Doxorubicin Hcl combined with Trastuzumab

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Scleroderma Other Serious 7/1/2003 37 Female 1/24/2007 Other Health Professional Japan
Primary
Secondary
Scleroderma Other Serious 7/1/2003 37 Female 1/30/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 4/29/2007 Female 6/28/2007 Physician United Kingdom
Primary
Secondary
Acute Monocytic Leukaemia Other Serious 4/11/2007 44 Female 206 lb 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Acute Monocytic Leukaemia Other Serious 4/11/2007 Female 10/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 4/11/2007 44 Female 206 lb 12/31/2007 Physician United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Other Serious 4/11/2007 Female 206 lb 1/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy 29 Female 1/10/2008 United States
Primary
Secondary
Hepatocellular Injury Other Serious 31 Female 1/26/2008 Consumer United Kingdom
Primary
Concomitant
Waist Circumference Increased Other Serious 1/1/2004 29 Female 2/15/2008
Primary
Secondary
Concomitant
Liver Injury Other Serious 31 Female 3/12/2008 Other Health Professional Spain
Primary
Secondary
Liver Injury Other Serious 31 Female 3/13/2008 Other Health Professional Spain
Primary
Secondary
Hepatotoxicity Other Serious 31 Female 5/15/2008
Primary
Secondary
Pain Hospitalization 4/5/2008 44 Female 5/22/2008 Consumer United States
Primary
Secondary
Blood Triglycerides Increased Female 5/22/2008 Other Health Professional United States
Primary
Secondary
Pain Hospitalization 44 Female 5/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Hepatitis Viral Hospitalization 3/31/2008 Female 10/1/2008 Physician United States
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 10/21/2008 11/17/2008 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 9/15/2008 11/18/2008 Physician United Kingdom
Primary
Secondary
Dehydration Hospitalization 9/15/2008 11/18/2008 Physician United Kingdom
Primary
Secondary
Pyrexia Hospitalization 12/12/2008 54 Female 182 lb 12/19/2008 Physician United States
Primary
Secondary
Transfusion Reaction Hospitalization 12/12/2008 54 Female 182 lb 1/12/2009 Physician United States
Primary
Secondary
Metastases To Ovary Other Serious 56 Female 1/12/2009 Netherlands
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 44 Female 1/14/2009 Netherlands
Primary
Secondary
Concomitant
Metastases To Ovary Other Serious 56 Female 1/22/2009 Netherlands
Primary
Secondary
Concomitant
Blood Triglycerides Increased Female 1/26/2009 Other Health Professional United States
Primary
Secondary
Pyrexia Hospitalization 12/10/2008 Female 1/26/2009 Consumer United States
Primary
Secondary
Concomitant
Rash Other Serious 2/9/2009 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/10/2008 Female 2/13/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 45 Female 2/18/2009 Other Health Professional Italy
Primary
Secondary
Thrombosis Other Serious 45 Female 2/23/2009 Other Health Professional Italy
Primary
Secondary
Sinus Tachycardia Hospitalization 45 Female 3/10/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious Female 4/15/2009 Physician Greece
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious Female 4/15/2009 Physician Greece
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 10/21/2008 4/27/2009 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 31 Female 5/5/2009 Other Health Professional Canada
Primary
Secondary
Pneumothorax Hospitalization 7/7/2008 44 Female 5/5/2009 Physician United Kingdom
Primary
Secondary
Gastric Ulcer Perforation Other Serious 3/7/2009 60 Female 5/7/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Metastases To Central Nervous System Other Serious 7/1/2002 38 Female 5/8/2009 Other Health Professional Italy
Primary
Secondary
Pyrexia Other Serious 4/30/2008 55 Female 5/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Disease Progression Death 78 Male 6/3/2009 Consumer United Kingdom
Primary
Concomitant
Ejection Fraction Decreased Hospitalization 5/13/2009 Female 6/5/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Ejection Fraction Decreased Hospitalization 5/13/2009 Female 6/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 31 Female 6/22/2009 Other Health Professional Spain
Primary
Concomitant
Hepatotoxicity Other Serious 31 Female 7/1/2009 Other Health Professional Spain
Primary
Concomitant
Ejection Fraction Decreased Hospitalization 5/13/2009 Female 7/10/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Trisomy 21 Congenital Anomaly Female 8/12/2009 Physician United Kingdom
Primary
Secondary
Syncope Other Serious 1/4/2002 39 Female 179 lb 11/9/2009 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 43 Female 12/1/2009 Other Health Professional Spain
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 10/21/2008 1/11/2010 Physician United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 5/29/2008 65 Female 123 lb 2/9/2010 Other Health Professional United States
