Doxorubicin Hcl combined with Paclitaxel

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Polymyositis Other Serious 54 Female 156 lb 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 48 Female 3/7/2006 United States
Primary
Concomitant
Skin Ulcer Other Serious 69 Female 3/7/2006 United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 61 Female 3/7/2006 United States
Primary
Concomitant
Skin Exfoliation Other Serious 46 Female 3/7/2006 Physician United States
Primary
Concomitant
Skin Exfoliation Other Serious 47 Female 3/7/2006 Physician United States
Primary
Concomitant
Treatment Related Secondary Malignancy Other Serious Female 3/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 11/17/2005 52 Female 272 lb 5/11/2006 Physician Spain
Primary
Secondary
Concomitant
Polymyositis Other Serious 7/7/2005 54 Female 156 lb 5/16/2006 Physician United States
Primary
Secondary
Concomitant
Neoplasm Progression Life Threatening 60 Female 5/17/2006 United States
Primary
Secondary
Urinary Tract Infection Hospitalization 5/17/2006 5/31/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 5/12/2006 65 Female 6/1/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 5/17/2006 6/19/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/7/2006 65 Female 6/20/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 10/15/2005 49 Female 190 lb 6/14/2006 Physician United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 47 Female 6/12/2006 United States
Primary
Secondary
Pyrexia Hospitalization 6/7/2006 65 Female 7/17/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 6/27/2006 56 Female 196 lb 7/14/2006 Physician Italy
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 6/27/2006 56 Female 196 lb 8/11/2006 Physician Italy
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 67 Female 8/21/2006 Other Health Professional United States
Primary
Secondary
Leukocytosis Hospitalization 67 Female 8/18/2006 Other Health Professional United States
Primary
Secondary
Pyrexia Hospitalization 6/7/2006 65 Female 8/28/2006 Other Health Professional Belgium
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 67 Female 8/24/2006 United States
Primary
Secondary
White Blood Cell Count Increased Hospitalization 67 Female 8/24/2006 United States
Primary
Secondary
Wound Complication Required Intervention 7/17/2006 49 Unknown 9/18/2006 Physician United States
Primary
Secondary
Neutropenia Hospitalization 10/6/2006 Female 126 lb 10/10/2006 United States
Primary
Secondary
Malignant Neoplasm Progression Other Serious 4/1/2003 44 Female 10/23/2006 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Hospitalization 10/2/2006 50 Female 143 lb 10/16/2006 Physician Italy
Primary
Secondary
Tooth Extraction Other Serious 10/16/2001 51 Female 10/28/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 67 Female 10/20/2006 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 10/2/2006 50 Female 143 lb 10/26/2006 Physician Italy
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 5/28/2006 37 Female 130 lb 10/26/2006 Physician Italy
Primary
Secondary
Concomitant
Leukocytosis Hospitalization 67 Female 10/26/2006 Other Health Professional United States
Primary
Concomitant
Arthropathy Other Serious 57 Female 11/1/2006 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Joint Stiffness Other Serious 50 Female 11/1/2006 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Viral Infection Hospitalization 9/21/2006 38 Female 11/16/2006 Physician United States
Primary
Secondary
Concomitant
Arthropathy Other Serious 1/9/2004 57 Female 11/23/2006 Korea, Republic Of
Primary
Secondary
Febrile Neutropenia Hospitalization 11/18/2006 67 Female 149 lb 12/1/2006 Physician Spain
Primary
Secondary
Supraventricular Tachycardia Hospitalization 11/26/2006 60 Female 12/13/2006 Physician United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 11/26/2006 60 Female 12/19/2006 Physician United States
Primary
Secondary
Concomitant
Scleroderma Other Serious 7/1/2003 37 Female 1/24/2007 Other Health Professional Japan
Primary
Secondary
Scleroderma Other Serious 7/1/2003 37 Female 1/30/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/21/2006 52 Female 1/26/2007 Physician India
Primary
Secondary
Vomiting Other Serious 52 Female 2/26/2007 Other Health Professional Poland
Primary
Secondary
Gastrointestinal Haemorrhage Life Threatening 3/1/2007 68 Female 128 lb 3/9/2007 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/2/2007 50 Female 4/11/2007 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 45 Female 5/22/2007 Physician Australia
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 49 Female 5/22/2007 Physician Australia
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 4/29/2007 Female 6/28/2007 Physician United Kingdom
Primary
Secondary
Leukaemia Other Serious 7/11/2007 64 Female 8/1/2007 Physician Japan
Primary
Concomitant
