Docetaxel combined with Herceptin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Febrile Neutropenia Other Serious 2/6/2006 Physician United States
Primary
Secondary
Diarrhoea Hospitalization Female 5/26/2006 Physician Ireland
Primary
Concomitant
Multi-organ Failure Life Threatening 52 Female 5/26/2006 Consumer Spain
Primary
Secondary
Concomitant
Sepsis Death Female 6/14/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/16/2006 49 Female 174 lb 6/20/2006 Physician Germany
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 60 Female 6/19/2006 Physician France
Primary
Concomitant
Visual Acuity Reduced Disability 6/1/2005 57 Female 7/11/2006 Physician Spain
Primary
Concomitant
Neutropenia Other Serious 6/21/2006 56 Female 168 lb 7/21/2006 Physician United States
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 52 Female 7/27/2006 Other Health Professional Spain
Primary
Secondary
Vomiting Hospitalization 6/8/2006 63 Female 212 lb 8/2/2006 Physician Germany
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 52 Female 7/27/2006 Spain
Primary
Secondary
Neutropenia Other Serious 6/21/2006 56 Female 168 lb 8/11/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/8/2006 63 Female 212 lb 8/14/2006 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 5/16/2006 49 Female 174 lb 8/16/2006 Physician Germany
Primary
Secondary
Concomitant
Hallucination 76 Female 99 lb 9/19/2006 Consumer United States
Primary
Secondary
Concomitant
Mucosal Inflammation Other Serious 5/15/2006 31 Female 9/28/2006 Other Health Professional Spain
Primary
Interacting
Mucosal Inflammation Life Threatening 5/15/2006 34 Male 216 lb 10/3/2006 Other Health Professional Spain
Primary
Secondary
Weight Increased Other Serious 1/1/2006 43 Female 11/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 12/11/2006 59 Female 12/26/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/1/2006 44 Female 3/21/2007 Physician Ireland
Primary
Secondary
Dermatomyositis Disability 10/1/2006 Female 4/9/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/1/2006 42 Female 125 lb 4/17/2007 United Kingdom
Primary
Concomitant
Tachycardia Other Serious 6/1/2006 Female 4/30/2007 Physician Panama
Primary
Secondary
Osteonecrosis Hospitalization 12/18/2006 70 Female 5/5/2007 Japan
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/18/2006 70 Female 5/5/2007 Japan
Primary
Secondary
Concomitant
Periodontitis Hospitalization 12/18/2006 70 Female 5/13/2007 Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/1/2006 42 Female 125 lb 6/19/2007 United Kingdom
Primary
Concomitant
Wound Debridement Other Serious 1/1/2001 Female 167 lb 7/19/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2001 Female 167 lb 7/19/2007 United States
Primary
Secondary
Concomitant
Bradycardia Other Serious 10/3/2006 Female 183 lb 8/2/2007 Consumer United Kingdom
Primary
Interacting
Tooth Extraction Hospitalization 1/31/2006 63 Female 8/14/2007 Japan
Primary
Concomitant
Tooth Extraction Hospitalization 1/31/2006 63 Female 8/28/2007 Japan
Primary
Concomitant
Tooth Extraction Hospitalization 1/31/2006 63 Female 8/28/2007 Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/13/2007 52 Female 139 lb 9/20/2007 Consumer China
Primary
Concomitant
Pleurisy Hospitalization 29 Female 9/27/2007 Physician Sweden
Primary
Concomitant
Tooth Extraction Hospitalization 1/31/2006 63 Female 10/2/2007 Japan
Primary
Concomitant
Chest Pain Hospitalization 7/8/2007 59 Female 140 lb 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Jaundice Hospitalization 9/1/2007 Female 165 lb 10/11/2007 Consumer United Kingdom
Primary
Concomitant
Bronchial Hyperreactivity Other Serious 12/11/2006 Female 106 lb 10/12/2007 Consumer United Kingdom
Primary
Concomitant
Periodontitis Hospitalization 12/18/2006 70 Female 10/19/2007 Japan
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious 44 Female 11/8/2007 Physician United States
Primary
Concomitant
Blood Bilirubin Increased Other Serious 11/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Renal Failure Other Serious 61 Female 12/5/2007 Consumer United Kingdom
Primary
Concomitant
Pericardial Effusion Other Serious 11/2/2007 Female 164 lb 12/14/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 11/13/2007 Female 12/19/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious 10/15/2007 Female 164 lb 1/24/2008 Physician United States
Primary
Concomitant
Tumour Marker Increased Other Serious 1/1/2000 67 Female 167 lb 2/14/2008 United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 2/22/2008 Consumer United Kingdom
Primary
Secondary
Upper Gastrointestinal Haemorrhage Death 2/29/2008 Consumer United Kingdom
Primary
Secondary
