Doxorubicin Hcl combined with Leucovorin Calcium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Stomatitis Other Serious 11/21/2005 Female 138 lb 1/17/2006 United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 12/6/2005 Female 152 lb 1/19/2006 United States
Primary
Secondary
Rectal Haemorrhage Life Threatening 10/10/2005 70 Male 181 lb 2/17/2006 Physician France
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 8/19/2005 74 Male 126 lb 9/13/2006 Physician Japan
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 5/1/1999 55 Female 12/12/2006
Primary
Secondary
Lip And/or Oral Cavity Cancer Other Serious 5/1/1999 54 Female 12/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Lip And/or Oral Cavity Cancer Other Serious 5/1/1999 54 Female 12/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Lip And/or Oral Cavity Cancer Other Serious 5/1/1999 Female 1/10/2007 United States
Primary
Secondary
Vith Nerve Paralysis Other Serious 10/22/2006 23 Male 172 lb 1/10/2007 Physician Finland
Primary
Secondary
Concomitant
Weight Increased Other Serious 67 Male 3/23/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/30/2005 48 Male 4/2/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 2/22/2007 14 Male 62 lb 4/12/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Weight Increased Other Serious 67 Male 6/11/2007 Consumer United States
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 4/1/2005 13 Male 7/2/2007 Other Health Professional United States
Primary
Secondary
Squamous Cell Carcinoma Other Serious 5/1/1999 56 Female 7/9/2007 Physician United States
Primary
Secondary
Concomitant
Vith Nerve Paralysis Other Serious 10/22/2006 23 Male 172 lb 7/9/2007 United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 21 Female 9/5/2007 Other Health Professional United States
Primary
Secondary
Sepsis Neonatal Hospitalization Male 8/16/2007 Physician United States
Primary
Secondary
Vomiting Other Serious 14 Female 10/2/2007 Other Health Professional United States
Primary
Secondary
Interacting
Vomiting Other Serious 8 Male 10/2/2007
Primary
Secondary
Concomitant
Vomiting Other Serious 14 Female 10/2/2007
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 2/22/2007 14 Male 62 lb 11/29/2007 Physician Germany
Primary
Secondary
Concomitant
Refusal Of Treatment By Relative Other Serious 6 Male 1/22/2008 Physician Turkey
Primary
Concomitant
Haemoglobin Decreased Death 6 Male 3/10/2008
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 2/3/2008 Female 176 lb 4/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 3/20/2008 48 Male 302 lb 4/15/2008 Consumer Canada
Primary
Concomitant
Hypersensitivity Other Serious 3/20/2008 48 Male 302 lb 4/22/2008 Consumer Canada
Primary
Concomitant
Neutropenic Sepsis Other Serious 4/16/2008 52 Male 157 lb 5/21/2008 Physician Malaysia
Primary
Concomitant
Respiratory Disorder Other Serious 3/20/2008 48 Male 302 lb 5/29/2008 Consumer Canada
Primary
Concomitant
Refusal Of Treatment By Relative Disability 6 Male 5/19/2008 Physician Turkey
Primary
Concomitant
Muscle Disorder Disability 5/13/2006 Male 6/23/2008 Consumer Germany
Primary
Secondary
Concomitant
Odynophagia Hospitalization 9/30/2006 Male 61 lb 7/10/2008 United States
Primary
Secondary
Neutropenia Hospitalization 8/7/2008 44 Male 148 lb 8/21/2008 Belgium
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 10/2/2008 64 Female 10/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Chemotherapeutic Drug Level Increased Other Serious 3/11/2008 4 Male 47 lb 10/7/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Other Serious 11/1/2007 43 Male 10/7/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 11/1/2007 56 Male 10/7/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 12/1/2007 53 Male 10/7/2008 Physician United States
Primary
Concomitant
Death Death 67 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 66 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Death Death 12/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Renal Failure Other Serious Male 1/21/2009 Consumer United Kingdom
Primary
Secondary
Pyrexia Other Serious 10 Male 2/10/2009
Primary
Secondary
Concomitant
No Therapeutic Response Hospitalization 2/6/2009 Female 41 lb 3/4/2009 United States
Primary
Secondary
Sepsis Other Serious 48 Female 3/18/2009 Other Health Professional United States
Primary
Secondary
