Doxil combined with Velcade

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Hospitalization 9/29/2005 28 Male 147 lb 12/30/2005 Other Health Professional Australia
Primary
Secondary
Concomitant
Neuropathy Death 6/11/2005 Female 1/16/2006 Physician Czech Republic
Primary
Secondary
Myocardial Infarction Death 1/13/2006 Male 123 lb 1/25/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Subcutaneous Abscess Other Serious 1/24/2005 44 Male 1/18/2006 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 4/20/2005 44 Female 106 lb 1/24/2006 Physician Argentina
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/1/2005 65 Male 188 lb 1/30/2006 Other Health Professional United States
Primary
Concomitant
Pyrexia Other Serious 6/19/2005 Male 157 lb 2/10/2006 Physician Netherlands
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Death 1/18/2006 49 Male 123 lb 2/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/12/2006 Female 2/17/2006 Physician Netherlands
Primary
Secondary
Cardiac Failure Chronic Life Threatening 12/1/2005 Male 128 lb 2/17/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 2/12/2006 Female 2/27/2006 Physician Netherlands
Primary
Secondary
Myocardial Ischaemia Life Threatening 12/1/2005 49 Male 123 lb 2/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonitis Death 3/13/2006 Physician United States
Primary
Secondary
Ventricular Hypokinesia Other Serious 12/1/2005 49 Male 123 lb 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 2/24/2006 62 Female 182 lb 3/9/2006 Other Health Professional Poland
Primary
Secondary
Spinal Osteoarthritis Hospitalization 1/30/2006 66 Female 3/13/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Syncope Hospitalization 2/24/2006 62 Female 177 lb 3/24/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 1/20/2006 Male 4/7/2006 Physician United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 3/23/2006 Male 194 lb 4/7/2006 Physician Israel
Primary
Secondary
Platelet Count Decreased Hospitalization 3/23/2006 Male 194 lb 4/12/2006 Physician Israel
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/7/2005 Male 4/13/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/1/2005 Female 123 lb 4/13/2006 Physician Australia
Primary
Secondary
Concomitant
Reflux Oesophagitis Hospitalization 4/7/2006 48 Female 141 lb 4/21/2006 Physician Australia
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 4/7/2006 Female 159 lb 5/2/2006 Physician Spain
Primary
Secondary
Thrombocytopenia Life Threatening 3/24/2006 Female 95 lb 5/3/2006 Physician Singapore
Primary
Secondary
Concomitant
Spinal Disorder 1/1/2001 57 Male 2/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization 4/18/2006 59 Female 179 lb 4/27/2006 Physician Czech Republic
Primary
Secondary
Tumour Lysis Syndrome Hospitalization 4/20/2005 44 Female 106 lb 4/26/2006 Physician Argentina
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 4/2/2006 79 Female 159 lb 4/27/2006 Physician Spain
Primary
Secondary
Troponin T Increased Life Threatening 3/24/2006 58 Female 95 lb 4/28/2006 Physician Singapore
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/4/2005 72 Female 253 lb 2/17/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 3/24/2006 Female 95 lb 5/8/2006 Physician Singapore
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 4/7/2006 Female 159 lb 5/16/2006 Physician Spain
Primary
Secondary
Staphylococcal Sepsis Hospitalization 4/20/2006 62 Female 176 lb 5/9/2006 Physician Poland
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 4/7/2006 79 Female 159 lb 5/9/2006 Physician Spain
Primary
Secondary
Thrombocytopenia Hospitalization 6/20/2005 63 Unknown 5/12/2006 Physician Switzerland
Primary
Secondary
Staphylococcal Sepsis Hospitalization 4/20/2006 62 Female 176 lb 5/18/2006 Physician Poland
Primary
Secondary
Concomitant
