Efavirenz combined with Raltegravir

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Haematoma Hospitalization 2/3/2008 Male 4/10/2008 Other Health Professional France
Primary
Secondary
Respiratory Failure Death 7/14/2008 Male 7/30/2008 Physician Japan
Primary
Secondary
Respiratory Failure Death 7/1/2008 39 Male 8/1/2008 Physician United States
Primary
Secondary
Meningitis Cryptococcal Hospitalization 7/19/2005 Male 8/4/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death 7/1/2008 39 Male 8/8/2008 Consumer United States
Primary
Secondary
Myalgia Hospitalization 9/7/2001 Male 8/28/2008 Physician Japan
Primary
Secondary
Concomitant
Meningitis Cryptococcal Hospitalization 7/19/2005 Male 9/23/2008 Physician Japan
Primary
Secondary
Concomitant
Myalgia Hospitalization 9/7/2001 Male 10/2/2008 Japan
Primary
Secondary
Concomitant
Respiratory Failure Death Male 10/22/2008 Consumer United States
Primary
Secondary
Respiratory Failure Death Male 10/28/2008 Consumer United States
Primary
Secondary
Meningitis Cryptococcal Hospitalization 7/19/2005 Male 11/7/2008 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Death Male 11/12/2008 Consumer United States
Primary
Secondary
Respiratory Failure Death Male 11/13/2008 Consumer United States
Primary
Secondary
Bone Marrow Failure Life Threatening 9/21/2008 12/10/2008 Other Health Professional France
Primary
Secondary
Concomitant
Haematoma Hospitalization 2/3/2008 Male 12/11/2008 Other Health Professional France
Primary
Secondary
Drug Interaction Other Serious 54 Male 12/31/2008 Other Health Professional Canada
Primary
Secondary
Interacting
Stress Hospitalization 41 Male 2/4/2009 Consumer United States
Primary
Secondary
Respiratory Failure Death Male 2/23/2009 Consumer United States
Primary
Secondary
Respiratory Failure Death Male 2/26/2009 Consumer United States
Primary
Secondary
Respiratory Failure Death Male 2/27/2009 Consumer United States
Primary
Secondary
Ventricular Tachycardia Other Serious 47 Female 3/4/2009
Primary
Secondary
Concomitant
Respiratory Failure Death Male 3/12/2009 Consumer United States
Primary
Secondary
Respiratory Failure Death Male 3/12/2009 Consumer United States
Primary
Secondary
Transplant Rejection Other Serious 9 Male 3/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Respiratory Failure Death Male 3/18/2009 Consumer United States
Primary
Secondary
Transplant Rejection Other Serious 9 Male 3/30/2009 Other Health Professional Nigeria
Primary
Secondary
Renal Disorder Hospitalization 9 Male 3/24/2009
Primary
Secondary
Transplant Rejection Other Serious 9 Male 3/30/2009 United Kingdom
Primary
Secondary
Transplant Rejection Other Serious 1/1/2008 9 Male 4/2/2009 United Kingdom
Primary
Secondary
Transplant Rejection Hospitalization 9 Male 4/6/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Interacting
Renal Impairment Hospitalization 9 Male 3/31/2009 United Kingdom
Primary
Secondary
Concomitant
Stress Hospitalization 41 Male 4/16/2009 Consumer United States
Primary
Secondary
Stress Hospitalization 41 Male 4/16/2009 Consumer United States
Primary
Secondary
Transplant Rejection Hospitalization 9 Male 4/22/2009 Physician United Kingdom
Primary
Concomitant
Interacting
Transplant Rejection Hospitalization 9 Male 5/1/2009 Physician United Kingdom
Primary
Concomitant
Interacting
Transplant Rejection Other Serious 9 Male 5/8/2009 Other Health Professional Nigeria
Primary
Secondary
Vitamin B12 Deficiency Other Serious 44 Male 6/12/2009 Pharmacist Ireland
Primary
Concomitant
Paraesthesia Other Serious 3/25/2009 27 Male 112 lb 6/22/2009 Consumer United States
Primary
Concomitant
Paraesthesia Disability 12/10/2008 Male 7/20/2009 Pharmacist Ireland
