Efavirenz combined with Fluconazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Tubular Necrosis Hospitalization 61 Male 1/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Limb Deformity Congenital Anomaly 0 Male 1/4/2006 Canada
Primary
Concomitant
Upper Limb Deformity Congenital Anomaly 1 Male 19 lb 1/2/2006 Other Health Professional Canada
Primary
Concomitant
Tearfulness Other Serious 11/11/2005 38 147 lb 1/10/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Tearfulness Other Serious 11/11/2005 38 148 lb 1/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tearfulness Other Serious 11/11/2005 38 Male 148 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/15/2004 Male 1/12/2006 United Kingdom
Primary
Secondary
Concomitant
Tearfulness Other Serious 11/11/2005 38 Male 147 lb 1/16/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 5/31/1999 52 Male 1/18/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/15/2004 Male 1/19/2006 United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/15/2004 Male 1/19/2006 Japan
Primary
Secondary
Concomitant
Tearfulness Other Serious 11/11/2005 38 Male 1/20/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 52 Male 1/20/2006 United States
Primary
Concomitant
Liver Disorder Hospitalization 4/13/2004 Male 1/27/2006 Japan
Primary
Secondary
Concomitant
Renal Tubular Disorder Other Serious Male 3/2/2006
Primary
Secondary
Renal Disorder Other Serious Male 3/6/2006
Primary
Secondary
Neutropenia Hospitalization 1/1/2004 48 Male 3/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ultrasound Abdomen Abnormal Congenital Anomaly Male 7 lb 4/1/2006 Canada
Primary
Secondary
Metabolic Acidosis Other Serious 3/27/2006 29 Female 99 lb 4/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 3/27/2006 29 Female 98 lb 4/26/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/6/2006 53 Male 102 lb 4/27/2006 United States
Primary
Secondary
Concomitant
Oral Candidiasis Other Serious 1/1/2001 Male 198 lb 5/8/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Uveitis Other Serious 1/27/2005 Female 5/17/2006 Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/6/2006 53 Male 102 lb 5/17/2006 United States
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 4/6/2006 53 Male 102 lb 5/18/2006 United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 4/13/2004 Male 6/1/2006 Japan
Primary
Secondary
Concomitant
Torticollis Disability 1/1/2004 Male 7 lb 6/1/2006 Canada
Primary
Concomitant
Liver Disorder Hospitalization 4/13/2004 Male 6/30/2006 Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 12 Female 6/28/2006 United States
Primary
Concomitant
Hyperlipidaemia Other Serious 9/27/2001 Male 7/7/2006 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 56 Male 7/12/2006 Physician Italy
Primary
Concomitant
Thrombocytopenia Other Serious 9/27/2004 Male 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/27/2004 Male 8/4/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/28/2005 Male 9/7/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/10/2006 46 Male 9/8/2006 Physician United States
Primary
Secondary
Concomitant
Productive Cough Other Serious 9/10/2001 Male 9/13/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/28/2005 Male 10/12/2006 Physician United States
Primary
Secondary
Concomitant
Productive Cough Other Serious 9/10/2001 Male 10/27/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Infarction Hospitalization 4/28/2005 Male 11/9/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Infarction Other Serious 4/28/2005 Male 11/17/2006 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 10/6/2006 40 Male 11/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Other Serious 10/6/2006 40 Male 11/22/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 11/22/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Perianal Abscess Hospitalization 12/4/2006 Male 147 lb 12/15/2006 Australia
Primary
Concomitant
Pyrexia Other Serious 6/15/2006 46 Male 12/21/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2005 Male 1/5/2007 Physician United States
Primary
Secondary
Concomitant
Perianal Abscess Hospitalization 12/4/2006 Male 147 lb 1/9/2007 Australia
Primary
Concomitant
Vasculitis Other Serious 5/21/2004 37 Female 1/11/2007 Consumer Chile
Primary
Concomitant
Abscess Drainage Hospitalization 12/4/2006 Male 147 lb 1/11/2007 Australia
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2005 Male 1/12/2007 Physician United States
Primary
Secondary
Concomitant
Pyogenic Granuloma Other Serious 53 Male 1/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 1/1/2004 Male 1/25/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Viral Load Decreased Death 12/30/2006 36 Female 209 lb 1/30/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 2/5/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 12/28/2006 50 Female 110 lb 2/8/2007 Physician United States
Primary
Secondary
Concomitant
Tearfulness Other Serious 11/11/2005 38 Male 148 lb 3/7/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tearfulness Other Serious 11/11/2005 38 148 lb 3/7/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Schistosomiasis Other Serious 31 Male 3/5/2007 United Kingdom
Primary
Secondary
Concomitant
Productive Cough Other Serious 9/10/2001 Male 3/16/2007 Physician Japan
Primary
Secondary
Concomitant
Schistosomiasis Other Serious 1/1/2004 31 Male 3/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Opportunistic Infection Death Male 4/3/2007 Physician Mexico
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 11/28/2006 48 Female 101 lb 2/16/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/14/2007 Physician Japan
Primary
Secondary
Concomitant
Opportunistic Infection Death Male 7/10/2007 Physician Mexico
Primary
Secondary
Concomitant
Multi-organ Failure Death 3/23/2007 Male 7/10/2007 Physician Mexico
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 7/11/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Urinary Tract Malformation Other Serious 7/13/2007 Consumer Canada
Primary
Secondary
Encephalitis Hospitalization 4/1/2004 43 Male 8/17/2007 United States
Primary
Secondary
Concomitant
Speech Disorder Other Serious 4/1/2004 43 Male 9/4/2007 Other Health Professional United States
Primary
Concomitant
Vitritis Hospitalization 2/1/2007 Male 163 lb 9/25/2007 Physician United Kingdom
Primary
Concomitant
Schistosomiasis Other Serious 1/1/2004 31 Male 12/11/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oral Candidiasis Hospitalization 8/3/2005 Male 12/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Death 12/6/2007 Male 78 lb 1/17/2008 United States
