Efavirenz combined with Nevirapine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Upper Limb Deformity Congenital Anomaly 0 Male 1/4/2006 Canada
Primary
Concomitant
Upper Limb Deformity Congenital Anomaly 1 Male 19 lb 1/2/2006 Other Health Professional Canada
Primary
Concomitant
Synovitis Other Serious 8/1/2000 40 Female 1/24/2006 Consumer United Kingdom
Primary
Secondary
Lactic Acidosis Other Serious 8 Male 2/8/2006 Other Health Professional India
Primary
Secondary
Lactic Acidosis Other Serious 10 Female 2/8/2006 Other Health Professional India
Primary
Secondary
Synovitis Other Serious 40 Female 2/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious Male 3/2/2006
Primary
Secondary
Renal Disorder Other Serious Male 3/6/2006
Primary
Secondary
Ultrasound Abdomen Abnormal Congenital Anomaly Male 7 lb 4/1/2006 Canada
Primary
Secondary
Death Death 3/23/2006 46 Male 155 lb 4/24/2006 United States
Primary
Secondary
Concomitant
Neutropenia Death 3/23/2006 46 Male 155 lb 5/2/2006 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/6/2006 53 Male 102 lb 5/17/2006 United States
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 4/6/2006 53 Male 102 lb 5/18/2006 United States
Primary
Secondary
Concomitant
Torticollis Disability 1/1/2004 Male 7 lb 6/1/2006 Canada
Primary
Concomitant
Viral Mutation Identified Death 11/1/2001 39 Male 6/20/2006
Primary
Secondary
Thrombocytopenia Other Serious 9/27/2004 Male 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/27/2004 Male 8/4/2006 Physician Japan
Primary
Secondary
Concomitant
Hallucination Other Serious 45 Male 8/3/2006 United Kingdom
Primary
Secondary
Concomitant
Hallucination Other Serious 45 Male 8/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 31 Female 8/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Productive Cough Other Serious 9/10/2001 Male 9/13/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9 Female 10/6/2006
Primary
Secondary
Concomitant
Therapeutic Product Ineffective Other Serious 6 Male 10/6/2006
Primary
Secondary
Productive Cough Other Serious 9/10/2001 Male 10/27/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Death 2/15/2001 Male 11/13/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Death 2/15/2001 Male 11/13/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Death 2/15/2001 Male 11/13/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Death 2/15/2001 Male 11/13/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Death 2/15/2001 Male 11/13/2006 Physician Japan
Primary
Secondary
Concomitant
Drug Effect Decreased Disability 9/1/2003 64 Male 11/29/2006
Primary
Secondary
Neutropenia Hospitalization 1/31/2001 Female 6 lb 12/1/2006 Other Health Professional France
Primary
Secondary
Phlebitis Hospitalization 1/1/1999 55 Male 12/6/2006 Consumer France
Primary
Secondary
Concomitant
Uterine Cyst Hospitalization Female 7 lb 12/12/2006 Consumer France
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 11/13/2006 29 Male 106 lb 12/7/2006 Other Health Professional United States
Primary
Secondary
Stevens-johnson Syndrome Death 11/13/2006 50 Male 106 lb 12/29/2006 Other Health Professional United States
Primary
Secondary
Neutropenia Other Serious 1/1/2004 Male 1/25/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/28/1999 Male 1/25/2007 Physician Japan
Primary
Secondary
Concomitant
Nodular Regenerative Hyperplasia Hospitalization 39 Male 2/7/2007 Physician France
Primary
Secondary
Glucose Tolerance Impaired Other Serious 9/22/2004 Male 2/22/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 2/22/2007 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Female 3/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Productive Cough Other Serious 9/10/2001 Male 3/16/2007 Physician Japan
Primary
Secondary
Concomitant
Glucose Tolerance Impaired Other Serious 9/22/2004 Male 4/5/2007 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 10/22/2006 Female 154 lb 10/23/2006 Pharmacist United States
Primary
Concomitant
Glucose Tolerance Impaired Other Serious 9/22/2004 Male 5/23/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
Talipes Other Serious 9/9/1999 Female 7 lb 6/8/2007 Consumer France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/14/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/28/1999 Male 6/15/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Malformation Other Serious 7/13/2007 Consumer Canada
