Efavirenz combined with Ritonavir

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Tubular Necrosis Hospitalization 61 Male 1/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 5/31/1999 52 Male 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 52 Male 1/20/2006 United States
Primary
Concomitant
Liver Disorder Hospitalization 4/13/2004 Male 1/27/2006 Japan
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Life Threatening 7/1/2005 36 Unknown 2/17/2006 United Kingdom
Primary
Concomitant
Tachycardia Other Serious 62 Female 3/1/2006 Consumer Australia
Primary
Concomitant
Vomiting Hospitalization 3/10/2000 34 Female 3/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/1/2006 45 Female 4/21/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 2/1/2006 45 Female 4/27/2006 Physician United States
Primary
Secondary
Concomitant
Oral Candidiasis Other Serious 1/1/2001 Male 198 lb 5/8/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Tachycardia Other Serious 2/17/2006 62 Female 121 lb 5/15/2006 Consumer Australia
Primary
Concomitant
Liver Disorder Hospitalization 4/13/2004 Male 6/1/2006 Japan
Primary
Secondary
Concomitant
Lethargy Hospitalization 2/21/2006 45 Female 6/19/2006 Consumer United States
Primary
Concomitant
Liver Disorder Hospitalization 4/13/2004 Male 6/30/2006 Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 34 Female 7/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 4/25/2006 46 Male 137 lb 7/10/2006 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/10/2000 34 Female 7/10/2006 Physician Japan
Primary
Secondary
Concomitant
Rash Hospitalization 5/29/2006 28 Female 7/28/2006 Physician Spain
Primary
Concomitant
Nausea Hospitalization 49 Female 7/24/2006 United States
Primary
Secondary
Concomitant
Vasodilatation Life Threatening 10/24/2001 Male 9/13/2006 Physician Japan
Primary
Secondary
Concomitant
Nephrolithiasis Other Serious 1/4/2006 64 Male 146 lb 9/29/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hyponatraemia Other Serious 49 Female 10/27/2006 Canada
Primary
Secondary
Concomitant
Interacting
Vertigo Other Serious 38 Female 11/22/2006 Other Health Professional Spain
Primary
Concomitant
Rash Erythematous Hospitalization 3/6/2001 39 12/1/2006 Consumer France
Primary
Secondary
Vomiting Other Serious 38 Female 121 lb 12/8/2006 Other Health Professional Spain
Primary
Concomitant
Uterine Cyst Hospitalization Female 7 lb 12/12/2006 Consumer France
Primary
Secondary
Concomitant
Haemolytic Anaemia Other Serious 1/1/2006 Female 12/18/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 1/1/2004 Male 12/29/2006 Physician Australia
Primary
Secondary
Concomitant
Haemolytic Anaemia Other Serious 1/1/2006 Female 1/4/2007 Consumer United States
Primary
Secondary
Concomitant
Meningitis Aseptic Hospitalization 8/1/2006 44 Male 1/19/2007 Physician United States
Primary
Concomitant
General Physical Health Deterioration Other Serious 9/22/2006 Male 1/19/2007 Physician Chile
Primary
Concomitant
Renal Colic Other Serious 10/1/2005 38 Male 154 lb 1/22/2007 Physician France
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious Male 1/23/2007 Pharmacist United Kingdom
Primary
Concomitant
Cerebrovascular Accident Other Serious Male 1/25/2007 Pharmacist United Kingdom
Primary
Concomitant
Neutropenia Other Serious 1/1/2004 Male 1/25/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Other Serious Male 1/29/2007 Pharmacist United Kingdom
Primary
Concomitant
Nodular Regenerative Hyperplasia Hospitalization 39 Male 2/7/2007 Physician France
Primary
Secondary
Nephropathy Toxic Other Serious 56 Male 126 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 48 Male 132 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 51 Female 108 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 40 Male 134 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Primary Adrenal Insufficiency Hospitalization 12/1/2005 61 Male 3/7/2007 Physician Japan
Primary
Secondary
Concomitant
Meningitis Aseptic Hospitalization 8/1/2006 Male 156 lb 3/19/2007 Physician United States
Primary
Concomitant
Pulmonary Hypertension Life Threatening 3/18/2000 24 Male 5/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Paraparesis Other Serious 5/14/2007 54 Female 5/25/2007 Consumer Botswana
Primary
Secondary
Hepatitis B Other Serious 24 Male 5/25/2007 France
Primary
Secondary
Concomitant
Pulmonary Hypertension Life Threatening 3/18/2000 24 Male 6/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Talipes Other Serious 9/9/1999 Female 7 lb 6/8/2007 Consumer France
Primary
Secondary
Concomitant
Hepatic Cirrhosis Hospitalization 4/25/2005 39 Male 6/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Uveitis Hospitalization 9/15/2006 44 Female 7/20/2007 Consumer France
Primary
Secondary
Concomitant
