Doxorubicin Hcl combined with Herceptin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Polymyositis Other Serious 54 Female 156 lb 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Papillary Muscle Rupture Hospitalization 1/17/2006 48 Female 154 lb 2/22/2006 Physician Germany
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 1/17/2006 48 Female 154 lb 3/30/2006 Physician Germany
Primary
Secondary
Concomitant
Pneumothorax Required Intervention 6/1/2005 53 Female 4/11/2006 Physician Sweden
Primary
Secondary
Pneumothorax Required Intervention 6/1/2005 53 Female 4/11/2006 Physician Sweden
Primary
Secondary
Ventricular Tachycardia Other Serious 3/1/2004 38 Female 4/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Febrile Neutropenia Hospitalization 11/17/2005 52 Female 272 lb 5/11/2006 Physician Spain
Primary
Secondary
Concomitant
Polymyositis Other Serious 7/7/2005 54 Female 156 lb 5/16/2006 Physician United States
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 10/15/2005 49 Female 190 lb 6/14/2006 Physician United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 1/17/2006 48 Female 154 lb 6/14/2006 Physician Germany
Primary
Secondary
Concomitant
Pneumothorax Required Intervention 6/1/2005 53 Female 6/19/2006 Physician Sweden
Primary
Secondary
Radiation Injury Hospitalization 1/17/2006 48 Female 154 lb 10/3/2006 Physician Germany
Primary
Secondary
Concomitant
Tendon Rupture Hospitalization 1/17/2006 48 Female 154 lb 10/25/2006 Physician Germany
Primary
Secondary
Concomitant
Respiratory Depression Other Serious 9/4/2005 41 Female 148 lb 11/2/2006
Primary
Secondary
Tachycardia Hospitalization 1/17/2006 48 Female 154 lb 11/22/2006 Physician Germany
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/21/2006 52 Female 1/26/2007 Physician India
Primary
Secondary
Hepatic Failure Death 4/1/2006 45 Female 4/10/2007 Physician United Kingdom
Primary
Secondary
Blood Bilirubin Increased Other Serious 11/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Renal Failure Hospitalization 9/1/2007 Female 168 lb 1/31/2008 Physician United Kingdom
Primary
Concomitant
Cardiac Failure Congestive Other Serious Female 3/27/2008 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 8/26/2008 56 Female 187 lb 9/8/2008 Physician Canada
Primary
Secondary
Rash Other Serious 7/28/2008 Female 111 lb 9/5/2008 Pharmacist United States
Primary
Concomitant
Stomatitis Death 4/21/2008 52 Female 11/12/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 64 Female 168 lb 11/25/2008 Physician United States
Primary
Secondary
Pyrexia Hospitalization 8/26/2008 56 Female 187 lb 12/5/2008 Physician Canada
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 58 Female 12/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/26/2008 56 Female 187 lb 12/18/2008 Physician Canada
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 12/19/2008 Physician United Kingdom
Primary
Secondary
Myocarditis Other Serious Female 1/28/2009 Physician Canada
Primary
Secondary
Myocarditis Other Serious Female 1/28/2009 Physician Canada
Primary
Secondary
Myocarditis Other Serious Female 1/29/2009 Physician Canada
Primary
Secondary
Myocarditis Other Serious Female 1/29/2009 Physician Canada
Primary
Secondary
Myocarditis Other Serious Female 1/29/2009 Physician Canada
Primary
Secondary
Myocarditis Other Serious Female 1/29/2009 Physician Canada
Primary
Secondary
Myocarditis Other Serious Female 1/29/2009 Physician Canada
Primary
Secondary
Myocarditis Other Serious Female 1/29/2009 Physician Canada
Primary
Secondary
Myocarditis Other Serious Female 1/29/2009 Physician Canada
Primary
Secondary
Pyrexia Hospitalization 8/26/2008 56 Female 187 lb 2/13/2009 Physician Canada