Vision Blurred Hospitalization 9/10/2007 42 Female 9/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 10/3/2007 Female 149 lb 11/2/2007 Physician United Kingdom
Primary
Concomitant
Hypertension Other Serious 9/20/2007 42 Female 168 lb 11/12/2007 Physician United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 11/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Vocal Cord Paralysis Other Serious 48 Female 12/6/2007 Other Health Professional United States
Primary
Secondary
Vocal Cord Paralysis 48 Female 12/13/2007 United States
Primary
Secondary
Drug Exposure During Pregnancy 29 Female 1/10/2008 United States
Primary
Secondary
Hepatic Failure Other Serious 10/3/2007 Female 149 lb 1/15/2008 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 10/15/2004 50 Female 157 lb 1/28/2008 Other Health Professional Belgium
Primary
Secondary
Hepatic Failure Other Serious 10/3/2007 Female 149 lb 1/30/2008 Physician United Kingdom
Primary
Concomitant
Somnolence Other Serious 64 Male 1/31/2008 Other Health Professional Spain
Primary
Secondary
Somnolence Other Serious 64 Male 1/31/2008 Other Health Professional Italy
Primary
Secondary
Somnolence Hospitalization 64 Male 2/9/2008 Spain
Primary
Secondary
Hypertension Other Serious 9/20/2007 42 Female 168 lb 2/15/2008 Physician United States
Primary
Secondary
Concomitant
Waist Circumference Increased Other Serious 1/1/2004 29 Female 2/15/2008
Primary
Secondary
Concomitant
Pancreatitis Chronic Other Serious 5/5/2008 Other Health Professional Russian Federation
Primary
Secondary
Pancreatitis Chronic Other Serious 5/8/2008 Other Health Professional Russian Federation
Primary
Secondary
Mucosal Inflammation Hospitalization 3/22/2008 5/14/2008 Other Health Professional United States
Primary
Secondary
Blood Triglycerides Increased Female 5/22/2008 Other Health Professional United States
Primary
Secondary
Pregnancy Other Serious 38 Female 5/23/2008 Other Health Professional United States
Primary
Secondary
Hepatic Failure Death 9/21/2007 Female 149 lb 6/13/2008 Physician United Kingdom
Primary
Concomitant
Tachypnoea Other Serious 48 Female 6/25/2008 Spain
Primary
Secondary
Left Ventricular Dysfunction Other Serious 5/17/2008 53 Female 130 lb 6/26/2008 Physician United States
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Hospitalization 5/17/2008 53 Female 130 lb 7/24/2008 Physician United States
Primary
Secondary
Concomitant
Spleen Disorder Other Serious 36 Female 8/29/2008 United States
Primary
Secondary
Concomitant
Myalgia Other Serious Female 9/18/2008 Physician Greece
Primary
Secondary
Concomitant
Hypersensitivity Other Serious Female 9/18/2008 Physician Greece
Primary
Secondary
Concomitant
Pyrexia Hospitalization 6/1/2007 9/30/2008 Physician Singapore
Primary
Secondary
Hepatitis Viral Hospitalization 3/31/2008 Female 10/1/2008 Physician United States
Primary
Secondary
Ejection Fraction Decreased Other Serious 10/4/2006 10/16/2008 Physician United Kingdom
Primary
Secondary
Urine Flow Decreased Other Serious 43 Female 10/23/2008 Other Health Professional United States
Primary
Secondary
Urine Flow Decreased Other Serious 43 Female 10/29/2008 Other Health Professional United States
Primary
Secondary
Acute Respiratory Distress Syndrome Other Serious 10/4/2008 51 Female 10/29/2008 Physician United States
Primary
Secondary
Pyrexia Hospitalization 6/1/2007 134 lb 10/29/2008 Physician Singapore
Primary
Secondary
Left Ventricular Dysfunction 7/5/2007 Female 137 lb 11/4/2008 Physician Norway
Primary
Secondary
Concomitant
Acute Respiratory Distress Syndrome Other Serious 10/4/2008 51 Female 11/13/2008 Physician United States
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Life Threatening 10/21/2008 11/17/2008 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 9/15/2008 11/18/2008 Physician United Kingdom
Primary
Secondary
Dehydration Hospitalization 9/15/2008 11/18/2008 Physician United Kingdom
Primary
Secondary
Duodenal Ulcer Hospitalization 10/4/2008 Female 11/19/2008 Physician United Kingdom
Primary
Secondary
Herpes Zoster Hospitalization 9/18/2008 Female 11/19/2008 Other Health Professional United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 64 Female 168 lb 11/25/2008 Physician United States
Primary
Secondary
Peritonitis Hospitalization 50 Female 12/4/2008 Physician Germany
Primary
Concomitant
Skin Necrosis Hospitalization 5/20/2008 Female 12/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Chest Pain Hospitalization 10/14/2008 Female 12/11/2008 Physician United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 6/24/2008 12/11/2008 Physician United States
Primary
Secondary
Ejection Fraction Decreased Other Serious 58 Female 12/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/11/2008 Female 12/11/2008 Physician United States
Primary
Secondary
Blood Amylase Increased Other Serious 1/19/2007 12/11/2008 Physician United States
Primary
Secondary
Vision Blurred Other Serious 2/7/2008 Male 12/12/2008 Physician United States
Primary
Secondary
