Doxycycline combined with Warfarin Sodium

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Mental Status Changes Hospitalization 85 Male 3/27/2006 Physician Denmark
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 1/1/2002 61 Female 90 lb 3/29/2006 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 1/1/2002 61 Female 90 lb 4/3/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 2/26/2006 Male 258 lb 5/2/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tachycardia 1/2/2006 76 Female 160 lb 4/3/2006 Consumer United States
Primary
Secondary
Concomitant
Paraesthesia Oral 71 Female 136 lb 10/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 1/4/2007 77 2/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Respiratory Failure Hospitalization 3/9/2007 Male 3/19/2007 Pharmacist United States
Primary
Concomitant
Respiratory Failure Hospitalization 2/28/2007 47 Male 3/19/2007 Physician United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 10/14/2006 66 Female 137 lb 1/14/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening Male 7/11/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 8/3/2007 Finland
Primary
Secondary
Concomitant
Mouth Ulceration Disability 5/8/2007 89 Female 9/10/2007 Other Health Professional United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 84 Female 10/16/2007
Primary
Secondary
Concomitant
Cough 1/1/2007 84 Male 10/24/2007 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Death 10/24/2007 Male 11/14/2007 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 10/18/2007 67 Male 11/14/2007 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 10/18/2007 67 Male 2/15/2008 Physician United States
Primary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 1/1/2002 27 Female 299 lb 3/24/2008 Physician United States
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 66 Male 7/29/2008 United Kingdom
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Death 66 Male 8/6/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Toxicity Life Threatening 1/3/2006 58 Male 8/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Throat Irritation Other Serious 8/20/2007 63 Female 9/18/2008 United States
Primary
Concomitant
Suicidal Ideation Life Threatening 9/26/2008 65 Male 10/23/2008 Physician United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 9/27/2008 Male 11/14/2008 Physician United Kingdom
Primary
Concomitant
Non-small Cell Lung Cancer Stage Iv Death 12/27/2008 78 Female 140 lb 12/31/2008 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 3/24/2003 45 Female 138 lb 5/18/2009 United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/1999 40 Female 134 lb 7/16/2009 United States
Primary
Concomitant
Ventricular Fibrillation Death 5/1/2006 63 Male 7/20/2009 United States
Primary
Concomitant
Uterine Polyp Hospitalization 61 Female 8/25/2009 United States
Primary
Concomitant
Rash Pruritic 1/1/2008 75 Female 203 lb 9/3/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 5/1/2006 63 Male 210 lb 8/31/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 9/2/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
Vomiting Other Serious 8/1/2007 39 Female 9/22/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus 1/1/2004 49 Male 144 lb 9/23/2009 United States
Primary
Concomitant
Vomiting Death 86 Female 9/23/2009 United States
Primary
Concomitant
Urticaria 1/1/2008 75 Female 203 lb 10/9/2009 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 61 Female 10/17/2009 Lawyer United States
Primary
Concomitant
Spinal Fracture Other Serious 1/1/2009 Male 142 lb 11/2/2009 Physician United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Death 68 Male 10/26/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 11/4/2009 United States
Primary
Concomitant
Vomiting Other Serious 54 Female 331 lb 11/16/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 11/17/2009 Lawyer United States
Primary
Concomitant
Pain Death 68 Male 11/24/2009 United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 54 Female 331 lb 12/1/2009 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 12/11/2009 United States
Primary
Concomitant
Vomiting Other Serious 8/1/2007 39 Female 344 lb 12/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 11/19/2009 Female 12/29/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 1/13/2010 United States
Primary
Concomitant
Wound Hospitalization 71 Male 1/11/2010 United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 54 Female 331 lb 1/22/2010 Lawyer United States
Primary
Concomitant
Wound Hospitalization 71 Male 1/22/2010 Lawyer United States
Primary
Concomitant