Primary
Secondary
Concomitant
Atrioventricular Block Complete Disability 6/10/2008 44 Female 3/20/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Abdominal Pain Hospitalization 3/7/2009 60 Female 155 lb 3/24/2009 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/13/2009 73 Female 159 lb 4/7/2009 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/13/2009 73 Female 141 lb 4/22/2009 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/13/2009 73 Female 141 lb 4/24/2009 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/13/2009 73 Female 5/11/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 5/12/2009 Physician United Kingdom
Primary
Secondary
Visual Impairment Other Serious 31 Female 5/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Metastases To Central Nervous System Other Serious 7/1/2002 38 Female 5/18/2009 Consumer United Kingdom
Primary
Secondary
Sudden Death Death 3/23/2009 Female 5/21/2009 Consumer Portugal
Primary
Secondary
Concomitant
Gastric Ulcer Perforation Other Serious 3/7/2009 60 Female 155 lb 5/27/2009 Physician Germany
Primary
Concomitant
Thrombocytopenia Other Serious 6/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Acute Lymphocytic Leukaemia Other Serious 60 Female 7/27/2009 Physician Japan
Primary
Concomitant
Rash Other Serious 8/12/2009 Consumer United Kingdom
Primary
Secondary
Acute Lymphocytic Leukaemia Other Serious 60 Female 9/9/2009 Physician Japan
Primary
Concomitant
Sudden Death Death 3/1/2009 Female 9/15/2009 Consumer Portugal
Primary
Secondary
Concomitant
Staphylococcal Abscess Hospitalization 9/21/2009 Female 217 lb 10/8/2009 United States
Primary
Secondary
Rash Other Serious 6/1/2009 65 Female 10/21/2009 Physician Brazil
Primary
Secondary
Concomitant
Rash Other Serious 6/1/2009 65 Female 11/9/2009 Physician Brazil
Primary
Secondary
Concomitant
Erythema Multiforme Other Serious 9/9/2009 Female 11/16/2009 Consumer United Kingdom
Primary
Secondary
Erythema Multiforme Other Serious 9/9/2009 Female 11/19/2009 Consumer United Kingdom
Primary
Secondary
Urticaria Hospitalization 10/20/2009 49 Female 128 lb 12/30/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 4/1/2008 Female 190 lb 1/27/2010 Physician France
Primary
Secondary
Concomitant
Secretion Discharge Other Serious 32 Female 1/27/2010 Physician Brazil
Primary
Concomitant
Acute Myeloid Leukaemia Life Threatening 1/1/2006 Female 190 lb 2/16/2010 Physician France
Primary
Secondary
Concomitant
Urticaria Hospitalization 10/20/2009 49 Female 128 lb 2/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ovarian Cyst Other Serious 11/1/2003 Female 3/24/2010 United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 54 Female 3/25/2010 Other Health Professional United States
Primary
Secondary
Acute Myelomonocytic Leukaemia Other Serious 54 Female 3/25/2010 Physician United States
Primary
Secondary
Weight Increased Other Serious 11/1/2003 38 Female 4/6/2010 United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 35 Female 4/19/2010 Physician Brazil
Primary
Concomitant
Tendon Disorder Other Serious 30 Female 3 lb 4/21/2010 Physician Ireland
Primary
Concomitant
Weight Increased Other Serious 11/1/2003 38 Female 4/22/2010 United States
Primary
Secondary
Concomitant
Tendon Disorder Other Serious 30 Female 3 lb 5/3/2010 Physician Ireland
Primary
Concomitant
Weight Increased Other Serious 11/1/2003 38 Female 5/7/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/1/2003 38 Female 5/25/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/1/2003 38 Female 6/2/2010 United States
Primary
Secondary
Concomitant
Sudden Death Hospitalization 1/1/2009 57 Female 123 lb 6/10/2010 Portugal
Primary
Secondary
Concomitant
