Diphenhydramine combined with Ranitidine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombocytopenia Life Threatening 39 Male 1/19/2006 Other Health Professional United States
Primary
Concomitant
Troponin I Increased 11/23/2004 53 Female 207 lb 1/27/2006 Physician United States
Primary
Concomitant
Hypoaesthesia 9/1/2005 50 Female 216 lb 2/6/2006 Physician United States
Primary
Concomitant
Hypertension Life Threatening 10/20/2005 Male 201 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Urticaria Other Serious 2/23/2006 55 Male 228 lb 4/7/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Urticaria Other Serious 2/23/2006 55 Male 228 lb 4/14/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 10/24/2005 79 Female 2/13/2006 United States
Primary
Concomitant
Urticaria Other Serious 7/21/2006 0 Male 17 lb 8/25/2006 United States
Primary
Secondary
Concomitant
Urticaria Other Serious 2/28/2006 55 Male 228 lb 9/1/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Ear Congestion 10/15/2007 48 Female 110 lb 4/17/2008 Pharmacist United States
Primary
Concomitant
Infusion Related Reaction Other Serious 10/13/2008 61 Male 3/25/2009 Physician United States
Primary
Concomitant
Hypersensitivity Hospitalization 12/23/2008 50 Male 172 lb 3/25/2009 Other Health Professional United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 3/18/2009 57 Male 3/26/2009 Consumer United States
Primary
Secondary
Concomitant
Mouth Ulceration Other Serious 1/16/2009 Male 243 lb 4/1/2009 United States
Primary
Concomitant
Infusion Related Reaction Other Serious 59 Female 4/2/2009 Physician United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 10/7/1999 40 Male 210 lb 4/3/2009 United States
Primary
Concomitant
Surgery Hospitalization 78 Female 10/18/2009 United States
Primary
Concomitant
Atrial Fibrillation Other Serious 70 Male 10/23/2009 Physician United States
Primary
Secondary
Oxygen Saturation Decreased Required Intervention 9/23/2009 58 Female 115 lb 9/24/2009 Pharmacist United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 7 Male 57 lb 10/28/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 10/26/2009 United States
Primary
Concomitant
Atrial Fibrillation Other Serious 70 Male 11/5/2009 Physician United States
Primary
Secondary
Unresponsive To Stimuli Hospitalization 78 Female 1/11/2010 United States
Primary
Concomitant
Drug Ineffective Other Serious 12/15/2009 24 Female 239 lb 2/11/2010 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 76 2/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 4/23/2010 61 Female 199 lb 5/4/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 5/10/2010 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 78 Female 117 lb 4/26/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 72 Male 5/12/2010 Other Health Professional United States
Primary
Secondary
Weight Decreased Other Serious 7/1/2001 50 Female 162 lb 5/13/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/27/2010 48 Male 5/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 5/27/2010 56 Female 224 lb 6/4/2010 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 6/15/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2004 6/17/2010 United States
Primary
Concomitant
Gastric Ulcer Hospitalization 4/23/2010 61 Female 199 lb 6/23/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2001 50 Female 162 lb 6/25/2010 United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 1/1/2007 69 Female 148 lb 7/1/2010 Lawyer United States
Primary
Secondary
Concomitant
Pneumonia Life Threatening 11/22/2009 14 Male 165 lb 7/2/2010 Physician United States
Primary
Secondary
Concomitant
Injection Site Reaction Hospitalization 1/27/2010 52 Female 153 lb 7/17/2010 Consumer France
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/4/2007 69 Female 326 lb 7/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Hot Flush Other Serious 68 Female 116 lb 7/22/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 7/25/2007 50 Male 7/27/2010 Physician India
Primary
Secondary
Concomitant
Splenomegaly Required Intervention 12/3/2006 9 Female 64 lb 7/23/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 72 Male 8/2/2010 Other Health Professional United States
Primary
Secondary
Pneumonia Life Threatening 11/22/2009 14 Male 165 lb 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Thrombophlebitis Superficial Hospitalization 4/23/2010 61 Female 196 lb 8/4/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 11/30/1992 61 Female 150 lb 8/5/2010 United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 7/14/2010 30 Female 183 lb 8/10/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 6/29/2010 53 Female 130 lb 8/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 1/9/2004 41 Female 285 lb 8/11/2010 United States
Primary
Concomitant
Pneumonia Life Threatening 11/22/2009 14 Male 165 lb 8/11/2010 Physician United States
Primary
Secondary