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 47 Female 7/22/2009 Other Health Professional United States
Primary
Interacting
Ventricular Tachycardia Other Serious 47 Female 7/27/2009 Other Health Professional United States
Primary
Interacting
Vitamin B12 Deficiency Other Serious 12/10/2008 Male 7/29/2009 Pharmacist Ireland
Primary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 7/31/2009
Primary
Secondary
Transplant Rejection Other Serious 9 Male 8/12/2009 Other Health Professional United States
Primary
Secondary
Hyperlipidaemia Hospitalization Male 8/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperlipidaemia Hospitalization Male 8/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Stress Hospitalization 41 Male 8/13/2009 Consumer United States
Primary
Secondary
Transplant Rejection Other Serious 9 Male 8/17/2009 Other Health Professional United States
Primary
Secondary
Lymphoma Life Threatening 12/1/2007 Male 8/24/2009 Japan
Primary
Secondary
Concomitant
Lymphoma Life Threatening 12/1/2007 Male 8/26/2009 Japan
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 9/8/2009 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 9/17/2009 Other Health Professional Canada
Primary
Secondary
Myalgia Hospitalization 9/7/2001 Male 9/18/2009 Japan
Primary
Secondary
Concomitant
Ophthalmoplegia Other Serious 52 Male 9/23/2009 Other Health Professional Canada
Primary
Secondary
Subdural Haematoma Hospitalization 9/1/2008 Male 9/23/2009 Japan
Primary
Secondary
Concomitant
Ophthalmoplegia Other Serious 52 Male 9/29/2009 Other Health Professional Canada
Primary
Secondary
Vitamin B12 Deficiency Other Serious 12/10/2008 Male 10/1/2009 Pharmacist Ireland
Primary
Concomitant
Paraesthesia Disability 12/10/2008 Male 10/2/2009 Pharmacist Ireland
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 9/1/2008 Male 10/5/2009 Japan
Primary
Secondary
Concomitant
Parkinsonism Other Serious 44 Male 10/8/2009 Other Health Professional Australia
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 10/7/2009
Primary
Secondary
Stevens-johnson Syndrome Other Serious 1/1/2009 40 Female 10/14/2009 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 10/19/2009 Other Health Professional Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 10/22/2009 Physician United States
Primary
Secondary
Subdural Haematoma Hospitalization Male 11/13/2009 Consumer United States
Primary
Secondary
Concomitant
Subdural Haematoma Hospitalization 9/1/2008 Male 11/23/2009 Japan
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 11/24/2009 Other Health Professional United States
Primary
Secondary
Myalgia Hospitalization 9/7/2001 Male 11/25/2009 Japan
Primary
Secondary
Concomitant
Urine Colour Abnormal Other Serious 7/6/2007 9 Male 1/5/2010 Other Health Professional Nigeria
Primary
Secondary
Nephrolithiasis Other Serious 4/1/2009 40 Male 1/7/2010 Other Health Professional Switzerland
Primary
Secondary
Nephrolithiasis Other Serious 4/1/2009 48 Male 1/11/2010 Other Health Professional Switzerland
Primary
Secondary
Subdural Haematoma Hospitalization 9/1/2008 Male 1/12/2010 Japan
Primary
Secondary
Concomitant
Lymphoma Life Threatening 12/1/2007 Male 1/18/2010 Japan
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 10 Male 2/8/2010 Other Health Professional United Kingdom
Primary
Secondary
Subdural Haematoma Hospitalization Male 2/18/2010 Consumer United States
Primary
Secondary
Concomitant
Parkinsonism Other Serious 44 Male 3/4/2010 Consumer United States
Primary
Secondary
Parkinsonism Other Serious 44 Male 3/17/2010 Consumer Australia
Primary
Secondary
Lymphoma Life Threatening 12/1/2007 Male 3/17/2010 Japan
Primary
Secondary
Concomitant