Intracardiac Thrombus Hospitalization 12/14/2007 42 Female 7/7/2010 Other Health Professional Poland
Primary
Secondary
Tendon Disorder Other Serious 5/1/2005 Female 3 lb 7/7/2010 Physician Ireland
Primary
Concomitant
Skin Lesion Other Serious 4/1/2007 57 Female 7/12/2010 Physician Poland
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 2/1/2010 47 Female 7/14/2010 Physician Brazil
Primary
Concomitant
Urticaria Hospitalization 10/20/2009 49 Female 128 lb 7/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/26/2008 56 Female 187 lb 7/23/2010 Physician Canada
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Life Threatening 4/1/2008 58 Female 190 lb 7/30/2010 Physician France
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/1/2003 38 Female 9/1/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/1/2003 38 Female 10/26/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/1/2003 38 Female 11/2/2010 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 11/1/2003 38 Female 12/28/2010 United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 2/16/2011 72 Female 206 lb 3/9/2011 United States
Primary
Secondary
Red Blood Cell Count Decreased Death 8/14/2009 38 Female 126 lb 5/16/2011 Physician Japan
Primary
Concomitant
Cardiotoxicity Other Serious 1/1/2010 43 Female 212 lb 5/31/2011 Physician Brazil
Primary
Secondary
Concomitant
Delirium Other Serious 7/25/2006 43 Female 6/27/2011 United States
Primary
Secondary
Concomitant
Swelling Other Serious 7/25/2006 43 Female 8/22/2011 United States
Primary
Secondary
Concomitant
Breast Disorder Other Serious 1/1/2010 43 Female 212 lb 9/12/2011 Physician Brazil
Primary
Secondary
Concomitant
Atrioventricular Block Complete Hospitalization 44 Female 9/19/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Abnormal Other Serious Female 10/12/2011 Other Health Professional Italy
Primary
Secondary
Disease Progression Other Serious 8/14/2009 38 Female 126 lb 10/18/2011 Physician Japan
Primary
Secondary
Concomitant
Anxiety Hospitalization 12/2/2001 41 Female 116 lb 11/16/2011 United States
Primary
Secondary
Concomitant
Acute Coronary Syndrome Hospitalization 5/4/2001 52 Female 11/17/2011 Physician United States
Primary
Secondary
Acute Coronary Syndrome Hospitalization 2/27/2002 60 11/17/2011 United States
Primary
Secondary
Dyspnoea Hospitalization 1/13/2004 31 Female 150 lb 11/18/2011 United States
Primary
Secondary
Concomitant
Embolism Life Threatening 10/11/2004 49 Female 11/18/2011 Physician United States
Primary
Secondary
Myocardial Infarction Hospitalization 10/9/2000 53 Female 11/18/2011 United States
Primary
Secondary
Embolism Hospitalization 6/26/2004 48 Female 11/18/2011 United States
Primary
Secondary
Ventricular Arrhythmia Life Threatening 9/14/2000 33 Female 11/18/2011 Physician United States
Primary
Secondary
Left Ventricular Dysfunction Hospitalization 4/6/2000 71 Female 11/18/2011 United States
Primary
Secondary
Embolism Hospitalization 10/11/2004 49 11/18/2011 Physician United States
Primary
Secondary
Myocardial Infarction Hospitalization 9/25/2004 50 Female 177 lb 11/18/2011 Physician United States
Primary
Secondary
Dehydration Hospitalization 10/13/2004 45 Female 133 lb 11/18/2011 Physician United States
Primary
Secondary
Headache Hospitalization 5/24/2001 59 Female 11/18/2011 United States
Primary
Secondary
Amnesia Hospitalization 3/13/2006 63 Female 11/18/2011 Physician United States
Primary
Secondary
Dehydration Hospitalization 4/24/2005 36 Female 11/18/2011 Physician United States
Primary
Secondary
Diarrhoea Hospitalization 9/30/2005 71 Female 11/18/2011 Physician United States
Primary
Secondary
Sinus Tachycardia Other Serious 7/19/2004 33 11/18/2011 United States
Primary
Secondary
