Efavirenz combined with Lamivudine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 7 Male 1/3/2006 Consumer South Africa
Primary
Secondary
Renal Tubular Necrosis Hospitalization 61 Male 1/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Abortion Induced Other Serious 5/1/2001 28 Female 1/5/2006 Japan
Primary
Concomitant
Septic Shock Hospitalization 10/1/2005 48 Male 165 lb 1/6/2006 Other Health Professional Portugal
Primary
Concomitant
Viral Mutation Identified Other Serious Male 12/28/2005 United States
Primary
Secondary
Tearfulness Other Serious 11/11/2005 38 147 lb 1/10/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Tearfulness Other Serious 11/11/2005 38 148 lb 1/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tearfulness Other Serious 11/11/2005 38 Male 148 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/15/2004 Male 1/12/2006 United Kingdom
Primary
Secondary
Concomitant
Tearfulness Other Serious 11/11/2005 38 Male 147 lb 1/16/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Hospitalization 23 Female 1/17/2006 Switzerland
Primary
Secondary
Concomitant
Synovitis Disability 6/1/2003 39 Male 1/18/2006 Consumer United States
Primary
Secondary
Hepatic Function Abnormal Hospitalization 5/31/1999 52 Male 1/18/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/15/2004 Male 1/19/2006 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/15/2004 Male 1/19/2006 Japan
Primary
Secondary
Concomitant
Tearfulness Other Serious 11/11/2005 38 Male 1/20/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Synovitis Disability 6/1/2003 39 Male 1/20/2006 Consumer United States
Primary
Secondary
Herpes Zoster Hospitalization 4/21/2004 Male 1/20/2006 Japan
Primary
Concomitant
Immune Reconstitution Syndrome Other Serious 1/1/2002 2 Female 1/20/2006 Other Health Professional United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 52 Male 1/20/2006 United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 10/15/2004 47 Male 1/20/2006 Japan
Primary
Concomitant
Shock Other Serious 11/9/2005 58 Female 1/20/2006 France
Primary
Secondary
Synovitis Other Serious 8/1/2000 40 Female 1/24/2006 Consumer United Kingdom
Primary
Secondary
Hepatic Failure Death 47 Female 1/25/2006 Other Health Professional France
Primary
Secondary
Polyarthritis Other Serious 6/1/2003 39 Male 1/26/2006 United States
Primary
Concomitant
Liver Disorder Hospitalization 4/13/2004 Male 1/27/2006 Japan
Primary
Secondary
Concomitant
Shock Other Serious 11/9/2005 58 Female 1/27/2006 France
Primary
Secondary
Vomiting Hospitalization 2/8/2001 Male 1/27/2006 Japan
Primary
Secondary
Concomitant
Viral Infection Hospitalization 12/22/2005 36 Female 114 lb 12/29/2005 United States
Primary
Secondary
Sensory Disturbance Other Serious 34 Male 1/30/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Isosporiasis Life Threatening 10/11/2004 Male 115 lb 2/3/2006 Brazil
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 5/13/2002 56 Male 1/31/2006 Physician Japan
Primary
Secondary
Concomitant
Premature Menopause Other Serious 2/1/1998 36 Female 2/6/2006 Consumer France
Primary
Secondary
Isosporiasis Life Threatening 10/11/2004 Male 115 lb 2/7/2006 Brazil
Primary
Secondary
Concomitant
Lactic Acidosis Other Serious 8 Male 2/8/2006 Other Health Professional India
Primary
Secondary
Lactic Acidosis Other Serious 10 Female 2/8/2006 Other Health Professional India
Primary
Secondary
Sleep Disorder Other Serious 42 Male 104 lb 2/10/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/25/2005 51 Male 2/10/2006 Other Health Professional South Africa
Primary
Secondary
Vomiting Other Serious 11/1/2003 29 Female 90 lb 2/10/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Synovitis Other Serious 40 Female 2/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Synovitis Other Serious 40 Female 2/13/2006 Physician
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/1/2004 Male 2/10/2006 Japan
Primary
Secondary
Concomitant
Isosporiasis Life Threatening 10/11/2004 Male 2/10/2006 Brazil
Primary
Concomitant
Renal Failure Hospitalization 10/25/2005 51 Male 2/13/2006 Other Health Professional South Africa
Primary
Secondary
Portal Vein Thrombosis Hospitalization 9/1/2000 35 Male 2/17/2006 Other Health Professional France
Primary
Secondary
Mycobacterium Avium Complex Infection Hospitalization 9/24/2004 54 Male 2/22/2006 Consumer United States
Primary
Secondary
Concomitant
Portal Vein Thrombosis Hospitalization 9/1/2000 35 Male 2/22/2006 Other Health Professional France
Primary
Secondary
Oedema Peripheral Hospitalization 10/17/2003 53 Male 2/24/2006 Physician United States
Primary
Concomitant
Splenic Infarction Hospitalization 41 Male 2/27/2006 United States
Primary