Tremor Hospitalization 4/18/2006 59 Female 179 lb 5/23/2006 Physician Czech Republic
Primary
Secondary
Neuropathy Hospitalization 5/1/2006 55 Female 5/26/2006 Physician France
Primary
Concomitant
Thrombocytopenia Hospitalization 6/20/2005 63 6/8/2006 Physician Switzerland
Primary
Secondary
Concomitant
Respiratory Failure Death 9/13/2005 63 6/8/2006 Physician Switzerland
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 5/19/2006 67 Female 6/12/2006 Physician Czech Republic
Primary
Secondary
Thrombocytopenia Death 5/30/2006 59 Male 143 lb 6/12/2006 Physician France
Primary
Secondary
Tongue Disorder Hospitalization 5/20/2006 71 Male 134 lb 6/15/2006 Physician Canada
Primary
Secondary
Reflux Oesophagitis Hospitalization 4/7/2006 48 Female 126 lb 6/15/2006 Physician Australia
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 3/21/2006 Male 194 lb 6/27/2006 Physician Israel
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Hospitalization 5/10/2005 44 Female 101 lb 6/20/2006 Physician Argentina
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/19/2006 59 Male 143 lb 6/26/2006 Physician France
Primary
Secondary
Respiratory Failure Other Serious 9/13/2005 63 6/29/2006 Physician Switzerland
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/20/2005 63 6/29/2006 Physician Switzerland
Primary
Secondary
Concomitant
Neuropathy Peripheral Disability 1/1/2005 Male 134 lb 5/24/2006 Physician United States
Primary
Concomitant
Performance Status Decreased Hospitalization 5/19/2006 67 Female 6/30/2006 Physician Czech Republic
Primary
Secondary
Concomitant
White Blood Cell Count Increased Required Intervention 3/1/2005 73 Male 6/26/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2005 71 Male 157 lb 7/7/2006 Physician Netherlands
Primary
Secondary
Concomitant
Syncope Other Serious 11/24/2005 64 Male 159 lb 7/5/2006 Physician Poland
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 4/7/2006 79 Female 159 lb 7/5/2006 Physician Spain
Primary
Secondary
Inappropriate Antidiuretic Hormone Secretion Life Threatening 6/30/2006 61 Male 190 lb 7/13/2006 Physician France
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 6/12/2006 56 Male 204 lb 7/14/2006 Physician Belgium
Primary
Secondary
Concomitant
Spinal Osteoarthritis Hospitalization 1/30/2006 66 Female 7/24/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Life Threatening 6/30/2006 61 Male 190 lb 7/28/2006 Physician France
Primary
Secondary
Herpes Zoster Hospitalization 5/24/2006 71 Male 134 lb 7/31/2006 Physician Canada
Primary
Secondary
Petechiae Hospitalization 1/30/2006 66 Female 8/1/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 4/7/2006 79 Female 159 lb 8/1/2006 Physician Spain
Primary
Secondary
Vomiting Other Serious 2/12/2006 Female 8/18/2006 Physician Netherlands
Primary
Secondary
Vomiting Hospitalization 7/16/2006 49 Female 8/18/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 2/12/2006 Female 8/30/2006 Physician Netherlands
Primary
Secondary
Pyrexia Hospitalization 5/3/2006 56 Male 220 lb 9/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Tremor Other Serious 4/18/2006 59 Female 179 lb 9/14/2006 Physician Czech Republic
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 4/18/2006 43 Male 152 lb 9/14/2006 Physician Czech Republic
Primary
Secondary
Adrenal Cortical Insufficiency Hospitalization 4/12/2006 54 Female 139 lb 9/21/2006 Physician Poland
Primary
Secondary
White Blood Cell Count Abnormal Hospitalization 12/5/2005 Male 163 lb 9/29/2006 Physician Australia
Primary
Secondary
Concomitant
Syncope Other Serious 1/1/2001 60 Female 168 lb 9/22/2006 Physician United States
Primary
Secondary
Septic Shock Hospitalization 7/13/2006 45 Female 215 lb 9/28/2006 Other Health Professional United States
Primary
Secondary
Delusion Hospitalization 9/26/2006 Female 147 lb 10/10/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/5/2006 68 Female 114 lb 10/11/2006 Physician United States