Non-cardiac Chest Pain Hospitalization 5/13/2002 38 Female 11/18/2011 Physician United States
Primary
Secondary
Vena Cava Thrombosis Hospitalization 1/20/2000 76 Female 11/21/2011 United States
Primary
Secondary
Infection Hospitalization 2/15/2005 17 11/21/2011 United States
Primary
Secondary
Cerebral Ischaemia Hospitalization 1/28/2005 45 11/21/2011 United States
Primary
Secondary
Dyspnoea Life Threatening 5/28/2005 56 Female 11/21/2011 Physician United States
Primary
Secondary
Dehydration Hospitalization 11/5/2004 54 11/21/2011 Physician United States
Primary
Secondary
Convulsion Life Threatening 6/14/2005 20 11/21/2011 United States
Primary
Secondary
Embolism Hospitalization 9/14/2003 61 11/21/2011 Physician United States
Primary
Secondary
Myocardial Infarction Other Serious 1/21/2005 75 Female 11/21/2011 United States
Primary
Secondary
Urinary Tract Pain Hospitalization 11/21/2011 United States
Primary
Secondary
Left Ventricular Dysfunction Hospitalization 8/3/2002 52 Female 102 lb 11/22/2011 United States
Primary
Secondary
Erythema Multiforme Other Serious 8/10/2005 56 Female 11/22/2011 United States
Primary
Secondary
Pericardial Effusion Life Threatening 1/15/2002 55 Female 11/22/2011 United States
Primary
Secondary
Pericardial Effusion Life Threatening 1/29/2004 53 Female 11/22/2011 United States
Primary
Secondary
Peripheral Sensory Neuropathy Other Serious 1/4/2002 39 Female 179 lb 11/22/2011 United States
Primary
Secondary
Concomitant
Hypertriglyceridaemia Hospitalization 5/5/2003 56 Female 137 lb 11/22/2011 United States
Primary
Secondary
Acidosis Life Threatening 5/6/2006 69 Female 137 lb 11/22/2011 United States
Primary
Secondary
Concomitant
Lymphadenopathy Hospitalization 11/23/2001 43 Female 11/23/2011 Physician United States
Primary
Secondary
Constipation Other Serious 1/26/2000 69 Female 12/1/2011 United States
Primary
Secondary
General Physical Health Deterioration Hospitalization 11/16/2011 58 Female 128 lb 12/13/2011 Germany
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 12/7/2011 58 Female 128 lb 12/15/2011 Physician Germany
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 11/16/2011 58 Female 128 lb 12/20/2011 Germany
Primary
Secondary
Concomitant
Pain Other Serious 11/23/2001 52 12/29/2011 United States
Primary
Secondary
Pericardial Effusion Hospitalization 4/1/2001 43 Female 12/29/2011 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/7/2011 58 Female 12/30/2011 Physician Germany
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/10/2012 64 Female 163 lb 1/22/2012 Physician Germany
Primary
Secondary
Peripheral Sensory Neuropathy Other Serious 1/27/2012 Other Health Professional Korea, Republic Of
Primary
Secondary
Neutropenia Other Serious 1/10/2012 44 Female 146 lb 1/27/2012 Physician Germany
Primary
Secondary
Gingival Infection Other Serious 8/1/2011 57 Female 1/30/2012 Physician Lithuania
Primary
Concomitant
Acute Coronary Syndrome Other Serious 5/23/2005 58 Female 2/14/2012 Physician United States
Primary
Secondary
Pyrexia Hospitalization 6/6/2004 49 2/14/2012 Physician United States
Primary
Secondary
Acute Coronary Syndrome Hospitalization 2/27/2002 60 2/16/2012 United States
Primary
Secondary
Left Ventricular Dysfunction Other Serious 9/25/2004 50 Female 177 lb 2/16/2012 United States
Primary
Secondary
Pericardial Effusion Hospitalization 11/21/2004 16 2/16/2012 United States
Primary
Secondary
Respiratory Arrest Hospitalization 3/6/2004 67 Female 2/17/2012 United States
Primary
Secondary
Embolism Hospitalization 10/11/2004 49 Female 2/17/2012 United States
Primary
Secondary
Ventricular Arrhythmia Other Serious 1/11/2002 41 Female 144 lb 2/17/2012 United States
Primary
Secondary

Drug Data