Vomiting Life Threatening 11/19/2009 Female 2/10/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 4/2/2001 2/24/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 3/24/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 4/5/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2003 64 Male 129 lb 4/7/2010 Physician United States
Primary
Concomitant
Oxygen Saturation Decreased Hospitalization 3/12/2010 66 Male 4/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 4/15/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2003 79 Male 159 lb 4/15/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 12/1/2003 79 Male 159 lb 4/27/2010 United States
Primary
Concomitant
Menorrhagia Other Serious Female 4/23/2010 Pharmacist United States
Primary
Secondary
Concomitant
Rash Other Serious 10/1/2008 54 Male 176 lb 5/5/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 4/2/2001 5/6/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 59 Female 4/27/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious Male 5/13/2010 United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 4/2/2001 6/9/2010 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 5/19/2010 79 Male 6/14/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/2/2001 6/16/2010 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 5/19/2010 79 Male 6/24/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious Male 202 lb 7/1/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 3/16/2001 63 Male 129 lb 7/8/2010 Physician United States
Primary
Concomitant
Treatment Noncompliance Other Serious 36 Male 6/30/2010 United States
Primary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 6/5/2010 45 Female 119 lb 7/12/2010 Physician France
Primary
Secondary
Concomitant
Wound Drainage Other Serious 4/2/2001 7/13/2010 United States
Primary
Secondary
Concomitant
Febrile Bone Marrow Aplasia Hospitalization 6/5/2010 45 Female 119 lb 7/15/2010 Physician France
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/11/2006 69 Male 202 lb 7/22/2010 United States
Primary
Concomitant
Vomiting Other Serious 3/16/2001 63 Male 129 lb 7/22/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 12/1/2003 79 Male 159 lb 7/30/2010 United States
Primary
Concomitant
Sepsis Other Serious 1/1/2008 54 Male 8/17/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 3/16/2001 63 Male 129 lb 8/26/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/11/2006 69 Male 202 lb 8/28/2010 United States
Primary
Concomitant
Off Label Use Other Serious 5/25/2010 73 Female 130 lb 9/13/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious Male 9/23/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 12/1/2003 79 Male 159 lb 9/29/2010 United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 5/25/2010 73 Female 130 lb 9/30/2010 Consumer United States
Primary
Concomitant
Sepsis Other Serious 1/1/2008 54 Male 10/13/2010 Other Health Professional United States
Primary
Concomitant
Off Label Use Other Serious 5/25/2010 73 Female 130 lb 10/21/2010 Consumer United States
Primary
Concomitant
Rib Fracture 91 Male 10/13/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 11/14/2010 80 Female 119 lb 12/9/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hyperhidrosis Other Serious 11/1/2007 61 Male 179 lb 1/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Malaise Death 1/1/2008 54 Male 2/15/2011 Lawyer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/1/2002 27 Female 298 lb 2/25/2011 United States
Primary
Concomitant
Atrial Septal Defect Death 10/23/2005 49 Male 335 lb 3/18/2011 Lawyer United States
Primary
Concomitant
Hypotension Death 1/1/2008 77 Male 4/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Plantar Fasciitis Other Serious 6/27/2001 4/13/2011 Lawyer United States
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration Other Serious 6/27/2001 4/28/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Amnesia Other Serious 6/27/2001 5/4/2011 United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 6/27/2001 5/11/2011 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 6/14/2005 52 Male 205 lb 5/24/2011 Physician United States
Primary
Concomitant
Weight Bearing Difficulty Other Serious 4/25/2011 75 Female 6/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Weight Bearing Difficulty Other Serious 4/25/2011 75 Female 6/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 10/14/2003 6/2/2011 United States
Primary
Secondary
Concomitant
Atrophic Vulvovaginitis Other Serious 10/14/2003 6/21/2011 Pharmacist United States
Primary
Secondary
Concomitant