Concomitant
Proteinuria Other Serious 9/9/2009 64 Female 152 lb 8/24/2010 Other Health Professional United States
Primary
Concomitant
Gastric Ulcer Hospitalization 4/23/2010 61 Female 196 lb 8/25/2010 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 47 Female 160 lb 8/27/2010 United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 8/23/2010 58 Male 132 lb 9/9/2010 Physician United Kingdom
Primary
Concomitant
Hyperphosphataemia Other Serious 8/19/2010 Male 93 lb 9/21/2010 Pharmacist United States
Primary
Concomitant
Hyperphosphataemia Other Serious 8/19/2010 Male 93 lb 10/13/2010 Pharmacist United States
Primary
Concomitant
Dizziness Other Serious 10/15/2010 Female 10/19/2010 Physician Colombia
Primary
Concomitant
Suicide Attempt Other Serious 8/16/2008 48 Female 11/19/2010 Lawyer United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/1/2007 1 Male 18 lb 12/2/2010 Lawyer United States
Primary
Concomitant
Haemoglobin Other Serious Female 12/3/2010 Other Health Professional United States
Primary
Secondary
Respiratory Tract Haemorrhage Other Serious Female 12/3/2010 Other Health Professional United States
Primary
Secondary
Cerebral Ischaemia Other Serious Female 12/3/2010 Other Health Professional United States
Primary
Secondary
White Blood Cell Disorder Other Serious Female 12/3/2010 Other Health Professional United States
Primary
Secondary
Febrile Neutropenia Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Febrile Neutropenia Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Febrile Neutropenia Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Febrile Neutropenia Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Stomatitis Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Stomatitis Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Neutropenic Sepsis Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Ototoxicity Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Ototoxicity Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Nephropathy Toxic Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Peripheral Sensory Neuropathy Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Peripheral Sensory Neuropathy Other Serious 12/13/2010 Physician Greece
Primary
Secondary
Gastrointestinal Perforation Death 1/1/2011 35 Female 126 lb 1/12/2011 Physician Ecuador
Primary
Concomitant
Gastrointestinal Perforation Death 1/1/2011 35 Female 126 lb 1/13/2011 Physician Ecuador
Primary
Concomitant
Dizziness Hospitalization 6/29/2010 53 Female 134 lb 1/10/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Multi-organ Failure Death 7/1/2007 1 Male 18 lb 1/27/2011 Physician United States
Primary
Concomitant
Proteinuria Hospitalization 11/22/2010 13 Female 98 lb 1/20/2011 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/27/2010 48 Male 2/10/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Proteinuria Hospitalization 11/22/2010 13 Female 98 lb 2/8/2011 Physician United States
Primary
Secondary
Concomitant
Hyperhidrosis Other Serious 11/15/2004 42 Female 285 lb 2/23/2011 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 11/22/2010 13 Female 98 lb 2/15/2011 Physician United States
Primary
Secondary
Concomitant
Cholecystitis Chronic Hospitalization 7/1/2009 27 Female 170 lb 3/7/2011 Consumer United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 77 Female 3/7/2011 Other Health Professional United States
Primary
Concomitant
Acute Febrile Neutrophilic Dermatosis Other Serious 77 Female 3/7/2011 Other Health Professional United States
Primary
Concomitant
Hyperlipidaemia Other Serious 11/15/2004 42 Female 285 lb 3/10/2011 Consumer United States
Primary
Concomitant
Akathisia Other Serious 1/1/1984 32 Female 115 lb 2/28/2011 Lawyer United States
Primary
Concomitant
Pancreatitis Hospitalization 4/27/2010 48 Male 3/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Metastases To Meninges Other Serious 1/1/2004 3/25/2011 Physician United States
Primary
Concomitant
Dehydration Hospitalization 6/29/2010 53 Female 134 lb 3/23/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemolytic Anaemia Hospitalization 1/20/2011 38 Female 4/4/2011 Physician United States
Primary
Secondary
Concomitant
Dizziness Hospitalization 2/7/2011 14 Female 98 lb 4/5/2011 Physician United States
Primary
Secondary
Concomitant
Focal Nodular Hyperplasia Other Serious 12/11/2008 29 Female 160 lb 5/10/2011 Lawyer United States
Primary
Secondary
Concomitant
Bronchitis Hospitalization 7/1/2002 51 Female 162 lb 5/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/20/2011 38 Female 6/7/2011 Physician United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 4/3/2011 55 Female 129 lb 6/16/2011 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 4/3/2011 55 Female 129 lb 6/24/2011 Physician United States
Primary
Secondary
Concomitant
Sepsis Life Threatening 2/15/1999 18 Male 11/18/2011 Other Health Professional United States
Primary