Primary
Secondary
Concomitant
Escherichia Infection Hospitalization 10/2/2006 56 Female 115 lb 10/13/2006 Physician France
Primary
Secondary
Pneumonitis Death Male 10/16/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 2/6/2006 Female 10/27/2006 Physician Netherlands
Primary
Secondary
Thrombocytopenia Hospitalization 10/10/2006 62 Male 10/19/2006 Physician Austria
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 10/2/2006 56 Female 115 lb 10/23/2006 Physician France
Primary
Secondary
Thrombocytopenia Hospitalization 10/10/2006 62 Male 10/26/2006 Physician Austria
Primary
Secondary
Concomitant
Tangentiality Hospitalization 9/26/2006 Female 147 lb 11/3/2006 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/27/2005 55 Male 10/26/2006 Physician United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 10/2/2006 56 Female 115 lb 10/26/2006 Physician France
Primary
Secondary
Pituitary Tumour Benign Life Threatening 6/30/2006 61 Male 190 lb 11/8/2006 Physician France
Primary
Secondary
Thrombocytopenia Hospitalization 10/10/2006 62 Male 11/7/2006 Physician Austria
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious 9/9/2006 Female 147 lb 11/21/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 12/5/2005 Male 163 lb 11/22/2006 Physician Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 7/16/2006 49 Female 11/21/2006 Physician United States
Primary
Secondary
Suicidal Ideation Hospitalization 9/26/2006 56 Female 137 lb 11/21/2006 Physician United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 10/14/2006 56 Female 11/20/2006 Physician United States
Primary
Secondary
Tachycardia Other Serious 9/9/2006 56 Female 11/20/2006 Physician United States
Primary
Secondary
Vomiting Other Serious 7/15/2006 49 Female 165 lb 12/8/2006 Physician United States
Primary
Secondary
Concomitant
Cellulitis 4/18/2006 43 Male 152 lb 12/14/2006 Physician Czech Republic
Primary
Secondary
Inappropriate Antidiuretic Hormone Secretion Life Threatening 6/30/2006 61 Male 190 lb 12/28/2006 Physician France
Primary
Secondary
Septic Shock Hospitalization 7/13/2006 45 Female 215 lb 1/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 6/12/2006 56 Male 204 lb 1/11/2007 Physician Belgium
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/13/2006 45 Female 215 lb 1/29/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/10/2006 62 Male 2/1/2007 Physician Austria
Primary
Secondary
Concomitant
Alveolitis Allergic Hospitalization 12/4/2006 62 Male 226 lb 3/1/2007 Physician United States
Primary
Secondary
Pulmonary Hypertension Other Serious 1/1/2006 66 Male 226 lb 3/9/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2006 66 Male 226 lb 3/22/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/6/2005 Female 154 lb 4/20/2007 Physician Poland
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/6/2005 69 Female 154 lb 4/19/2007 Other Health Professional Poland
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/19/2006 59 Male 143 lb 5/11/2007 Physician France
Primary
Secondary
Aspartate Aminotransferase Increased Other Serious 4/16/2007 Male 244 lb 5/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/9/2007 78 Female 173 lb 6/6/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/21/2007 32 Female 101 lb 6/14/2007 Physician Italy
Primary
Secondary
Weight Decreased Required Intervention 3/8/2007 73 Male 177 lb 6/20/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2006 78 Female 173 lb 6/29/2007 Physician United States
Primary
Secondary
Concomitant
Multiple Myeloma Death 4/22/2007 7/5/2007 Physician South Africa
Primary
Secondary
Convulsion Hospitalization Female 5/24/2007 Physician United States
Primary
Concomitant