Primary
Secondary
Urticaria Hospitalization 6/25/2007 7 Female 8/7/2007 Physician Uganda
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 11/13/2006 50 Male 101 lb 8/20/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/6/2007 24 Female 8/24/2007 Physician Kenya
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/6/2007 24 Female 9/12/2007 Physician Kenya
Primary
Secondary
Concomitant
Visceral Leishmaniasis Other Serious 3/1/2000 46 Male 10/19/2007 Other Health Professional Italy
Primary
Secondary
Visceral Leishmaniasis Other Serious 3/1/2000 46 Male 10/22/2007 Other Health Professional Italy
Primary
Secondary
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 10/29/2007 Physician Japan
Primary
Secondary
Concomitant
Visceral Leishmaniasis Other Serious 10/1/1996 46 Male 11/1/2007
Primary
Secondary
Concomitant
Liver Disorder Other Serious 36 Male 11/19/2007 Consumer United States
Primary
Secondary
Vomiting Hospitalization 25 Male 11/30/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Mitochondrial Toxicity Death 10/22/2007 35 Female 97 lb 11/30/2007 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 25 Male 12/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 25 Male 12/21/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Hypersensitivity Other Serious 10/25/2007 39 Female 12/26/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 25 Male 12/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Hospitalization 12/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Hospitalization 25 Male 1/4/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Hospitalization 25 Male 1/9/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Hospitalization 25 Male 1/9/2008 United Kingdom
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Hospitalization 25 Male 1/10/2008 United Kingdom
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Hospitalization 25 Male 1/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Vanishing Bile Duct Syndrome Hospitalization 25 Male 1/7/2008 United Kingdom
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Hospitalization 25 Male 1/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 25 Male 1/11/2008 United Kingdom
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Death 25 Male 1/11/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 25 Male 1/14/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 25 Male 1/17/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 25 Male 1/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Death 25 Male 1/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 25 Male 1/23/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Other Serious 25 Male 1/23/2008 United Kingdom
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Hospitalization 25 Male 1/18/2008 United Kingdom
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Other Serious 25 Male 1/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 25 Male 1/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Hospitalization 25 Male 1/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/14/2003 Male 1/30/2008
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Life Threatening 25 Male 1/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Life Threatening 25 Male 1/29/2008 United Kingdom
Primary
Secondary
Vomiting Other Serious 25 Male 2/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Other Serious 25 Male 2/8/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Life Threatening 25 Male 2/6/2008 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 25 Male 2/11/2008 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 25 Male 2/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abortion Induced Congenital Anomaly 33 Female 3/3/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hepatic Displacement Death 3/3/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hepatotoxicity Death 2/4/2008 40 Male 2/25/2008 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 3/13/2008 Physician Japan
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Other Serious 25 Male 3/7/2008 United Kingdom
Primary
Concomitant
Vomiting Life Threatening 3/4/2008 7 Male 3/21/2008 Physician Uganda
Primary
Secondary
Concomitant
Vanishing Bile Duct Syndrome Hospitalization 1/1/2007 25 Male 3/19/2008 United Kingdom