Scoliosis Disability 12/1/2003 79 Male 159 lb 6/28/2011 Lawyer United States
Primary
Secondary
Concomitant
Haemodynamic Instability Other Serious 1/1/2008 77 Male 6/29/2011 Lawyer United States
Primary
Secondary
Concomitant
Wegener's Granulomatosis Hospitalization Female 209 lb 6/30/2011 Consumer United Kingdom
Primary
Concomitant
Wegener's Granulomatosis Hospitalization Female 209 lb 7/13/2011 Other Health Professional United Kingdom
Primary
Concomitant
Acute Respiratory Distress Syndrome Life Threatening 4/16/2011 59 Female 7/13/2011 Physician United Kingdom
Primary
Concomitant
Wegener's Granulomatosis Hospitalization Female 209 lb 7/7/2011 Physician United Kingdom
Primary
Concomitant
Fatigue 1/1/2008 60 Female 181 lb 7/25/2011 Consumer United States
Primary
Secondary
Concomitant
Diverticulum Intestinal Hospitalization 10/14/2003 7/26/2011 Pharmacist United States
Primary
Secondary
Concomitant
Wegener's Granulomatosis Hospitalization Female 7/14/2011 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 1/1/2004 43 Male 273 lb 8/2/2011 United States
Primary
Concomitant
Wegener's Granulomatosis Hospitalization Female 176 lb 8/26/2011 Physician United Kingdom
Primary
Concomitant
Amnesia Hospitalization 10/14/2003 8/26/2011 Physician United States
Primary
Secondary
Concomitant
Death Death 8/24/2011 68 Male 8/29/2011 Physician United States
Primary
Concomitant
Sinusitis Hospitalization 10/14/2003 9/4/2011 Physician United States
Primary
Secondary
Concomitant
Wegener's Granulomatosis Hospitalization 22 Female 176 lb 9/13/2011 Other Health Professional United Kingdom
Primary
Concomitant
Neoplasm Malignant Death Male 9/26/2011 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization 22 Female 176 lb 9/19/2011 Physician United Kingdom
Primary
Concomitant
Condition Aggravated Hospitalization 22 Female 9/20/2011 United Kingdom
Primary
Concomitant
Lymphocyte Count Decreased Other Serious 6/1/2009 22 Female 176 lb 10/12/2011 Other Health Professional United Kingdom
Primary
Concomitant
Condition Aggravated Hospitalization Female 176 lb 10/14/2011 Physician United Kingdom
Primary
Concomitant
Sudden Cardiac Death Hospitalization 9/17/2011 75 Male 179 lb 10/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Mitral Valve Incompetence Other Serious 4/21/2008 66 Female 142 lb 11/7/2011 Lawyer United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 4/9/2010 54 Male 160 lb 11/18/2011 Lawyer United States
Primary
Concomitant
Gout Other Serious 5/11/2006 69 Male 202 lb 11/24/2011 Other Health Professional United States
Primary
Concomitant
Sudden Cardiac Death Hospitalization 9/17/2011 75 Male 179 lb 11/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 11/1/2006 67 Male 250 lb 11/18/2011 Lawyer United States
Primary
Concomitant
Cardiomegaly Hospitalization 3/14/2008 66 Male 210 lb 12/7/2011 Lawyer United States
Primary
Concomitant
Pneumonia Death 83 Male 160 lb 12/6/2011 Lawyer United States
Primary
Concomitant
Renal Injury Death 1/1/2008 77 Male 12/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Atelectasis Other Serious 71 Male 12/14/2011 Lawyer United States
Primary
Concomitant
Condition Aggravated Hospitalization 1/1/2011 68 Female 1/17/2012 Consumer United States
Primary
Secondary
Concomitant
Disease Progression Hospitalization 9/17/2011 75 Male 179 lb 2/2/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/20/2011 53 Male 180 lb 2/7/2012 Other Health Professional United Kingdom
Primary
Concomitant
Treatment Noncompliance Hospitalization 2/12/2012 69 Male 228 lb 2/16/2012 Pharmacist United States
Primary
Secondary
Treatment Noncompliance Hospitalization 2/12/2012 69 Male 228 lb 2/16/2012 Pharmacist United States
Primary
Secondary
Electrocardiogram Qt Prolonged Hospitalization 5/27/2005 58 Male 206 lb 3/13/2012 Lawyer United States
Primary
Concomitant
Wheezing Hospitalization 67 Male 180 lb 3/16/2012 Lawyer United States
Primary
Concomitant
Vaginal Ulceration Hospitalization 62 Female 187 lb 3/26/2012 Lawyer United States
Primary
Concomitant
Meniscus Lesion Other Serious 9/2/2009 54 Female 182 lb 4/26/2012 Lawyer United States
Primary
Concomitant
Laboratory Test Abnormal Death Male 183 lb 5/9/2012 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 71 Male 5/14/2012 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 3/22/2011 54 Female 11/21/2011 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 40 Male 379 lb 5/16/2012 Consumer United States
Primary
Concomitant
Palpitations Hospitalization 87 Female 130 lb 6/5/2012 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/15/2012 83 Male 170 lb 6/15/2012 Physician United States
Primary
Secondary
Concomitant