Tumour Marker Increased Other Serious 1/1/2000 67 Female 167 lb 3/3/2008 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Female 3/13/2008 Consumer United States
Primary
Concomitant
Clostridial Infection Hospitalization 12/10/2007 3/17/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 45 Female 3/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 12/10/2007 41 3/14/2008 United Kingdom
Primary
Secondary
Concomitant
Clostridial Infection Hospitalization 12/10/2007 41 3/12/2008 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/13/2007 Female 4/3/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/14/2008 Female 207 lb 4/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/14/2008 Female 207 lb 4/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2000 67 Female 167 lb 4/12/2008 United States
Primary
Secondary
Concomitant
Pericarditis Other Serious Female 4/23/2008 Consumer United Kingdom
Primary
Concomitant
Sepsis Hospitalization 3/14/2008 Female 207 lb 4/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/14/2008 Female 207 lb 4/29/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/24/2008 Female 197 lb 5/2/2008 Physician United States
Primary
Concomitant
Sepsis Hospitalization 3/14/2008 Female 207 lb 5/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Septic Shock Hospitalization 3/14/2008 Female 207 lb 5/20/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Pericarditis Other Serious 3/26/2008 Female 5/20/2008 Consumer United Kingdom
Primary
Concomitant
Vocal Cord Paralysis Other Serious 1/1/2000 Female 167 lb 6/2/2008 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/14/2008 Female 207 lb 6/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/14/2008 Female 207 lb 6/9/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 3/27/2008 Physician United States
Primary
Secondary
Sepsis Death 3/1/2008 Female 7/1/2008 Physician Germany
Primary
Concomitant
Hypertension Life Threatening 6/19/2008 Female 7/3/2008 Consumer United Kingdom
Primary
Secondary
Sepsis Death 3/1/2008 Female 7/11/2008 Physician Germany
Primary
Concomitant
Colitis Hospitalization Female 189 lb 7/17/2008 Other Health Professional United States
Primary
Concomitant
Metrorrhagia Other Serious 7/13/2008 Female 8/5/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 7/6/2008 Female 8/13/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Intestinal Perforation Life Threatening 7/29/2008 Female 8/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Hospitalization 6/16/2008 Female 8/28/2008 Physician France
Primary
Concomitant
Performance Status Decreased Hospitalization 7/17/2008 41 Female 9/2/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Intestinal Perforation Life Threatening 7/29/2008 Female 9/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 9/1/2008 70 Female 9/16/2008 Physician Germany
Primary
Concomitant
Osteonecrosis Other Serious 5/1/2008 Female 9/17/2008 Physician Germany
Primary
Secondary
Ejection Fraction Decreased Hospitalization 58 Female 9/29/2008 Consumer United Kingdom
Primary
Concomitant
Tooth Extraction Hospitalization 1/31/2006 Female 10/20/2008 Japan
Primary
Concomitant
Performance Status Decreased Hospitalization 7/17/2008 41 Female 10/21/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Tooth Extraction Hospitalization 1/31/2006 Female 10/28/2008 Japan
Primary
Concomitant
Nausea Other Serious 2/1/2008 Female 11/10/2008 Physician United Kingdom
Primary
Concomitant
Stomatitis Other Serious 11/2/2008 Female 11/13/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/31/2006 Female 12/2/2008 Japan
Primary
Concomitant
Stomatitis Other Serious 11/2/2008 Female 12/4/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 11/18/2003 Female 12/19/2008 Japan
Primary
Concomitant
Blood Bilirubin Increased Other Serious 12/19/2008 Physician United Kingdom
Primary
Secondary
Gastrointestinal Haemorrhage Hospitalization 12/5/2008 Female 12/24/2008 Physician United States
Primary
Secondary
Haemorrhoids Hospitalization 12/5/2008 Female 175 lb 1/6/2009 Physician United States
Primary
Secondary
Concomitant
Carpal Tunnel Syndrome Other Serious Female 1/9/2009 Physician United Kingdom
Primary
Concomitant
Carpal Tunnel Syndrome Disability 12/9/2008 Female 1/20/2009 Consumer United Kingdom
Primary
Concomitant
Stomatitis Other Serious 11/2/2008 Female 1/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Scar Other Serious Female 1/27/2009 Consumer United Kingdom
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 12/12/2008 Female 1/27/2009 Consumer France
Primary
Secondary
Concomitant
Supraventricular Tachycardia Other Serious Female 3/4/2009 Consumer United Kingdom
Primary
Concomitant
Neutropenia Other Serious 1/1/2009 54 Female 3/4/2009 Other Health Professional United States