Hepatic Steatosis Other Serious 34 Male 8/10/2007 Other Health Professional Brazil
Primary
Secondary
Pyrexia Other Serious 7/3/2007 69 Male 161 lb 8/22/2007 Physician Spain
Primary
Secondary
Concomitant
Wrist Fracture Hospitalization 6/30/2007 Male 8/31/2007 Physician Denmark
Primary
Secondary
Concomitant
Calculus Urinary Hospitalization 47 Male 9/5/2007 Other Health Professional France
Primary
Secondary
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Calculus Urinary Hospitalization 47 Male 9/13/2007 Other Health Professional France
Primary
Secondary
Renal Failure Acute Hospitalization 8/1/2006 51 Male 7/13/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 7/5/2007 69 Male 161 lb 9/20/2007 Physician Spain
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/15/2007 Male 9/28/2007 Other Health Professional France
Primary
Concomitant
Visceral Leishmaniasis Other Serious 3/1/2000 46 Male 10/19/2007 Other Health Professional Italy
Primary
Secondary
Visceral Leishmaniasis Other Serious 3/1/2000 46 Male 10/22/2007 Other Health Professional Italy
Primary
Secondary
Vitamin D Deficiency Hospitalization 1/1/2005 Male 117 lb 10/24/2007 Other Health Professional France
Primary
Secondary
Concomitant
Visceral Leishmaniasis Other Serious 10/1/1996 46 Male 11/1/2007
Primary
Secondary
Concomitant
Liver Disorder Other Serious 36 Male 11/19/2007 Consumer United States
Primary
Secondary
Premature Rupture Of Membranes Other Serious Female 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Cardiomyopathy Other Serious Male 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Cardiomyopathy Other Serious Female 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Drug Exposure During Pregnancy Other Serious Female 2 lb 12/14/2007 Other Health Professional Netherlands
Primary
Secondary
Low Cardiac Output Syndrome Other Serious Male 2 lb 12/14/2007 Other Health Professional Netherlands
Primary
Secondary
Vomiting Hospitalization 3/10/2000 34 Female 12/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Premature Baby Other Serious 0 Female 12/21/2007 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Male 12/21/2007 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Female 2/18/2008 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Male 2/18/2008 Netherlands
Primary
Secondary
Hepatic Function Abnormal Hospitalization 5/31/1999 52 Male 2/27/2008 Physician United States
Primary
Secondary
Concomitant
Lipoatrophy Other Serious 55 Male 3/5/2008 Physician Spain
Primary
Secondary
Hepatitis Other Serious 1/17/2008 Male 3/6/2008 Physician Hong Kong
Primary
Secondary
Concomitant
Premature Baby Other Serious 0 Female 3/14/2008 Netherlands
Primary
Secondary
Premature Baby Other Serious 0 Male 3/14/2008 Netherlands
Primary
Secondary
Suicidal Ideation Other Serious 8/16/2006 Male 194 lb 3/17/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 8/16/2006 Male 194 lb 3/20/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Lipoatrophy Other Serious 55 Male 3/18/2008 Spain
Primary
Secondary
Suicidal Ideation Other Serious 8/16/2006 Male 194 lb 4/10/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Haematoma Hospitalization 2/3/2008 32 Male 4/10/2008 Other Health Professional France
Primary
Secondary
Histoplasmosis Hospitalization 4/15/2008 Male 141 lb 4/24/2008 Brazil
Primary
Concomitant
Haemolytic Anaemia Other Serious 1/1/2006 Female 4/28/2008 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 34 Female 4/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Haematoma Hospitalization 2/3/2008 32 Male 5/1/2008 Other Health Professional France
Primary
Secondary
Osteonecrosis Disability 10/1/2007 Male 194 lb 5/23/2008 Physician Belgium
Primary
Secondary
Concomitant
Hepatitis Other Serious 1/17/2008 Male 5/27/2008 Physician Hong Kong
Primary
Secondary
Concomitant
Death Death 5/15/2008 44 Male 5/28/2008 Physician Peru
Primary
Concomitant
Haematoma Hospitalization 2/3/2008 32 Male 6/4/2008 Other Health Professional France
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 6/21/2007 26 Female 7/10/2008 Other Health Professional Uganda
Primary
Secondary
Lipodystrophy Acquired Other Serious 13 Female 7/30/2008 Consumer Spain
Primary
Secondary
Uveitis Hospitalization 9/15/2006 44 Female 8/6/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious 6/11/2007 45 Male 8/11/2008 Physician United States
Primary
Secondary
Concomitant
Uterine Disorder Death 2/1/2007 3 lb 8/13/2008 Physician Germany
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/11/2007 45 Male 8/13/2008 Physician United States
Primary
Secondary
Concomitant
Pregnancy Congenital Anomaly Female 8/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Pregnancy Congenital Anomaly Female 8/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Rash Other Serious 39 Male 9/11/2008 Other Health Professional United States