Primary
Secondary
Neuropathy Peripheral Other Serious 5/29/2008 65 Female 123 lb 2/18/2010 Other Health Professional United States
Primary
Secondary
Non-hodgkin's Lymphoma Other Serious 6/2/2008 Female 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 9/24/2003 Female 159 lb 3/19/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 48 Female 3/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Erythema Multiforme Other Serious 9/9/2009 Female 194 lb 3/24/2010 Physician United States
Primary
Secondary
Ejection Fraction Decreased Other Serious 56 Female 4/29/2010 United States
Primary
Secondary
Ejection Fraction Decreased Other Serious 35 Female 4/29/2010 United States
Primary
Secondary
Ejection Fraction Decreased Other Serious 44 Female 4/29/2010 United States
Primary
Secondary
Complication Of Pregnancy Other Serious 38 Female 6 lb 5/7/2010 Physician Ireland
Primary
Secondary
Concomitant
Syncope Hospitalization 9/13/2005 46 Female 161 lb 5/11/2010 Physician Italy
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 9/27/2005 46 Female 161 lb 5/13/2010 Physician Italy
Primary
Secondary
Phrenic Nerve Paralysis Other Serious 58 Female 5/14/2010 Physician Lebanon
Primary
Secondary
Blood Creatinine Increased Other Serious 5/19/2010 Other Health Professional United States
Primary
Secondary
Blood Creatinine Increased Other Serious 5/19/2010 Other Health Professional United States
Primary
Secondary
Left Atrial Dilatation Other Serious 1/1/2009 57 Female 6/2/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Tendon Disorder Other Serious 5/1/2005 Female 3 lb 6/3/2010 Physician Ireland
Primary
Concomitant
Left Atrial Dilatation Other Serious 1/1/2009 57 Female 6/11/2010 Other Health Professional Portugal
Primary
Secondary
Concomitant
Syncope Hospitalization 9/13/2005 46 Female 161 lb 6/12/2010 Physician Italy
Primary
Secondary
Concomitant
Complication Of Pregnancy Female 212 lb 6/24/2010 Physician Ireland
Primary
Secondary
Concomitant
Scleroderma Other Serious 7/1/2003 37 Female 6/24/2010 Japan
Primary
Secondary
Pregnancy Other Serious Female 212 lb 7/1/2010 Physician Ireland
Primary
Secondary
Concomitant
Complication Of Pregnancy Other Serious Female 212 lb 7/6/2010 Physician Ireland
Primary
Secondary
Concomitant
Vomiting Hospitalization Female 138 lb 7/9/2010 Physician United States
Primary
Secondary
Neutropenia Other Serious 6/30/2010 61 Female 138 lb 7/20/2010 Physician United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 7/30/2010 Other Health Professional United States
Primary
Secondary
Electrocardiogram Qt Prolonged Hospitalization 7/30/2010 Other Health Professional United States
Primary
Secondary
Neutropenia Hospitalization 6/30/2010 61 Female 138 lb 8/17/2010 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 5/21/2010 48 Female 8/18/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Capillary Leak Syndrome Hospitalization 8/4/2010 60 Female 128 lb 8/20/2010 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 5/21/2010 48 Female 8/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 7/19/2007 46 Female 10/5/2010 Physician United States
Primary
Secondary
Death Other Serious 3/28/2010 81 Female 163 lb 11/18/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 44 Female 3/28/2011 Physician United States
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Death 10/21/2008 3/31/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 35 Female 4/20/2011 Physician United Kingdom
Primary
Secondary
Lymphoedema Other Serious 48 Female 7/22/2011 Other Health Professional Spain
Primary
Secondary
Lymph Node Fibrosis Other Serious 48 Female 8/12/2011 Physician Spain
Primary
Secondary
Atrial Fibrillation Other Serious 11/1/2010 78 Female 124 lb 8/30/2011 Consumer United States
Primary
Concomitant
Hypoxia Death 70 Female 9/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Lactic Acidosis Hospitalization 70 Female 9/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Lactic Acidosis Hospitalization 70 Female 9/30/2011 Other Health Professional United States
Primary
Secondary
Depression Other Serious Female 10/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Septic Shock Disability 9/18/2011 62 Female 148 lb 10/31/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Metastases To Bone Death 33 Female 11/9/2011 Other Health Professional Israel
Primary
Secondary
Concomitant
Hepatic Failure Other Serious Female 11/17/2011 Physician Israel
Primary
Secondary
Concomitant
Cardiac Cirrhosis Other Serious 37 Female 11/20/2011 Other Health Professional Israel
Primary
Secondary
Wound Infection Hospitalization 4/15/2002 56 Female 11/25/2011 Other Health Professional United States
Primary
Secondary
Hyperglycaemia Hospitalization 11/5/2001 60 Female 11/29/2011 Physician United States
Primary
Secondary
Pyrexia Hospitalization 10/10/2001 11 Male 11/29/2011 Physician United States
Primary
Secondary
Infection Hospitalization 63 Female 11/30/2011 Physician United States