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Death 12/6/2007 Male 78 lb 2/15/2008 United States
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 35 Male 154 lb 2/19/2008 Other Health Professional United States
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 5/31/1999 52 Male 2/27/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 38 Male 2/25/2008 South Africa
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Death 12/6/2007 Male 78 lb 3/3/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 3/13/2008 Physician Japan
Primary
Secondary
Concomitant
Schistosomiasis Other Serious 1/1/2004 31 Male 3/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 9/28/2006 33 Male 4/10/2008 Physician Viet Nam
Primary
Secondary
Concomitant
Pyrexia Other Serious 10/27/2006 28 Female 4/11/2008 Physician Viet Nam
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 4/25/2008 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 5/22/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/7/2006 Male 5/28/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/7/2006 Male 6/3/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/1/2007 60 Male 6/10/2008 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 7/1/2007 60 Male 6/20/2008 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 3/7/2006 Male 6/20/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/1/2007 60 Male 6/24/2008 Other Health Professional United States
Primary
Secondary
Stomach Mass Hospitalization 4/14/2006 Male 7/3/2008 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/7/2006 Male 8/5/2008 United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 6/22/2008 61 Male 8/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pyrexia Death 8/7/2008 40 Male 77 lb 8/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 7/19/2008 36 Male 9/29/2008 Pharmacist Chile
Primary
Secondary
Vomiting Hospitalization 3/7/2006 Male 10/8/2008 United States
Primary
Secondary
Concomitant
Homicidal Ideation Other Serious 9/1/2008 58 Male 143 lb 10/15/2008 Other Health Professional Belgium
Primary
Concomitant
Vomiting Hospitalization 3/7/2006 Male 10/21/2008 United States
Primary
Secondary
Concomitant
Homicidal Ideation Other Serious 9/1/2008 58 Male 143 lb 10/30/2008 Other Health Professional Belgium
Primary
Concomitant
White Blood Cell Count Decreased Death 1/8/2009 53 Male 75 lb 2/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Death 1/12/2009 31 Male 148 lb 2/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 43 Male 2/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 43 Male 2/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 24 Male 3/4/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Tuberculosis Other Serious 43 Male 3/4/2009
Primary
Secondary
Concomitant
Splenomegaly Other Serious 24 163 lb 3/17/2009 Consumer Germany
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 24 Male 163 lb 4/10/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 43 Male 4/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tuberculosis Other Serious 43 Male 4/7/2009 United Kingdom
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Other Serious 24 Male 163 lb 4/15/2009
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 30 Female 4/15/2009 Other Health Professional United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 30 Female 4/22/2009 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 43 Male 4/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Lactic Acidosis Death 3/27/2009 35 Female 106 lb 4/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Torticollis Other Serious 1 Male 5/5/2009 Canada
Primary
Concomitant
Tachycardia Other Serious 30 Female 5/8/2009
Primary
Concomitant
White Blood Cell Count Increased Death 5/19/2009 32 Female 90 lb 6/1/2009 Physician United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 7/28/2008 27 Male 121 lb 11/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 33 Male 7/9/2009 United Kingdom
Primary
Secondary
Vomiting Other Serious 33 Male 7/15/2009 Germany
Primary
Secondary
Vomiting Other Serious 33 7/17/2009 Other Health Professional
Primary
Secondary
Lactic Acidosis Death 6/12/2009 31 Female 146 lb 7/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 33 Male 7/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Other Serious 33 7/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Meningitis Cryptococcal Other Serious 5/1/2007 53 Male 7/31/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 33 8/3/2009 Other Health Professional United Kingdom
Primary
Secondary
Meningitis Death 7/24/2009 42 Male 88 lb 8/24/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 11 Female 9/11/2009 Consumer South Africa
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 9/22/2009 Japan
Primary
Secondary
Concomitant
Delirium Hospitalization 11 Female 9/30/2009 Other Health Professional South Africa
Primary
Secondary
Meningitis Tuberculous Other Serious 11 Female 10/9/2009 South Africa
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 1/27/2005 Female 154 lb 10/7/2009 Japan
Primary
Secondary
Concomitant
Weight Increased Death 9/12/2009 33 Female 95 lb 10/27/2009 Physician United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2009 32 Male 11/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 11/1/2005 49 Female 11/16/2009
Primary
Secondary
Vomiting Other Serious 9/28/2006 33 Male 11/30/2009 Physician Viet Nam
Primary
Secondary
Concomitant
Vomiting Other Serious 7/8/2009 48 Female 115 lb 1/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 11/1/2005 49 Female 2/2/2010 Consumer Italy
Primary
Secondary
Concomitant
Hyponatraemia Death 6/25/2009 39 Male 93 lb 2/3/2010 United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 40 Male 3/22/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Visceral Leishmaniasis Other Serious 60 Male 6/17/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Pancytopenia Other Serious 60 Male 6/18/2010 Other Health Professional Australia
Primary
Secondary
Visceral Leishmaniasis Other Serious 60 Male 7/23/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Pancytopenia Other Serious 60 Male 8/23/2010 Consumer United States
Primary
Secondary
Arrhythmia Death 25 Male 12/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Arrhythmia Death 25 Male 1/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Arrhythmia Death 25 Male 1/10/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Arrhythmia Death 25 Male 1/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 25 Male 1/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data