Secondary
Therapy Non-responder Hospitalization 15 Male 2/17/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Life Threatening 7/1/2005 36 Unknown 2/17/2006 United Kingdom
Primary
Concomitant
Hepatitis Hospitalization Male 3/1/2006 Physician United States
Primary
Secondary
Oesophageal Infection Hospitalization 3/18/2005 Male 3/2/2006 France
Primary
Concomitant
Therapy Non-responder Hospitalization 15 Male 2/28/2006 Physician United Kingdom
Primary
Secondary
Diabetic Ketoacidosis Hospitalization 48 Female 3/9/2006 Denmark
Primary
Secondary
Hypertriglyceridaemia Other Serious 12/30/2005 40 Male 3/13/2006 Other Health Professional South Africa
Primary
Secondary
Pancytopenia Other Serious 10/1/1999 Male 3/13/2006 Physician Japan
Primary
Secondary
Concomitant
Osteopenia Hospitalization 10/16/2005 45 Female 3/6/2006 United Kingdom
Primary
Secondary
Neutropenia Hospitalization 1/1/2004 48 Male 3/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 8/12/2005 24 Female 3/17/2006 Consumer South Africa
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/3/2002 Male 3/20/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/1/2005 51 Female 108 lb 3/20/2006 Other Health Professional France
Primary
Secondary
Viral Load Increased Hospitalization 1/30/2002 44 Male 110 lb 3/22/2006 Physician Germany
Primary
Secondary
Concomitant
Pregnancy Other Serious 11/10/2005 Female 3/23/2006 Physician Austria
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 34 Female 3/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 12/28/2005 35 Male 3/27/2006 Other Health Professional South Africa
Primary
Secondary
Vomiting Hospitalization 3/10/2000 Female 3/31/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 34 Female 3/24/2006 Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/1/2004 Male 4/6/2006 Physician Japan
Primary
Secondary
Concomitant
Gynaecomastia Other Serious 42 Male 4/12/2006 Consumer Brazil
Primary
Secondary
Pneumonia Hospitalization 7/3/2002 Male 4/13/2006 Physician Japan
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Other Serious 37 Male 4/6/2006
Primary
Secondary
Progressive Multifocal Leukoencephalopathy Hospitalization 32 Male 4/10/2006 Brazil
Primary
Secondary
Tumour Haemorrhage Death 1/19/2006 30 Female 4/12/2006 Other Health Professional United States
Primary
Secondary
Metabolic Acidosis Other Serious 3/27/2006 29 Female 99 lb 4/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 3/27/2006 29 Female 98 lb 4/26/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 3/23/2006 30 Female 106 lb 4/27/2006 Physician Uganda
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 10/1/2005 Female 4/27/2006 Physician Austria
Primary
Secondary
Concomitant
Viral Mutation Identified Other Serious Male 4/19/2006 United States
Primary
Secondary
Social Avoidant Behaviour Other Serious 11 Male 64 lb 4/28/2006 Consumer Spain
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 3/23/2006 30 Female 106 lb 5/1/2006 Physician Uganda
Primary
Secondary
Concomitant
Tumour Haemorrhage Hospitalization 1/27/2006 43 Male 141 lb 5/4/2006 Physician Belgium
Primary
Concomitant
Pneumonia Other Serious 3/22/2006 Female 84 lb 5/5/2006 Brazil
Primary
Secondary
Concomitant
Oral Candidiasis Other Serious 1/1/2001 Male 198 lb 5/8/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Urinary Tract Obstruction Required Intervention 4/1/2006 Male 5/8/2006 Consumer United States
Primary
Concomitant
Uveitis Other Serious 1/27/2005 Female 5/17/2006 Japan
Primary
Secondary
Concomitant
Hypospadias Congenital Anomaly 5/19/2006 Other Health Professional United States
Primary
Secondary
Haemolytic Anaemia Other Serious 9/2/2005 36 Female 5/22/2006 Other Health Professional South Africa
Primary
Secondary
Lipodystrophy Acquired Hospitalization 3/1/2003 48 Female 5/24/2006 Denmark
Primary
Secondary
Concomitant
Urinary Tract Obstruction Required Intervention 4/1/2006 Male 5/23/2006 Consumer United States
Primary
Concomitant
Hepatitis Hospitalization Male 6/1/2006 Other Health Professional Australia
Primary
Secondary
Liver Disorder Hospitalization 4/13/2004 Male 6/1/2006 Japan
Primary
Secondary
Concomitant
Vomiting Disability 10/28/2005 Male 183 lb 6/2/2006 Physician United Kingdom
Primary
Concomitant
Pregnancy Other Serious 1/1/2005 Female 6/2/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatitis C Other Serious Male 6/2/2006 Physician Japan
Primary
Secondary
Concomitant
Nasopharyngeal Cancer Death 8/1/2005 73 Male 6/13/2006 Physician Japan
Primary
Concomitant
Tuberculosis Other Serious 41 Female 6/15/2006 Consumer Brazil
Primary
Secondary
Concomitant
Viral Mutation Identified Death 11/1/2001 39 Male 6/20/2006
Primary
Secondary