Primary
Secondary
Concomitant
Liver Scan Abnormal Death 33 Female 12/1/2011 Other Health Professional Israel
Primary
Secondary
Pyrexia Hospitalization 10/1/2001 11 Male 12/22/2011 Consumer United States
Primary
Secondary
Infection Life Threatening 12/8/2001 12 Male 12/23/2011 Physician United States
Primary
Secondary
Neoplasm Malignant Other Serious Female 1/4/2012 Physician United States
Primary
Secondary
Pain In Extremity Hospitalization 12/23/2011 42 Female 150 lb 1/4/2012 Physician Germany
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious Female 1/5/2012 Physician United States
Primary
Secondary
Neoplasm Malignant Other Serious Female 1/5/2012 Physician United States
Primary
Secondary
Altered State Of Consciousness Other Serious Female 1/19/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Depression Other Serious Female 1/19/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/8/2012 43 Female 121 lb 1/24/2012 Physician Germany
Primary
Secondary
Pyrexia Other Serious 1/8/2012 43 Female 121 lb 1/27/2012 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 1/8/2012 43 Female 121 lb 2/6/2012 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 1/8/2012 43 Female 121 lb 2/7/2012 Physician Germany
Primary
Secondary
Right Ventricular Dysfunction Hospitalization 1/19/2012 68 Female 2/9/2012 Physician United Kingdom
Primary
Secondary
Concomitant
Lactic Acidosis Death 70 Female 2/10/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Infection Hospitalization 10/10/2001 11 Male 2/17/2012 Physician United States
Primary
Secondary
Hyperglycaemia Hospitalization 6/27/2002 63 Female 2/23/2012 Physician United States
Primary
Secondary
Concomitant
Hypoalbuminaemia Hospitalization 4/15/2002 56 Female 2/23/2012 Physician United States
Primary
Secondary
Hyperglycaemia Life Threatening 11/5/2001 70 Female 2/23/2012 Physician United States
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 1/4/2004 21 Female 2/28/2012 Physician United States
Primary
Secondary
Weight Decreased Hospitalization 2/13/2012 72 Female 117 lb 2/28/2012 Physician Germany
Primary
Secondary
Hypokalaemia Other Serious 2/20/2004 13 2/29/2012 Physician United States
Primary
Secondary
Concomitant
Pneumonitis Death Female 3/1/2012 Physician Spain
Primary
Secondary
General Physical Health Deterioration Hospitalization 2/21/2012 50 Female 3/1/2012 Physician Germany
Primary
Secondary
Leukocytosis Hospitalization 2/24/2012 39 Female 119 lb 3/2/2012 Physician Germany
Primary
Secondary
Blood Alkaline Phosphatase Other Serious Female 3/6/2012 Physician Spain
Primary
Secondary
General Physical Health Deterioration Hospitalization 2/21/2012 50 Female 3/8/2012 Physician Germany
Primary
Secondary
Cardiovascular Disorder Hospitalization 2/24/2012 39 Female 119 lb 3/8/2012 Physician Germany
Primary
Secondary
Thrombophlebitis Hospitalization 2/28/2012 57 Female 190 lb 3/8/2012 Physician Germany
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 2/28/2012 57 Female 190 lb 3/9/2012 Physician Germany
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/2/2012 40 Female 130 lb 3/9/2012 Physician Germany
Primary
Secondary
Neuralgia Hospitalization 2/14/2012 38 Female 198 lb 3/13/2012 Physician Germany
Primary
Secondary
Multiple Myeloma Other Serious 57 3/14/2012 Physician Turkey
Primary
Secondary
Concomitant
Pleuritic Pain Hospitalization 7/22/2004 56 Female 3/26/2012 Other Health Professional United States
Primary
Secondary
Pyrexia Hospitalization 3/18/2012 50 Female 112 lb 3/27/2012 Physician Germany
Primary
Secondary
Thrombocytopenia Death 3/28/2012 Other Health Professional United States
Primary
Secondary
Myalgia Other Serious Female 3/29/2012 Physician United States
Primary
Secondary
Febrile Neutropenia Hospitalization 3/2/2012 40 Female 130 lb 4/5/2012 Physician Germany
Primary
Secondary
Abdominal Pain Hospitalization 3/29/2012 40 Female 132 lb 4/5/2012 Physician Germany
Primary
Secondary
Thrombophlebitis Hospitalization 2/28/2012 57 Female 190 lb 4/16/2012 Physician Germany
Primary
Secondary
Concomitant
Thrombophlebitis Hospitalization 2/28/2012 57 Female 190 lb 4/17/2012 Physician Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 2/13/2012 72 Female 117 lb 4/20/2012 Physician Germany
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 3/16/2012 56 Female 130 lb 4/24/2012 Physician Germany
Primary
Secondary
Pyrexia Hospitalization 4/15/2012 45 Female 146 lb 4/26/2012 Physician Germany
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious Female 4/27/2012 Physician Spain
Primary
Secondary
Pyrexia Hospitalization 4/15/2012 45 Female 146 lb 4/30/2012 Physician Germany
Primary
Secondary
Concomitant
Embolism Other Serious 4/23/2012 41 Female 139 lb 5/1/2012 Physician Germany
Primary
Secondary
Concomitant
Embolism Other Serious 4/23/2012 41 Male 139 lb 5/7/2012 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/13/2012 72 Female 117 lb 5/7/2012 Physician Germany
Primary
Secondary
Concomitant

Drug Data