No Therapeutic Response Hospitalization 2/6/2009 Female 41 lb 3/16/2009 United States
Primary
Secondary
Sepsis Other Serious 48 Female 3/20/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Tumour Invasion Required Intervention 4/1/2007 48 Female 3/26/2009 United States
Primary
Secondary
Thrombocytopenia Other Serious 6/16/2009 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Hospitalization 7/5/2009 Male 163 lb 7/13/2009 United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 57 Male 8/6/2009
Primary
Secondary
Concomitant
Neutropenia Other Serious Male 8/24/2009 Other Health Professional United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 8/12/2009 Male 254 lb 8/19/2009 United States
Primary
Secondary
Pyrexia Hospitalization 4/27/2009 Female 146 lb 10/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/29/2009 Female 99 lb 11/13/2009 United States
Primary
Secondary
Concomitant
Somnolence Other Serious 1/11/2010 United States
Primary
Secondary
Concomitant
Urine Chloride Decreased Other Serious 16 Male 123 lb 3/10/2010 Other Health Professional Canada
Primary
Concomitant
Fat Embolism Other Serious 22 Male 4/2/2010 Other Health Professional Greece
Primary
Secondary
Thrombocytopenia Other Serious 4/15/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Skin Toxicity Other Serious 4/29/2010 United States
Primary
Secondary
Skin Toxicity Death 4/30/2010 Physician United Kingdom
Primary
Secondary
Acute Myeloid Leukaemia Hospitalization 11/20/2010 14 Male 93 lb 12/6/2010 United States
Primary
Secondary
Blood Potassium Decreased Death 1/26/2011 15 Female 118 lb 2/9/2011 Physician United States
Primary
Secondary
Haemorrhage Other Serious 3/1/2011 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/1/2011 Physician United States
Primary
Secondary
Concomitant
Peripheral Nerve Palsy Other Serious 3/28/2011 Physician Italy
Primary
Secondary
Concomitant
Renal Failure Death 3/29/2011 Physician Italy
Primary
Secondary
Concomitant
Pneumonia Cytomegaloviral Death 3/29/2011 Physician Italy
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 3/31/2011 Physician Italy
Primary
Secondary
Concomitant
Candidiasis Hospitalization 4/1/2009 49 Male 128 lb 4/26/2011 United States
Primary
Secondary
Concomitant
Pleural Effusion Death 3/8/2011 15 Female 144 lb 5/24/2011 Physician United States
Primary
Secondary
Cardiotoxicity Other Serious 15 Female 5/27/2011 Other Health Professional Norway
Primary
Secondary
Concomitant
Cardiotoxicity Other Serious 15 Female 5/27/2011 Other Health Professional Norway
Primary
Secondary
Concomitant
Enterocolitis Hospitalization 21 Male 5/27/2011 Other Health Professional Norway
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 21 Male 5/27/2011 Other Health Professional Norway
Primary
Secondary
Concomitant
Septic Shock Death 8 Male 5/27/2011 Other Health Professional Norway
Primary
Secondary
Concomitant
Septic Shock Death 8 Male 5/27/2011 Other Health Professional Norway
Primary
Secondary
Concomitant
Septic Shock Death 8 Male 5/27/2011 Other Health Professional Norway
Primary
Secondary
Concomitant
Neuralgia Other Serious 54 Male 6/24/2011 Other Health Professional Israel
Primary
Secondary
Concomitant
Neoplasm Malignant Death 5 6/25/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Acute Graft Versus Host Disease Other Serious 5 6/25/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Acute Graft Versus Host Disease Death 3 6/25/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Sepsis Death 8/1/2008 54 Male 6/29/2011 Other Health Professional Israel
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 7/14/2011 Other Health Professional France
Primary
Secondary
Toxicity To Various Agents Death 7/14/2011 Other Health Professional France
Primary
Secondary
Toxicity To Various Agents Death 7/14/2011 Other Health Professional France
Primary
Secondary
Hypotension Other Serious 3/8/2011 15 Female 144 lb 7/21/2011 Physician United States
Primary
Secondary
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/5/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 8/8/2011 Physician United States
Primary
Concomitant
Anxiety Other Serious 3/8/2011 15 Female 144 lb 8/11/2011 Consumer United States
Primary
Secondary
Dyspnoea Other Serious 7/25/2011 67 Male 182 lb 8/28/2011 Physician United States