Concomitant
Multi-organ Failure Hospitalization 2/15/1999 18 Male 65 lb 11/18/2011 Physician United States
Primary
Concomitant
Multi-organ Failure Hospitalization 2/15/1999 18 Male 11/28/2011 Other Health Professional United States
Primary
Concomitant
Atrial Flutter Hospitalization 69 Male 1/30/2012 Pharmacist United States
Primary
Concomitant
Kidney Malformation Other Serious 24 3/15/2012 Other Health Professional Canada
Primary
Concomitant
Foetal Growth Restriction Other Serious 32 Female 5 lb 3/20/2012 Other Health Professional Canada
Primary
Concomitant
Maternal Exposure Timing Unspecified Congenital Anomaly 32 Female 5 lb 3/26/2012 Other Health Professional Canada
Primary
Concomitant
Type 2 Diabetes Mellitus Death Male 7/3/2012 Physician United States
Primary
Secondary
Concomitant
Neutropenic Sepsis Death 10/18/2011 62 Female 141 lb 3/7/2013 Consumer Us
Primary
Secondary
Concomitant
Septic Shock Death 11/17/2011 51 Female 170 lb 11/8/2012 Physician Br
Primary
Secondary
Concomitant
Abdominal Abscess Hospitalization 11/25/2011 12 Female 81 lb 8/31/2012 Physician Us
Primary
Secondary
Concomitant
Scar Other Serious 9/2011 Male 198 lb 11/26/2012 Consumer Ca
Primary
Concomitant
Pulmonary Function Test Abnormal Death 3/6/2012 50 Female 10/11/2012 Physician Mx
Primary
Concomitant
Thrombocytopenia Other Serious 12/14/2012 Physician Us
Primary
Secondary
Concomitant
Paraesthesia Other Serious 2012 71 Male 120 lb 8/28/2012 Consumer Br
Primary
Concomitant
Off Label Use Other Serious 8/27/2012 67 Male 115 lb 9/7/2012 Pharmacist Br
Primary
Concomitant
Syncope Hospitalization 7/22/2012 Female 185 lb 9/10/2012 Physician Us
Primary
Secondary
Concomitant
Syncope Hospitalization 7/22/2012 56 Female 185 lb 10/18/2012 Physician Us
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/16/2011 60 Male 1/7/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Disability 12/16/2011 60 Male 239 lb 1/9/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Hyperaemia Other Serious 7/12/2012 20 Female 119 lb 9/29/2012 Pharmacist Br
Primary
Concomitant
Wheezing Other Serious Female 94 lb 10/16/2012 Consumer Us
Primary
Concomitant
Erythema Other Serious 9/14/2012 34 Female 124 lb 10/15/2012 Pharmacist Br
Primary
Concomitant
Tachycardia Other Serious 9/25/2012 62 Female 150 lb 10/15/2012 Pharmacist Br
Primary
Concomitant
Off Label Use Other Serious 10/16/2012 Physician Tr
Primary
Secondary
Concomitant
Ocular Hyperaemia Other Serious 10/11/2012 47 Female 190 lb 10/31/2012 Pharmacist Br
Primary
Concomitant
Off Label Use Other Serious 10/15/2012 62 Female 75 lb 11/1/2012 Pharmacist Br
Primary
Concomitant
Unresponsive To Stimuli Other Serious 35 Female 11/2/2012 Other Health Professional Country Not Specified
Primary
Secondary
Toxicity To Various Agents Other Serious 35 Female 11/7/2012 Other Health Professional Us
Primary
Secondary
Leukopenia Hospitalization 10/23/2012 85 Female 137 lb 1/22/2013 Physician Br
Primary
Secondary
Concomitant
Vomiting Other Serious 11/14/2012 Physician Tr
Primary
Secondary
Concomitant
Leukopenia Death 10/23/2012 84 Female 137 lb 2/15/2013 Physician Br
Primary
Secondary
Concomitant
Atrial Fibrillation Hospitalization 11/7/2012 Male 237 lb 11/20/2013 Physician Us
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 63 Male 135 lb 11/21/2012 Consumer Us
Primary
Concomitant
Hyperaemia Other Serious 11/12/2012 56 Female 149 lb 2/5/2013 Pharmacist Br
Primary
Concomitant
Pruritus 6/7/2012 76 Female 11/28/2012 Pharmacist Us
Primary
Concomitant
Hyperaemia Other Serious 11/8/2012 57 Female 202 lb 12/5/2012 Pharmacist Br
Primary
Concomitant
Unresponsive To Stimuli Other Serious 35 Female 12/11/2012 Other Health Professional Us
Primary
Secondary
Acute Respiratory Distress Syndrome Hospitalization 9/19/2012 47 Male 209 lb 10/30/2012 Consumer De
Primary
Concomitant
Acute Respiratory Distress Syndrome Hospitalization 11/4/2012 47 Male 209 lb 1/21/2013 Consumer De
Primary
Concomitant
Tachycardia Other Serious 11/30/2012 35 174 lb 12/31/2012 Pharmacist Br
Primary
Concomitant
Urticaria Other Serious 11/20/2012 Male 192 lb 12/24/2012 Pharmacist Us
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 12/19/2012 Female 135 lb 12/19/2012 Physician Us
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Disability 12/16/2011 60 Male 238 lb 1/9/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 12/16/2011 60 Male 238 lb 1/10/2013 Physician Gb
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 12/16/2011 60 Male 238 lb 1/15/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Hyperaemia Other Serious 9/21/2012 57 Female 108 lb 2/11/2013 Pharmacist Br
Primary
Concomitant
Visual Impairment Other Serious Female 104 lb 10/19/2012 Lawyer Us
Primary
Concomitant
Wheezing Death 11/30/1992 48 Female 151 lb 3/18/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Vitamin D Deficiency Hospitalization 2005 65 Male 12/12/2012 Us
Primary
Concomitant

Drug Data