Primary
Secondary
Intestinal Perforation Life Threatening 7/29/2008 Female 3/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Toothache Other Serious 1/18/2007 Female 132 lb 3/13/2009 Physician Japan
Primary
Concomitant
Skin Exfoliation Other Serious 12/29/2008 Female 3/24/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Scar Other Serious Female 3/30/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Drug Hypersensitivity Life Threatening 6/19/2008 Female 4/9/2009 Consumer United Kingdom
Primary
Secondary
Stomatitis Other Serious 11/2/2008 Female 4/10/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Toothache Other Serious 1/18/2007 Female 132 lb 4/20/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 5/6/2009 Female 5/11/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 5/6/2009 Female 5/18/2009 Consumer United States
Primary
Concomitant
Metastases To Liver Other Serious 36 Female 5/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 3/23/2009 Female 5/21/2009 Consumer Portugal
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 60 Female 5/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Stomatitis Other Serious 5/29/2009 Physician Greece
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/8/2009 Female 6/2/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Dermatosis Other Serious 80 Female 6/2/2009 Physician Germany
Primary
Secondary
Thrombocytopenia Other Serious 4/30/2009 Female 6/4/2009 Physician United Kingdom
Primary
Secondary
Neutropenia Hospitalization 5/8/2009 Female 6/8/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Stomatitis Other Serious 6/12/2009 Physician Greece
Primary
Secondary
Concomitant
Primary Sequestrum Hospitalization 12/18/2006 70 Female 6/18/2009 Japan
Primary
Secondary
Concomitant
Photodermatosis Other Serious 5/2/2009 Female 6/19/2009 Physician Germany
Primary
Secondary
Concomitant
Metastases To Central Nervous System Other Serious 6/5/2009 50 Female 6/25/2009 Consumer China
Primary
Secondary
Stomatitis Other Serious Female 6/26/2009 Consumer United Kingdom
Primary
Secondary
Thrombocytopenia Life Threatening 4/30/2009 Female 6/26/2009 Physician Germany
Primary
Secondary
Vomiting Other Serious Female 7/6/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 6/29/2009 62 Female 7/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Neutropenia Hospitalization 5/8/2009 Female 7/23/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Viral Myocarditis Other Serious 6/29/2009 62 Female 7/24/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 56 Female 8/7/2009 Other Health Professional United Kingdom
Primary
Secondary
Dyspnoea Hospitalization 5/8/2009 Female 158 lb 8/11/2009 Consumer United States
Primary
Secondary
Concomitant
Radiation Pneumonitis Other Serious 6/25/2009 50 Female 8/19/2009 Consumer United Kingdom
Primary
Concomitant
Pancreatitis Acute Other Serious 60 Female 8/25/2009 Other Health Professional United States
Primary
Secondary
Viral Myocarditis Other Serious 1/1/2009 62 Female 8/27/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 8/17/2009 64 Female 8/27/2009 Physician United States
Primary
Secondary
Sudden Death Death 3/1/2009 Female 9/15/2009 Consumer Portugal
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 8/17/2009 Female 100 lb 9/17/2009 Physician United States
Primary
Secondary
Demyelination Other Serious 45 Female 9/17/2009 Consumer United States
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 9/4/2009 Female 9/18/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Intestinal Perforation Life Threatening 7/29/2008 Female 9/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death Female 9/23/2009 Consumer United States
Primary
Concomitant
Intestinal Perforation Life Threatening 7/29/2008 Female 9/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Other Serious Female 10/6/2009 Physician United Kingdom
Primary
Secondary
Unevaluable Event Hospitalization Female 10/8/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Intestinal Perforation Life Threatening 7/29/2008 Female 10/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 11/6/2007 63 Female 168 lb 10/26/2009 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 9/4/2009 Female 10/27/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Nephropathy Toxic Other Serious 51 Female 11/4/2009 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Hospitalization 5/1/2008 37 Female 11/5/2009 Consumer United Kingdom
Primary
Secondary
Tumour Lysis Syndrome Life Threatening 2/27/2002 Male 11/6/2009 Physician Brazil
Primary
Secondary
Subarachnoid Haemorrhage Death 10/5/2001 Female 147 lb 11/6/2009 Physician Japan
Primary
Secondary
Concomitant

Drug Data