Renal Impairment Other Serious 4/22/2003 Male 136 lb 6/22/2006 Spain
Primary
Concomitant
Pyrexia Other Serious 52 Male 6/23/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 3/1/2003 Male 6/23/2006 France
Primary
Secondary
Concomitant
Malaise Other Serious 6/4/1999 Male 6/23/2006 Physician United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 4/13/2004 Male 6/30/2006 Japan
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 5/4/2006 36 Male 7/3/2006 Consumer South Africa
Primary
Secondary
Concomitant
Pancytopenia Other Serious 5/26/1999 41 Male 7/5/2006 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization Female 7/6/2006 Pharmacist Brazil
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/7/2006 Physician Japan
Primary
Secondary
Concomitant
Hyperlipidaemia Other Serious 9/27/2001 Male 7/7/2006 Physician Japan
Primary
Secondary
Concomitant
Rectal Cancer Other Serious 10/15/2004 47 Male 7/7/2006 Physician Japan
Primary
Concomitant
Pancreatitis Haemorrhagic Hospitalization 5/2/2000 17 Male 7/10/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 34 Female 7/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 4/25/2006 46 Male 137 lb 7/10/2006 Physician Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 45 Male 7/3/2006 Other Health Professional Switzerland
Primary
Concomitant
Hepatitis Death Male 7/17/2006 Physician Brazil
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 56 Male 7/12/2006 Physician Italy
Primary
Concomitant
Spinal Compression Fracture Hospitalization 10/16/2005 Female 7/19/2006 United Kingdom
Primary
Secondary
Weight Decreased Hospitalization 3/10/2000 34 Female 7/10/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/19/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/10/2000 Female 7/19/2006 Physician Japan
Primary
Secondary
Concomitant
Oral Discomfort Other Serious 1/1/2005 42 Female 7/20/2006 Other Health Professional Spain
Primary
Secondary
Nasopharyngeal Cancer Death 8/1/2005 73 Male 7/21/2006 Physician Japan
Primary
Concomitant
Hyperlipidaemia Hospitalization 2/2/2001 43 Male 7/25/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/27/2004 Male 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Tearfulness Life Threatening 7/10/2006 41 Male 153 lb 7/24/2006 Consumer United States
Primary
Secondary
Concomitant
Oral Discomfort Other Serious 1/1/2005 42 Female 7/31/2006 Other Health Professional Spain
Primary
Secondary
Thrombocytopenia Other Serious 9/27/2004 Male 8/4/2006 Physician Japan
Primary
Secondary
Concomitant
Tuberculosis Other Serious 1/1/2005 43 Female 99 lb 8/7/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 2/10/2006 44 Male 8/7/2006 Physician Japan
Primary
Secondary
Concomitant
Hallucination Other Serious 45 Male 8/3/2006 United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 47 Male 8/10/2006 Consumer United States
Primary
Concomitant
Hypertriglyceridaemia Other Serious 8/6/2004 46 Male 8/10/2006 Physician Japan
Primary
Secondary
Hallucination Other Serious 45 Male 8/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 47 Male 8/14/2006 Consumer United States
Primary
Concomitant
Hepatitis Fulminant Other Serious 8/22/2005 33 Male 8/17/2006 Consumer United States
Primary
Secondary
Malaise Other Serious 2/10/2006 44 Male 8/18/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 31 Female 8/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rib Fracture Other Serious 1/6/2004 Female 8/21/2006 Physician Germany
Primary
Concomitant
Viral Load Increased Other Serious 4/1/2002 Male 123 lb 8/21/2006 Other Health Professional France
Primary
Secondary
Concomitant
Urine Calcium Decreased Hospitalization 10/16/2005 Female 143 lb 8/22/2006 United Kingdom
Primary
Secondary
Hepatic Function Abnormal Other Serious Male 8/23/2006 Physician Japan
Primary
Secondary
Concomitant
Mitochondrial Toxicity Other Serious 6/1/1998 36 Female 8/18/2006 Physician France
Primary
Concomitant
Hypospadias Congenital Anomaly Male 8/22/2006 Other Health Professional United States
Primary
Secondary
Pyrexia Other Serious 52 Male 8/28/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Other Serious 52 Male 8/30/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 7/1/2006 40 Male 9/1/2006 Physician Brazil
Primary
Concomitant
Pulmonary Embolism Hospitalization 4/28/2005 Male 9/7/2006 Physician Japan
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 49 Female 8/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/10/2006 46 Male 9/8/2006 Physician United States
Primary
Secondary
Concomitant
Von Willebrand's Disease Other Serious 38 Female 9/8/2006 Belgium
Primary
Concomitant
Sick Sinus Syndrome Other Serious 10/1/1999 Male 9/8/2006 Physician Japan
Primary
Secondary
Concomitant

Drug Data