Asthmatic Crisis Other Serious Male 4/9/2010 Other Health Professional France
Primary
Concomitant
Alanine Aminotransferase Increased Life Threatening 4/27/2010 41 Male 146 lb 5/10/2010 Thailand
Primary
Concomitant
Rash Other Serious 5/1/2005 34 Female 5/17/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Alanine Aminotransferase Increased Life Threatening 4/27/2010 41 Male 146 lb 5/19/2010 Thailand
Primary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 Male 5/24/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/28/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/28/2010 Physician United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 6/3/2010 United States
Primary
Secondary
Alanine Aminotransferase Increased Life Threatening 4/27/2010 41 Male 146 lb 6/3/2010 Thailand
Primary
Concomitant
Gamma-glutamyltransferase Increased Life Threatening 5/25/2010 41 Male 148 lb 6/4/2010 Thailand
Primary
Concomitant
Gamma-glutamyltransferase Increased Life Threatening 5/25/2010 41 Male 148 lb 6/8/2010 Thailand
Primary
Secondary
Concomitant
Rash Maculo-papular Life Threatening 5/25/2010 41 Male 148 lb 6/16/2010 Thailand
Primary
Secondary
Concomitant
Nephrotic Syndrome Other Serious 5/1/2010 6/23/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Required Intervention 52 Male 6/14/2010 Other Health Professional United States
Primary
Secondary
Vitamin B12 Deficiency Disability 1/15/2010 26 Male 7/12/2010 Physician Japan
Primary
Secondary
Vitamin B12 Deficiency Hospitalization 1/1/2010 26 Male 7/14/2010 Consumer United States
Primary
Secondary
Drug Interaction Other Serious 54 Male 7/15/2010 Consumer United States
Primary
Interacting
Vitamin B12 Deficiency Disability 1/15/2010 26 Male 7/21/2010 Physician Japan
Primary
Secondary
Alanine Aminotransferase Increased Life Threatening 4/27/2010 41 Male 150 lb 7/22/2010 Thailand
Primary
Concomitant
Vitamin B12 Deficiency Disability 1/15/2010 26 Male 8/19/2010 Physician Japan
Primary
Secondary
Peripheral Ischaemia Hospitalization 8/9/2010 14 Female 8/27/2010 Pharmacist Portugal
Primary
Concomitant
Peripheral Ischaemia Hospitalization 8/9/2010 14 Female 9/3/2010 Pharmacist Portugal
Primary
Concomitant
Gamma-glutamyltransferase Increased Life Threatening 5/25/2010 41 Male 148 lb 9/8/2010 Thailand
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 2/1/2009 68 Male 117 lb 10/4/2010 Physician Finland
Primary
Secondary
Concomitant
Vomiting Hospitalization 43 Female 10/7/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Lymphoma Life Threatening 12/1/2007 62 Male 11/3/2010 Physician Japan
Primary
Secondary
Concomitant
Transplant Rejection Other Serious 9 Male 11/16/2010 Other Health Professional United States
Primary
Secondary
Viral Myositis Other Serious 2/1/2009 68 Male 117 lb 11/16/2010 Physician Finland
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 2/1/2009 68 Male 117 lb 11/24/2010 Physician Finland
Primary
Secondary
Concomitant
Urine Colour Abnormal Life Threatening 7/6/2007 9 Male 11/29/2010 Other Health Professional Nigeria
Primary
Secondary
Aphasia Hospitalization 11/13/2006 55 Male 2/7/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Neurodegenerative Disorder Other Serious 11/13/2006 55 Male 2/17/2011 Physician Germany
Primary
Secondary
Concomitant
Hyperlactacidaemia Life Threatening Male 2/18/2011 Consumer United States
Primary
Secondary
Concomitant
Hepatic Encephalopathy Other Serious 10 Male 3/1/2011 United Kingdom
Primary
Secondary
Disorientation Other Serious 11/13/2006 55 Male 3/10/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 11/13/2006 55 Male 3/18/2011 Physician Germany
Primary
Secondary
Concomitant
Polymyositis Disability 78 Male 3/25/2011 Physician Italy
