphoma Other Serious 34 Female 11/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/19/2006 43 Male 143 lb 11/17/2006 Physician Austria
Primary
Secondary
Concomitant
Pulmonary Infarction Other Serious 4/28/2005 Male 11/17/2006 Physician United States
Primary
Secondary
Concomitant
Lipoatrophy Other Serious 8/31/2006 Female 11/22/2006 Physician Botswana
Primary
Secondary
Talipes Other Serious 11/1/2005 11/22/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 11/22/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Syncope Hospitalization 9/19/2006 43 Male 143 lb 11/30/2006 Physician Austria
Primary
Secondary
Concomitant
Weight Decreased Death 9/23/2006 21 Female 121 lb 11/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 38 Female 121 lb 12/8/2006 Other Health Professional Spain
Primary
Concomitant
Uterine Cyst Hospitalization Female 7 lb 12/12/2006 Consumer France
Primary
Secondary
Concomitant
Lipodystrophy Acquired Other Serious 4/1/2006 54 Female 12/13/2006 Other Health Professional South Africa
Primary
Secondary
Concomitant
Renal Failure Acute Death 6/17/2005 51 Male 12/14/2006 Physician Japan
Primary
Concomitant
Nightmare Hospitalization 7/14/2006 60 Male 12/21/2006 Consumer United States
Primary
Secondary
Hydronephrosis Congenital Anomaly 10/2/2006 12/26/2006 Other Health Professional United States
Primary
Secondary
Sick Sinus Syndrome Other Serious 10/1/1999 Male 12/29/2006 Physician Japan
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2005 Male 1/5/2007 Physician United States
Primary
Secondary
Concomitant
Sexual Dysfunction Male 8/16/2006 United States
Primary
Concomitant
Vasculitis Other Serious 5/21/2004 37 Female 1/11/2007 Consumer Chile
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2005 Male 1/12/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Death 12/17/2006 50 Male 116 lb 1/16/2007 Consumer United States
Primary
Secondary
Concomitant
Stress Other Serious 1/10/2006 1/24/2007 Physician Botswana
Primary
Secondary
Small For Dates Baby Other Serious 6/21/2006 0 Male 1/24/2007 Physician South Africa
Primary
Concomitant
Neutropenia Other Serious 1/1/2004 Male 1/25/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Glucose Tolerance Impaired Other Serious 9/22/2004 Male 1/25/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/28/1999 Male 1/25/2007 Physician Japan
Primary
Secondary
Concomitant
Lipodystrophy Acquired Other Serious 12/15/2006 29 Female 2/5/2007 Physician Botswana
Primary
Secondary
Weight Decreased Hospitalization 11/25/2002 Male 2/5/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Nodular Regenerative Hyperplasia Hospitalization 39 Male 2/7/2007 Physician France
Primary
Secondary
Lactic Acidosis Hospitalization 36 Female 2/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 56 Male 126 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 40 Male 134 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Tachycardia Hospitalization 4/9/2002 23 Male 138 lb 2/9/2007 Physician Japan
Primary
Secondary
Concomitant
Hydronephrosis Congenital Anomaly 10/2/2006 2/15/2007 Other Health Professional United States
Primary
Secondary
Renal Failure Acute Death 6/17/2005 51 Male 2/15/2007 Physician Japan
Primary
Concomitant
Kidney Transplant Rejection Other Serious Female 2/8/2007 South Africa
Primary
Secondary
Concomitant
Talipes Other Serious Male 2/16/2007 Other Health Professional South Africa
Primary
Secondary
Concomitant
Glucose Tolerance Impaired Other Serious 9/22/2004 Male 2/22/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 2/22/2007 Physician Japan
Primary
Secondary
Concomitant
Primary Adrenal Insufficiency Hospitalization 12/1/2005 61 Male 3/7/2007 Physician Japan
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 7/7/2006 Male 3/14/2007 Physician Austria
Primary
Secondary
Concomitant
Sudden Death Death 36 Female 134 lb 3/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Death 42 Female 3/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis C Other Serious Male 3/16/2007 Physician Japan
Primary
Secondary
Concomitant
Productive Cough Other Serious 9/10/2001 Male 3/16/2007 Physician Japan
Primary
Secondary
Concomitant
Hydronephrosis Other Serious 10/2/2006 Male 4/2/2007 Other Health Professional United States
Primary
Secondary
Glucose Tolerance Impaired Other Serious 9/22/2004 Male 4/5/2007 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/7/2007 36 Female 4/24/2007 Other Health Professional Botswana
Primary
Secondary
Lactic Acidosis Death 4/30/2007 Other Health Professional United States
Primary
Secondary

Drug Data