Skin Lesion Other Serious 3/9/2007 78 Female 173 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Required Intervention 4/5/2007 73 Male 5/24/2007 Physician United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 4/16/2007 50 Male 244 lb 5/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Disease Progression Hospitalization 4/22/2007 1 Unknown 7/6/2007 Physician South Africa
Primary
Secondary
Supraventricular Tachycardia Life Threatening 3/11/2007 78 Female 7/17/2007 Physician United States
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 7/8/2007 41 Female 109 lb 7/18/2007 Physician United States
Primary
Secondary
Weight Decreased Other Serious 6/1/2006 78 Female 173 lb 7/20/2007 Physician United States
Primary
Secondary
Concomitant
Sciatica Hospitalization 7/26/2007 67 Male 206 lb 8/9/2007 Physician United States
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/13/2006 61 Female 461 lb 8/17/2007 Physician Canada
Primary
Secondary
Thrombocytopenia Hospitalization 5/19/2006 59 Male 143 lb 8/22/2007 Physician France
Primary
Secondary
Toxicologic Test Abnormal Hospitalization 7/8/2007 41 Female 109 lb 8/31/2007 Physician United States
Primary
Secondary
Malaise Hospitalization 8/3/2007 56 Male 9/7/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/26/2007 67 Male 206 lb 9/27/2007 Physician United States
Primary
Secondary
Concomitant
Skin Nodule Other Serious 70 Male 200 lb 10/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2006 66 Male 226 lb 10/23/2007 Physician United States
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious 10/29/2007 Male 184 lb 11/6/2007 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2006 66 Male 226 lb 11/2/2007 Physician United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/20/2007 68 Female 128 lb 11/5/2007 Physician Italy
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 1/1/2006 66 Male 226 lb 11/9/2007 Physician United States
Primary
Secondary
Concomitant
Infusion Related Reaction Other Serious 10/2/2007 Male 11/20/2007 Other Health Professional United States
Primary
Secondary
Blood Cholesterol Increased Other Serious 1/1/2007 Male 12/6/2007 Consumer United States
Primary
Secondary
Treatment Failure Hospitalization 5/19/2006 59 Male 65 lb 12/5/2007 Physician France
Primary
Secondary
Microangiopathic Haemolytic Anaemia Other Serious 10/1/2007 50 Female 12/18/2007 Physician United States
Primary
Secondary
Microangiopathic Haemolytic Anaemia Hospitalization Female 12/14/2007 Physician United States
Primary
Secondary
Microangiopathic Haemolytic Anaemia Other Serious 12/21/2007 Physician United States
Primary
Secondary
Platelet Count Decreased Hospitalization 10/1/2007 50 Female 12/19/2007 Physician United States
Primary
Secondary
Microangiopathic Haemolytic Anaemia Hospitalization 10/1/2007 50 Female 1/2/2008 Physician United States
Primary
Secondary
Microangiopathic Haemolytic Anaemia Other Serious 1/2/2008 Physician United States
Primary
Secondary
Pericarditis Hospitalization 12/18/2007 64 Male 153 lb 12/26/2007 Pharmacist United States
Primary
Concomitant
Convulsion Other Serious 60 Male 1/9/2008 Other Health Professional United States
Primary
Secondary
Vomiting Hospitalization 12/20/2007 73 Male 191 lb 1/4/2008 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 12/18/2007 64 Male 153 lb 1/10/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Other Serious 11/13/2007 Female 1/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 11/13/2007 53 Female 1/11/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/9/2008 68 Female 123 lb 1/17/2008 Physician United States
Primary
Secondary
Thrombocytopenia Hospitalization 9/17/2007 71 Male 141 lb 1/18/2008 Physician United States
Primary
Secondary
Concomitant
Lymphopenia Hospitalization 1/9/2008 68 Female 123 lb 1/25/2008 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 2/11/2008 Physician United States
Primary
Secondary

Drug Data