Primary
Concomitant
Hyperhidrosis 33 Male 6/6/2011 Consumer United States
Primary
Secondary
Concomitant
Hyperlipidaemia Hospitalization 4/1/1998 41 Male 7/14/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Resistance Other Serious 42 Male 8/18/2011 Other Health Professional Japan
Primary
Secondary
Renal Tubular Disorder Other Serious 2/22/2011 51 Male 8/30/2011 Physician United States
Primary
Secondary
Renal Tubular Disorder Other Serious 2/22/2011 51 Male 8/31/2011 Physician Switzerland
Primary
Secondary
Concomitant
Psychiatric Symptom Other Serious 42 Male 10/3/2011 Other Health Professional Japan
Primary
Secondary
Sepsis Hospitalization 6/1/2008 Female 10/21/2011 Physician Romania
Primary
Secondary
Concomitant
Arteriosclerosis Other Serious 1/1/2010 31 Male 12/12/2011 Other Health Professional Japan
Primary
Secondary
Cholecystitis Hospitalization 49 Male 1/19/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Cholecystitis Other Serious 49 Male 1/19/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Congenital Anomaly Other Serious 12/12/2011 1 Female 7 lb 1/19/2012 Physician United States
Primary
Concomitant
Hyperlipidaemia Hospitalization 4/1/1998 41 Male 2/20/2012 Physician Japan
Primary
Secondary
Concomitant
Maternal Drugs Affecting Foetus Other Serious 12/12/2011 1 Female 7 lb 3/1/2012 Other Health Professional United States
Primary
Concomitant
Pancreatitis Acute Life Threatening 4/1/1998 41 Male 3/28/2012 Physician Japan
Primary
Secondary
Concomitant
Death Neonatal Other Serious 4/8/2012 Female 4 lb 5/17/2012 Physician Australia
Primary
Concomitant
Pregnancy Other Serious 8/25/2011 8/7/2012 Physician Nigeria
Primary
Secondary
Concomitant
Pregnancy Other Serious 8/25/2011 8/14/2012 Physician Nigeria
Primary
Secondary
Concomitant
Acute Coronary Syndrome Other Serious 46 Female 8/22/2012 Other Health Professional United Kingdom
Primary
Concomitant
Maternal Drugs Affecting Foetus Congenital Anomaly 12/12/2011 1 Female 7 lb 1/19/2012 Other Health Professional Us
Primary
Concomitant
Foetal Exposure During Pregnancy Other Serious 4/8/2012 Female 4 lb 8/27/2013 Other Health Professional Country Not Specified
Primary
Concomitant
Electrolyte Imbalance Hospitalization 9/22/2012 28 Male 11/5/2012 Physician Th
Primary
Secondary
Suicide Attempt Other Serious 11/5/2012 Consumer Us
Primary
Secondary
Concomitant
Splenomegaly Other Serious 64 Male 11/8/2012 Other Health Professional Country Not Specified
Primary
Secondary
Rash Other Serious 79 Male 5/24/2013 Physician Fr
Primary
Secondary
Diabetes Mellitus Inadequate Control Hospitalization 3/2/2007 41 Male 3/8/2013 Physician Country Not Specified
Primary
Secondary
Concomitant
Splenomegaly Other Serious 64 Male 1/28/2013 Consumer Au
Primary
Secondary
Cerebrovascular Accident Hospitalization 3/25/2013 64 Male 9/9/2013 Consumer Us
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 9/30/2009 31 Female 4/12/2013 Consumer Pl
Primary
Secondary
Weight Decreased Hospitalization 11/2008 34 Female 5/1/2013 Consumer Br
Primary
Secondary
Concomitant
Virologic Failure Other Serious NotSpecified 5/2/2013 Consumer Fr
Primary
Secondary
Concomitant
Muscle Disorder Congenital Anomaly 11/28/2012 1 Female 6 lb 3/11/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious NotSpecified 7/3/2013 Other Health Professional Fr
Primary
Secondary
Oropharyngeal Candidiasis Hospitalization 6/25/2013 67 Male 7/18/2013 Physician Ug
Primary
Secondary
Treatment Noncompliance Hospitalization 1998 36 Male 9/3/2013 Physician De
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 8/26/2013 24 Female 90 lb 4/14/2014 Physician Ke
Primary
Secondary
Concomitant

Drug Data