Primary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/30/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 9/2/2011 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 3/9/2011 43 Male 202 lb 9/29/2011 United States
Primary
Secondary
Acute Myeloid Leukaemia Hospitalization 3/9/2011 43 Male 202 lb 9/29/2011 United States
Primary
Secondary
Therapeutic Response Decreased Other Serious 12 Female 10/13/2011 Other Health Professional Jordan
Primary
Secondary
Cardiac Failure Other Serious 10/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Death Death 10/31/2011 Other Health Professional France
Primary
Secondary
Concomitant
Drug Interaction Other Serious 8/23/2011 13 Male 92 lb 11/3/2011 Pharmacist Brazil
Primary
Secondary
Concomitant
Interacting
Neutropenia Other Serious 41 Female 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 26 Male 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 54 Female 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 51 Male 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Cytomegalovirus Infection Other Serious 22 Female 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 49 Female 11/3/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 53 Male 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 69 Male 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 36 Male 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 18 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 26 Male 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Death 41 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 54 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Infection Hospitalization 2/15/2005 17 11/21/2011 United States
Primary
Secondary
Neutropenia Other Serious 22 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Convulsion Life Threatening 6/14/2005 20 11/21/2011 United States
Primary
Secondary
Neutropenia Other Serious 49 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Other Serious 36 Male 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Death 51 Male 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 33 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Neutropenia Other Serious 52 Female 11/15/2011 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/10/2001 11 Male 11/29/2011 Physician United States
Primary
Secondary
Off Label Use Hospitalization 44 Male 11/30/2011 Other Health Professional
Primary
Secondary
Concomitant
Hepatitis B Other Serious 9/15/2011 47 Male 137 lb 12/1/2011 Other Health Professional France
Primary
Secondary
Concomitant
Death Death 12/16/2011 Physician France
Primary
Secondary
Blood Creatinine Increased Other Serious 12/16/2011 Physician France
Primary
Secondary
Adverse Event Other Serious 12/19/2011 Physician France
Primary
Secondary
Cardiac Disorder Other Serious 12/19/2011 Physician France
Primary
Secondary
Lung Neoplasm Malignant Other Serious 12/19/2011 Physician France
Primary
Secondary
Fatigue Hospitalization 9/19/2011 31 Male 12/19/2011 United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 8/13/2009 48 Female 133 lb 12/20/2011 Physician United States
Primary
Secondary
Concomitant
Neutropenic Infection Other Serious 8/22/2010 25 Male 238 lb 12/20/2011 Physician United States
Primary
Secondary
Blood Magnesium Abnormal Hospitalization 8/18/2010 65 Male 238 lb 12/20/2011 Physician United States
Primary
Secondary
Leukopenia Hospitalization 2/7/2009 69 Male 223 lb 12/21/2011 Other Health Professional United States
Primary
Secondary
Pyrexia Other Serious 32 Male 12/21/2011 Physician United States
Primary
Secondary
Lung Neoplasm Malignant Other Serious 12/21/2011 Physician France
Primary
Secondary
Pyrexia Hospitalization 10/1/2001 11 Male 12/22/2011 Consumer United States
Primary
Secondary
Infection Life Threatening 12/8/2001 12 Male 12/23/2011 Physician United States
Primary
Secondary
Lymphopenia Hospitalization 8/18/2010 65 Male 238 lb 12/27/2011 Physician United States
Primary
Secondary
Neurotoxicity Death 12/27/2011 Physician France
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 39 Female 12/29/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 9/19/2011 31 Male 1/24/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Other Serious 1/27/2012 Other Health Professional Korea, Republic Of
Primary
Secondary
Hypotension Hospitalization 9/19/2011 31 Male 1/30/2012 Physician United States
Primary
Secondary
Concomitant
Death Death 2/8/2012 Other Health Professional France
Primary
Secondary

Drug Data