Primary
Secondary
Tearfulness Other Serious 6/2/2006 44 Male 9/11/2008 Physician Canada
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 22 Male 9/12/2008 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 9/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 46 Male 9/17/2008 Other Health Professional United States
Primary
Secondary
Therapeutic Response Decreased Other Serious 47 Male 9/17/2008 Other Health Professional United States
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 22 Male 9/17/2008 United States
Primary
Secondary
Concomitant
Respiratory Failure Death Male 10/22/2008 Consumer United States
Primary
Secondary
Weight Increased Other Serious Male 195 lb 10/17/2008 United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Other Serious Male 10/29/2008
Primary
Secondary
Suicidal Ideation Other Serious 8/16/2006 42 Male 194 lb 10/30/2008 Consumer Australia
Primary
Secondary
Concomitant
Blood Hiv Rna Increased Other Serious Male 10/31/2008 Other Health Professional United States
Primary
Secondary
Drug Resistance Other Serious 11/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Vaginitis Gardnerella Other Serious 5/1/2008 41 Female 11/6/2008 Other Health Professional France
Primary
Secondary
Respiratory Failure Death Male 11/12/2008 Consumer United States
Primary
Secondary
Peripheral Sensory Neuropathy Other Serious 46 Male 11/14/2008 United States
Primary
Secondary
Ophthalmoplegia Other Serious 47 Male 11/14/2008 United States
Primary
Secondary
Concomitant
Haematoma Hospitalization 2/3/2008 32 Male 12/4/2008 Other Health Professional France
Primary
Secondary
Urogenital Disorder Congenital Anomaly 12/19/2008 Physician Germany
Primary
Secondary
Off Label Use Other Serious Male 12/27/2008 Physician Argentina
Primary
Secondary
Concomitant
Interacting
Liver Function Test Abnormal Other Serious 40 Male 1/9/2009
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 11/20/2008 Male 137 lb 1/16/2009 Physician Portugal
Primary
Concomitant
Stress Hospitalization 41 Male 2/4/2009 Consumer United States
Primary
Secondary
Neuropathy Peripheral Other Serious 11/20/2008 Male 137 lb 2/6/2009 Physician Portugal
Primary
Concomitant
Renal Failure Acute Other Serious 3/26/2008 2/18/2009 Physician Brazil
Primary
Concomitant
Respiratory Failure Death Male 2/23/2009 Consumer United States
Primary
Secondary
Somnambulism Life Threatening 12/1/2008 31 Male 2/18/2009 United Kingdom
Primary
Concomitant
Somnambulism Life Threatening 12/1/2008 31 Male 165 lb 2/20/2009 Consumer Denmark
Primary
Secondary
Concomitant
Somnambulism Life Threatening 12/1/2008 31 Male 165 lb 2/18/2009 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Acute Other Serious 3/26/2008 2/27/2009 Physician Brazil
Primary
Concomitant
Somnambulism Life Threatening 12/1/2008 31 Male 2/23/2009 Other Health Professional United Kingdom
Primary
Concomitant
Somnambulism Life Threatening 12/1/2008 31 Male 165 lb 2/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Uterine Disorder Death 2/1/2007 3 lb 3/3/2009 Physician Germany
Primary
Secondary
Concomitant
Somnambulism Life Threatening 12/1/2008 31 Male 165 lb 2/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Somnambulism Life Threatening 12/1/2008 31 Male 2/28/2009 United Kingdom
Primary
Concomitant
Protein-losing Gastroenteropathy Other Serious 3/1/2008 Male 154 lb 3/17/2009 Physician Japan
Primary
Secondary
Concomitant
Protein-losing Gastroenteropathy Other Serious 3/1/2008 Male 154 lb 3/23/2009 Physician Japan
Primary
Secondary
Concomitant
Pregnancy Other Serious 38 Female 3/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Injection Site Reaction Other Serious 38 Female 3/26/2009 Physician Nigeria
Primary
Secondary
Pregnancy Other Serious 38 Female 3/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Injection Site Reaction Other Serious 38 Female 3/30/2009 Other Health Professional
Primary
Secondary
Lipodystrophy Acquired Other Serious 40 Male 4/15/2009 Other Health Professional United States
Primary
Secondary
Stress Hospitalization 41 Male 4/16/2009 Consumer United States
Primary
Secondary
Stress Hospitalization 41 Male 4/16/2009 Consumer United States
Primary
Secondary
Weight Gain Poor Other Serious 2 Male 4/16/2009 South Africa
Primary
Secondary
Cardiomyopathy Hospitalization 3/4/2009 50 Male 134 lb 5/26/2009 Consumer Australia
Primary
Secondary
Paraesthesia Other Serious 1/1/2009 44 Male 6/5/2009 Pharmacist Ireland
Primary
Concomitant
Nodular Regenerative Hyperplasia Other Serious 5/1/2007 38 Female 6/10/2009 Other Health Professional France
Primary
Secondary
Vitamin B12 Deficiency Other Serious 44 Male 6/12/2009 Pharmacist Ireland
Primary
Concomitant
Nodular Regenerative Hyperplasia Other Serious 6/19/2009 Consumer France
Primary
Secondary

Drug Data