Primary
Secondary
Concomitant
Sex Hormone Binding Globulin Decreased Other Serious 49 Male 3/31/2008
Primary
Secondary
Concomitant
Vomiting Life Threatening 3/4/2008 7 Male 4/2/2008 Physician Uganda
Primary
Secondary
Concomitant
Pregnancy Other Serious 33 Female 4/3/2008 Other Health Professional United States
Primary
Secondary
Vulvovaginal Human Papilloma Virus Infection Other Serious 1/29/2008 17 Female 4/11/2008 Physician United States
Primary
Secondary
Concomitant
Pneumothorax Congenital Anomaly 4/11/2008 United States
Primary
Secondary
Lipodystrophy Acquired Other Serious 41 Female 4/16/2008 Physician Spain
Primary
Concomitant
Angiolipoma Other Serious 35 Female 4/16/2008
Primary
Secondary
Partial Lipodystrophy Other Serious 1/1/2001 41 Female 4/16/2008
Primary
Secondary
Lipodystrophy Acquired Other Serious 35 Female 4/17/2008 Physician Spain
Primary
Concomitant
Pregnancy Congenital Anomaly 33 Female 4/18/2008 Consumer United States
Primary
Secondary
Pneumothorax Congenital Anomaly 4/22/2008 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 4/25/2008 Physician Japan
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious Unknown 4/22/2008 Consumer United States
Primary
Secondary
Suicidal Ideation Other Serious 3/11/2008 24 Male 116 lb 5/6/2008 Peru
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 3/11/2008 24 Male 116 lb 5/9/2008 Peru
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 3/11/2008 Male 116 lb 5/19/2008 Peru
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 3/11/2008 Male 116 lb 5/21/2008 Peru
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 3/11/2008 Male 116 lb 5/28/2008 Peru
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious 25 Female 6/4/2008 United States
Primary
Concomitant
Suicidal Ideation Other Serious 3/11/2008 Male 116 lb 6/23/2008 Peru
Primary
Secondary
Concomitant
Pregnancy Congenital Anomaly 33 Female 6/24/2008 Consumer United States
Primary
Secondary
Weight Decreased Other Serious 12/28/1999 Male 6/27/2008 Physician Japan
Primary
Secondary
Concomitant
Pregnancy Other Serious 1/1/2007 26 Female 7/9/2008 Physician United States
Primary
Secondary
Concomitant
Stillbirth Other Serious 34 Female 7/9/2008 United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 3/15/2008 39 Female 8/1/2008 Uganda
Primary
Concomitant
Abortion Spontaneous Other Serious 3/15/2008 39 Female 8/6/2008 Uganda
Primary
Concomitant
Drug Level Decreased Other Serious 8/13/2008 South Africa
Primary
Secondary
Vomiting Hospitalization 4/14/2003 25 Male 8/14/2008 United Kingdom
Primary
Secondary
Concomitant
Pneumothorax Congenital Anomaly 8/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Pneumothorax Other Serious 12/1/2007 9/5/2008 United States
Primary
Secondary
Rash Other Serious 39 Male 9/11/2008 Other Health Professional United States
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 22 Male 9/12/2008 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 9/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 46 Male 9/17/2008 Other Health Professional United States
Primary
Secondary
Therapeutic Response Decreased Other Serious 47 Male 9/17/2008 Other Health Professional United States
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 22 Male 9/17/2008 United States
Primary
Secondary
Concomitant
Hepatic Displacement Congenital Anomaly 9/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Prothrombin Time Prolonged Required Intervention 38 Female 9/22/2008 France
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious 3/15/2008 39 Female 10/10/2008 Uganda
Primary
Concomitant
Weight Increased Other Serious Male 195 lb 10/17/2008 United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Other Serious Male 10/29/2008
Primary
Secondary
Rash Other Serious 10/30/2008 Other Health Professional India
Primary
Secondary
Pulmonary Tuberculosis Other Serious Female 10/30/2008
Primary
Secondary
Hepatotoxicity Other Serious 11/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Stevens-johnson Syndrome Other Serious 11/4/2008 Other Health Professional India
Primary
Secondary
Pneumothorax Other Serious 12/1/2007 11/5/2008 United States
Primary
Secondary
Drug Resistance Other Serious 11/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 11/6/2008 Other Health Professional India
Primary
Secondary

Drug Data