Myalgia Other Serious 1/2/2007 12/12/2008 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 11/16/2006 Female 12/15/2008 Physician United States
Primary
Concomitant
Nail Disorder Other Serious 1/3/2007 12/15/2008 Physician United States
Primary
Concomitant
Hyperbilirubinaemia Other Serious 2/8/2007 12/16/2008 Physician United States
Primary
Concomitant
Insomnia Other Serious 7/9/2007 12/16/2008 Physician United States
Primary
Concomitant
Alanine Aminotransferase Increased Other Serious 10/27/2006 12/16/2008 Physician United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 9/6/2006 12/16/2008 Physician United States
Primary
Concomitant
Tinnitus Other Serious 10/15/2006 12/16/2008 Physician United States
Primary
Concomitant
Hypocalcaemia Other Serious 7/16/2007 12/17/2008 Physician United States
Primary
Concomitant
Death Other Serious Female 12/18/2008 Physician United Kingdom
Primary
Secondary
Menstruation Irregular Other Serious 12/1/2006 12/18/2008 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 4/9/2008 12/18/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/12/2008 54 Female 182 lb 12/19/2008 Physician United States
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 6/24/2008 12/19/2008 Physician United States
Primary
Secondary
Blood Bilirubin Increased Other Serious 12/19/2008 Physician United Kingdom
Primary
Secondary
Aspartate Aminotransferase Increased Other Serious 9/6/2006 12/24/2008 Physician United States
Primary
Concomitant
Peripheral Sensory Neuropathy Other Serious 11/8/2008 1/8/2009 Physician United States
Primary
Secondary
Transfusion Reaction Hospitalization 12/12/2008 54 Female 182 lb 1/12/2009 Physician United States
Primary
Secondary
Peripheral Sensory Neuropathy Other Serious 11/8/2008 1/15/2009 Physician United States
Primary
Secondary
Tooth Extraction Other Serious 60 Female 1/16/2009 Other Health Professional Netherlands
Primary
Concomitant
Peripheral Sensory Neuropathy Other Serious 11/8/2008 1/22/2009 Physician United States
Primary
Secondary
Blood Triglycerides Increased Female 1/26/2009 Other Health Professional United States
Primary
Secondary
Pyrexia Hospitalization 12/10/2008 Female 1/26/2009 Consumer United States
Primary
Secondary
Concomitant
Rash Other Serious 2/9/2009 Consumer United States
Primary
Secondary
Concomitant
Hypertension Other Serious 9/20/2007 42 Female 168 lb 2/12/2009 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/10/2008 Female 2/13/2009 Consumer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 45 Female 2/18/2009 Other Health Professional Italy
Primary
Secondary
Restrictive Cardiomyopathy Other Serious 7/17/2008 Female 121 lb 2/19/2009 Physician Japan
Primary
Secondary
Concomitant
Myocarditis Other Serious Unknown 2/9/2009 United States
Primary
Secondary
Concomitant
Paronychia Other Serious Unknown 2/9/2009 United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious Unknown 2/9/2009 United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious Unknown 2/9/2009 United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious Unknown 2/9/2009 United States
Primary
Secondary
Concomitant
Rash Other Serious Unknown 2/9/2009 United States
Primary
Secondary
Concomitant
Restrictive Cardiomyopathy Other Serious 7/17/2008 Female 121 lb 2/23/2009 Physician Japan
Primary
Secondary
Concomitant
Thrombosis Other Serious 45 Female 2/23/2009 Other Health Professional Italy
Primary
Secondary
Pulmonary Embolism Death 2/7/2009 51 Female 205 lb 2/27/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Death 2/7/2009 51 Female 205 lb 3/4/2009 Physician United States
Primary
Secondary
Concomitant
Restrictive Cardiomyopathy Other Serious 7/17/2008 Female 121 lb 3/5/2009 Physician Japan
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 45 Female 3/10/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Hepatic Failure Hospitalization 12/29/2008 59 Female 3/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Other Serious 11/11/2008 61 Female 149 lb 3/18/2009 Physician United States
Primary
Secondary
Concomitant
Bartholin's Abscess Hospitalization 3/9/2009 54 Female 3/25/2009 Other Health Professional United States
Primary
Secondary
Hepatic Failure Hospitalization 12/29/2008 59 Female 3/27/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Bartholin's Abscess Hospitalization 3/9/2009 54 Female 249 lb 4/3/2009 Other Health Professional United States
Primary
Secondary
Gastrointestinal Disorder Hospitalization 2/17/2009 Female 4/8/2009 Physician United States
Primary
Secondary
Oedema Peripheral Other Serious 3/23/2009 47 Female 4/9/2009 Physician India
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 3/27/2009 57 Female 4/10/2009 Physician Peru
Primary
Secondary
Respiratory Tract Infection Hospitalization 3/27/2009 57 Female 4/14/2009 Physician Peru
Primary
Secondary
Respiratory Tract Infection Hospitalization 3/27/2009 57 Female 4/17/2009 Physician United States
Primary
Secondary

Drug Data